Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.

Abstract: Paraffin-embedded tissue, which may be disposed on a solid substrate, is prepared by a dry technique that removes paraffin from tissue without adding any liquid to the tissue, thereby rendering the tissue substantially free of paraffin. The dry technique may entail applying heat energy to the tissue effective to melt the paraffin and thereby render it flowable, and applying an electric field. The electric field is effective to impart electrical charge to the paraffin and to move the paraffin out from the tissue due to electrical charge repulsion or attraction, which may be assisted by moving an electrode utilized to generate the electric field relative to the paraffin. The electric field, or both the electric field and the heat energy, may be applied until the tissue is substantially free of paraffin.

Abstract: A nuclear magnetic resonance (NMR) system and method for determining oil and water composition in drilling mud by separating out signals from oil and water in a two dimensional relaxation space wherein the oil and water ratio is a function of the separated out signals. The spin-lattice relaxation time distribution or a spin-spin relaxation time distribution of the sample is measured and a spin-lattice versus spin-spin or a spin-spin versus diffusion two-dimensional procedure is applied to separate the components of the drilling fluid. The signal intensities from the oil and water regions of the one-dimensional or two-dimensional NMR measurements are used to quantify the relative portion of the proton NMR signal from the oil and water and to determine the ratio of oil and water in the drilling mud.

Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.

Abstract: Novel tools and techniques are provided for implementing augmented reality (AR)-based assistance within a work environment. In various embodiments, a computing system might receive, from a camera having a field of view of a work environment, first images of at least part of the work environment, the first images overlapping with a field of view of a user wearing an AR headset; might analyze the received first images to identify objects; might query a database(s) to determine a task associated with a first object(s) among the identified objects; might generate an image overlay providing at least one of graphical icon-based, text-based, image-based, and/or highlighting-based instruction(s) each indicative of instructions presented to the user to implement the task associated with the first object(s); and might display, to the user's eyes through the AR headset, the generated first image overlay that overlaps with the field of view of the user's eyes.

Abstract: Paraffin-embedded tissue is prepared removing paraffin from the tissue. The paraffin is removed by generating an electric field effective to produce plasma and direct charged species of the plasma to the paraffin, thereby rendering the paraffin responsive to the electric field. The electric field may move the paraffin out from the tissue due to electrostatic force. Movement of the paraffin may be assisted by moving an electrode utilized to generate the electric field relative to the paraffin. Movement of the paraffin also may be assisted by applying a solvent and/or heat energy to the tissue.

Abstract: This invention relates to methods and devices for NMR spectroscopy analyzing sealed containers e.g., food and beverage containers and other containers, and particularly according to specific embodiments sealed containers made of a conducting but generally nonferromagnetic metal or other conducting material. As discussed in above referenced applications, many current strategies for contaminant detection require a container to be violated, a process that can destroy the container or product and is impractical in large scale applications. The present invention overcomes these and other problems by providing methods and devices for the detection of contaminants and/or contraband in metal or conducting containers by NMR spectroscopy.

Abstract: This invention relates to apparatus and methods for transferring a tissue section to a slide. The invention also relates to automated systems and methods for transferring a tissue section onto a slide using a bath at ambient temperature and for smoothly mounting a tissue section on a slide.

Abstract: The present invention includes an apparatus and method that facilitates the manual sorting of slides into slide folders. The apparatus includes a horizontal display surface and a controller configured to receive slides and folders into which the slides are to be placed (or sorted). The controller operates components of the apparatus to selectively illuminate the display surface to guide a user in placing folders at multiple folder locations and in sorting the slides into the folders. In one aspect of the invention, the apparatus is configured to allow multiple folders to be stacked at a folder location during the slide sorting process. In these aspects, the apparatus is configured to determine number of folders stacked at each folder location.

Abstract: Methods and apparatus are provided for transfer of a tissue section from a first location to a second location. Thermoplastic material is applied to at least one pin of a tissue section transferring apparatus. The thermoplastic material contacts a tissue section while at least partially melted, and when it cools, substantially solid thermoplastic material holds the tissue section to the at least one pin. A tissue section transferring apparatus comprises a heater block, a heat source, and at least one pin attached to and extending from the heater block.

