Patents by Inventor William J. Brown

William J. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7869663
    Abstract: Methods of analyzing three dimensional data sets obtained from a sample over time are provided. A first three dimensional data set is obtained from the sample at a first time. A first volume intensity projection (VIP) image is created from the first three dimensional data set. One or more first landmarks are identified and registered in the first VIP image. A second three dimensional data set is obtained from the sample at a second time, different from the first time. A second VIP image is created from the second three dimensional data set. The one ore more first landmarks are identified and registered in the second VIP image. The first and second VIP images are aligned based on the registered one or more first landmarks in the first and second VIP images. Related systems and computer program products are also provided.
    Type: Grant
    Filed: July 31, 2006
    Date of Patent: January 11, 2011
    Assignee: Bioptigen, Inc.
    Inventors: Eric L. Buckland, William J. Brown, Joseph A. Izatt
  • Patent number: 7847951
    Abstract: Some embodiments of the present invention provide optical coherence tomography systems including an OCT engine and a processor. The OCT engine is configured to provide both standard OCT imaging and spectral domain phase microscopy (SDPM) imaging. The processor is coupled to the OCT engine and is configured to use a first signal processing method when the OCT engine is configured to provide standard OCT imaging and a second signal processing method when the OCT engine is configured to provide SDPM imaging. Related methods and computer program products are also provided.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: December 7, 2010
    Assignee: Bioptigen, Inc.
    Inventors: Eric L. Buckland, Seungbum Woo, Joseph A. Izatt, William J. Brown
  • Publication number: 20100225925
    Abstract: Methods, systems and computer program products for generating parameters for software dispersion compensation in optical coherence tomography (OCT) systems are provided. Raw spectral interferogram data is acquired for a given lateral position on a sample and a given reference reflection. A trial spectral phase corresponding to each wavenumber sample of the acquired spectral interferogram data is postulated. The acquired raw spectral data and the postulated trial spectral phase data are assembled into trial complex spectrum data. Trial A-scan data is computed by performing an inverse Fourier transform on the trial complex spectrum data and determining the magnitude of a result.
    Type: Application
    Filed: May 17, 2010
    Publication date: September 9, 2010
    Inventors: Joseph A. Izatt, Eric L. Buckland, William J. Brown
  • Publication number: 20100180754
    Abstract: A portable device is disclosed for use with an audio or video content provider to establish hands-free control of the available functions of the content provider. The device may include a microphone interface to receive an electric signal from an integral or an externally plugged in microphone which, through use of a processor, may permit digitization of the signals, and comparison to a template of digital signals representing known voice commands that may be transmitted to the content provider. Non-volatile memory utilized in conjunction with the processor enables extended customization capabilities which are retained for later use, even after the device has been powered off. Operation of the device may alternatively occur according to default factory settings, or user programmed custom settings. Customizable features may include user trained voice commands, volume settings, sound effects, voice recognition thresholds, tone settings, and album lists.
    Type: Application
    Filed: January 22, 2009
    Publication date: July 22, 2010
    Inventors: William J. Brown, Len Novara, Christopher Wanless, Christopher Griswold
  • Patent number: 7719692
    Abstract: Methods, systems and computer program products for generating parameters for software dispersion compensation in optical coherence tomography (OCT) systems are provided. Raw spectral interferogram data is acquired for a given lateral position on a sample and a given reference reflection. A trial spectral phase corresponding to each wavenumber sample of the acquired spectral interferogram data is postulated. The acquired raw spectral data and the postulated trial spectral phase data are assembled into trial complex spectrum data. Trial A-scan data is computed by performing an inverse Fourier transform on the trial complex spectrum data and determining the magnitude of a result.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: May 18, 2010
    Assignee: Bioptigen, Inc.
    Inventors: Joseph A. Izatt, Eric L. Buckland, William J. Brown
  • Patent number: 7706553
    Abstract: A voice-activated, or voice-operated, remote control is adapted to reduce or eliminate the sound output of one or more entertainment appliances in order quiet the environment and thereby improve the effectiveness and accuracy its voice recognition functions. In one aspect of the present invention, the remote control sends a mute command to an appliance under control and listens for a voice command during an ensuing predetermined time period. In a further aspect of the present invention, the remote control determines which one of a plurality of unmute sequences is to be transmitted.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: April 27, 2010
    Assignee: Innotech Systems, Inc.
