Patents by Inventor Wolf Bertling

Wolf Bertling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7396557
    Abstract: The invention relates to a method for forgery-proof labeling of items, such as credit cards, bank notes and the like, comprising the following steps: (a) applying, to a first layer (1) that reflects electromagnetic waves, an inert second layer (3) that is permeable to electromagnetic waves, said second layer having a predetermined thickness, (b) applying, to said second layer (3), a third layer (4) that is formed by metal clusters, and (c) linking the first layer (1) of the label so produced with the item.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: July 8, 2008
    Assignee: november Aktiengesellschaft Gesellschaft fur Molekulare Medizin
    Inventors: Georg Bauer, Jörg Hassmann, Harald Walter, Wolf Bertling
  • Publication number: 20080009013
    Abstract: The invention relates to a method for identifying a first polymer sequence bound to a first phase that reflects electromagnetic waves. The inventive method includes the following steps: a) bringing the first polymer sequence into contact with an affine second polymer sequence, which is directly or indirectly bound, via metallic clusters, to a solid second phase that is permeable to electromagnetic waves; b) radiating electromagnetic waves through the second phase, and; c) detecting the alteration of the properties of the reflected electromagnetic waves.
    Type: Application
    Filed: September 21, 2007
    Publication date: January 10, 2008
    Inventors: Wolf Bertling, Jorg Hassmann, Harald Walter, Thomas Schalkhammer, Georg Bauer
  • Patent number: 7303884
    Abstract: The invention relates to a method for indirectly determining the blood-clotting status.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: December 4, 2007
    Assignee: november Aktiengesellschaft Gesellschaft für Molekulare Medizin
    Inventor: Wolf Bertling
  • Publication number: 20070009921
    Abstract: The invention relates to a synthetic, biologically active molecule for fixing an active ingredient to the virus protein 1 (VP1) of the polyoma virus. According to the invention, an amino acid sequence A1 which is derived from the C-terminal end of virus protein 2 (VP2) or 3 (VP3) of the polyoma virus is bonded to an active ingredient at one of its ends.
    Type: Application
    Filed: December 22, 2005
    Publication date: January 11, 2007
    Inventors: Jurgen Walter, Christian Reiser, Wolf Bertling
  • Publication number: 20060293226
    Abstract: The invention relates to a medicament for tumor therapy, containing a first and a second molecule in an effective concentration, the first molecule representing a1) Annexin V or a molecule that is largely similar thereto, or a2) an effective fragment of Annexin V or the molecule that is largely similar thereto, and the second molecule representing b1) a cytokine or a molecule that is largely similar thereto, or b2) an effective fragment of a cytokine or the molecule that is largely similar thereto.
    Type: Application
    Filed: January 19, 2004
    Publication date: December 28, 2006
    Inventor: Wolf Bertling
  • Publication number: 20060201886
    Abstract: The invention relates to a method for determining the binding behavior of ligands which specifically bind to target molecules at at least one binding site, whereby the markers are present in a native form and the determination of the concentrations K4 and K5 or of the quantities M2 and M1 is carried out by means of mass spectrometry.
    Type: Application
    Filed: May 19, 2006
    Publication date: September 14, 2006
    Inventors: Klaus Wanner, Georg Hofner, Wolf Bertling
  • Patent number: 7074334
    Abstract: The invention relates to a method for determining the binding behavior of ligands which specifically bind to target molecules at at least one binding site, whereby the markers are present in a native form and the determination of the concentrations K4 and K5 or of the quantities M2 and M1 is carried out by means of mass spectrometry.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: July 11, 2006
    Inventors: Klaus Wanner, Georg Höfner, Wolf Bertling
  • Patent number: 7067253
    Abstract: The invention relates to a method for identifying a first polymer (4, 7) which is bonded to a first phase (5) that reflects electromagnetic waves. Said method comprises the following steps: (a) bringing the first polymer (4, 7) into contact with a second polymer (3, 8), which is bonded to a solid second phase (1) by metallic clusters (2), said second phase being permeable to electromagnetic waves; (b) irradiating the second phase (1) with electromagnetic waves; and (c) determining the change in the properties of the reflected electromagnetic waves.
    Type: Grant
    Filed: June 10, 2000
    Date of Patent: June 27, 2006
    Assignee: november Aktiengesellschaft Gesellschaft für Molekulare Medizin
    Inventors: Wolf Bertling, Jorg Hassmann
  • Patent number: 7011968
    Abstract: The invention relates to a synthetic, biologically active molecule for fixing an active ingredient to the virus protein 1 (VP1) of the polyoma virus. According to the invention, an amino acid sequence A1 which is derived from the C-terminal end of virus protein 2 (VP2) or 3 (VP3) of the polyoma virus is bonded to an active ingredient at one of its ends.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: March 14, 2006
    Assignee: november Aktiengesellschaft Gesellschaft fur Molekulare Medizin
    Inventors: Jurgen Walter, Christian Reiser, Wolf Bertling
  • Publication number: 20050059587
    Abstract: The invention relates to the use of a protein for producing a medicament for stimulating an innate non specific immune system, wherein the protein contains a) an annexine V or a largely similar molecule thereto or b) an active fragment of annexine V or a largely similar molecule thereto.
    Type: Application
    Filed: August 24, 2002
    Publication date: March 17, 2005
    Inventors: Martin Herrmann, Wolf Bertling, Joachim Kalden, Reinhard Voll, Angelo Manfredi, Wasilis Kolowos, Christian Reiser, Walter Woith
  • Publication number: 20050043413
    Abstract: An active ingredient for producing a medicament for inhibiting the coagulation of blood, and a corresponding medicament are provided. The active ingredient is isocitrate or an active derivative thereof.
