Abstract: The invention relates to a multifunctional nanomaterial comprising a nanorod comprising 1) a noble metal, wherein the nanorod exhibits surface plasmon resonance absorption in the near-infrared spectrum; 2) an up-conversion phosphor that absorbs infrared light and emits visible luminescence; and optionally 3) a biomolecule targeting moiety. The invention further relates to methods of detecting and treating cancer using the multifunctional nanomaterials of the invention.

Abstract: Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. The definition of the substituent groups in the formula I are provided in the specification. The compounds having general formula I have desirable antitumor activity, particularly, and have excellent activity against leukemia strain HL-60, lung cancer A549, H157, H460, H520, bladder cancer T24, J82, prostate cancer LNCap, PC-3, rectal cancer HCT8, HCT116, RkO and the like.

Abstract: The subject invention is directed towards tire components which are comprised of rubber compositions which are comprised of (1) about 2 phr to about 45 phr of a trans-1,4-isoprene-butadiene copolymer which has about 4 weight percent to about 16 weight percent butadiene repeat units and from about 84 weight percent to about 96 weight percent isoprene repeat units, wherein the trans-1,4-isoprene-butadiene copolymer has a Mooney ML 1+4 viscosity which is within the range of about 35 to about 80; and (2) about 55 phr to about 98 phr of at least one other elastomer, preferably a diene based elastomer. The most preferred tire components are those which contain cord reinforcements and require adequate green strength to enhance the tire building and shaping process to maintain cord integrity in the final cured tire.

Abstract: Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. The definition of the substituent groups in the formula I are provided in the specification. The compounds having general formula I have desirable antitumor activity, particularly, and have excellent activity against leukemia strain HL-60, lung cancer A549, H157, H460, H520, bladder cancer T24, J82, prostate cancer LNCap, PC-3, rectal cancer HCT8, HCT116, RkO and the like.

Abstract: This invention relates to a tire having a rubber component, such as a tread. with filler reinforcement containing surface modified graphene and precipitated silica which may be or may include pre-hydrophobated precipitated silica.

Abstract: Preparation of a rubber composition containing a dispersion of aligned exfoliated graphite platelets. Such rubber composition is prepared by a method comprised of a sequential combination of concentrated solvent or dry masterbatching of elastomer and exfoliated graphite platelets, followed by blending the masterbatch (after removing the solvent from the solvent based masterbatch) with additional elastomer(s) and then followed by processing the resulting rubber composition to align the dispersed exfoliated graphite platelets in a substantially parallel relation to each other. Such processing may comprise as least one of extrusion and calendaring the rubber composition. The invention further relates to a tire containing a component comprised of such rubber composition containing a dispersion of aligned exfoliated graphite platelets prepared by the aforesaid method.

Abstract: A pneumatic tire includes a reinforcing ply structure extending between a pair of bead portions, a pair of sidewalls, each sidewall located radially outward of one of the pair of bead portions, a tread radially outward from the reinforcing ply structure, a belt reinforcing structure located radially outward from the reinforcing ply structure and radially inward from the tread, and an innerliner structure extending along an inner surface of the reinforcing ply from a position adjacent one bead portion to a position adjacent the other bead portion. The innerliner structure includes multiple alternating layers of rubber compound and sealant.

Abstract: The present invention is directed to a pneumatic tire comprising a carcass and an innerliner in direct contact with the carcass, the innerliner comprising: a microlayer polymer composite film comprising alternating layers of a polyurethane and an ethylene vinyl alcohol copolymer.

Abstract: A pneumatic tire includes a reinforcing ply structure extending between a pair of bead portions, a pair of sidewalls, each sidewall located radially outward of one of the pair of bead portions, a tread radially outward from the reinforcing ply structure, a belt reinforcing structure located radially outward from the reinforcing ply structure and radially inward from the tread, and an innerliner structure extending along an inner surface of the reinforcing ply from a position adjacent one bead portion to a position adjacent the other bead portion. The innerliner structure includes multiple alternating layers of rubber compound and sealant.

Abstract: This invention relates to a tire having a rubber tread containing functionalized carbon nanotubes and particulate reinforcement comprised of precipitated silica.

Abstract: This invention relates to a rubber composition comprised of diene-based elastomer, precipitated silica and nano-scale exfoliated graphene platelets. A tire is provided having a component comprised of such rubber composition.

Abstract: Preparation of a rubber composition containing a dispersion of aligned exfoliated graphite platelets. Such rubber composition is prepared by a method comprised of a sequential combination of concentrated solvent or dry masterbatching of elastomer and exfoliated graphite platelets, followed by blending the masterbatch (after removing the solvent from the solvent based masterbatch) with additional elastomer(s) and then followed by processing the resulting rubber composition to align the dispersed exfoliated graphite platelets in a substantially parallel relation to each other. Such processing may comprise as least one of extrusion and calendaring the rubber composition. The invention further relates to a tire containing a component comprised of such rubber composition containing a dispersion of aligned exfoliated graphite platelets prepared by the aforesaid method.

Abstract: The subject invention is directed towards tire components which are comprised of rubber compositions which are comprised of (1) about 2 phr to about 45 phr of a trans-1,4-isoprene-butadiene copolymer which has about 4 weight percent to about 16 weight percent butadiene repeat units and from about 84 weight percent to about 96 weight percent isoprene repeat units, wherein the trans-1,4-isoprene-butadiene copolymer has a Mooney ML 1+4 viscosity which is within the range of about 35 to about 80; and (2) about 55 phr to about 98 phr of at least one other elastomer, preferably a diene based elastomer. The most preferred tire components are those which contain cord reinforcements and require adequate green strength to enhance the tire building and shaping process to maintain cord integrity in the final cured tire.

Abstract: This invention relates to a tire having a rubber tread containing functionalized carbon nanotubes and particulate reinforcement comprised of precipitated silica.

Abstract: This invention relates to a tire having a circumferential electrically non-conductive (relatively electrically non-conductive) rubber tread which contains an electrically conductive (relatively electrically conductive) rubber strip extending from an electrically conductive underlying tread base rubber layer (underlying the tread) through the rubber tread to its running surface. The rubber strip contains a dispersion of carbon nanotubes to provide its electrical conductivity and to thereby provide a path of least electrical resistance through the tread to its running surface.

Abstract: This invention relates to a rubber composition comprised of diene-based elastomer, precipitated silica and nano-scale exfoliated graphene platelets. A tire is provided having a component comprised of such rubber composition.