    Inventor: William J. Brown
  • Publication number: 20090316160
    Abstract: Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.
    Type: Application
    Filed: September 1, 2009
    Publication date: December 24, 2009
    Inventors: Joseph A. Izatt, Eric L. Buckland, William J. Brown
  • Patent number: 7616109
    Abstract: A system and method is provided for indicating a masking event using transmission wiring delegated for indicating intrusion and tampering events. The method of indicating a masking event utilizes measurable changes in resistance to indicate the current masking state of a detector. When a detector is not masked, a first resistance value is measurable on the transmission wiring, while when a detector is masked, a second resistance value is measurable on the transmission wiring. The transmission wiring connects the detector to a control unit that executes a security-related response based on the value of the measured resistance.
    Type: Grant
    Filed: March 9, 2006
    Date of Patent: November 10, 2009
    Assignee: Honeywell International Inc.
    Inventors: Colin S. McCulloch, Donna A. Mill, William J. Brown
  • Patent number: 7602500
    Abstract: Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: October 13, 2009
    Assignee: Bioptigen, Inc.
    Inventors: Joseph A. Izatt, Eric L. Buckland, William J. Brown
  • Publication number: 20090237673
    Abstract: Some embodiments of the present invention provide optical coherence tomography systems including an OCT engine and a processor. The OCT engine is configured to provide both standard OCT imaging and spectral domain phase microscopy (SDPM) imaging. The processor is coupled to the OCT engine and is configured to use a first signal processing method when the OCT engine is configured to provide standard OCT imaging and a second signal processing method when the OCT engine is configured to provide SDPM imaging. Related methods and computer program products are also provided.
    Type: Application
    Filed: June 4, 2009
    Publication date: September 24, 2009
    Inventors: Eric L. Buckland, Seungbum Woo, Joseph A. Izatt, William J. Brown
  • Publication number: 20090177094
    Abstract: Procedures, techniques, and systems for in vivo monitoring, diagnosis, and treatment of tissue during the same or concomitant medical procedure. In disclosed embodiments, during a same or concomitant procedure or examination, tissue can be scanned on a localized level using a real-time optical biopsy system. The real-time optical biopsy system may involve angle-resolved and/or Fourier domain low coherence interferometry (LCI). Because the scanning can be performed in real-time, diagnosis can also be performed in real-time and during the same or concomitant medical procedure. As a result, therapy, if needed, can also be administered to the tissue during the same or concomitant medical procedure. Monitoring of the tissue after therapy can be performed during the same or subsequent procedure.
    Type: Application
    Filed: January 8, 2009
    Publication date: July 9, 2009
    Applicant: Oncoscope, Inc.
    Inventors: William J. Brown, Adam Wax
  • Patent number: 7554669
    Abstract: Some embodiments of the present invention provide optical coherence tomography systems including an OCT engine and a processor. The OCT engine is configured to provide both standard OCT imaging and spectral domain phase microscopy (SDPM) imaging. The processor is coupled to the OCT engine and is configured to use a first signal processing method when the OCT engine is configured to provide standard OCT imaging and a second signal processing method when the OCT engine is configured to provide SDPM imaging. Related methods and computer program products are also provided.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: June 30, 2009
    Assignee: Bioptigen, Inc.
    Inventors: Eric L. Buckland, Seungbum Woo, Joseph A. Izatt, William J. Brown
  • Patent number: 7545504
    Abstract: Optical imaging systems are provided including a light source and a depolarizer. The light source is provided in a source arm of the optical imaging system. A depolarizer is coupled to the light source in the source arm of the optical imaging system and is configured to substantially depolarize the light from the light source. Related methods and controllers are also provided.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: June 9, 2009
    Assignee: Biotigen, Inc.
    Inventors: Eric L. Buckland, John R. Marciante, Joseph A. Izatt, William J. Brown
  • Publication number: 20090073456
    Abstract: Embodiments described herein involve low-coherence interferometry (LCI) techniques which enable acquisition of structural and depth information regarding a sample of interest. In one embodiment, a “swept-source” (SS) light source is used in LCI to obtain structural and depth information about a sample. The swept-source light source can be used to generate a reference signal and a signal directed towards a sample. Light scattered from the sample is returned as a result and mixed with the reference signal to achieve interference and thus provide structural information regarding the sample. Depth information about the sample can be obtained using Fourier domain concepts as well as time domain techniques. Several LCI embodiments employing a swept-source light source are disclosed herein. In another embodiment disclosed herein, an a/LCI system and method is provided that is based on a time domain system and employs a broadband light source.
