Abstract: A method for isolating proteins from prokaryotes is disclose. The method enables easy break down of bacterial cell walls to obtain intact proteins without damage by a simple process of adding organic solvents including lower alcohols or nitrile derivatives; or applying osmotic stimulation to samples containing pathogenic bacteria or the like. The method may be usefully applied to rapid and accurate identification of periplasmic proteins of gram-negative bacteria without additional purification process.

Abstract: Computerized systems and methods for managing API information. An exemplary method includes receiving an input from a user device associated with a first computer system, the input not including identity of a second computer system. The method includes determining a target API based on the input, the target API being the second computer system's API. The method also includes determining whether a user of the user device has access to the target API. The method includes retrieving documentation of the target API from an API database if it is determined that the user has access to the target API. The method includes providing the user device with the retrieved documentation.

Abstract: The present invention relates to a method for detecting a pathogenic strain having resistance to carbapenem antibiotics in a biological sample. According to the present invention, it is possible to directly identify carbapenemases, specifically KPC, OXA, NDM, IMP, VIM and/or GES protein, by mass spectrometry, thereby making it possible to quickly determine not only whether a pathogenic strain has resistance to antibiotics, but also the type of protein involved in the resistance. According to the present invention, the physical and chemical properties of each carbapenemase in vivo, such as the unique N-terminal truncation length, methionine residue oxidation and disulfide bond formation in each type of carbapenemase, are identified and are reflected on reference mass values.

Abstract: A method of treating or preventing pruritus in a subject in need thereof using a pharmaceutical composition is provided. The method includes administering a therapeutically effective amount of T?4, T?4 fragments, T?4 isoforms, T?4 derivatives, or variants thereof, wherein the therapeutically effective amount decreases release of a pruritus-related factor or decreases release of an inflammatory cytokine from a target tissue is provided.

Abstract: The present invention relates to a method for detecting a pathogenic strain having resistance to ?-lactam antibiotics in a biological sample, and a method for identifying a protein involved in resistance in ?-lactam antibiotics, which is contained in a biological sample. According to the present invention, it is possible to quickly and accurately determine not only whether a pathogenic strain has resistance to antibiotics, but also the type of protein involved in the resistance, by directly identifying an extended spectrum ?-lactamase (ESBL) protein with a truncated N-terminus through mass spectrometry. Accordingly, the present invention can be effectively utilized to quickly establish an appropriate antibiotic administration strategy at the initial stage of infection.

Abstract: Computerized systems and methods for managing API information. An exemplary method includes receiving an input from a user device associated with a first computer system, the input not including identity of a second computer system. The method includes determining a target API based on the input, the target API being the second computer system's API. The method also includes determining whether a user of the user device has access to the target API. The method includes retrieving documentation of the target API from an API database if it is determined that the user has access to the target API. The method includes providing the user device with the retrieved documentation.

Abstract: Methods of treating dry eye syndrome (DES) with an effective amount of thymosin beta 4 (T?4), T?4 fragments, T?4 isoforms, T?4 derivatives, peptide agents including amino acid sequence LKKTET [SEQ ID NO:1] or LKKTNT [SEQ ID NO:2], or variants thereof are provided. The presently disclosed subject matter provides methods of increasing tear volume, increasing tear film stability, decreasing ocular surface damage, and decreasing ocular discomfort by delivering compositions of thymosin beta 4 or fragments thereof to subjects in need.

Abstract: Methods of treating dry eye syndrome (DES) with an effective amount of thymosin beta 4 (T?4), T?4 fragments, T?4 isoforms, T?4 derivatives, peptide agents including amino acid sequence LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO:2], or variants thereof are provided. The presently disclosed subject matter provides methods of increasing tear volume, increasing tear film stability, decreasing ocular surface damage, and decreasing ocular discomfort by delivering compositions of thymosin beta 4 or fragments thereof to subjects in need.

Abstract: Computerized systems and methods for managing API information. An exemplary method includes receiving an input from a user device associated with a first computer system, the input not including identity of a second computer system. The method includes determining a target API based on the input, the target API being the second computer system's API. The method also includes determining whether a user of the user device has access to the target API. The method includes retrieving documentation of the target API from an API database if it is determined that the user has access to the target API. The method includes providing the user device with the retrieved documentation.

Abstract: Computerized systems and methods for managing API information. An exemplary method includes receiving an input from a user device associated with a first computer system, the input not including identity of a second computer system. The method includes determining a target API based on the input, the target API being the second computer system's API. The method also includes determining whether a user of the user device has access to the target API. The method includes retrieving documentation of the target API from an API database if it is determined that the user has access to the target API. The method includes providing the user device with the retrieved documentation.

