Patents by Inventor Vasantha Nagarajan

Vasantha Nagarajan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fermentative production of alcohols
    Patent number: 9909148
    Abstract: The invention relates to the fields of industrial microbiology and alcohol production. The invention also relates to the development of a microorganism capable of producing fermentation products via an engineered pathway, and uses of the microorganism. The invention also relates to the methods to improve cell viability and productivity and the use of recycling and acid washing to increase the yield of fermentation products.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: March 6, 2018
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Bhaskar Bhadra, Ritu Bhalla, Arthur Leo Kruckeberg, Vasantha Nagarajan, Ranjan Patnaik, Wonchul Suh
  • Fermentive production of four carbon alcohols
    Patent number: 9862976
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: January 9, 2018
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive Production of Four Carbon Alcohols
    Publication number: 20170029851
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Application
    Filed: October 18, 2016
    Publication date: February 2, 2017
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive production of four carbon alcohols
    Patent number: 9506071
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: November 29, 2016
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive Production of Isobutanol Using Highly Effective Ketol-Acid Reductoisomerase Enzymes
    Publication number: 20160319307
    Abstract: Ketol-acid reductoisomerase enzymes have been identified that provide high effectiveness in vivo as a step in an isobutanol biosynthetic pathway in bacteria and in yeast. These KARIs are members of a clade identified through molecular phylogenetic analysis called the SLSL Clade.
    Type: Application
    Filed: July 14, 2016
    Publication date: November 3, 2016
    Inventors: Vasantha Nagarajan, Brian James Paul, Wonchul Suh, Jean-Francois Tomb, Rick W. Ye
  • Fermentive Production of Four Carbon Alcohols
    Publication number: 20160186186
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Application
    Filed: March 11, 2016
    Publication date: June 30, 2016
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive production of four carbon alcohols
    Patent number: 9365872
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: June 14, 2016
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Method for the production of isobutanol by recombinant yeast
    Patent number: 9303225
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: April 5, 2016
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Michael Charles Grady, Mehmedalija Jahic, Lori Ann Maggio-Hall, Vasantha Nagarajan, Ranjan Patnaik
  • Fermentive production of four carbon alcohols
    Patent number: 9297029
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: March 29, 2016
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive production of four carbon alcohols
    Patent number: 9297028
    Abstract: Methods for the fermentive production of four carbon alcohols is provided. Specifically, butanol, preferably 1-butanol is produced by the fermentive growth of a recombinant bacterium expressing a 1-butanol biosynthetic pathway.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: March 29, 2016
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Lixuan Lisa Huang, Lori Ann Maggio-Hall, Vasantha Nagarajan, Charles E. Nakamura, Wonchul Suh
  • Butanol tolerance in microorganisms
    Patent number: 9273330
    Abstract: Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from a pyruvate utilizing pathway. Yeast host cells provided herein comprise reduced pyruvate decarboxylase activity and modified adenylate cyclase activity. In embodiments, yeast host cells provided herein comprise resistance to butanol and increased biomass production.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: March 1, 2016
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Michael G. Bramucci, Vasantha Nagarajan
  • FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS
    Publication number: 20150252389
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Application
    Filed: May 19, 2015
    Publication date: September 10, 2015
    Applicant: BUTAMAX ADVANCED BIOFUELS LLC
    Inventors: GAIL K. DONALDSON, ANDREW C. ELIOT, DENNIS FLINT, LORI ANN MAGGIO-HALL, VASANTHA NAGARAJAN
  • FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS
    Publication number: 20150247169
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Application
    Filed: May 19, 2015
    Publication date: September 3, 2015
    Applicant: Butamax Advanced Biofuels LLC
    Inventors: Gail K. DONALDSON, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive production of four carbon alcohols
    Patent number: 9068190
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: June 30, 2015
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive Production of Four Carbon Alcohols
    Publication number: 20150119608
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Application
    Filed: December 30, 2014
    Publication date: April 30, 2015
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • Fermentive production of four carbon alcohols
    Patent number: 8980612
    Abstract: Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: March 17, 2015
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Vasantha Nagarajan, Charles E. Nakamura, Jean-Francois Tomb
  • Recombinant host cell comprising a diol dehydratase
    Patent number: 8962298
    Abstract: Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: February 24, 2015
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Vasantha Nagarajan, Charles E. Nakamura, Jean-Francois Tomb
  • Fermentive production of four carbon alcohols
    Patent number: 8951774
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: February 10, 2015
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan
  • FERMENTATIVE PRODUCTION OF ALCOHOLS
    Publication number: 20150037855
    Abstract: The invention relates to the fields of industrial microbiology and alcohol production. The invention also relates to the development of a microorganism capable of producing fermentation products via an engineered pathway, and uses of the microorganism. The invention also relates to the methods to improve cell viability and productivity and the use of recycling and acid washing to increase the yield of fermentation products.
    Type: Application
    Filed: December 28, 2012
    Publication date: February 5, 2015
    Inventors: Bhaskar Bhadra, RITU Bhalla, Arthur Leo Kruckeberg, Vasantha Nagarajan, Ranjan Patnaik, Wonchul Suh
  • Production of isobutanol by a microorganism with enhanced acetolactate synthase activity
    Patent number: 8945859
    Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 3, 2015
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Gail K. Donaldson, Andrew C. Eliot, Dennis Flint, Lori Ann Maggio-Hall, Vasantha Nagarajan