Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.

Abstract: A nanoparticle delivery system designed for sustained delivery of microRNA-150 (miR-150) to FLT3-overexpressing acute myeloid leukemia (AML) cells, the delivery system comprising poly(amidoamine) (PAMAM) dendrimers complexed with miR-150, wherein at least one dendrimer is surface-functionalized with a ligand specific for FLT3 receptor, and methods for treating AML characterized by FLT3-overexpression are provided.

Abstract: A method for cleaning semiconductor wafer includes putting at least one wafer on a cassette bracket in a first cleaning tank filled with chemical solution; after said wafers have been processed in the first cleaning tank, transferring the wafers from the first cleaning tank to a second cleaning tank with the wafers immersing in the chemical solution; and after said wafers have been processed in the second cleaning tank, taking the wafers out of the second cleaning tank.

Abstract: Embodiments of the present invention provide computer-implemented methods, computer program products and computer systems. Embodiments of the present invention can, in response to receiving performance data associated with records, identify whether the received performance data is associated with long transactions. Embodiments of the present invention can then, in response to determining that the received performance data is associated with long transactions, storing the performance data. Embodiments of the present invention can then classify the stored performance data according to types of transactions the performance data and aggregate the stored performance data based on the classification.

Abstract: A recombinant AAV vector including a sequence for introducing the expression of G protein-coupled receptor 173 (GPR173) and specifically targeting GPR173 expressing neurons in a brain is provided. A method of restoring the excitatory/inhibitory (E/I) balance in brain or for prophylaxis and/or therapy of a neurological condition in a subject in need thereof by administrating the recombinant AAV vector or a GPR173 agonist to the subject is also provided.

Abstract: This disclosure provides methods and apparatuses for repeated transmissions. One method includes: determining, by a terminal device, a plurality of receive beams to be used by a terminal device for receiving at least two transmissions of a transport block; and receiving, by the terminal device, the at least two transmissions of the transport block by using the plurality of receive beams determined by the terminal device.

Abstract: Compounds are provided as inhibitors of CXCR2, having the structure:

Abstract: A location-aware electronic device is provided. The electronic device trains feature extraction layers, reconstruction layers, and classification layers. The training may be based on a reconstruction loss and/or a clustering loss. The electronic device processes a fingerprint to obtain an augmented fingerprint using randomization based on statistics of the fingerprint. The feature extraction layers provide feature data to both the reconstruction layers and the classification layers. The classification layers operate on the codes to obtain an estimated location label. An application processor operates on the estimated location label to provide a location-aware application result to a person.

Abstract: To suppress unnecessary operation of PCS control, provided is a vehicle control device comprising a detection unit for detecting an object located in diagonally forward of an own vehicle as a diagonally forward object; and an ECU including at least one processor. The ECU programmed to execute a collision avoidance control for avoiding a collision between own vehicle and one moving object detected as the diagonally forward object by the detection unit or reducing damage to the collision when the one moving object detected as the diagonally forward object satisfies a predetermined collision condition. The ECU programmed to suppress the collision avoidance control based on the one moving object when the other moving object or a stationary object is detected within a predetermined area in the vicinity of the one moving object by the detecting unit.

Abstract: A container conveying system including a controller, a first robot, and/or a second robot. A first container pickup mechanism is provided on the first robot. A second container pickup mechanism is provided on the second robot. The controller is configured to, in response to a container conveying request, send a first conveying instruction to the first robot if it is determined a target container to be conveyed based on the container conveying request has a size within a first size range; or send a second conveying instruction to the second robot if it is determined the target has a size within a second size range. In warehousing operation scenarios, by jointly using the two robots for operation, containers with various container sizes can be picked up and placed, thus improving utilization rate of a container storage space.

Abstract: An optical system includes a housing defining a cylindrical lens array. A first light source is located in the housing and positioned to emit a first wavelength of light into a first field of illumination impinging on the cylindrical lens array. A second light source is located in the housing and positioned to emit a second wavelength of light into a second field of illumination impinging on the cylindrical lens array. The cylindrical lens array alters the first field of illumination and the second field of illumination and increases an overlap between the first field of illumination and the second field of illumination. A detector is located in the housing and positioned to receive a first redirected portion of the first wavelength of light and a second redirected portion of the second wavelength of light.

Abstract: A method for manufacturing and packaging a special-shaped cigarette includes the following steps: designing inner packaging case paper capable of being folded into a special-shaped cigarette accommodating cavity; folding the inner packaging case paper to form the special-shaped cigarette accommodating cavity; filling an interior of the special-shaped cigarette accommodating cavity with an ordinary cigarette; and shelving for a certain period of time, so that a cross section of the ordinary cigarette changes from a circle to a special shape, and the ordinary cigarette is accommodated in the special-shaped cigarette accommodating cavity. A diameter of an inscribed circle of the special-shaped cigarette accommodating cavity is less than a diameter of the ordinary cigarette, and a material of the inner packaging case paper is a paperboard or a food grade PVC sheet.

