Abstract: Techniques for performing compression operations on persistently-stored data blocks during read/write commands. A method embodiment performs in-line data compression operations over data blocks referenced by a caller. The in-line data compression operations are performed during execution of a storage input-output (I/O) command, between the event of receipt of the storage I/O command and the event of returning status of the storage I/O command. The storage I/O operation is associated with at least one data group comprising one or more data blocks that are identified by the caller. Upon receipt of the storage I/O command, one or more compression rules are applied to the data blocks to determine one or more compression parameters, which compression parameters are used to form specific compression operations that are performed over at least a portion of the data group. The status pertaining to the execution of the storage I/O operation is returned to the caller.

Abstract: A secure reconfigurable operating mode system includes a hardware device having multiple operating modes and an operating mode selector that is coupled to the hardware device. The operating mode selector has a virtual fusing register that selects an operating mode for the hardware device and a security processor that enables a secure virtual fusing based on documented security files authorizing selection of the operating mode. A method of secure hardware device operating mode reconfiguration is also provided.

Abstract: Heterocyclic compounds of Formula (I): as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Abstract: Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Abstract: Techniques for performing compression operations on persistently-stored data blocks during read/write commands. A method embodiment performs in-line data compression operations over data blocks referenced by a caller. The in-line data compression operations are performed during execution of a storage input-output (I/O) command, between the event of receipt of the storage I/O command and the event of returning status of the storage I/O command. The storage I/O operation is associated with at least one data group comprising one or more data blocks that are identified by the caller. Upon receipt of the storage I/O command, one or more compression rules are applied to the data blocks to determine one or more compression parameters, which compression parameters are used to form specific compression operations that are performed over at least a portion of the data group. The status pertaining to the execution of the storage I/O operation is returned to the caller.

Abstract: A computer-implemented method of managing an inventory of articles includes receiving, by a transfer processor, article information associated with the articles, and identifying, by the transfer processor, one of the articles based on an article identifier. The method also includes retrieving article information based on the identifier, the article information including care information for the one of the articles, and, when the identified article is an article requiring special care, a special care requirement is included in the care information, and preparing the article for transfer based on the care information.

Abstract: The present invention discloses compounds useful in treatment of conditions associated with excessive activity of transforming growth factor beta (TGF-?), particularly type I or activin-like kinase 5 (ALK 5). Specifically, the present invention discloses compound of formula (I) which exhibit inhibitory activity against ALK 5. Method of treating conditions associated with excessive activity (ALK 5) with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.

Abstract: A circuit includes a logic circuit and a driver. The driver includes a first NMOS having a gate coupled to the logic circuit and source coupled to a reference voltage, a PAD coupled to a drain of the first NMOS, and a driver protection circuit. The driver protection circuit includes a second NMOS having a drain coupled to the PAD through a capacitor, source coupled to the reference voltage, and gate coupled to a supply voltage, and a resistor coupled between the drain of the second NMOS and the bulk of the first NMOS. The supply voltage transitions low when an electrostatic discharge (ESD) event raises potential at the PAD with respect to either reference voltage or supply voltage such that the second NMOS turns off, resulting in isolation of the bulk of first NMOS from the reference voltage and coupling of the bulk to the PAD using the capacitor.

Abstract: A fuel tank isolation valve 10, wherein, the shaft 18 is assembled coaxially inside hole 42 of moving plunger 46 of seal sub assembly 16 and then flow limiter 22 is guided over the shaft 18 through guiding hole 34 to maintain sealing seat 36 in parallel with respect to the sealing surface 38 of rubber seal 44 and avoid misalignment of flow limiter 22 with respect to sealing surface 38 during and after the operation; the sealing seat 36 of flow limiter 22 on the sealing surface 38 of the rubber seal 44 fixed into moving plunger 46 of seal sub assembly 16 performs the over pressure relief function; the sealing surface 40 of rubber seal 44 fixed into moving plunger 46 of seal sub-assembly 16 is resting on surface 48 of nozzle body 20 to perform over vacuum relief function; and the rubber seal 44 assist both over pressure relief (OPR) and over vacuum relief (OVR) function.

Abstract: A mechanism is described for facilitating smart monitoring of body dimensions according to one embodiment. A method of embodiments, as described herein, includes receiving a first request to take a first picture of a user, wherein the first picture is taken at a first point in time using a depth-sensing camera; automatically computing first body dimensions relating to a body of the user based on at least one of a first image of the body and first depth information relating to one or more parts of the body, wherein the first image and the first depth information are obtained from the first picture; generate a first three-dimensional (3D) model of the body based on the first body dimensions; and communicating at least one of the first 3D model and the first body dimensions to a display device, wherein the display device to display at least one of the first 3D model and the first body dimensions.

Abstract: There is provided a nanofibrous filter comprising a substrate and self-assembled nanofibers deposited on the substrate. The self-assembled nanofibers comprise ?-conjugated molecules self-assembled by non-covalent interactions, wherein the ?-conjugated molecules are phthalocyanine derivative molecules or diketopyrrolopyrrole derivative molecules. There is also provided a method of preparing the nanofibrous filter.

