Abstract: The present invention provides a method of preparing a recycled cementitious material by a phosphogypsum-assisted carbon sequestration pretreatment process. The method includes: (1) placing 100 mass parts of phosphogypsum, 1 to 2 mass parts of grinding aid, 10 to 20 mass parts of sodium-containing alkali component, 150 to 300 mass parts of zirconia balls, and 150 to 300 mass parts of water into a wet grinding tank for wet grinding. After 10 min to 30 min of wet grinding, introducing CO2 at a flow rate of 1.5 to 2.2 mass parts/min to keep a temperature of a wet grinding slurry below 40° C. When the wet grinding slurry reaches pH=10, ending the wet grinding and sieving out a wet grinding slurry; (2) mixing the wet grinding slurry with 700 to 1000 mass parts of slag and 100 to 350 mass parts of water to obtain a recycled cementitious material.

Abstract: The present disclosure provides methods and compositions for the treatment of cancer using an ACAT1 inhibitor in combination with an immune checkpoint inhibitor. The immune checkpoint inhibitor may inhibit the programmed cell death protein 1 (PD-1), programmed death-ligand 1 (PD-L1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), lymphocyte-activation protein 3 (LAG-3), or combinations thereof. The ACAT1 inhibitor may be avasimibe, pactimibe, or purpactins, without limitation.

Abstract: A Cu-based alloy according to the present invention comprises 1.0-2.0 wt % Cr, 0.5-1.5 wt % Nb, 0.1-0.5 wt % Zr, and balance Cu. The alloy has a matrix and grain boundaries, and has Cr2Nb precipitates within the grain boundaries and at least one selected from the group consisting of CuZr and Cr precipitates in the grain matrix. The CuZr precipitates can be at least one selected from the group consisting of Cu5Zr and Cu51Zr14 precipitates. A method of making a CuCrNbZr alloy is also disclosed.

Abstract: Methods of increasing sIgA levels in an individual's oral cavity are disclosed. The methods comprise applying effective amounts of zinc oxide, zinc citrate, and arginine Methods of increasing the concentration of sIgA in the individual's mucosa pellicle in the oral cavity are disclosed. Methods of increasing phagocytotic activity of phagocytotic cells in the individual's oral cavity are also disclosed. In addition, methods of increasing levels of ?-Defensin 1 in the individual's oral cavity are disclosed.

Abstract: The present invention relates generally to glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a spacer containing ((2-oxoethyl)thio)). In an aspect the invention provides oxo-eT linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a ((2-oxoethyl)thio) spacer having the formula (I): wherein: A is a group (C?X)m wherein X is S or O and m is 0 or 1; B is a bond, O, or CH2; and when m is 0, B can also be (C?O); R is a C2-C16 alkylene, C2-C16 heteroakylene, NH—C(?O)—C2-C16 alkylene, or NH—C(?O)—C2-C16 heteroakylene, wherein said alkylene and heteroalkylene are optionally substituted by 1, 2 or 3 groups independently selected from COOR? where R? is selected from H, methyl, ethyl or propyl. The invention further relates to immunogenic compositions comprising such glycoconjugates, and to methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: The present disclosure provides compositions that enable sustained release of a small molecule tyrosine kinase inhibitor, such as axitinib from a bioerodible polyester polymer implant for the treatment of disease. The composition is especially suitable for treating ophthalmic indications, such as neovascular age related macular degeneration and diabetic macular edema, by intravitreal injection of the implant. The implant is designed to be pre-loaded into a small diameter needle and injected via self-sealing scleral needle penetration at the pars plana. Small molecule tyrosine kinase inhibitors may be released from the implants over a period of one week to three years.

Abstract: The present disclosure provides a method for quantitative evaluation on a sensitivity of a shale oil and gas reservoir to injected fluids. The method includes the following steps: (I) preparation of rock samples; (II) quantitative evaluation on sensitivities of a shale porosity and a bedding fracture permeability to an injected fluid; and (III) quantitative evaluation on a sensitivity of a shale matrix permeability to an injected fluid. A method for comprehensive evaluation on a sensitivity of a shale oil and gas reservoir to injected fluids is innovatively provided based on the nuclear magnetic resonance testing technology with two basic physical property parameters: porosity and permeability. The method realizes quantitative evaluation on sensitivities of pores of different sizes and matrix of shale and a bedding fracture permeability to injected fluids, and realizes quantitative and accurate evaluation on a sensitivity of a shale oil and gas reservoir to injected fluids.

Abstract: Some embodiments relate to a roofing membrane. The roofing membrane comprises a scrim. The scrim has a top surface and a bottom surface. The roofing membrane comprises a cap layer on the top surface of the scrim. The cap layer comprises a first non-styrenic polypropylene polymer, a first polypropylene impact copolymer, and a first olefin block copolymer. The roofing membrane comprises a core layer on the bottom surface of the scrim. The core layer comprises a second non-styrenic polypropylene polymer, a second polypropylene impact copolymer, and a second olefin block copolymer. The roofing membrane is configured to prevent migration of at least one oil from a layer to the roofing membrane. Some embodiments relate to a roofing structure comprising the roofing membrane, a method for installing the roofing membrane, and the like.

