Abstract: A cell death inhibitor including a mesenchymal stem cell genetically engineered to secrete growth-regulated oncogene-alpha (GRO-?) or overexpress GRO-? compared to a parent cell, GRO-?, or a combination thereof. A method of treating a muscle disease, including administering a pharmaceutically effective amount of a mesenchymal stem cell, which is genetically engineered to secrete growth-regulated oncogene-alpha (GRO-?) or overexpress GRO-? compared to a parent cell, or GRO-?, to a subject in need thereof.

Abstract: A hybrid air mobility system is capable of flying a long distance through effective operation of an engine and batteries. The hybrid air mobility system includes a fuselage configured to supply power to a propeller and electric equipment, the fuselage being provided with a duct including an inlet and an outlet so as to circulate air to the engine and the electric equipment; a deflector rotatably installed at the outlet of the duct so as to convert a discharge direction of exhaust gas generated by the engine and cooling air after cooling the electric equipment; and a controller configured to determine whether or not the engine is driven and to control a rotated position of the deflector depending on an amount of driving of the engine so as to selectively adjust movement of the exhaust gas and the cooling air towards the propeller.

Abstract: The present invention relates to a composition comprising or consisting of two or more bacteria strains, formulated for the prophylaxis or treatment of intestinal barrier dysfunction and/or heat stress in a subject. More particularly, the composition comprises two or more of Lactobacillus reuteri MM2-3, Lactobacillus plantarum WCSF1, Streptococcus thermophilus B of R and Escherichia coli Nissle 1917. The present invention also includes uses of the invention to treat conditions such as inflammatory bowel disease (IBD) and heat stress.

Abstract: The present disclosure provides a pump including a housing having a shaft hole, a membrane assembly disposed inside the housing, and a shaft assembly mounted on the housing. The shaft assembly includes a shaft inserted into the shaft hole, and a sealing member disposed on an end portion of the shaft and having a plurality of contact regions on an inner surface of the housing along a longitudinal direction of the shaft.

Abstract: A display device includes a base, a light emitting element disposed on the base, a capping layer disposed on the light emitting element, a thin-film encapsulation layer which is disposed on the capping layer and includes an inorganic layer at the bottom, and a wavelength conversion pattern which is disposed on the thin-film encapsulation layer and overlaps the light emitting element. The capping layer includes a first sub-capping layer disposed on the light emitting element and a second sub-capping layer disposed between the first sub-capping layer and the inorganic layer, and a refractive index of the second sub-capping layer is greater than a refractive index of the inorganic layer and smaller than a refractive index of the first sub-capping layer.

Abstract: A gate driver includes a plurality of gate stages. Each of the plurality of gate stages includes a carry generating circuit outputting a second carry signal having a phase which is later than a phase of a first carry signal, on the basis of a first clock signal and a second clock signal having different phases and a scan generating circuit outputting a scan signal having a phase which differs from phases of the first and second carry signals, on the basis of the first clock signal, the second clock signal, and the first carry signal. Each of the first clock signal, the second clock signal, the first carry signal, and the second carry signal may be a P-type pulse, and the scan signal may be an N-type pulse.

Abstract: A gate driver includes a plurality of gate stages. Each of the plurality of gate stages includes a carry generating circuit outputting a second carry signal having a phase which is later than a phase of a first carry signal, on the basis of a first clock signal and a second clock signal having different phases and a scan generating circuit outputting a scan signal having a phase which differs from phases of the first and second carry signals, on the basis of the first clock signal, the second clock signal, and the first carry signal. Each of the first clock signal, the second clock signal, the first carry signal, and the second carry signal may be a P-type pulse, and the scan signal may be an N-type pulse.

Abstract: The present disclosure provides a display device having a touch sensor for reducing the size of a bezel area. The display device having a touch sensor is configured such that touch electrodes and touch lines are disposed in a mesh shape on an encapsulation layer encapsulating light-emitting elements and such that some of the touch lines are connected to a touch-driving circuit via an upper bezel area, thereby reducing the size of left and right bezel areas.

Abstract: A method of culturing mesenchymal stem cells includes performing primary culture of umbilical cord-derived mesenchymal stem cells under hypoxic conditions with an oxygen partial pressure of 1 to 8% and pressure conditions of 1.0 to 8.0 PSI. The method of culturing umbilical cord-derived mesenchymal stem cells can maintain stemness by inhibiting the differentiation of stem cells and particularly can achieve a remarkably high proliferation rate.

Abstract: The present disclosure relates to a medium composition for enhancing proliferation of stem cells, comprising ethionamide, and a use thereof. It is possible, according to the present disclosure, to mass-produce highly-efficient next-generation stem cells through a simple and safe method of controlling a culturing environment, without using genetic modification or viral vectors, etc.

Abstract: Provided are a composition for ciliogenesis, containing a mesenchymal stem cell or a culture medium of mesenchymal stem cell. The mesenchymal stem cell or the culture medium of mesenchymal stem cell increases the number and promotes growth of primary cilia in cells. The mesenchymal stem cell or the culture medium of mesenchymal stem cell can be used as a pharmaceutical composition for preventing or treating diseases caused by ciliopathy or ciliary impairment. The mesenchymal stem cell or the culture medium of mesenchymal stem cell can be used as a cosmetic composition. A method for preventing or treating ciliopathy or ciliary impairment is disclosed.

