Patents by Inventor William J. Harrison
William J. Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230173254Abstract: A catheter pump includes an elongate cannula with a formed mesh structure extending cylindrically between opposing ends thereof. The formed mesh structure defines a pattern configured to be stably expandable and collapsible without fracturing in a percutaneous delivery and re-sheathing in the provision of mechanical circulatory support of a patient’s heart.Type: ApplicationFiled: January 13, 2023Publication date: June 8, 2023Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Patent number: 11660441Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: GrantFiled: October 31, 2020Date of Patent: May 30, 2023Assignee: TC1 LLCInventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Patent number: 11654276Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: GrantFiled: October 31, 2020Date of Patent: May 23, 2023Assignee: TC1 LLCInventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20230076777Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: ApplicationFiled: November 10, 2022Publication date: March 9, 2023Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20220241098Abstract: An intravascular implant can include a pair of inner rings comprising a distal inner ring and a proximal inner ring. A plurality of inner bridges can extend between opposing adjacent apices of the distal and proximal inner rings. Each of the plurality of inner bridges can form an eyelet. The implant can include a pair of outer rings comprising a distal outer ring and a proximal outer ring. The distal and proximal outer rings that can each be formed by a plurality of struts connected by apices formed in a zig-zag pattern. A plurality of outer bridge members can include a plurality of outer bridge members that extend between opposing adjacent apices of the distal outer ring and distal inner ring and outer bridge members that extend between opposing adjacent apices of the proximal outer ring and proximal inner ring.Type: ApplicationFiled: April 22, 2020Publication date: August 4, 2022Inventors: William J. HARRISON, Daniel P. ALEXANDER, Michael A. LONGO, Payman SAFFARI, Chad J. SMITH
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Patent number: 11058865Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: GrantFiled: August 23, 2018Date of Patent: July 13, 2021Assignee: TC1 LLCInventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20210046229Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: ApplicationFiled: October 31, 2020Publication date: February 18, 2021Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20210046230Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: ApplicationFiled: October 31, 2020Publication date: February 18, 2021Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20180361042Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: ApplicationFiled: August 23, 2018Publication date: December 20, 2018Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Patent number: 10086121Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: GrantFiled: June 3, 2016Date of Patent: October 2, 2018Assignee: TC1 LLCInventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20160279309Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: ApplicationFiled: June 3, 2016Publication date: September 29, 2016Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Patent number: 9358329Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: GrantFiled: March 13, 2013Date of Patent: June 7, 2016Assignee: THORATEC CORPORATIONInventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Patent number: 8906354Abstract: The present invention relates to a loaded particle comprising at least one fluorescent dye, and in particular, a fluorescent dye with a large Stokes shift. The invention further relates to a method for producing an loaded latex particle, loaded with a fluorescent dye having a large stokes shift. In addition, the present invention relates to latex particles loaded with fluorescent dyes that are organic solvent soluble and insoluble in water. In a preferred embodiment, when the dyes are loaded into the water soluble latex particle, an increase is observed in quantum yield of fluorescence as compared to the quantum yield of the dye in aqueous solvent.Type: GrantFiled: March 8, 2011Date of Patent: December 9, 2014Assignee: Bruker Biospin CorporationInventors: Tao Ji, Hans F. Schmitthenner, Yonghong Yang, John W. Harder, Jeffrey W. Leon, William J. Harrison, Brian J. Kelley, James R. Bennett, David A. Stegman, Ruizheng Wang
