Abstract: The specification describes a white balance enclosure for use with a tip of a multi-viewing elements endoscope. The white balance enclosure is used to provide a reference white background to the plurality of viewing elements when the tip is positioned within the white balance enclosure and a white balance circuit is used to calculate and store reference white balance values based on white field/test feed signals generated by the plurality of viewing elements exposed to the reference white background.

Abstract: There is provided herein, an electronic circuit board assembly for a tip section of a multiple viewing elements endoscope, the assembly including a base board configured to carry a first metal frame to support a front looking viewing element and a second metal frame to support a side looking viewing element; and a flexible illumination circuit board comprising a front foldable panel configured to carry three sets of front illuminators for essentially illuminating the field of view (FOV) of the front looking viewing element, and a side foldable panel configured to carry a set of side illuminators for essentially illuminating the field of view (FOV) of the side looking viewing element.

Abstract: An optical assembly adapted to be positioned within an endoscope tip and having three modular camera units, comprising: a front modular camera unit defined by a front central axis and a first and second side modular camera units defined by first and second side central axes that are substantially parallel to one another and substantially perpendicular to the front central axis. Each modular camera unit further comprises a holder for housing an associated optical element and an image sensor in data communication with a corresponding printed circuit board. The front, first side and second side modular camera units are respectively positioned in first, second and third compartments of an assembly holder.

Abstract: An endoscope assembly has a tip that includes at least one front-pointing camera and at least one front illuminator associated therewith, at least one side-pointing camera and at least one side illuminator associated therewith, a first front service channel with a first exit point, and a second front service channel with a second exit point where the first and the second service channel exit points are located in close proximity on the front distal end of the tip. Further, an interior volume of the tip is in a range of 2.75 cm3 to 3.5 cm3, wherein each of the at least two viewing elements is configured to generate a field of view ranging from 120 to 180 degrees, a depth of field ranging from 3 to 100 mm, and a peripheral distortion of less than 80%.

Abstract: An image capturing assembly for use in an endoscope includes a manifold with a base and a casing extending outward from the base, a partially enclosed housing adapted to physically attach to the manifold, a foldable LED carrier substrate capable of carrying a plurality of LEDs, a flexible optical carrier substrate capable of carrying a plurality of camera sensors, and a tip cover adapted to cover the manifold, housing, LED carrier substrate, and optical carrier substrate. The manifold includes at least one continuous channel extending throughout its length. The foldable LED carrier substrate includes a central, forward facing portion, adapted to carry at least one illuminator for a front viewing element, and a pair of arms extending proximally from the central portion. Each arm includes at least one foldable protrusion adapted to carry an illuminator for a side viewing element.

Abstract: There is provided herein an optical system for a tip section of a multi-sensor endoscope, the system comprising: a front-pointing camera sensor; a front objective lens system; a side-pointing camera sensor; and a side objective lens system, wherein at least one of said front and side objective lens systems comprises a front and a rear sub-systems separated by a stop diaphragm, said front sub-system comprises, in order from the object side, a first front negative lens and a second front positive lens, said rear sub-system comprises, in order from the object side, a first rear positive lens, an achromatic sub-assembly comprising a second rear positive lens and a third rear negative lens, wherein the following condition is satisfied: f(first rear positive lens)?1.8f, where f is the composite focal length of the total lens system and f(first rear positive lens) is the focal length of said first rear positive lens.

Abstract: An optical head for an endoscope is fitted with an imaging system comprising a solid state imaging sensor and with an illuminating system comprising illuminating means, e.g. LED's. At least one illuminating means is defined by a parameter, which value is different from the value of the same parameter of the remaining illuminating means. Among the parameters are luminous intensity, luminous intensity distribution angle, and direction of the longitudinal axis of the illuminating means.

Abstract: An apparatus and a method for producing an emulsion of a fuel and an emulsifiable component are disclosed. The apparatus comprises a first cavitation chamber for receiving a first fluid, the first fluid being a first one of the fuel and the emulsifiable component, and wherein the apparatus is arranged to produce a swirling flow of the first fluid in the first cavitation chamber. The apparatus comprises a second cavitation chamber for receiving a second fluid, the second fluid being a second one of the fuel and the emulsifiable component, where the apparatus is arranged to produce a swirling flow of the second fluid in the second cavitation chamber. The first cavitation chamber further comprises an outlet and the first cavitation chamber, the outlet and the second cavitation chamber are arranged coaxially. The second cavitation chamber is arranged to receive the first fluid from the first cavitation chamber through the outlet.

Abstract: The present invention relates generally to the field of endoscopy and specifically to endoscopic apparatus used for endoscopic procedures during which a flexible tube is inserted into the rectum and colon for examination of the colon interior for abnormalities. More particularly, the present invention refers to a control system for supplying a fluid medium, e.g. air, carbon dioxide, water, to the endoscope.