Abstract: Paraffin-embedded tissue, which may be disposed on a solid substrate, is prepared by a dry technique that removes paraffin from tissue without adding any liquid to the tissue, thereby rendering the tissue substantially free of paraffin. The dry technique may entail applying heat energy to the tissue effective to melt the paraffin and thereby render it flowable, and applying an electric field. The electric field is effective to impart electrical charge to the paraffin and to move the paraffin out from the tissue due to electrical charge repulsion or attraction, which may be assisted by moving an electrode utilized to generate the electric field relative to the paraffin. The electric field, or both the electric field and the heat energy, may be applied until the tissue is substantially free of paraffin.

Abstract: The present invention includes an apparatus and method that facilitates the manual sorting of slides into slide folders. The apparatus includes a horizontal display surface and a controller configured to receive slides and folders into which the slides are to be placed (or sorted). The controller operates components of the apparatus to selectively illuminate the display surface to guide a user in placing folders at multiple folder locations and in sorting the slides into the folders. In one aspect of the invention, the apparatus is configured to allow multiple folders to be stacked at a folder location during the slide sorting process. In these aspects, the apparatus is configured to determine number of folders stacked at each folder location.

Abstract: This invention relates to apparatus and methods for automated tissue sectioning, including slicing and transferring a tissue section from a microtome. The invention also relates to automated systems and methods for slicing and transferring a tissue section onto a slide.

Abstract: A nuclear magnetic resonance (NMR) system and method for determining oil and water composition in drilling mud by separating out signals from oil and water in a two dimensional relaxation space wherein the oil and water ratio is a function of the separated out signals. The spin-lattice relaxation time distribution or a spin-spin relaxation time distribution of the sample is measured and a spin-lattice versus spin-spin or a spin-spin versus diffusion two-dimensional procedure is applied to separate the components of the drilling fluid. The signal intensities from the oil and water regions of the one-dimensional or two-dimensional NMR measurements are used to quantify the relative portion of the proton NMR signal from the oil and water and to determine the ratio of oil and water in the drilling mud.

Abstract: Methods, devices and systems for identifying or authenticating an intact bottle of wine are provided.

Abstract: A mechanism by which rule attributes of varying types and numbers can be stored and searched in an efficient manner is provided by storing attribute values of each rule in a child table of a parent rule table. The child table is normalized and contains a foreign key pointing back to the parent rule table and has attribute-value pairs as table columns of the child table. Each rule is then represented by one row of the parent rule table and one or more corresponding rows of the child rule details table. A variable and unlimited number of attribute dimensions is supported among the rules, and search performance is improved through the use of database indexes on the rule details table attribute columns. Metadata representing the structure of the child rule details table will identify the data attributes for each dimension.

Abstract: This invention relates to methods and devices for NMR spectroscopy analyzing sealed containers e.g., food and beverage containers and other containers, and particularly according to specific embodiments sealed containers made of a conducting but generally nonferromagnetic metal or other conducting material. As discussed in above referenced applications, many current strategies for contaminant detection require a container to be violated, a process that can destroy the container or product and is impractical in large scale applications. The present invention overcomes these and other problems by providing methods and devices for the detection of contaminants and/or contraband in metal or conducting containers by NMR spectroscopy.

Abstract: A method of generating care areas is disclosed. An artwork file of a layout of a product is provided and a cell tree of the layout is formed. The cell tree includes a plurality of cells of the layout arranged in a hierarchical order. The method also includes defining care areas in the artwork file of the layout.

Abstract: Methods, device and systems for identifying or fingerprinting an intact bottle of wine are provided. Such methods are useful in authenticating a bottle of wine.

Abstract: An integrated circuit and e-beam testing method are disclosed. The integrated circuit includes a test structure with a ground grid, a metal pad having a space therein and positioned within the ground grid, and a metal line connected to the ground grid and positioned in the space. Structures for detecting open circuits and short circuits are described.