Abstract: A method for diagnosing follicular thyroid carcinoma is described. The method measures protein expression levels of an aminoacyl-tRNA synthetase (ARS) or an aminoacyl-tRNA synthetase complex-interacting multifunctional protein (AIMP) in a sample, such as a thyroid tissue sample, from a subject suspected of having follicular thyroid carcinoma. The protein expression levels of ARS or AIMP are compared to the measured protein expression levels in a control.

Abstract: Computerized systems and methods for managing API information. An exemplary method includes receiving an input from a user device associated with a first computer system, the input not including identity of a second computer system. The method includes determining a target API based on the input, the target API being the second computer system's API. The method also includes determining whether a user of the user device has access to the target API. The method includes retrieving documentation of the target API from an API database if it is determined that the user has access to the target API. The method includes providing the user device with the retrieved documentation.

Abstract: The present invention relates to a method for detecting markers for diagnosis of follicular thyroid carcinoma using an expression level of aminoacyl-tRNA synthetase-related protein. More specifically, the present invention relates to a method for detecting markers of follicular carcinoma in order to provide necessary for the diagnosis of follicular thyroid carcinoma in a patient suspected of having follicular thyroid carcinoma, the method comprising; (a) a step of providing a sample from a subject suspected of having follicular thyroid carcinoma; (b) a step of measuring the protein expression of an aminoacyl-tRNA synthetase or an aminoacyl-tRNA synthetase complex-interacting multifunctional protein in the sample; and (c) a step of comparing the measured protein expression level with that of a control, and determining that the subject having a confirmed change in the protein expression level has follicular thyroid carcinoma.

Abstract: Methods of treating dry eye syndrome (DES) with an effective amount of thymosin beta 4 (T?4), T?4 fragments, T?4 isoforms, T?4 derivatives, peptide agents including amino acid sequence LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO:2], or variants thereof are provided. The presently disclosed subject matter provides methods of increasing tear volume, increasing tear film stability, decreasing ocular surface damage, and decreasing ocular discomfort by delivering compositions of thymosin beta 4 or fragments thereof to subjects in need.

Abstract: Disclosed is a quickly soluble oral film dosage for masking a nasty taste, in particular, a quickly soluble oral film dosage comprising a stevioside based sweetener and a high potency sweetener in a ratio by weight (w/w) of 1:3 to 3:1, which may efficiently mask a bitter or nasty taste of a medicine and may be quickly dissolved in a mouth without water, thereby improving an aftertaste thereof thus enhancing dosage acceptability of a patient.

Abstract: An image management method and system are disclosed which can increase user convenience by reducing a display time of thumbnails in a DLNA system. The DLNA system includes a digital media server for generating a thumbnail group image using thumbnails corresponding to at least one original image file and transmitting the thumbnail group image, and a digital media player for receiving the thumbnail group image from the digital media server and requesting the digital media server to transmit an original image file corresponding to a selected thumbnail among thumbnails included the thumbnail group image.

Abstract: An apparatus and method provide advertising (Ad) ranking information. An Ad information collector collects Ad property information included in a plurality of advertisements. A feedback information collector collects feedback information that is determined as a function of Ad impressions. A table generator generates an Ad information collection table as a function of the Ad property information and the feedback information. A ranking calculator generates Ad ranking information for the plurality of advertisements using the generated Ad information collection table. Upon receiving an Ad request from an Ad exposure device, a processor requests the plurality of advertisements from a plurality of Ad networks, receives the requested plurality of advertisements from the plurality of Ad networks, receives the feedback information from the Ad exposure device, and transmits the generated Ad ranking information to the Ad exposure device along with the received plurality of advertisements.

Abstract: Disclosed is a quickly soluble oral film dosage for masking a nasty taste, in particular, a quickly soluble oral film dosage comprising a stevioside based sweetener and a high potency sweetener in a ratio by weight (w/w) of 1:3 to 3:1, which may efficiently mask a bitter or nasty taste of a medicine and may be quickly dissolved in a mouth without water, thereby improving an aftertaste thereof thus enhancing dosage acceptability of a patient.

Abstract: A music linked photocasting service system and method are provided. The music linked photocasting service method includes reproducing music at the request of a user, analyzing a mood of the reproduced music at prescribed times, until music reproduction is completed, searching photographs suitable for a analyzed mood of the music, and displaying the searched photographs.

Abstract: Disclosed is a quickly soluble oral film dosage for masking a nasty taste, in particular, a quickly soluble oral film dosage comprising a stevioside based sweetener and a high potency sweetener in a ratio by weight (w/w) of 1:3 to 3:1, which may efficiently mask a bitter or nasty taste of a medicine and may be quickly dissolved in a mouth without water, thereby improving an aftertaste thereof thus enhancing dosage acceptability of a patient.