Abstract: Methods and compositions are disclosed to target tumor cells with embodiments of the LIGHT proteins linked fused or conjugated to a targeting agent. These compositions bind to both human and mouse receptors with affinity sufficient to conduct preclinical and clinical trials, and with increased affinity as compared to the wild type human LIGHT protein. The targeting of embodiments of LIGHT to tumor cells reduces tumor growth and reduces metastases.

Abstract: A method, an apparatus and a device for charging a battery are provided in the present disclosure. The method may include: defining a charging current In for an Nth charging stage of a charging process based on charging capability of the battery, wherein In<In-1; defining a charge cutoff voltage Vn for the Nth charging stage of the charging process, wherein Vn>Vn-1 and Vn is smaller than a theoretical charge cutoff voltage Vmax; in case that the N?1th charging stage is not a last charging stage, charging the battery with In-1 during the N?1th charging stage and proceeding to the Nth charging stage when a voltage across the battery reaches Vn-1; and in case that the N?1th charging stage is the last charging stage, charging the battery with In-1 during the N?1th charging stage and stopping charging when the voltage across the battery reaches Vn-1.

Abstract: In order to invite individuals to join a social network, telephone contact information of a user of the social network is extracted, with the user's permission, from a phonebook associated with a telephone application on the user's portable electronic device. Then, the extracted telephone contact information is shared across different platforms to the user's desktop computer, and telephone numbers in the extracted telephone contact information are identified. These telephone numbers are associated with other portable electronic devices, and with individuals that are not currently members of the social network. After receiving confirmation of a telephone number from the user (e.g., via the desktop computer), the location of the associated portable electronic device is determined. Based on the telephone number and the location, an invitation to join the social network is conditionally provided to the portable electronic device, via a Short Message Service (SMS) message.

Abstract: Techniques for tracking profile completeness among members of an online social networking system are described. According to various embodiments, profile completion score criteria information identifies a profile completion score weight value associated with each of a plurality of member profile fields available in member profiles of an online social networking service. A specific member profile associated with a specific member of the online social networking service is accessed, and one or more of the plurality of member profile fields that have been completed in the specific member profile are identified. Thereafter, the profile completion score weight values associated with the member profile fields that have been completed in the specific member profile are determined, based on the profile completion score criteria information. Based on the determined profile completion score weight values, a profile completion score is then generated for the specific member profile.

Abstract: A range of alloys of Mg and at least one of Cu, Si, Ni and Na alloys that is particularly suitable for hydrogen storage applications. The alloys of the invention are formed into binary and ternary systems. The alloys are essentially hypoeutectic with respect to their Cu and Ni contents, where one or both of these elements are present, but range from hypoeutectic through to hypereutectic with respect to their Si content when that element is also present. The terms hypoeutectic and hypereutectic do not apply to Na if it is added to the alloy. The alloy compositions disclosed provide high performance alloys with regard to their hydrogen storage and kinetic characteristics. They are also able to be formed using conventional casting techniques which are far cheaper and more amenable to commercial use than the alternative ball-milling and rapid solidification techniques which are much more expensive and complex.

Abstract: A method, an apparatus and a system for controlling charging of a battery module are provided in the present disclosure. The method for controlling charging of the battery module may include: acquiring an internal pressure value of the battery module; determining a target pressure threshold range to which the acquired internal pressure value of the battery module belongs, based on a plurality of predefined pressure threshold ranges; obtaining a target charge cutoff voltage corresponding to the target pressure threshold range, based on a correspondence relationship between a plurality of predefined charge cutoff voltage and the plurality of predefined pressure threshold ranges; and controlling the battery module to be charged based on the obtained target charge cutoff voltage.

Abstract: An optical fiber connector includes a main body (1), a sleeve (2), and a plug (3). The main body (1) includes a first cube and a second cube that are formed by means of injection molding, where a first cavity (1o) is disposed inside the first cube, and the first cavity (1o) is used to adapt to an optical fiber sub-assembly inserted from a first end face of the first cube; at least two hook-like structures (1n) are formed, by means of injection molding, on the first cube extending from a second end face that is parallel to the first end face into the first cavity (1o), and the hook-like structures (1n) are used to tightly lock the optical fiber sub-assembly when the optical fiber sub-assembly is inserted from the first end face.

Abstract: The disclosed embodiments provide a system for processing data. During operation, the system obtains a count of actions associated with a member of a social network, wherein the count comprises a set of action types and a number of actions associated with the member for each of the action types. Next, the system uses the count to calculate a set of scores for measuring the value of the social network to the member, wherein the set of scores is associated with researching and contacting people, building a network, keeping up with connections, staying informed and building knowledge, establishing and managing a reputation, and getting hired. The system then outputs the scores for use in characterizing and improving the value of the social network for the member.

Abstract: Techniques for optimizing a guided edit process for editing a member profile page are described. According to various embodiments, incomplete member profile fields in a member profile associated with member of an online social networking service are identified. Profile completion score weight values associated with the incomplete member profile fields in the member profile are then determined. Thereafter, the incomplete member profile fields in the member profile are ranked, based on the profile completion score weight values associated with each of the incomplete member profile fields. A list of one or more of the highest ranked incomplete member profile fields are then displayed, together with a prompt recommending the member to complete the identified incomplete member profile fields.