Abstract: Presented herein are systems and methods for an end-to-end solution for object removal from a video using adaptive learning. In one or more embodiments, using a pre-trained image inpainting model, in-scene training data may be generated using optical-flow guided sampling. In one or more embodiments, the sampled patches are used to generate a training dataset, which is used to further train the image inpainting model until reaching a stop condition. The adaptively trained inpainting model may be used to generate a modified video in which the desired object or objects have been removed and the corresponding removed portion(s) have been filled (or inpainted) to preserve the integrity of the image.

Abstract: A molecular marker for identifying DNA methylation and thereby detecting the benignity or malignancy of a lung nodule is disclosed. The molecular marker for identifying DNA methylation includes the sequence of, or the completely complementary sequence to, SEQ ID NO:6 or a continuous fragment of at least 55% of the full length of the sequence of, or the completely complementary sequence to, SEQ ID NO:6. Also disclosed are applications of the molecular marker for identifying DNA methylation, including a corresponding detection reagent kit and a corresponding detection method. The disclosed molecular marker combinations for identifying DNA methylation are highly correlated to lung cancer, are highly sensitive and specific when used to detect the benignity or malignancy of a lung nodule, and can increase the detection rate of malignant lung nodules while lowering the false positive rate.

Abstract: Embodiments of this application disclose a beam time synchronization method, for a terminal device to report, to an access network device, that time synchronization information meets a preset condition. The method in embodiments of this application includes: The terminal device determines the time synchronization information based on a time synchronization value of a first beam and a time synchronization value of a second beam. The second beam is a candidate beam or a previous serving beam, and the first beam is a current serving beam. The terminal device sends indication information to the access network device if the time synchronization information meets the preset condition, where the indication information indicates that the time synchronization information meets the preset condition.

Abstract: This application provides a communication method and apparatus. The communication method includes: receiving measurement configuration information from a network device, where the measurement configuration information is used to configure a channel measurement resource and M interference measurement resources, and M is a positive integer greater than or equal to 1; and sending a bitmap to the network device, where the bitmap includes one or more bits, each bit corresponds to one or more interference measurement resources and has a value indicating interference of the one or more interference measurement resources to the channel measurement resource, and the M interference measurement resources include the one or more interference measurement resources.

Abstract: A method for manufacturing and packaging a special-shaped cigarette includes the following steps: designing inner packaging case paper capable of being folded into a special-shaped cigarette accommodating cavity; folding the inner packaging case paper to form the special-shaped cigarette accommodating cavity; filling an interior of the special-shaped cigarette accommodating cavity with an ordinary cigarette; and shelving for a certain period of time, so that a cross section of the ordinary cigarette changes from a circle to a special shape, and the ordinary cigarette is accommodated in the special-shaped cigarette accommodating cavity. A diameter of an inscribed circle of the special-shaped cigarette accommodating cavity is less than a diameter of the ordinary cigarette, and a material of the inner packaging case paper is a paperboard or a food grade PVC sheet.

Abstract: Embodiments of this application provide a method and an apparatus for determining radio channel multipath information and a related device. A server obtains reference signal received powers of a plurality of downlink beams, and determines a path angle and path strength of a propagation path from an antenna in a power angular spectrum cell indicated by each power angular spectrum cell identity to a grid indicated by each grid identity, based on an association relationship between the reference signal received powers of the plurality of downlink beams and the following: a grid identity, a serving cell identity, and a power angular spectrum cell. The server can determine the radio channel multipath information based on the reference signal received powers of the plurality of downlink beams, instead of depending on map and engineering parameter information. This helps improve accuracy of the radio channel multipath information.

Abstract: The present invention provides a high temperature chemical solution supply system for cleaning substrates. The system includes a solution tank, a buffer tank, a first pump and a second pump. The solution tank contains high temperature chemical solution. The buffer tank has a tank body, a vent line and a needle valve. The tank body contains the high temperature chemical solution. An end of the vent line connects to the tank body, and the other end of the vent line connects to the solution tank. The needle valve is mounted on the vent line, wherein the needle valve is adjusted to reach a flow rate to vent gas bubbles inside of the high temperature chemical solution out of the buffer tank through the vent line. An inlet of the first pump connects to the solution tank, and an outlet of the first pump connects to the buffer tank. An inlet of the second pump connects to the buffer tank, and an outlet of the second pump connects to a cleaning chamber in which a substrate is cleaned.

Abstract: The present disclosure discloses a treatment process and treatment system of enhanced up-flow multiphase wastewater oxidation. The treatment process includes the following steps: 1) the wastewater is fed into the up-flow multiphase wastewater oxidation system for oxidation treatment; 2) the wastewater is fed to the solid-liquid separation system for solid-liquid separation, the separated heterogeneous catalytic carrier (5) is fed back to the up-flow multiphase wastewater oxidation system, and the wastewater is fed to the neutralization and degassing system; 3) the wastewater is fed to the neutralization and degassing system to adjust a pH of the wastewater to 5.5-7.5, and then is degassed by stirring; 4) the wastewater is fed to the flocculation and sedimentation system for sludge-water separation, a supernatant is discharged, and an outward harmless treatment is performed after a pressure filtration of a sedimentary iron sludge.