Patents by Inventor Yue WEI

Yue WEI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Androgenic steroid compounds and a method of making and using the same
    Patent number: 5952319
    Abstract: An androgenic steroid compound of the formula: ##STR1## wherein: X, Y, Z, R.sup.1, R.sup.2, R.sup.3, R.sup.5 and R.sup.6 are as defined herein.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: September 14, 1999
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Yue-Wei Lee, Mansukh C. Wani
  • Method for treating alcohol dependence
    Patent number: 5783189
    Abstract: Isoflavonoids containing a carbon-carbon linked .beta.-D-glucose moiety at the C-8 position and isolated from the Chinese herbal plant Pueraria lobata are useful for treating alcohol dependence.
    Type: Grant
    Filed: April 23, 1996
    Date of Patent: July 21, 1998
    Assignee: Natural Pharmacia International, Inc.
    Inventors: Yue-Hu Pei, David Overstreet, Amir Hosein Rezvani, David Yue-Wei Lee
  • Derivatives of 2-nitro-imidazoles as hypoxic cell markers
    Patent number: 5674693
    Abstract: Derivatives of 2-nitro-imidazole, such as 1-(2-hydroxy-3-piperidinopropyl)-2-nitro-imidazole, are useful as hypoxic cell markers for immunochemical detection of hypoxia in tumor tissue.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: October 7, 1997
    Assignee: Natural Pharmacia International Inc.
    Inventors: James Arthur Raleigh, David Yue-Wei Lee
  • Hexahydroindenopyridine compounds having antispermatogenic activity
    Patent number: 5319084
    Abstract: Hexahydroindenopyridine compounds having the following formula and relative stereochemistry ##STR1## where R.sup.1 is C.sub.1-6 alkyl, R.sup.2 is hydrogen or C.sub.1-6 alkyl and R.sup.3 is carboxyl or a group which is metabolized to a carboxyl group under mammalian physiological conditions exhibit potent antispermatogenic activity and are useful in a method of inhibiting spermatogenesis in mammals.
    Type: Grant
    Filed: August 16, 1993
    Date of Patent: June 7, 1994
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, Yue-Wei Lee, Mansukh C. Wani, Patricia A. Fail, Joseph M. Jump
  • Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers
    Patent number: 5064823
    Abstract: Pentacyclic triterpenoid compounds such as .alpha. boswelic acid and its acetate, .beta.-boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are disclosed. Compositions based on the pentacyclic triterpenoid compounds which can be used to treat various cancers in mammals are also disclosed.
    Type: Grant
    Filed: May 1, 1990
    Date of Patent: November 12, 1991
    Assignee: Research Triangle Institute
    Inventors: Yue-Wei Lee, Qi-Cheng Fang, Zhen-Guo Wang, De-Hua Li, C. E. Cook