Abstract: The disclosure relates to a method of producing induced beta cells from urine-derived cells, the method comprising providing urine-derived cells; inducing the urine-derived cells by culturing said urine-derived cells in a primary induction culture medium comprising an effective amount of at least one small molecule reprogramming factor(s) for a first period of time to obtain induced endoderm cells; inducing the induced endoderm cells by culturing said induced endoderm cells in a secondary induction culture medium comprising an effective amount of at least one small molecule reprogramming factor(s) for a second period of time to obtain induced pancreatic precursor cells; and inducing the induced pancreatic precursor cells by culturing said pancreatic precursor cells in a tertiary induction culture medium comprising an effective amount of at least one small molecule reprogramming factor(s) for a third period of time to obtain induced beta cells.

Abstract: A system determines an intent of a current user who is interacting with an online social networking system, and requests information from the current user based on the determined intent of the current user. The system then receives the requested information from the current user, and provides a service or information to the current user based on the intent of the current user and the information provided by the current user.

Abstract: Methods and compositions are disclosed to target tumor cells with embodiments of the LIGHT proteins linked fused or conjugated to a targeting agent. These compositions bind to both human and mouse receptors with affinity sufficient to conduct preclinical and clinical trials, and with increased affinity as compared to the wild type human LIGHT protein. The targeting of embodiments of LIGHT to tumor cells reduces tumor growth and reduces metastases.

Abstract: System and techniques for activity sensing online preference assay are described herein. A count for an action completed by a member of a social network service may be detected over a first period of time. The member may be labeled with an online activity preference based on the count and a subset of the first period of time. A plurality of member activities corresponding with the online activity preference may be collected for a second period of time prior to obtaining the initial indication. Respective decision trees of a set of decision trees may be traversed based on a set of inputs comprising the collected plurality of member activities to determine a probability that the online activity preference corresponds with the member. An actual online activity preference may be derived for the member using an aggregation of the determined probability for the respective decision trees of the set of decision trees.

Abstract: System and techniques for activity sensing online preference assay are described herein. An initial indication of an online activity preference for a member of a social network service may be obtained. A plurality of member activities corresponding with the online activity preference for a period of time subsequent to obtaining the initial indication may be collected. Respective decision trees of a set of decision trees may be traversed based on a set of inputs comprising the collected plurality of member activities to determine a probability that the online activity preference corresponds with the member. An actual online activity preference may be derived for the member using an aggregation of the determined probability for the respective decision trees of the set of decision trees.

Abstract: Antibody-LIGHT fusion products or conjugates stimulate immunity against tumors and eradicate metastases. Tumor-specific antibodies coupled with LIGHT effectively target metastatic tumors and reduces cancer metastases.

Abstract: Disclosed is a device and method for dynamic extrusion molding of plastic articles having variable micro-channel. The device mainly includes a single-screw extruder, a dynamic extrusion die, a fluid source, a water sink, a tractor, a winding device, and a data acquisition and control system. Near outlet of extrusion die, when the end portion of a syringe needle is at different positions, the inner diameter of the micro-channel of the extrusion molded plastic article is also different. When the hollow syringe core within the dynamic extrusion die performs a high-frequency short-range vibration along an extrusion direction, the inner diameter of the micro-channel of the extruded plastic articles is dynamically variable. The plastic articles of variable micro-channel of the present invention has novel structure with high dimensional accuracy, and a variety of varying patterns, it can be stably produced by simple processing equipment with high level of automation.

Abstract: Techniques for tracking profile completeness among members of an online social networking system are described. According to various embodiments, profile completion score criteria information identifies a profile completion score weight value associated with each of a plurality of member profile fields available in member profiles of an online social networking service. A specific member profile associated with a specific member of the online social networking service is accessed, and one or more of the plurality of member profile fields that have been completed in the specific member profile are identified. Thereafter, the profile completion score weight values associated with the member profile fields that have been completed in the specific member profile are determined, based on the profile completion score criteria information. Based on the determined profile completion score weight values, a profile completion score is then generated for the specific member profile.

Abstract: A system and method for generating a profile value score to prioritize members for opportunities. The system receives a member opportunity request. In response, the system generates a list of members in response to the received member opportunity request, wherein the list of members is determined based on member profile data stored at a social networking system. For each member in the generated list of members, the system generates a profile value score based on the stored member profile data. The system ranks the members of the generated list at least in part based on the generated profile value scores. The system then selects one or more members in the list of members based on the ranking of members in the generated list.

Abstract: The disclosed embodiments relate to a system for analyzing performance in an online professional network. During operation, the system receives time series data for user actions, wherein for each user action, the time series data comprises a series of numbers associated with consecutive time intervals, wherein a given number indicates a number of times the user action occurred during the time interval. The system also receives time series data for performance metrics, wherein for each performance metric, the time series data comprises a series of numbers associated with consecutive time intervals, wherein a given number indicates the number of times the performance metric occurred during the time interval. The system then performs a time series analysis on the received time series data for user actions and performance metrics to determine relationships between the user actions and the performance metrics.

Abstract: Compositions, kits and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the cancer chemosensitive and/or radiosensitive.