Abstract: The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions.

Abstract: The invention provides stable aqueous pharmaceutical formulations comprising an anti-PDL1 antibody. The invention also provides methods for making such formulations and methods of using such formulations.

Abstract: Some embodiments relate to a roofing accessory. The roofing accessory comprises a protruding member extending from a base member. The base member surrounds at least a portion of an outer edge of a bottom end of the protruding member. The base member has a top surface, a bottom surface opposite the top surface, and an outer edge. The bottom surface of the base member has a weldable portion and an adherable portion between the weldable portion and the outer edge of the bottom end of the protruding member. The roofing accessory comprises an adhesive disposed on the adherable portion of the bottom surface of the base member. The adhesive is not disposed on the weldable portion of the bottom surface of the base member.

Abstract: The present application discloses an optical receiving device, including: a receiving sensor; an optical assembly arranged on a side where a photosensitive surface of the receiving sensor is located. The optical assembly includes a first prism having a first end surface, a second end surface, and a plurality of sides connected between the first end surface and the second end surface. The plurality of sides include a first side and a second side. At least a portion of laser signals reflected by a detecting target is refracted by the first side and enter the first prism. At least a portion of laser signals refracted by the first side is refracted by the second side and emitted from the first prism to reach the receiving sensor.

Abstract: An interactive scenario implementation method includes: displaying, on a game scenario structure interface, one or more readable game scenario blocks. Each block represents one or more game scenarios that a player has played, and each block has a corresponding game scenario path data stored. The method also includes: determining, according to a scenario skipping instruction triggered by the player through the game scenario structure interface, a skip-origin block and a skip-destination block; updating, upon determining that the skip-origin block is located on a target game scenario path and that skip-origin game scenario path data of the skip-origin block and target game scenario path data of the skip-destination block have connectivity in the game logic, the target game scenario path data according to the skip-origin game scenario path data. A game scenario corresponding to the skip-destination block is entered according to the updated target game scenario path data.

Abstract: Disclosed is a die-bonding method which provides a target substrate having a circuit structure with multiple electrical contacts and multiple semiconductor elements each semiconductor element having a pair of electrodes, arranges the multiple semiconductor elements on the target substrate with the pair of electrodes of each semiconductor element aligned with two corresponding electrical contacts of the target substrate, and applies at least one energy beam to join and electrically connect the at least one pair of electrodes of every at least one of the multiple semiconductor elements and the corresponding electrical contacts aligned therewith in a heating cycle by heat carried by the at least one energy beam in the heating cycle. The die-bonding method delivers scattering heated dots over the target substrate to avoid warpage of PCB and ensures high bonding strength between the semiconductor elements and the circuit structure of the target substrate.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a roofing membrane, which may include a cap, a scrim, and a core. In some embodiments, the roofing system may also include an adhesive film, which may include a first adhesive layer adhered to the roofing membrane, a second adhesive layer configured to adhere the roofing membrane to a roofing substrate, and a barrier layer positioned between the first and second adhesive layers. Methods of manufacturing roofing systems are also disclosed.

Abstract: A nanonetwork with controlled chirality prepared via self-assembly of triblock terpolymers, wherein each of the triblock terpolymers includes a first block, a second block and a third block. The first block is connected to the second block, and the third block is connected to the second block. The first block, the second block and the third block are incompatible. The third block has a homochiral characteristic, and a chirality of the nanonetwork with controlled chirality is determined by the homochiral characteristic.

Abstract: Dynamic state-space modeling within a special purpose hardware platform to determine non-conversion risks for each trial user and churn risks for each active subscriber having exhibited a sequence of behaviors. The state-space model may be operable to determine a loss risk for each of a provider's active trial users and/or subscribers.

Abstract: The invention provides eTEC linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, immunogenic compositions comprising such glycoconjugates, and methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: Some embodiments relate to a roofing membrane. The roofing membrane comprises a scrim. The scrim has a top surface and a bottom surface. The roofing membrane comprises a cap layer on the top surface of the scrim. The cap layer comprises a first non-styrenic polypropylene polymer, a first polypropylene impact copolymer, and a first olefin block copolymer. The roofing membrane comprises a core layer on the bottom surface of the scrim. The core layer comprises a second non-styrenic polypropylene polymer, a second polypropylene impact copolymer, and a second olefin block copolymer. The roofing membrane is configured to prevent migration of at least one oil from a layer to the roofing membrane. Some embodiments relate to a roofing structure comprising the roofing membrane, a method for installing the roofing membrane, and the like.

Abstract: Some implementations described herein provide techniques and apparatuses for overcoming forces that may deflect an injector nozzle into an interior wall of a thin-film furnace. The implementations include a fixture that is coupled to the injector nozzle. The fixture is configurable to lock to a selected property of the injector nozzle to maintain, between a portion of the injector nozzle and the interior wall, a gap. In this way, the portion of the injector nozzle is prevented from colliding with the interior wall and dislodging particulates that may contaminate semiconductor product fabricated using the thin-film furnace.