Patents by Inventor Yariv Donde

Yariv Donde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents
    Patent number: 8557860
    Abstract: A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed. Also disclosed herein are compounds comprising or derivatives thereof, or pharmaceutically acceptable salts, tetrazoles, or prodrugs of compounds of the structure or derivatives thereof, said derivatives being described in detail herein. Also disclosed herein are methods of treating diseases or conditions, including glaucoma and elevated intraocular pressure. Compositions and methods of manufacturing medicaments related thereto are also disclosed.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 15, 2013
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Robert M. Burk, Michael Garst
  • Therapeutic cyclopentane derivatives
    Patent number: 8530471
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 4, 2009
    Date of Patent: September 10, 2013
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Substituted cyclopentanes having prostaglandin activity
    Patent number: 8487091
    Abstract: Disclosed herein are compounds represented by the formula: Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: July 16, 2013
    Assignee: Allergan, Inc.
    Inventors: Mark Holoboski, Robert M. Burk, Mari Posner, Yariv Donde, David W. Old
  • Therapeutically active cyclopentanes
    Patent number: 8299068
    Abstract: Disclosed herein are compounds having a formula: Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: October 30, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Therapeutic compounds
    Patent number: 8278347
    Abstract: A compound having a structure is disclosed herein. Compositions, medicaments, and therapeutic methods related thereto are also disclosed.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: October 2, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Therapeutic compounds
    Patent number: 8263593
    Abstract: Compounds comprising formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein J, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed, for treating baldness, glaucoma or inflammatory bowel diseases.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: September 11, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents
    Patent number: 8168680
    Abstract: A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed. Also disclosed herein are compounds comprising or derivatives thereof, or pharmaceutically acceptable salts, tetrazoles, or prodrugs of compounds of the structure or derivatives thereof, said derivatives being described in detail herein. Also disclosed herein are methods of treating diseases or conditions, including glaucoma and elevated intraocular pressure. Compositions and methods of manufacturing medicaments related thereto are also disclosed.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: May 1, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Robert M. Burk, Michael E. Garst
  • Therapeutic compounds
    Patent number: 8044092
    Abstract: A compound having a substituted five or six-membered carbocycle or heterocycle directly bonded to a substituted aryl or heteroaryl ring, wherein said compound has an EC50 value of 20 nM or less at the prostaglandin EP2 receptor according to the cAMP assay. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: October 25, 2011
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Robert M. Burk, David W. Old
  • THERAPEUTICALLY ACTIVE CYCLOPENTANES
    Publication number: 20110190286
    Abstract: Disclosed herein are compounds having a formula: Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Application
    Filed: January 21, 2011
    Publication date: August 4, 2011
    Applicant: ALLERGAN, INC.
    Inventors: Yariv Donde, Jeremiah H. NGUYEN
  • Treatment Of Inflammatory Bowel Disease
    Publication number: 20110172435
    Abstract: Disclosed herein is a method comprising administering a compound to a mammal suffering from an inflammatory bowel disease for the treatment of said disease, said compound having a structure according to Formula I wherein X, Y, B, R2, R3, R4, R5, R6 and n have the meanings found herein.
    Type: Application
    Filed: November 12, 2010
    Publication date: July 14, 2011
    Applicant: ALLERGAN, INC.
    Inventors: Yariv Donde, Jeremiah H. Nguyen, Karen M. Kedzie, Daniel W. Gil, John E. Donello, Wha-Bin Im
  • Combination Therapy For Glaucoma
    Publication number: 20110152328
    Abstract: Disclosed herein is method of treating glaucoma or ocular hypertension comprising administering a prostaglandin agonist and a second therapeutically active agent to a mammal in need thereof, wherein said second therapeutically active agent is selected from: ?-Blockers, Adrenergic Agonists, non-selective adrenergic agonists, ?2-selective adrenergic agonists, Carbonic Anhydrase Inhibitors, Cholinergic Agonists, direct acting cholinergic agonists, chlolinesterase inhibitors, Glutamate Antagonists, Ca2+ channel blockers, Prostamides, Prostaglandins, Cannabinoids, and combinations thereof. Compositions and medicaments containing a combination of these two active agents are also disclosed.
