Patents by Inventor Yufan ZHANG

Yufan ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Image-Based Assay Using Mark-Assisted Machine Learning
    Publication number: 20210392244
    Abstract: The present disclosure relates to devices, apparatus and methods of improving the accuracy of an image-based assay. One aspect of the present invention is to sandwich a sample between two plates and add reference marks in the sample areas of the plates, with at least one of the geometric and/optical properties of the reference marks being predetermined and known, and taking images of the sample with the reference marks, and applying a machine learning model in the analysis of the image-based assay.
    Type: Application
    Filed: February 18, 2021
    Publication date: December 16, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi, Jun Tian, Wei Dong
  • Homogeneous assay (II)
    Patent number: 11156606
    Abstract: Among other things, the present disclosure is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly a homogeneous assay that does not use a wash step and that is fast (e.g., 60 seconds from dropping a sample to displaying results). The present disclosure is related to both competitive and non-competitive homogeneous assays.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: October 26, 2021
    Assignee: Essenlix Corporation
    Inventors: Stephen Chou, Wei Ding, Ji Li, Yufan Zhang
  • ENHANCED, RAPID, HOMOGENEOUS, CELL STAINING AND ASSAY
    Publication number: 20210247317
    Abstract: The present invention provides, among other things, devices, kits, apparatus, and methods for rapid homogenous cell staining and imaging. Particularly, in some embodiments, the present invention can immunochemically stain a cell or a tissue in less than 60 seconds without washing. In some embodiments, the present invention stains and observers analyte (protein or nucleic acid) inside a cell in 60 seconds without wash.
    Type: Application
    Filed: August 23, 2019
    Publication date: August 12, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen CHOU, Wei DING, Ji LI, Shengjian Cai, Yufan Zhang, Jia Peng
  • ASSAY USING SAMPLE THICKNESS MULTIPLEXING
    Publication number: 20210162402
    Abstract: One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that are unavailable in using a single sample thickness.
    Type: Application
    Filed: August 16, 2019
    Publication date: June 3, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen CHOU, Wei DING, Ji Qi, Yufan Zhang
  • Homogeneous Assay
    Publication number: 20210140957
    Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly the homogeneous assay that does not use the step of wash and that is fast (e.g. 60 seconds from dropping a sample to displaying results).
    Type: Application
    Filed: June 12, 2018
    Publication date: May 13, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Li, Ji Qi, Jun Tian
  • MOLECULAR MANIPULATION AND ASSAY WITH CONTROLLED TEMPERATURE (II)
    Publication number: 20210138474
    Abstract: The present invention provides devices, systems, and methods for rapid and easy-to-use in sample thermal cycling or temperature changes for the facilitation of reactions such as but not limited to PCR.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 13, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Hua Tan
  • Assay with textured surface
    Patent number: 10966634
    Abstract: Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: April 6, 2021
    Assignee: ESSENLIX CORPORATION
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
  • Optics, device, and system for assaying
    Patent number: 10972641
    Abstract: The present invention provides, among other thing, devices and methods for simple, fast, and sensitive assaying, including imaging.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: April 6, 2021
    Assignee: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi, Jun Tian, Wei Dong
  • SAMPLE MANIPULATION AND ASSAY WITH RAPID TEMPERATURE CHANGE
    Publication number: 20210069709
    Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, particularly an easy sample manipulation and/or a rapid change or a rapid thermal cycling of a sample temperature is needed (e.g. Polymerase Chain Reaction (PCR) for amplifying nucleic acids).
    Type: Application
    Filed: December 12, 2018
    Publication date: March 11, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen CHOU, Wei DING, Ji QI, Hua Tan, Yufan Zhang
  • COMPRESSED OPEN FLOW ASSAY AND USE
    Publication number: 20210072122
    Abstract: The present invention relates to the methods, devices, and systems that make bio/chemical sensing (including, not limited to, immunoassay, nucleic assay, electrolyte analysis, etc.) faster, more sensitive, less steps, easy to perform, smaller amount of samples required, less or reduced (or no) needs for professional assistance, and/or lower cost, than many current sensing methods and devices. The present invention also allow a test performed by a smartphone.
