Patents by Inventor Yasmin A. Chandrasekher

Yasmin A. Chandrasekher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of interleukin-19 to treat cervical cancer
    Publication number: 20030219379
    Abstract: The present invention relates to the anti-cancer activity of IL-19 polypeptide molecules. IL-19 is a cytokine involved in inflammatory processes and human disease. The present invention includes Use of IL-19 for decreasing proliferation of cervical cancer cells, treating cervical cancer, amongst other uses disclosed. IL-19 polypeptides can be administered alone, or can be fused to cytotoxic moieties, and can be administered in conjunction with radiation or chemotherapeutic agents.
    Type: Application
    Filed: April 8, 2003
    Publication date: November 27, 2003
    Inventors: Yasmin A. Chandrasekher, Patricia A. McKernan
  • Use of interleukin-24 to treat ovarian cancer
    Publication number: 20030215388
    Abstract: The present invention relates to the anti-cancer activity of IL-24 polypeptide molecules. IL-24 is a cytokine involved in inflammatory processes and human disease. The present invention includes Use of IL-24 for decreasing proliferation of ovarian cancer cells, treating ovarian cancer, amongst other uses disclosed. IL-24 polypeptides can be administered alone, or can be fused to cytotoxic moieties, and can be administered in conjunction with radiation or chemotherapeutic agents.
    Type: Application
    Filed: April 8, 2003
    Publication date: November 20, 2003
    Inventors: Yasmin A. Chandrasekher, Patricia A. McKernan
  • Method for treating cervical cancer
    Publication number: 20030161811
    Abstract: Use of Interleukin-20 for treating cervical cancer or cells infected with human papilloma virus. IL-20 can be administered alone or in conjunction with radiation or chemotherapeutic agents or surgical excision of the involved cells or lesions.
    Type: Application
    Filed: December 17, 2002
    Publication date: August 28, 2003
    Inventors: Yasmin A. Chandrasekher, Patricia A. McKernan
  • Method for treating inflammation using soluble receptors to interleukin-20
    Patent number: 6610286
    Abstract: A method for treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Examples of such diseases are adult respiratory disease, psoriasis, eczema, contact dermatitis, atopic dermatitis, septic shock, multiple organ failure, inflammatory lung injury, bacterial pneumonia, inflammatory bowel disease, rheumatoid arthritis, asthma, ulcerative colitis and Crohn's disease.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: August 26, 2003
    Assignee: ZymoGenetics, Inc.
    Inventors: Penny Thompson, Donald C. Foster, Wenfeng Xu, James D. Kelly, Hal Blumberg, Yasmin A. Chandrasekher
  • Pancreatic and ovarian polypeptide, zsig58
    Publication number: 20020182677
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig58, a novel member of the TTGR family of proteins. The polynucleotides encoding zsig58 may, for example, be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
    Type: Application
    Filed: February 26, 2002
    Publication date: December 5, 2002
    Applicant: ZymoGenetics, Inc.
    Inventors: Paul O. Sheppard, Yasmin A. Chandrasekher
  • Method for treating inflammation
    Publication number: 20020085992
    Abstract: A method for treating down-regulating IL-19 or mda7 by administering the soluble IL-20RA/IL-20R heterodimeric receptor.
    Type: Application
    Filed: September 13, 2001
    Publication date: July 4, 2002
    Inventors: Yasmin A. Chandrasekher, Stephen R. Jaspers
  • Method for treating inflammation
    Publication number: 20020042366
    Abstract: A method for treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Examples of such diseases are adult respiratory disease, psoriasis, eczema, contact dermatitis, atopic dermatitis, septic shock, multiple organ failure, inflammatory lung injury, bacterial pneumonia, inflammatory bowel disease, rheumatoid arthritis, asthma, ulcerative colitis and Crohn's disease.
    Type: Application
    Filed: December 22, 2000
    Publication date: April 11, 2002
    Inventors: Penny Thompson, Donald C. Foster, Wenfeng Xu, Karen L. Madden, James D. Kelly, Cindy A. Sprecher, Hal Blumberg, Maribeth A. Eagan, Stephen R. Jaspers, Yasmin A. Chandrasekher, Julia E. Novak