Abstract: Provided are a membrane-electrode assembly for an electroosmotic pump, the membrane-electrode assembly including a first electrode having a porous structure, containing a first electrochemical reactant, and having applied thereto a (+) or (?) voltage; a first membrane provided on one surface of the first electrode, having a porous structure, and having a (+) or (?) zeta potential; a second electrode provided on one surface of the first membrane opposite to a side of the first electrode, having a porous structure, containing a second electrochemical reactant, and having applied thereto a voltage having a polarity opposite to that of the voltage applied to the first electrode; a second membrane provided on one surface of the second electrode opposite to a side of the first membrane, having a porous structure, and having a zeta potential opposite to that of the zeta potential of the first membrane; and a third electrode provided on one surface of the second membrane opposite to a side of the second electrode, ha

Abstract: The present invention relates to the metabolic engineering of a microbial host for the synthesis of value-added products from oil palm empty fruit brunches (OPEFBs). In one embodiment, the genetically engineered microorganism is Escherichia coli comprising a metabolic pathway consisting of 9 enzymes (11 genes) to utilize depolymerized lignin, namely vanillin, p-coumaric acid, p-hydroxybenzaldehyde, vanillic acid, p-hydroxybenzoic acid and ferulic acid, to produce ?-ketoadipic acid, which can be subsequently converted into commercially important derivatives such as adipic acid and levulinic acid. The enzymes are feruloyl-CoA synthetase (fcs), enoyl-CoA hydratase (ech), vanillin dehydrogenase (vdh), vanillate O-demethylase (vanA; vanA and vanB), p-hydroxy benzoate hydroxylase (pobA), protocatechuate 3,4-dioxygenase {pcaGH; pcaG and pcaH), 3-carboxy-cis, cis-muconate cycloisomerase (pcaB), 4-carboxymuconolactone decarboxylase (pcaC), and ?-ketoadipate enol-lactone hydrolase (pcaD).

Abstract: The present invention provides for a method to increase the free lipoic acid production in an isolated genetically engineered bacteria or yeast cell. The method involves culturing in a cysteine supplemented culture medium the engineered bacteria or yeast that is transformed with a recombinant expression vector encoding polynucleotide molecules that results in the overexpression of the following genes that are linked to at least one promoter: (1) substrate protein (e.g. Gcv3p); (2) octanoyltransferase or lipoyl synthase; (3) cofactor S-adenosyl methionine synthase; and (4) lipoamidase. The invention also relates to the engineered bacteria or yeast cell thereof.

Abstract: Provided are an electroosmotic pump including a membrane; a first electrode disposed on a surface of the membrane and including a first porous support including a first conductor and a first precious metal and a first conductive polymer positioned in or on at least some of pores and surfaces of the first porous support; and a second electrode disposed on another surface of the membrane and including a second porous support including a second conductor and a second precious metal and a second conductive polymer positioned in or on at least some of pores and surfaces of the second porous support, a method of manufacturing the electroosmotic pump, and a fluid pumping system including the electroosmotic pump.

Abstract: A touch display device for preventing the occurrence of a short circuit between routing lines is disclosed. The touch display device includes a dam forming a boundary with an encapsulation unit covering a light-emitting element, and the dam is formed such that the height thereof in a region that overlaps routing lines, which are connected to touch electrodes disposed on the encapsulation unit, and the height thereof in a region that does not overlap the routing lines are different from each other, thereby preventing the occurrence of a short circuit between the routing lines.

Abstract: An electro-osmosis pump system includes an inlet line through which a fluid is introduced, an outlet line through which the fluid is discharged, a first pump disposed between the inlet line and the outlet line and including a first housing in which a first operation fluid is disposed, a second pump disposed in parallel to the first pump between the inlet line and the outlet line and including a second housing in which a second operation fluid disposed, and a power supply configured to supply voltages to the first pump and the second pump. The first pump includes a first membrane, a 1A-th electrode, and a 2A-th electrode, the second pump includes a second membrane, a 1B-th electrode, and a 2B-th electrode, and the power supply supplies the voltage to the 1A-th electrode and the 2A-th electrode, and supplies the voltage to the 1B-th electrode and the 2B-th electrode.

Abstract: The present invention relates to a pharmaceutical composition, for preventing or treating Charcot-Marie-Tooth disorder, comprising mesenchymal stem cells or insulin secreted by mesenchymal stem cells.

Abstract: A display device includes a first base member having a first light-emitting area, a second light-emitting area, and a non-light-emitting area between the first and second light-emitting areas; a second base member on the first base member; a first color filter on a first surface of the second base member that faces the first base member and overlapping with the first light-emitting area; a second color filter on the first surface of the second base member and overlapping with the second light-emitting area; a color pattern on the first surface of the second base member, between the first and second color filters, and overlapping with the non-light-emitting area; a light-shielding member on the color pattern and overlapping with the non-light-emitting area; and a first wavelength conversion pattern on the second color filter and including a first wavelength shifter.

Abstract: The present disclosure provides a display device having a touch sensor for reducing the size of a bezel area. The display device having a touch sensor is configured such that touch electrodes and touch lines are disposed in a mesh shape on an encapsulation layer encapsulating light-emitting elements and such that some of the touch lines are connected to a touch-driving circuit via an upper bezel area, thereby reducing the size of left and right bezel areas.