    Type: Application
    Filed: February 7, 2018
    Publication date: March 11, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. CHOU, Wei DING, Ji QI, Yufan ZHANG
  • Molecular manipulation and assay with controlled temperature (II)
    Patent number: 10926265
    Abstract: The present invention provides devices, systems, and methods for rapid and easy-to-use in sample thermal cycling or temperature changes for the facilitation of reactions such as but not limited to PCR.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: February 23, 2021
    Assignee: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Hua Tan
  • ASSAY WITH TEXTURED SURFACE
    Publication number: 20210045658
    Abstract: Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.
    Type: Application
    Filed: September 9, 2020
    Publication date: February 18, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
  • SAMPLE COLLECTION AND HANDLING FOR DELAYED ANALYSIS
    Publication number: 20210018407
    Abstract: The present invention provides, among other things, devices, methods and applications of collecting, preserving, transporting, and analyzing tiny body fluids which have targeted biomarkers.
    Type: Application
    Filed: September 30, 2020
    Publication date: January 21, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen CHOU, Wei DING, Yufan Zhang, Ji Qi
  • ASSAYING CELLS AND NON-CELL ANALYTES IN A SAMPLE IN PARALLEL
    Publication number: 20210011001
    Abstract: Among other things, the present invention is related to bio/chemical sampling, sensing, assays and applications.
    Type: Application
    Filed: January 25, 2019
    Publication date: January 14, 2021
    Applicant: Essenlix Corporation
    Inventors: Stephen CHOU, Wei DING, Ji LI, Yufan Zhang
  • Q-MAX CARD-BASED ASSAY DEVICES AND METHODS
    Publication number: 20200406254
    Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, devices and methods of performing a biological and chemical extraction from a liquid, and performing assays, such as but not limited to immunoassays and nucleic acid assays.
    Type: Application
    Filed: February 13, 2018
    Publication date: December 31, 2020
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
  • MOLECULAR MANIPULATION AND ASSAY WITH CONTROLLED TEMPERATURE (II)
    Publication number: 20200376493
    Abstract: The present invention provides devices, systems, and methods for rapid and easy-to-use in sample thermal cycling or temperature changes for the facilitation of reactions such as but not limited to PCR.
    Type: Application
    Filed: April 23, 2018
    Publication date: December 3, 2020
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Hua Tan
  • SAMPLE COLLECTION, HOLDING AND ASSAYING
    Publication number: 20200363409
    Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.
    Type: Application
    Filed: August 1, 2018
    Publication date: November 19, 2020
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Ji Li, Yufan Zhang
  • HOMOGENOUS ASSAY (II)
    Publication number: 20200363408
    Abstract: Among other things, the present disclosure is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly a homogeneous assay that does not use a wash step and that is fast (e.g., 60 seconds from dropping a sample to displaying results). The present disclosure is related to both competitive and non-competitive homogeneous assays.
    Type: Application
    Filed: January 11, 2019
    Publication date: November 19, 2020
    Applicant: Essenlix Corporation
    Inventors: Stephen CHOU, Wei DING, Ji LI, Yufan ZHANG
  • Sample collection and handling for delayed analysis
    Patent number: 10823645
    Abstract: The present invention provides, among other things, devices, methods and applications of collecting, preserving, transporting, and analyzing tiny body fluids which have targeted biomarkers.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: November 3, 2020
    Assignee: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
  • QMAX ASSAYS AND APPLICATIONS
    Publication number: 20200319176
    Abstract: The present invention provides, among other things, QMAX card based assays in different forms for various analytes, offering simpler, fast, more sensitive assaying.
    Type: Application
    Filed: February 8, 2018
    Publication date: October 8, 2020
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi, Ji LI