    Type: Application
    Filed: April 13, 2009
    Publication date: June 23, 2011
    Inventors: Scott M. Whitcup, Robert M. Burk, David W. Old, Yariv Donde, Wha-Bin Im, Mark A. Holoboski
  • THERAPEUTIC COMPOUNDS
    Publication number: 20110152255
    Abstract: Compounds comprising formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein J, B, Y, and A are as described in claims 1-13. Methods, compositions, and medicaments related thereto are also disclosed, for treating baldness, glaucoma or inflammatory bowel diseases.
    Type: Application
    Filed: April 21, 2009
    Publication date: June 23, 2011
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Therapeutic compounds
    Patent number: 7964599
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: June 21, 2011
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Therapeutic compounds
    Patent number: 7964634
    Abstract: Compounds having a structure are disclosed herein. Compositions, methods, and medicaments related to the therapeutic use of these compounds are also disclosed.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: June 21, 2011
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen, Mark Holoboski, Mari Posner, Robert M. Burk
  • Thiophenyl prostaglandin derivatives for treating glaucoma and ocular hypertension
    Patent number: 7964595
    Abstract: Disclosed herein is a compound according to one of the formulas wherein R is Additionally, pharmaceutically acceptable salt thereof, and methods of treating disease, medicaments, and compositions related thereto, are further elaborated herein.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: June 21, 2011
    Assignee: Allergan, Inc.
    Inventors: Brent A. Johnson, David W.. Old, Yariv Donde, Robert M. Burk
  • Thiophenyl prostaglandin derivatives for treating glaucoma and ocular hypertension
    Patent number: 7960431
    Abstract: Disclosed herein is a compound according to one of the formulas or a pharmaceutically acceptable salt thereof, medicaments for the treatment of glaucoma or ocular hypertension and compositions related thereto, as further elaborated herein.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: June 14, 2011
    Assignee: Allergan, Inc.
    Inventors: Brent A. Johnson, David W. Old, Yariv Donde, Robert M. Burk
  • CYCLOPENTANE HEPTAN(ENE)OIC ACID, 2-HETEROARYLALKENYL DERIVATIVES AS THERAPEUTIC AGENTS
    Publication number: 20110130439
    Abstract: A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed. Also disclosed herein are compounds comprising or derivatives thereof, or pharmaceutically acceptable salts, tetrazoles, or prodrugs of compounds of the structure or derivatives thereof, said derivatives being described in detail herein. Also disclosed herein are methods of treating diseases or conditions, including glaucoma and elevated intraocular pressure. Compositions and methods of manufacturing medicaments related thereto are also disclosed.
    Type: Application
    Filed: February 8, 2011
    Publication date: June 2, 2011
    Applicant: ALLERGAN, INC.
    Inventors: Yariv Donde, Robert M. Burk, Michael E. Garst
  • THERAPEUTIC CYCLOPENTANE DERIVATIVES
    Publication number: 20110112166
    Abstract: Compounds comprising formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein B, Y, and A are as described in claims 1-10. Methods, compositions, and medicaments related thereto are also disclosed, for treating baldness, glaucoma or inflammatory bowel diseases.
    Type: Application
    Filed: May 4, 2009
    Publication date: May 12, 2011
    Applicant: ALLERGAN, INC
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • CYCLOPENTANE HEPTAN(ENE)OIC ACID, 2-HETEROARYLALKENYL DERIVATIVES AS THERAPEUTIC AGENTS
    Publication number: 20110082184
    Abstract: A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed. Also disclosed herein are compounds comprising or derivatives thereof, or pharmaceutically acceptable salts, tetrazoles, or prodrugs of compounds of the structure or derivatives thereof, said derivatives being described in detail herein. Also disclosed herein are methods of treating diseases or conditions, including glaucoma and elevated intraocular pressure. Compositions and methods of manufacturing medicaments related thereto are also disclosed.
    Type: Application
    Filed: December 14, 2010
    Publication date: April 7, 2011
    Applicant: ALLERGAN, INC.
    Inventors: Yariv Donde, Robert M. Burk, Michael Garst
  • Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents
    Patent number: 7906552
    Abstract: A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed. Also disclosed herein are compounds comprising or derivatives thereof, or pharmaceutically acceptable salts, tetrazoles, or prodrugs of compounds of the structure or derivatives thereof, said derivatives being described in detail herein. Also disclosed herein are methods of treating diseases or conditions, including glaucoma and elevated intraocular pressure. Compositions and methods of manufacturing medicaments related thereto are also disclosed.
    Type: Grant
    Filed: August 10, 2004
    Date of Patent: March 15, 2011
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Robert M. Burk, Michael E. Garst