Abstract: Embodiments of the present disclosure provide a method and a smart gas Internet of Things (IoT) system for remote control of an ultrasonic metering device. The method is implemented based on a smart gas device management platform of the IoT system and comprises: obtaining metering data of at least one ultrasonic metering device; determining any one of the at least one ultrasonic metering device as a current metering device; determining an accuracy of the current metering device through verifying the current metering device based on metering data of the current metering device and metering data of a related metering device; and sending an adjustment instruction to a target metering device based on the accuracy of at least one current metering device corresponding to the at least one ultrasonic metering device.

Abstract: The embodiments of the present disclosure provide a method for obtaining a natural gas energy metering component, including obtaining a temperature and pressure of a natural gas sample to be detected at a first site based on an object platform; obtaining sample data of a natural gas sample at a second site based on the object platform, the sample data including a natural gas component and a temperature and pressure of the natural gas component; obtaining sample data of a natural gas sample at the first site based on the object platform; determining a natural gas component of the natural gas sample to be detected at the first site based on sample data at the first site and the second site aggregated by a sensor network platform and the temperature and pressure of the natural gas sample to be detected at the first site.

Abstract: A method for managing energy-saving early warning of a smart gas flowmeter is provided. The method is executed by a smart gas management platform. The method comprises obtaining a remaining power of the smart gas flowmeter, determining a confidence level of the remaining power based on at least environmental data, determining a calibrated power by calibrating the remaining power based on the confidence level, determining whether to issue a power alert to a gas user based on the calibrated power, operation data of the smart gas flowmeter, and at least one reference correspondence. The reference correspondence represents a relationship between an operation behavior of the smart gas flowmeter and a power consumption. The method also comprises generating an energy-saving management and operation scheme of the smart gas flowmeter in response to a determination that the power alert is issued to the gas user.

Abstract: The embodiments of the present disclosure provide methods and systems for energy measuring based on natural gas data of a smart gas meter, including establishing the gas IoT. The object platform obtains consumed gas volume data and location data of the smart gas meter as first data and second data, and sending them to the management platform through the sensor network platform. The management platform generates consumed gas preprocessing data based on the first data and the second data, and generates energy measurement data after performing the computation outside the gas IoT on the consumed gas preprocessing data by the cloud platform outside the gas IoT. The management platform sends the energy measurement data to the user platform configured in a regional pipeline network center through the service platform. The user platform performs gas energy measurement of the smart gas meter based on the energy measurement data.

Abstract: The present disclosure provides an Industrial Internet of Things system for intelligent repair of manufacturing equipment and a control method. The Industrial Internet of Things system includes a management platform, a sensor network platform, and an object platform interacting in sequence. The object platform is configured as a plurality of manufacturing equipment arranged in sequence according to a process sequence on the assembly line. The management platform is configured to issue self-repair instructions and failure handling instructions corresponding to the intelligent repair method to the corresponding manufacturing equipment through the sensor network platform, so as to realize the automatic repair of manufacturing equipment, reduce the cost of manual troubleshooting, and ensure the normal production and manufacturing of the assembly line.

Abstract: A method for manufacturing a fixing belt for a wearable device, includes providing a flexible circuit board including a first area, a second area, and a pad in the first area; disposing an insulating layer on the flexible circuit board, the insulating layer being disposed in the second area; forming an electric conductive portion in the insulating layer; disposing a first protective layer and a second protective layer on opposite surfaces of the flexible circuit board, the electric conductive portion being between the flexible circuit board and the first protective layer; mounting an electronic component on the pad. A portion of the fixing belt containing the second area is a plug-in area, and the plug-in area is configured to be engaged with a device body of the wearable device, the electric conductive portion is disposed in the plug-in area.

