Abstract: The present invention pertains to compounds and polymers which incorporate a boronic acid sensor group (SG) of the formula (I): wherein: J is independently —CH2— or —CH2CH2—; n is independently 0, 1, 2, or 3; and each RR, if present, is independently a ring substituent; and wherein the ring attachment (i.e., where sensor group is attached) is via the 3-, 4-, 5-, or 6-ring position. Such compounds and polymers are useful in the selective chemical detection and/or quantitation of alpha-hydroxy carboxylic acids, such as lactic acid/lactate and malic acid/malate. The present invention also pertains to methods of preparing such compounds and polymers; methods and assays which employ these compounds and polymers; devices (e.g., holographic sensors) and kits for use in such methods and assays, etc.

Abstract: A sensor for the detection of an analyte comprising a cis-diol moiety, which comprises a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a variation of a physical property occurring throughout the volume of the medium, and wherein the medium is a polymer comprising a group of formula (i) wherein n is 0, 1, 2, 3 or 4; each X (if present) is independently is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom; and Y is a spacer which, when n is 0 or otherwise optionally, is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom. Such a sensor may be used for the detection of glucose.

Abstract: A sensor for the detection of an analyte comprising a cis-diol moiety, which comprises a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a variation of a physical property occurring throughout the volume of the medium, and wherein the medium is a polymer comprising a group of formula (I): wherein n is 0, 1, 2, 3 or 4; each X (if present) is independently is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom; and Y is a spacer which, when n is 0 or otherwise optionally, is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom. Such a sensor may be used for the detection of glucose.

Abstract: The present invention is directed to a method of conducting static electricity in a pneumatic tire, comprising the steps of mixing a rubber compound comprising at least one diene based rubber, from 60 to 150 phr of precipitated silica, less than 40 phr of carbon black, and from 1 to 10 phr of carbon nanotubes having a length of at least 5 microns; forming a tire tread from the rubber compound; and including the tire tread in the tire; wherein the volume resistivity of the tire tread is less than 1×109 ohm-cm as measured by ASTM D257-98.

Abstract: A high-power and high-gain ultra-short gate HEMT device has exceptional gain and an exceptionally high breakdown voltage provided by an increased width asymmetric recess for the gate electrode, by a composite channel layer including a thin indium arsenide layer embedded in the indium gallium arsenide channel layer and by double doping through the use of an additional silicon doping spike. The improved transistor has an exceptional 14 dB gain at 110 GHz and exhibits an exceptionally high 3.5-4 V breakdown voltage, thus to provide high gain, high-power and ultra-high frequency in an ultra-short gate device.

Abstract: A process of preparing a nanocomposite comprised of an elastomer and at least partially exfoliated, intercalated water-swellable clay.

Abstract: Pneumatic rubber tire having at least one component of a polybutadiene-rich rubber composition comprised of a blend of a continuous phase of a specialized cis 1,4-polybutadiene rubber and a dispersed phase comprised of a composite of styrene/butadiene elastomer which contains a dispersion of at least partially exfoliated, intercalated, clay platelets, wherein said cis 1,4-polybutadiene rubber and styrene/butadiene elastomer have spatially defined glass transition temperatures, wherein said blend contains amorphous silica and carbon black reinforcement. Such tire component may be, for example, a circumferential tread having a running surface intended to be ground-contacting or a sidewall insert.

Abstract: The present invention is directed to a pneumatic tire comprising at least one component, the at least one component comprising a rubber composition, the rubber composition comprising from about 50 to about 100 parts by weight, per 100 parts by weight of elastomer, of a vinylpyridine-styrene-butadiene (VPSBR) elastomer comprising units derived from monomers comprising styrene, 1,3-butadiene, and vinylpyridine monomers which have the structural formula: wherein R1 represents a hydrogen atom or a straight chain or branched alkyl group containing 1 to 4 carbon atoms, wherein the VPSBR comprises from about 0.1 to about 8 percent by weight of vinylpyridine monomer; from 0 to about 50 phr of at least one additional diene-based elastomer; from about 5 to about 15 phr of an at least partially exfoliated clay; and from about 1 to about 40 phr of a polyoctenamer.

Abstract: This invention relates to an aqueous based process for the preparation of intercalated and/or exfoliated natural or synthetic clays using block copolymers in latex form containing at least one non-polar block and one or more cationic blocks, wherein the block copolymers are prepared by an emulsion controlled free radical polymerization method.