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Publication number: 20140012065Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: ApplicationFiled: March 13, 2013Publication date: January 9, 2014Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20120058050Abstract: The present invention relates to a loaded particle comprising at least one fluorescent dye, and in particular, a fluorescent dye with a large Stokes shift. The invention further relates to a method for producing an loaded latex particle, loaded with a fluorescent dye having a large stokes shift. In addition, the present invention relates to latex particles loaded with fluorescent dyes that are organic solvent soluble and insoluble in water. In a preferred embodiment, when the dyes are loaded into the water soluble latex particle, an increase is observed in quantum yield of fluorescence as compared to the quantum yield of the dye in aqueous solvent.Type: ApplicationFiled: March 8, 2011Publication date: March 8, 2012Inventors: Tao Ji, Hans F. Schmitthenner, Yonghong Yang, John W. Harder, Jeffrey W. Leon, William J. Harrison, Brian J. Kelley, James R. Bennett, David A. Stegman, Ruizheng Wang
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Patent number: 8057529Abstract: A stent delivery system for implantation of a stent in a vessel includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent. The proximal end of the outer tubular member is attached to a pull-back handle which is slidably mounted on the base of the housing assembly. When the pull-back handle is retracted, the restraining sheath is retracted to deploy the sheath, while the inner tubular member remains stationary.Type: GrantFiled: September 25, 2008Date of Patent: November 15, 2011Assignee: Abbott Cardiovascular Systems Inc.Inventors: Daniel L. Cox, Mathew J. Fitz, William J. Harrison, Michael D. Schultz, Josepher A. Ventura
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Patent number: 8017104Abstract: The present invention relates to a diagnostic contrast agent comprising a water dispersible, near-infrared tricarbocyanine, enamine-functionalized dye having a Stoke shift of greater than 50 and represented by five general formulae. The present invention also relates to a method for making a dye-conjugate utilizing the novel dye and a method of identifying a biological compound using the novel dye conjugate.Type: GrantFiled: February 28, 2007Date of Patent: September 13, 2011Assignee: Carestream Health, Inc.Inventors: Ruizheng Wang, John W. Harder, David A. Stegman, William J. Harrison, Hans F. Schmitthenner
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Patent number: 7976560Abstract: An expandable frame for an embolic filtering device used to capture embolic debris in a body vessel includes a first half frame having a first control arm connected to a second control arm by a partial loop and a second half frame having a first control arm connected to a second control arm by a partial loop. The partial loops cooperatively form a composite loop for attachment of a filtering element which will expand in the body vessel to capture embolic debris entrained in the fluid of the vessel. The lengths and positioning of the first and second control arms of each half frame can be varied to create an expandable frame which conforms to the size and shape of the body vessel in which the filtering device is deployed. Additionally, the radius of the partial loops, along with the length of the arc of the partial loops, can be varied on each of the frames to create a composite filtering assembly that can easily adapt to the size and shape of the body vessel.Type: GrantFiled: January 17, 2007Date of Patent: July 12, 2011Assignee: Abbott Cardiovascular Systems Inc.Inventors: Andy E. Denison, William J. Harrison, Benjamin C. Huter, Scott J. Huter, John E. Papp, Steven T. Saville, Kent C. B. Stalker
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Publication number: 20090284829Abstract: A surface plasmon element comprising an array of metal nanoparticles (1) with an adsorbed layer of resonant material and the use of such material to activate said array.Type: ApplicationFiled: August 31, 2007Publication date: November 19, 2009Inventors: Christopher L. Bower, William J. Harrison, Anatoly V. Zayats, Robert J. Pollard, Gregory A. Wurtz, Paul Evans
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Publication number: 20090169482Abstract: A nanoparticulate imaging probe with an oxide core, a biocompatible polymeric shell covalently attached to the oxide core, a dye, and a cleavable spacer that covalently binds the dye to the probe. When the spacer is cleaved, the dye is liberated from the probe. The emissions of the dye are quenched when the dye is bound to the probe and not quenched when the dye is liberated from the probe. The spacer can be, for example, a peptide. The oxide core can be, for example, a silicon oxide core.Type: ApplicationFiled: October 31, 2007Publication date: July 2, 2009Inventors: Shiying Zheng, Lijun Dai, Ruizheng Wang, Tiecheng A. Qiao, Wenyi Che, William J. Harrison