Abstract: A method for determining a consistency coefficient of a power-law cement grout includes: determining a water-cement ratio of the power-law cement grout; according to engineering practice requirements, determining a time required to determine the consistency coefficient of the power-law cement grout; and obtaining the consistency coefficient of the power-law cement grout. The method is accurate and reliable, requires less calculation, etc.; and has very high practical value and popularization value in environmental protection and ecological restoration.

Abstract: The present invention belongs to the field of medicinal chemistry and relates to a class of substituted tricyclic compounds as PRMT5 inhibitors and the use thereof. Specifically, the present invention provides a compound represented by formula (A) or an isomer, pharmaceutically acceptable salt, solvate, crystal or prodrug thereof, a preparation method therefor, a pharmaceutical composition containing the compounds, and the use of the compounds or the composition for treating a disease mediated by PRMT5. The compounds of the present invention show significant inhibitory activity on PRMT5.

Abstract: An industrial internet of things system for intelligent production control is provided, comprising: a user platform, a service platform, a management platform, a sensor network platform, and an object platform. The user platform modifies production line parameters based on an instruction of the user, generates a first instruction, and sends it to the management platform through the transformation of the service platform. The object platform collects production link data of each production link of products and transmits it to the management platform. The management platform modifies work order parameters based on a second instruction transformed by the service platform, generates a third instruction, and determines whether devices corresponding to the plurality of production links are abnormal based on the production link data.

Abstract: The present disclosure provides a method and an Internet of Things system for managing a gas pressure based on smart gas. The method includes: determining a gas in-home pressure regulation scheme, and the gas in-home pressure regulation scheme including a pressure regulation parameter of a gas device; generating, based on the gas in-home pressure regulation scheme, a pressure regulation instruction; regulating, based on the pressure regulation instruction, a gas in-home pressure of at least one floor; and transmitting the gas in-home pressure regulation scheme to a smart gas user terminal.

Abstract: This provides pharmaceutical compositions that comprise a combination of an anti-cancer agent which is an first antibody and a second antibody. In some embodiments, the first antibody is an anti-Programmed Death-1 (PD-1) antibody. In certain embodiments, the composition is a fixed dose formulation. In certain embodiments, the composition is administered as a flat-dose. The disclosure also provides a kit for treating a subject afflicted with a disease, the kit comprising a dosage of any composition disclosed herein and instructions for using the composition in any of the disclosed methods for treating a disease.

Abstract: Methods and Internet of things systems for generating early warning information in a risk region in a smart city are provided. The method includes: obtaining, from at least one monitoring device of at least one target region based on a sensing network sub-platform of a sensing network platform, a monitoring image of the at least one target region by a public security management platform; sending the monitoring image of the corresponding target region to a management sub-platform of the public security management platform; and based on the management sub-platform, processing the monitoring image to determine a suspicious index of at least one person in the monitoring image; determining, based on a sum of suspicious group indexes of suspicious groups in the target region, a risk index of the target region; generating early warning information in response to the risk index of the target region greater than a first threshold.

Abstract: A photoelectric connector and a photoelectric adapter. The photoelectric connector includes: a housing assembly (1) including a front-rear run-through receiving space (11); a light guide assembly (2) including a tail handle (21), an insert core (22), and an optical fiber (23), the insert core (22) being disposed on one end of the tail handle (21), the tail handle (21) being disposed in the receiving space (11), and the optical fiber (23) being sequentially threaded into the tail handle (21) and the insert core (22); and a conductive assembly (3) including at least one conductive pin (31) and a cable (32) connected to the conductive pin (31); the conductive pin (31) and the insert core (22) being located on the same side of the receiving space (11); and the conductive pin (31) being disposed on the tail handle (21). The photoelectric connector and the photoelectric adapter may simplify a plugging operation.