    Type: Application
    Filed: August 16, 2004
    Publication date: February 24, 2005
    Inventors: Wolf Bertling, Mats Ranby
  • Publication number: 20040232077
    Abstract: The invention relates to a method for determining the binding behavior of ligands which specifically bind to target molecules at at least one binding site, whereby the markers are present in a native form and the determination of the concentrations K4 and K5 or of the quantities M2 and M1 is carried out by means of mass spectrometry.
    Type: Application
    Filed: November 15, 2003
    Publication date: November 25, 2004
    Inventors: Klaus Wanner, Georg Hofner, Wolf Bertling
  • Patent number: 6803021
    Abstract: The invention relates to a device for receiving and discharging a given amount of liquid, comprising agitating means (2) arranged on one end (E1) of a capillary (1) and a diaphragm (3) in the vicinity of the other end (E2).
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: October 12, 2004
    Assignee: November AG Novus Medicatus Bertling Gesellschaft fur Molekulare Medizin
    Inventor: Wolf Bertling
  • Publication number: 20040091877
    Abstract: The invention relates to a method for identifying a first polymer sequence bound to a first phase that reflects electromagnetic waves. The inventive method includes the following steps: a) bringing the first polymer sequence into contact with an affine second polymer sequence, which is directly or indirectly bound, via metallic clusters, to a solid second phase that is permeable to electromagnetic waves; b) radiating electromagnetic waves through the second phase, and; c) detecting the alteration of the properties of the reflected electromagnetic waves.
    Type: Application
    Filed: June 13, 2003
    Publication date: May 13, 2004
    Inventors: Wolf Bertling, J?ouml;rg Hassmann, Harald Walter, Thomas Schalkhammer, Georg Bauer
  • Patent number: 6696021
    Abstract: The invention relates to a device for analyzing biological or medical specimens, such as nucleic acids, tissue and the like, in which a closure element is provided for the leaktight closure of a preparation chamber formed in a basic body, the preparation chamber being connected to at least one first duct, through which substance can be introduced into and removed from the preparation chamber when the closure element is closed.
    Type: Grant
    Filed: January 25, 1999
    Date of Patent: February 24, 2004
    Inventor: Wolf Bertling
  • Publication number: 20040026917
    Abstract: The invention relates to a method for forgery-proof labeling of items, such as credit cards, bank notes and the like, comprising the following steps: (a) applying, to a first layer (1) that reflects electromagnetic waves, an inert second layer (3) that is permeable to electromagnetic waves, said second layer having a predetermined thickness, (b) applying, to said second layer (3), a third layer (4) that is formed by metal clusters, and (c) linking the first layer (1) of the label so produced with the item.
    Type: Application
    Filed: June 4, 2003
    Publication date: February 12, 2004
    Inventors: Georg Bauer, Jorg Hassmann, Harald Walter, Wolf Bertling
  • Publication number: 20040013872
    Abstract: The invention relates to a synthetic particle used for marking a substance. Said synthetic particle is comprised of a number of identification substances (10, 12), which exist in a solid form, and of at least one covering (16), which encloses at least one of the identification substances (10, 12). The identification substances (10, 12) are selected such that the synthetic particle (18) can be identified by simultaneously identifying the identification substances (10, 12) in one and the same identification method on the basis of non-optical properties of the identification substances (10, 12).
    Type: Application
    Filed: July 14, 2003
    Publication date: January 22, 2004
    Inventors: Wolf Bertling, Hans Kosak
  • Publication number: 20030186257
    Abstract: The invention relates to a method for identify a predetermined mark (32) applied on a solid body (30) and constituted by planar elements (10). The inventive method comprises the following steps: (a) binding first biopolymers to a first part of the planar elements (10) so as to produce a first predetermined partial pattern, (b) contacting the mark (32) with third biopolymers that have an affinity to the first biopolymers so that the first and the third biopolymers bind to one another, and (c) identifying the first partial pattern produced by the bound first and third biopolymers by detecting the bond between the first and the third bipolymers by means of a one-stop detection method.
    Type: Application
    Filed: November 12, 2002
    Publication date: October 2, 2003
    Inventors: Wolf Bertling, Hans Kosak, Andr?eacute; Josten, Georg Bauer, Harald Walter
  • Patent number: 6620612
    Abstract: The invention relates to a device for conducting biochemical and microbiological reactions, comprising a support (2) for receiving at least one reaction vessel (3) and a device (5) for pressing a closing means (11, 12) sealing the reaction vessel (3), wherein the closing means (11, 12) project in closed position in the area surrounded by the reaction vessel (3). According to the invention, in order to accelerate and simplify reaction, an inner wall of the closing means opposite the reaction vessel (3) is coated with a molecule (14) on which a molecule to be detected can be bonded or deposited, wherein the molecule (14) contains a nucleic acid, an amino acid or a synthetic derivative of a nucleic or amino acid.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: September 16, 2003
    Assignee: November Aktiengesellschaft Gesellschaft fur Molekulare Medizin
    Inventor: Wolf Bertling
  • Patent number: 6540762
    Abstract: A method for perforating skin including a lancet (1) held in a lancet holder (2) which, by means of a spring-loaded element (9), can be locked in a housing and moved out of the housing. To improve hygiene the invention provides for the lancet holder to be housed in a cup (5), which can be attached to the housing (8), and slidably guided in the cup.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: April 1, 2003
    Assignee: November Aktiengesellschaft Gesellschaft fur Molekulare Medizin
    Inventor: Wolf Bertling