Abstract: The present invention relates to a phosphomimetic RAGE protein comprising an amino acid sequence that is at least 90% identical to a native mammalian RAGE isoform or fragment thereof wherein at least one serine present in the cytoplasmatic tail of the mammalian RAGE isoform is replaced by a phosphomimetic structure. The invention further relates to a polynucleotide encoding phosphomimetic RAGE protein and a vector comprising the polynucleotide. Finally, the invention relates to a composition comprising carrier and an active pharmaceutical ingredient, selected from the RAGE protein the vector for use in the treatment or prevention of a disease in a patient, wherein the disease is preferably selected from a disease initiated by impaired DNA repair, a disease initiated by increased DNA damage or a disease initiated by increased senescence.

Abstract: Dynamic erasure coding for computing and data storage systems. A method embodiment commences upon accessing a set of fault tolerance policy attributes associated with the computing and data storage system. The topology of the system is analyzed to form mappings between the computing nodes of the system and the availability domains of the system. Based on the fault tolerance policy attributes, the topology, and the generated mapping, a plurality of feasible erasure coding configurations are generated. The feasible erasure coding configurations are scored. One or more high-scoring feasible erasure coding configurations are selected and deployed to the computing and data storage system. The method is repeated when there is a change in the fault tolerance policy attributes or in the topology. Depending on the topology and/or the nature of a change in the topology, more than one erasure coding configurations can be deployed onto the computing and data storage system.

Abstract: Various embodiments described herein relate to an intelligent warning system in a communication service. One embodiment of the present invention analyzes a user's biometric signals and image data of one of the user's in a communication session to determine a distress level. In addition, location data indicating the user's velocity and direction can be used to determine a distress level. If the biometric signals or the image data indicate a distress level that meets or exceeds a threshold level, a notification is automatically sent to a remote user. This can allow a remote user to render assistance to a user in distress, even when the user is unable to communicate one or more conditions.

Abstract: Systems for high-performance computing. A method operates in a distributed storage cluster platform that has a storage pool and computing nodes that concurrently execute foreground tasks and background tasks. A uses interacts with a user interface to input specifications of background task time windows. Background tasks that run within the time frame of a background task time window are permitted to be scheduled at a relatively higher resource usage rate that consumes relatively higher cluster resources than do background task tasks that run outside of the background task time window. When the background task time window closes, the relatively higher resource usage rate of the running cluster background tasks is reduced to a relatively lower resource usage rate. Background tasks can self-observe the background task time windows and/or can be controlled by messages received from a virtualized controller that is designated to perform cluster-wide observations and to make cluster-wide determinations.

Abstract: Systems for ad-hoc analysis of metadata in distributed data storage systems. A distributed storage system comprises computing nodes and a storage pool that is accessible by computing nodes. The storage pool comprises stored information and respective metadata that describes the stored information. Instances of a metadata search engine are installed on the computing nodes such that the metadata search engines have access to both local data stored in the storage pool as well as to networked storage in the storage pool. A user defines metadata management application extensions for extending the metadata search engine using computer programming languages. When executed by the metadata search engine, the extensions perform user-defined functions. A metadata analysis command is associated with the user-defined function and the metadata analysis command is launched from within the metadata search engine to perform the user-defined function over metadata stored in the system.

Abstract: Various embodiments described herein relate to an intelligent warning system in a communication service. One embodiment of the present invention analyzes a user's biometric signals and image data of one of the user's in a communication session to determine a distress level. In addition, location data indicating the user's velocity and direction can be used to determine a distress level. If the biometric signals or the image data indicate a distress level that meets or exceeds a threshold level, a notification is automatically sent to a remote user. This can allow a remote user to render assistance to a user in distress, even when the user is unable to communicate one or more conditions.

Abstract: Various embodiments described herein relate to an intelligent warning system in a communication service. One embodiment of the present invention analyzes a user's biometric signals and image data of one of the user's in a communication session to determine a distress level. In addition, location data indicating the user's velocity and direction can be used to determine a distress level. If the biometric signals or the image data indicate a distress level that meets or exceeds a threshold level, a notification is automatically sent to a remote user. This can allow a remote user to render assistance to a user in distress, even when the user is unable to communicate one or more conditions.

Abstract: Dynamic erasure coding for computing and data storage systems. A method embodiment commences upon accessing a set of fault tolerance policy attributes associated with the computing and data storage system. The topology of the system is analyzed to form mappings between the computing nodes of the system and the availability domains of the system. Based on the fault tolerance policy attributes, the topology, and the generated mapping, a plurality of feasible erasure coding configurations are generated. The feasible erasure coding configurations are scored. One or more high-scoring feasible erasure coding configurations are selected and deployed to the computing and data storage system. The method is repeated when there is a change in the fault tolerance policy attributes or in the topology. Depending on the topology and/or the nature of a change in the topology, more than one erasure coding configurations can be deployed onto the computing and data storage system.

Abstract: Various embodiments described herein relate to coupling textual and emotional communication in a communication service. One embodiment captures an image from a user of an application. Next, an expression is determined from the image. The application then identifies a graphical expression which corresponds to the graphical expression. Finally, the application displays the graphical expression. This can be done for example via a WI-FI network, a cellular network, or other mode of peer-to-peer or server-based communication scheme. The present invention also provides a keyboard service.