Abstract: The present invention relates to unglycosylated isolated and purified recombinant polypeptides comprising a fusion protein able to bind to autoantibodies produced in response to an autoimmune disease associated with an immune reaction to a TSH-receptor (TSHR). Also disclosed are methods of detecting and/or quantifying such autoantibodies using the isolated and purified recombinant polypeptides and respective kits.

Abstract: The present invention pertains to compounds and polymers which incorporate a boronic acid sensor group (SG) of the formula (I): wherein: J is independently —CH2— or —CH2CH2—; n is independently 0, 1, 2, or 3; and each RR, if present, is independently a ring substituent; and wherein the ring attachment (i.e., where sensor group is attached) is via the 3-, 4-, 5-, or 6-ring position. Such compounds and polymers are useful in the selective chemical detection and/or quantitation of alpha-hydroxy carboxylic acids, such as lactic acid/lactate and malic acid/malate. The present invention also pertains to methods of preparing such compounds and polymers; methods and assays which employ these compounds and polymers; devices (e.g., holographic sensors) and kits for use in such methods and assays, etc.

Abstract: A pneumatic tire comprising at least one component, the at least one component comprising a rubber composition comprising: an vinylpyridine-styrene-butadiene (VPSBR) elastomer derived from monomers comprising vinylpyridine, styrene, and butadiene, wherein the VPSBR comprises from about 0.1 to about 8 percent by weight of vinylpyridine; and from about 5 to about 15 parts by weight, per 100 parts by weight of VPSBR, of an at least partially exfoliated clay.

Abstract: A process of preparing a nanocomposite comprised of an elastomer and at least partially exfoliated, intercalated water-swellable clay, comprising the steps of (A) forming a first blend of water-swelled clay and anionic polymer particle emulsion by blending: (1) an aqueous mixture comprised of water and a multilayered water-swellable clay, exclusive of an intercalant for said clay, wherein said water-swellable clay is comprised of a plurality of stacked platelets with water-expanded galleries between said platelets, wherein said galleries contain naturally occurring cationic ion exchangeable ions therein, and (2) an emulsion of anionic synthetic vinylpyridine-styrene-butadiene terpolymer (VPSBR) elastomer particles as an aqueous pre-formed elastomer emulsion having a pH in a range of from about 6 to about 11, comprised of anionic elastomer particles (elastomer particles having anions on the surface derived from an anionic surfactant) prepared by aqueous free radical induced polymerization of monomers in th

Abstract: This invention relates to preparation of nanocomposites comprised of elastomer and a dispersion of an at least partially exfoliated water swellable clay and to rubber compositions containing such nanocomposite and articles of manufacture which contain at least one component thereof. The nanocomposite is prepared by addition of a water suspension of water swellable clay particles to an anionic aqueous emulsion of elastomer particles to form a mixture to which an amine having at least two amine centers is added to intercalate and at least partially exfoliate the water swelled clay particles by an ion exchange within the galleries of the multilayered clay with cation exchangeable ion(s) and to aid in coagulating the elastomer and resultant clay particles to form said nanocomposite.

Abstract: Compositions comprising chromium (III) 1:3 complexes comprising amino acids and methods of use thereof are provided.

Abstract: In some embodiments a connector is to couple a peripheral, and a detector coupled to the connector is to detect if the peripheral is disconnected from the connector in response to a first reserved pin and a second reserved pin.

Abstract: Described herein is a method of cloning synthetic oligos (including in situ synthesized oligos) into an (one or more) expression vector for library (e.g., shRNA library) production. The oligos are synthesized with one portion of the first stem of the hairpin, followed by a first loop sequence, the complete second stem, a second loop sequence, and finished with the remaining portion of the first stem of the hairpin. The two portions of the first stem anneal to the second stem, juxtaposing the 5? end close to the 3? end of the oligo. The methods described herein selected for hairpins with perfectly base-paired stems. After annealing, a ligase is added to the annealed oligos and the base-paired hairpins are preferentially annealed, and ligated, creating closed circular oligos. The now circularized hairpins served as templates for rolling circle amplification using a polymerase with high processivity.

Abstract: Compositions comprising chromium (III) 1:3 complexes comprising amino acids and methods of use thereof are provided.

Abstract: In some embodiments a connector is to couple a peripheral, and a detector coupled to the connector is to detect if the peripheral is disconnected from the connector in response to a first reserved pin and a second reserved pin. Other embodiments are described and claimed.