Patents by Inventor Yufan ZHANG
Yufan ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11648551Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, particularly an easy sample manipulation and/or a rapid change or a rapid thermal cycling of a sample temperature is needed (e.g. Polymerase Chain Reaction (PCR) for amplifying nucleic acids).Type: GrantFiled: December 12, 2018Date of Patent: May 16, 2023Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Ji Qi, Hua Tan, Yufan Zhang
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Publication number: 20230077906Abstract: The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).Type: ApplicationFiled: November 3, 2022Publication date: March 16, 2023Applicant: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
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Patent number: 11604148Abstract: A device and a method of using the device for improving sensitivity, speed, and easy-to-use of a colorimetric assay of a liquid sample are provided. The device includes a first plate and a second plate, spacers, and a textured surface. The two plates each have a sample contact surface and are movable relative to each other into an open configuration or a closed configuration. The sample is deposited on one or both plates in the open configuration. Thereafter, the closed configuration is formed where the plates compress at least part of the deposited sample into a continuous layer. The textured surface is disposed on the sample contact surface of the second plate and has a textured structure that scatters light, from which an optical signal such as a colorimetric or fluorescent signal can be obtained for analyzing the sample.Type: GrantFiled: February 9, 2018Date of Patent: March 14, 2023Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
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Patent number: 11567066Abstract: Among other things, the present disclosure is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly a homogeneous assay that does not use a wash step and that is fast (e.g., 60 seconds from dropping a sample to displaying results). The present disclosure is related to both competitive and non-competitive homogeneous assays.Type: GrantFiled: September 17, 2021Date of Patent: January 31, 2023Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Ji Li, Yufan Zhang
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Publication number: 20220407988Abstract: The present disclosure relates to devices, apparatus and methods of improving the accuracy of an image-based assay. One aspect of the present invention is to sandwich a sample between two plates and add reference marks in the sample areas of the plates, with at least one of the geometric and/optical properties of the reference marks being predetermined and known, and taking images of the sample with the reference marks, and applying a machine learning model in the analysis of the image-based assay.Type: ApplicationFiled: August 26, 2022Publication date: December 22, 2022Applicant: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi, Jun Tian, Wei Dong
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Patent number: 11523752Abstract: The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).Type: GrantFiled: February 16, 2018Date of Patent: December 13, 2022Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
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Publication number: 20220357307Abstract: An analyzer and a control method thereof, a detection system, and a storage medium are provided. The control method of the analyzer includes: determining whether the analyzer obtains an analysis parameter corresponding to a detection chip used for detection: requesting and obtaining the analysis parameter in a case of being determined that the analyzer does not obtain the analysis parameter; and performing detection on the detection chip and analyzing a substance to be analyzed contained in the detection chip by using the analysis parameter to obtain analysis data of the substance to be analyzed in a case of being determined that the analyzer obtains the analysis parameter.Type: ApplicationFiled: March 6, 2020Publication date: November 10, 2022Applicant: BOE Technology Group Co., Ltd.Inventors: Qin Qin, Jing Li, Yahua Yuan, Hongquan Li, Mengli Feng, Yufan Zhang, Jing Zhao
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Patent number: 11463608Abstract: The present disclosure relates to devices, apparatus and methods of improving the accuracy of an image-based assay. One aspect of the present invention is to sandwich a sample between two plates and add reference marks in the sample areas of the plates, with at least one of the geometric and/optical properties of the reference marks being predetermined and known, and taking images of the sample with the reference marks, and applying a machine learning model in the analysis of the image-based assay.Type: GrantFiled: February 18, 2021Date of Patent: October 4, 2022Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi, Jun Tian, Wei Dong
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Patent number: 11408028Abstract: Provided herein is a method and device for performing a homogeneous nucleic acid detection assay. The device can contain a pair of plates where one of the plates comprises (i) surface amplification surface; and (ii) target-specific nucleic acid probes that are immobilized on said amplification surface and that specifically binds to a part of the target nucleic acid; and the second plate comprises a sample contact area comprising a reagent storage site that comprises target-specific nucleic acid detection agents that specifically binds to another part of the target nucleic acid. In some embodiments, the device can be read without a washing unbound label from the surface of the device.Type: GrantFiled: February 8, 2018Date of Patent: August 9, 2022Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Ji Qi, Yufan Zhang, Ji Li
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Publication number: 20220241774Abstract: A detection chip and a detection system are provided. The detection chip includes a sample adding opening and at least one detection branch structure, each of the at least one detection branch structure includes a detection portion, the detection portion includes a detection groove and a reaction reagent, the detection groove is in connection with the sample adding opening, the reaction reagent is contained in the detection groove, and the detection portion is configured to allow optical detection to be performed on the reaction reagent in the detection groove.Type: ApplicationFiled: March 30, 2021Publication date: August 4, 2022Applicant: BOE Technology Group Co., Ltd.Inventors: Jing Zhao, Yufan Zhang, Chungen Yuan, Guangming An