Abstract: An apparatus and a method for cavitating a mixture of a fuel and an additive are disclosed. The apparatus comprises a cavitation stream, the cavitation stream comprising a counter jet device, a jet stroke device and a swirling cavitation device. A mixture of a fuel and additive is arranged to pass through the cavitation stream, wherein the mixture undergoes wave and cavitation processing in the swirling cavitation device. The cavitation apparatus further comprises a resonance chamber and a homogenizer, into which the wave and cavitated mixture is passed to obtain an emulsion of improved homogeneity from an outlet of the homogenizer.

Abstract: A control system for supplying fluid medium to an endoscopic apparatus which comprises an operation handle and an insertion tube provided with an insufflation channel, an irrigation channel and a suction channel extending therealong. The control system is provided with a system control unit with at least one source of a first fluid medium, with a source of a second fluid medium, with a source of vacuum and with a multifunctional connector for bringing the operation handle in fluid and electrical communication with the system control unit. The source of the first fluid medium and the source of the second fluid medium are simultaneously connectable to and disconnectable from the insufflation channel and the irrigation channel.

Abstract: The present invention relates generally to the field of endoscopy and specifically to endoscopic apparatus used for endoscopic procedures during which a flexible tube is inserted into the rectum and colon for examination of the colon interior for abnormalities. More particularly, the present invention refers to a control system for supplying a fluid medium, e.g. air, carbon dioxide, water, to the endoscope.

Abstract: An endoscopic apparatus including an internal unit, adapted to be advanced into a gastrointestinal tract of a patient so as to enable inspection of the tract, an anchor unit, adapted to be held in a position outside the gastrointestinal tract and a flexible sleeve, having a proximal end fixed to the anchor and a distal end fixed to the internal unit, wherein at least a portion of the sleeve between the proximal end distal ends is held initially in a compact state at the internal unit and is arranged to feed out from the internal unit as the internal unit is advanced into the gastrointestinal tract. A method for endoscopic examination is also disclosed.

Abstract: The present invention provides methods for the treatment of tumors, such as spinal metastases, using compositions that permit the introduction of chemotherapeutics intratumorally while concurrently visualizing the procedure. Thus, in certain embodiments, the invention concerns a composition comprising a chemotherapeutic, an alcohol and an iodinated contrast agent (e.g., iodouracil) that may be introduced into the tumor by direct injection through the aid of an imaging device, such as a CT scanner, x-ray machine, fluoroscope or the like. The ability to visualize drug solution permits the faithful introduction of the drug directly into the tumor, as opposed to surrounding tissues, which is enabled through the use of the contrast medium.

Abstract: An endoscopic apparatus for endoscopic examination of a body channel or cavity is described. The endoscopic apparatus comprises an insertion tube with at least one channel, which is in flow communication with the body channel or cavity. The endoscopic apparatus comprises also a pressure relief arrangement fitted with a valve, which is in flow communication with the body channel or cavity. The valve is suitable for preventing an inner pressure within the body channel or cavity to exceed a threshold value.

Abstract: An optical head for an endoscope is fitted with an imaging system comprising a solid state imaging sensor and with an illuminating system comprising illuminating means, e.g. LED's. At least one illuminating means is defined by a parameter, which value is different from the value of the same parameter of the remaining illuminating means. Among the parameters are luminous intensity, luminous intensity distribution angle, and direction of the longitudinal axis of the illuminating means.

Abstract: A control system for supplying fluid medium to an endoscopic apparatus which comprises an operation handle and an insertion tube provided with an insufflation channel, an irrigation channel and a suction channel extending therealong. The control system is provided with a system control unit with at least one source of a first fluid medium, with a source of a second fluid medium, with a source of vacuum and with a multifunctional connector for bringing the operation handle in fluid and electrical communication with the system control unit. The source of the first fluid medium and the source of the second fluid medium are simultaneously connectable to and disconnectable from the insufflation channel and the irrigation channel.

Abstract: An endoscopic apparatus including an internal unit, adapted to be advanced into a gastrointestinal tract of a patient so as to enable inspection of the tract, an anchor unit, adapted to be held in a position outside the gastrointestinal tract and a flexible sleeve, having a proximal end fixed to the anchor and a distal end fixed to the internal unit, wherein at least a portion of the sleeve between the proximal end distal ends is held initially in a compact state at the internal unit and is arranged to feed out from the internal unit as the internal unit is advanced into the gastrointestinal tract. A method for endoscopic examination is also disclosed.

Abstract: An endoscopic apparatus including an internal unit, adapted to be advanced into a gastrointestinal tract of a patient so as to enable inspection of the tract, an anchor unit, adapted to be held in a position outside the gastrointestinal tract and a flexible sleeve, having a proximal end fixed to the anchor and a distal end fixed to the internal unit, wherein at least a portion of the sleeve between the proximal end distal ends is held initially in a compact state at the internal unit and is arranged to feed out from the internal unit as the internal unit is advanced into the gastrointestinal tract.

Abstract: The present invention involves a method of treating cancer using a mutant adenovirus that is targeted to cells with a mutant retinoblastoma pathway. The mutant adenovirus is able to kill the tumor cells without harming the cells with a wild type retinoblastoma pathway.