    Type: Application
    Filed: September 15, 2008
    Publication date: March 19, 2009
    Applicant: DUKE UNIVERSITY
    Inventors: Adam Wax, William J. Brown
  • Publication number: 20090018888
    Abstract: A lead marketplace system and method are provided. The lead marketplace system and method provides an auction for leads.
    Type: Application
    Filed: April 2, 2008
    Publication date: January 15, 2009
    Applicant: Reply! Inc.
    Inventors: Payam Zamani, William J. Brown, Ernest Rodrigues, JR.
  • Patent number: 7295831
    Abstract: A method and system for wireless intrusion detection, prevention and security management. The method and system provides autonomous wireless intrusion detection and prevention, with minimal or no operator intervention. The method and system integrates a physical layer (e.g., OSI layer 1) a smart wireless radio frequency (RF) antenna subsystem with a data-link layer (e.g., OSI layer 2) wireless security system management platform.
    Type: Grant
    Filed: February 7, 2004
    Date of Patent: November 13, 2007
    Assignee: 3E Technologies International, Inc.
    Inventors: Ryon K. Coleman, John M. Fossaceca, William J. Brown
  • Patent number: 7145450
    Abstract: In this compactor service and monitoring system, compactor fullness and other critical parameters are monitored by an on-site processor. Compactor fullness is monitored using a pressure sensor capable of measuring hydraulic fluid system pressure for a compactor ram during a compactor compaction cycle. The processor generates a message indicating the compactor is full when the pressure is at least equal to a preset pressure for a preset time during a compaction cycle. Messages are sent via a wireless transmitter to a receiver that converts these messages into internet messages and directs them to a computer server database system. This system creates a work order in response to the message and sends the work order to a service provider via email. The email contains a link back to the database system web-site for tracking services provided by the recipient.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: December 5, 2006
    Inventor: William J. Brown
  • Patent number: 6922529
    Abstract: Devices, such as node and network elements for use in communications systems, which include a plurality of ports, each having an input and an output, a plurality of splitters corresponding to the port inputs, a plurality of combiners corresponding to the port outputs, a plurality of signal paths between the splitters and the combiners, wherein each of the signal paths includes a signal varying device, and a plurality of protection devices connected between the splitters and the combiners, wherein each of the plurality of protection devices includes a signal varying device and provides a protection path corresponding to a plurality of the signal paths, and wherein at least one splitter has at least one unused output after the signal paths and the protection paths are connected, and wherein at least one combiner has at least one unused input after the signal paths and the protection paths are connected.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: July 26, 2005
    Assignee: Corvis Corporation
    Inventors: Michael L. Bortz, William J. Brown
  • Patent number: 6879351
    Abstract: Methods and apparatus to facilitate communication between a user and one or more devices which are remote from the user, reduce the number of required button presses and further reduce keystroke errors, by including the functionality to associate a user selected default device with a particular set of buttons. A universal remote control unit suitable for use with various audio/visual entertainment devices may embody various aspects of the present invention.
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: April 12, 2005
    Assignee: Innotech Systems, Inc.
    Inventor: William J. Brown
  • Patent number: 6802138
    Abstract: A footwear cushioning system including an insole platform and an insert that cooperate with one another. The insole platform includes a recess defined in the heel and/or forefoot area. The insert includes a footbed and heel and/or forefoot cushion extending from the footbed. The cushions interfit with the respective heel and/or forefoot recess of the insole platform. In a preferred embodiment, the insole platform includes a shank secured thereto, surrounding the heel recess. The insole platform is preferably shaped to define both heel and forefoot recesses and the insert includes cushions that interfit with both recesses. A midsole is secured to the insole platform and an outsole is further secured to the midsole. To assemble the cushion system, the insole platform is secured to the upper. The midsole is then secured to the insole platform. The outsole is adhered to the under surface of the midsole.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: October 12, 2004
    Assignee: Wolverine World Wide, Inc.
    Inventors: Ronald P. McManus, William J. Brown, Gary L. Sikes