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Publication number: 20220244231Abstract: A dairy solution analysis method and an electronic device thereof, a portable dairy solution analysis device and a computer-readable storage medium are disclosed. The dairy solution analysis method includes: detecting a test value of at least one indicator of a dairy solution with a test paper based on a colorimetric biochemical testing method; outputting an analysis result of the dairy solution based on the test value of the at least one indicator of the dairy solution.Type: ApplicationFiled: November 22, 2019Publication date: August 4, 2022Applicant: BOE Technology Group Co., Ltd.Inventors: Qin Qin, Yufan Zhang, Jing Li, Guangming An, Mengli Feng
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Publication number: 20220236149Abstract: The present invention relates to the methods, devices, and systems that make bio/chemical sensing (including, not limited to, immunoassay, nucleic assay, electrolyte analysis, etc.) faster, more sensitive, less steps, easy to perform, smaller amount of samples required, less or reduced (or no) needs for professional assistance, and/or lower cost, than many current sensing methods and devices. The present invention also allows a test performed by a smartphone.Type: ApplicationFiled: February 3, 2022Publication date: July 28, 2022Applicant: Essenlix CorporationInventors: Stephen Y. CHOU, Wei DING, Ji QI, Yufan ZHANG
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Publication number: 20220213536Abstract: Provided herein is a method and device for performing a homogeneous nucleic acid detection assay. The device can contain a pair of plates where one of the plates comprises (i) surface amplification surface; and (ii) target-specific nucleic acid probes that are immobilized on said amplification surface and that specifically binds to a part of the target nucleic acid; and the second plate comprises a sample contact area comprising a reagent storage site that comprises target-specific nucleic acid detection agents that specifically binds to another part of the target nucleic acid. In some embodiments, the device can be read without a washing unbound label from the surface of the device.Type: ApplicationFiled: March 22, 2022Publication date: July 7, 2022Applicant: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Ji Qi, Yufan Zhang, Ji Li
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Patent number: 11369968Abstract: The present invention provides devices, systems, and methods for rapid and easy-to-use in sample thermal cycling or temperature changes for the facilitation of reactions such as but not limited to PCR.Type: GrantFiled: January 15, 2021Date of Patent: June 28, 2022Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Hua Tan
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Publication number: 20220190226Abstract: A hydro-electrochemical power generator includes an interlayer having a first end and a second end opposite the first end, a first electrode in contact with the first end of the interlayer, wherein the first electrode includes a first material that is a corrodible metallic material, a second electrode in contact with the second end of the interlayer, wherein the second electrode includes a second material that is a corrodible metallic material, and at least one heat source coupled to one of the first electrode and the second electrode and configured to apply a temperature gradient across the first end and the second end of the interlayer, and wherein the first electrode and the second electrode are configured to output a non-zero electrical voltage in response to the application of the temperature gradient.Type: ApplicationFiled: December 14, 2021Publication date: June 16, 2022Applicant: The Texas A&M University SystemInventors: Choongho Yu, Yufan Zhang
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Publication number: 20220120740Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.Type: ApplicationFiled: December 15, 2021Publication date: April 21, 2022Applicant: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Ji Li, Yufan Zhang
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Patent number: 11274996Abstract: The present invention relates to the methods, devices, and systems that make bio/chemical sensing (including, not limited to, immunoassay, nucleic assay, electrolyte analysis, etc.) faster, more sensitive, less steps, easy to perform, smaller amount of samples required, less or reduced (or no) needs for professional assistance, and/or lower cost, than many current sensing methods and devices. The present invention also allow a test performed by a smartphone.Type: GrantFiled: February 7, 2018Date of Patent: March 15, 2022Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Ji Qi, Yufan Zhang
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Publication number: 20220062889Abstract: Disclosed are a detection chip, a preparation method and use method thereof, and a detection device. The detection chip comprises a substrate and a reservoir chamber. The reservoir chamber is configured to contain a liquid and comprises a support frame, and a first seal layer and a second seal layer for sealing the support frame. The support frame comprises a support frame body and a cavity formed in the middle of the support frame body. The second seal layer is configured to be concaved into the cavity. The substrate comprises a piercing structure.Type: ApplicationFiled: June 15, 2021Publication date: March 3, 2022Inventors: Chenyu WANG, Yufan ZHANG, Jing ZHAO
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Patent number: 11243201Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.Type: GrantFiled: August 1, 2018Date of Patent: February 8, 2022Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding, Ji Li, Yufan Zhang
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Publication number: 20220003757Abstract: Among other things, the present disclosure is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly a homogeneous assay that does not use a wash step and that is fast (e.g., 60 seconds from dropping a sample to displaying results). The present disclosure is related to both competitive and non-competitive homogeneous assays.Type: ApplicationFiled: September 17, 2021Publication date: January 6, 2022Applicant: Essenlix CorporationInventors: Stephen CHOU, Wei DING, Ji LI, Yufan ZHANG