Abstract: The present technology relates generally to oligolactic acid conjugates of paclitaxel, rapamycin, selumetinib, and other anticancer agents, micelle compositions containing such conjugates and methods of preparing and using such compositions to treat various cancers. Specifically, there are provided oligolactic acid conjugates wherein the oligolactic acid comprises 2 to 24 lactic acid subunits and is attached through an ester linkage to the oxygen of the 7-hydroxyl of the paclitaxel or paclitaxel derivative, the 40-hydroxyl of the rapamycin or rapamycin derivative, and the 2?-hydroxyl of the selumetinib or selumetinib derivative. Compositions comprising water and a micelle comprising a polylactic acid-containing polymer and the oligolactic acid conjugate may be readily prepared. Methods of inhibiting or killing cancer cells and treating paclitaxel, rapamycin, and/or selumetinib cancers are also provided.

Abstract: A portable electrical motor-driven exoskeleton ankle joint robot with gear transmission and control system which is intended to provide walking assistance in different speed and walking conditions to persons with disability in walking or muscle weakness or joint problem.

Abstract: An interactive exoskeleton robotic knee system for assist walking and gait training. The system comprises of an exoskeleton framework to be attached to the thigh and shank of the user's leg; electric motor; mechanical lock; motion sensor assembled on the lower limb unit, and a control box. The system provides extension and flexion movement in the knee joint.

Abstract: In various embodiments, a simple, robust molybdenum disulfide (MoS2) based photosensor is provided that is able to detect both light intensity and wavelength. The MoS2 based photosensor may be structured as a field effect transistor (FET) with a back-gate configuration, including MoS2 nanoflake layers, an insulating layer coated, doped substrate, and source, drain and backgate electrodes. The photoresponse of the MoS2 based photosensor exhibits a fast response component that is only weakly dependent on the wavelength of light incident on the sensor and a slow response component that is strongly dependent on the wavelength of light incident on the sensor. The fast response component alone may be analyzed to determine intensity of the light, while the slow response component may be analyzed to determine the wavelength of the light.

Abstract: Systems and method for peripheral cannulation are provided. Systems include cannulas defining fenestrations that can be exposed or occluded by a cover slip to selectively expose fenestrations to blood flow in an artery or vein.

Abstract: The present technology relates generally to oligolactic acid conjugates of paclitaxel, rapamycin, selumetinib, and other anticancer agents, micelle compositions containing such conjugates and methods of preparing and using such compositions to treat various cancers. Specifically, there are provided oligolactic acid conjugates wherein the oligolactic acid comprises 2 to 24 lactic acid subunits and is attached through an ester linkage to the oxygen of the 7-hydroxyl of the paclitaxel or paclitaxel derivative, the 40-hydroxyl of the rapamycin or rapamycin derivative, and the 2?-hydroxyl of the selumetinib or selumetinib derivative. Compositions comprising water and a micelle comprising a polylactic acid-containing polymer and the oligolactic acid conjugate may be readily prepared. Methods of inhibiting or killing cancer cells and treating paclitaxel, rapamycin, and/or selumetinib cancers are also provided.

Abstract: Systems and methods for robotic and exoskeleton hands are provided. An exoskeleton hand can include a flexible actuator having a cavity and a reinforcement band. The cavity can be filled with a fluid from a pressure source, forcing the actuator to deform, bend or extend. The fluid that fills the cavity as a driving force can be a gas or liquid, which can be recyclable or disposable.

Abstract: Systems and method for peripheral cannulation are provided. Systems include cannulas defining fenestrations that can be exposed or occluded by a cover slip to selectively expose fenestrations to blood flow in an artery or vein.

Abstract: According to various embodiments, a device may be provided. The device may include: a housing comprising a first engaging member; and a foot comprising a second engaging member. The first engaging member and the second engaging member may be configured to engage in at least one of a first way or a second way. When the first engaging member and the second engaging member engage in the first way, the housing may have a first orientation relative to a pre-determined portion of the foot. When the first engaging member and the second engaging member engage in the second way, the housing may have a second orientation relative to the pre-determined portion of the foot.

Abstract: The present invention provides a method for applying cloud-based time-lapse imaging systems. The method comprises a step for an camera device to receive a recording command, a step for the camera device to obtain a start time, an end time, and a time interval from the recording command, a step for the camera device to capture and upload still images to a cloud-based server at the time interval, a step for the cloud-based server to transfer the still images to a display device, and a step for the display device to present the still images as a time-lapse video.