Abstract: The present invention relates to a method for producing a bacterial microcompartment virus-like particle (VLP) carrying a cargo molecule, the method comprising introducing and expressing in a host cell or organism one or more polynucleotides comprising (a) a first sequence encoding bacterial microcompartment shell protomers and a second sequence encoding a cargo molecule fused to an encapsulation peptide comprising the sequence SKITGSSGNDTQGSLITYSGGARG, and forming a microcompartment that encapsulates the cargo molecule, or (b) a first sequence encoding bacterial microcompartment shell protomers and a second sequence encoding at least one of said protomers fused with a cargo molecule or a biochemical tag, and forming a microcompartment that expresses the cargo molecule or biochemical tag on an exterior surface. In one embodiment, the bacterial microcompartment protomers are CsoSIA and CsoS4A from Halothiobacillus neapolitanus, or HO-H, HO-P and HO-T1 from Haliangium ochraceum.

Abstract: The present disclosure discloses a method for liquid fermentation of black tea juice by using aged green tea and belongs to the technical field of tea leaf processing. The method comprises the following process steps: mixing aged green tea with hot water for a water bath-assisted extraction; adding a tannase into a crude catechin extract for a water bath-assisted enzymolysis; freeze-withering fresh tea leaves; homogenizing the freeze-withered leaves; pouring a homogenate into a primarily enzymolyzed crude catechin extract, adding a ?-glucosidase for secondary enzymolysis and performing fermentation; and treating a fermentation broth by microwave, and performing filtration and cooling to a room temperature.

Abstract: Embodiments of the present disclosure relate to methods, systems, and computer program products for event management. In a method, a token is obtained at a first agent device that is included in a network system, the token is for authenticating a first packet that is transmitted in the network system, and the first packet is generated according to a first network format. A second packet is generated based on the first packet and the token according to a second network format. The second packet is transmitted to a second agent device that is included in the network system, here both of the first and second agent devices support the first and second network formats. With these embodiments, the packet may be authenticated in a more effective way.

Abstract: This provides pharmaceutical compositions that comprise a combination of an anti-cancer agent which is an first antibody and a second antibody. In some embodiments, the first antibody is an anti-Programmed Death-1 (PD-1) antibody. In certain embodiments, the composition is a fixed dose formulation. In certain embodiments, the composition is administered as a flat-dose. The disclosure also provides a kit for treating a subject afflicted with a disease, the kit comprising a dosage of any composition disclosed herein and instructions for using the composition in any of the disclosed methods for treating a disease.

Abstract: Embodiments of the present disclosure relate to methods, systems, and computer program products for event management. In a method, a token is obtained at a first agent device that is included in a network system, the token is for authenticating a first packet that is transmitted in the network system, and the first packet is generated according to a first network format. A second packet is generated based on the first packet and the token according to a second network format. The second packet is transmitted to a second agent device that is included in the network system, here both of the first and second agent devices support the first and second network formats. With these embodiments, the packet may be authenticated in a more effective way.

Abstract: An antenna module includes an inner circuit board, an antenna circuit board, an outer circuit board, and at least one chip. The inner circuit board includes at least one inner wiring layer and at least one inner dielectric layer. The antenna circuit board includes at least one antenna structure. The antenna circuit board and the outer circuit board are disposed on opposite sides of the inner circuit board. The inner wiring layer comprises at least one inner pad. At least one first opening passing through the outer circuit board is defined to expose the inner pad. Each chip is received in one first opening and electrically connects to the inner pad. The antenna structure electrically connects to the chip through the inner wiring layer. A method for manufacturing such antenna module is also provided.

Abstract: A barbecue with spit functionality, the barbecue including: a barbecue body having a first opening and a second opening; a first spit support member mounted in the first opening and settable at a storage position, in which the first spit support member is substantially contained within the barbecue body, or one or more use positions, in which the first spit support member at least partially protrudes from the barbecue body; a second spit support member mounted in the second opening and settable at a storage position, in which the second spit support member is substantially contained within the barbecue body, or one or more use positions, in which the second spit support member at least partially protrudes from the barbecue body; and a spit rod releasably engageable with the first and second spit support members when the first and second spit support members are in their respective use positions.