Patents by Inventor Yuki Okumura
Yuki Okumura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11969990Abstract: There is provided an ink discharging apparatus including: a conveyor, a head, and a heater. The water-based ink for recording includes: a resin-dispersed pigment, resin fine particles of which glass transition temperature is not less than 33° C., water, and an organic solvent including a specific organic solvent of which saturation vapor pressure at 20° C. is not less than 0.03 hPa. The ink discharging apparatus satisfies the following condition (I): 6?(?/?)×1000?31. In the condition (I), ? (° C.) is the glass transition temperature of the resin fine particles, and ? (J/cm2) is an irradiation energy, radiated from the heater, per unit area of the recording medium.Type: GrantFiled: December 7, 2021Date of Patent: April 30, 2024Assignee: BROTHER KOGYO KABUSHIKI KAISHAInventor: Yuki Okumura
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Publication number: 20240087787Abstract: Disclosed herein is a coil component that includes a coil part embedded in a magnetic element body. The coil part has a structure in which plural interlayer insulating films and plural conductor layers having a coil pattern are alternately stacked. At least one of the conductor layers has a clearance area having no coil pattern and extending radially outward from a center axis of the coil part. The magnetic element body includes a first magnetic resin layer provided in an inner diameter area of the coil part, a second magnetic resin layer provided in a radially outside area of the coil part, and a fifth magnetic resin layer filled in the clearance area and contacting the first and second magnetic resin layers.Type: ApplicationFiled: September 8, 2023Publication date: March 14, 2024Inventors: Yuki HASHIMOTO, Toshiyuki ABE, Takeshi OKUMURA, Tomonaga NISHIKAWA, Naoaki FUJII, Kazuhiro YOSHIKAWA
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Publication number: 20230311511Abstract: A liquid discharging device includes: a cartridge mounting part configured to have a cartridge retaining a liquid mounted thereon; a head connected to the cartridge mounting part and configured to eject the liquid from a nozzle which is an opening provided on the nozzle surface of the head; and a discharge unit including a cap configured to cover the nozzle surface, the discharge unit being configured to discharge the liquid from the nozzle by creating a negative pressure in an internal space of the cap. The liquid is at least an ink, a storage liquid or a mixture thereof. The cartridge includes a first cartridge for retaining the ink and a second cartridge for retaining the storage liquid The ink includes a pigment, a resin microparticle, an organic solvent, a surfactant, and water. The storage liquid includes a water-soluble polymer, an organic solvent, a surfactant, and water.Type: ApplicationFiled: March 30, 2023Publication date: October 5, 2023Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventors: Yuki OKUMURA, Misaki TAKEUCHI
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Publication number: 20230311535Abstract: A liquid discharging device includes: a cartridge mounting part; a tank connected to the cartridge mounting part; a head that ejects a liquid; a discharge configured to discharge the liquid from the head; and a controller. The liquid is at least a storage liquid, a first liquid which is different from the storage liquid, or a mixture thereof. In a storage mode, the controller executes: a return process of returning the first liquid from the tank to a first liquid cartridge mounted on the cartridge mounting part; a first discharging process of discharging the first liquid from the head; a storage liquid supplying process for supplying a storage liquid from a storage liquid cartridge to the tank; and a second discharging process of discharging the storage liquid from the head, after executing the storage liquid supplying process.Type: ApplicationFiled: March 29, 2023Publication date: October 5, 2023Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventors: Yuki OKUMURA, Misaki TAKEUCHI
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Publication number: 20230248854Abstract: The production method of a radioactive metal-labeled antibody of the present invention includes a step of conducting a click reaction of a radioactive metal complex and an antibody site-specifically modified with a peptide to produce a radioactive metal-labeled antibody. The click reaction is performed between a first atomic group of the radioactive metal complex and a second atomic group directly or indirectly linked to the peptide. The second atomic group is an atomic group containing an azide group, or an atomic group containing trans-cyclooctene.Type: ApplicationFiled: October 16, 2020Publication date: August 10, 2023Applicant: NIHON MEDI-PHYSICS CO., LTD.Inventors: Akihiro IZAWA, Yu OGAWA, Hiroaki ICHIKAWA, Minoru KAWATANI, Hideaki TAKEMORI, Yuki OKUMURA
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Publication number: 20230090888Abstract: A recording method includes: discharging a water-based recording ink onto a recording medium to record an image, determining whether the recording medium is a coated paper or a non-coated paper; heating the recording medium or the water-based recording ink adhered to the recording medium with a cumulative heating amount Q1 when the recording medium is determined to be a coated paper; and with a cumulative heating amount Q2 smaller than the cumulative heating amount Q1 when the recording medium is determined to be a non-coated paper. The water-based recording ink includes: a resin dispersion pigment; a fine resin particle; a water-soluble organic compound; and water. A melting point of the water-soluble organic compound is within a range of 20 to 55° C. A viscosity of a 50 mass % aqueous solution of the water-soluble organic compound is 8.5 mPa·s or more at 20° C. and 90 mPa·s or less at 50° C.Type: ApplicationFiled: November 16, 2022Publication date: March 23, 2023Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventors: Hiroyuki TANAKA, Yuki OKUMURA
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Publication number: 20230083771Abstract: A recording method includes: recording a first image on a recording medium; reading the first image to determine whether the first image is correctly recorded; and when the first image is determined as not being correctly recorded, recording a second image over the first image. The water-based recording ink includes a water-soluble organic solvent which is at least one selected from the group consisting of a glycol ether and a diol compound having six to eight carbon atoms and two hydroxyl groups, at least one of the two hydroxyl groups not being bonded to a terminal of a carbon chain of the diol compound. A content of substances having a vapor pressure of 0.03 hPa or less at 20° C. in the water-based recording ink is 10 mass % or less and a surface tension of the water-based recording ink is 30 mN/m or less.Type: ApplicationFiled: November 16, 2022Publication date: March 16, 2023Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventors: Yuki OKUMURA, Hiroyuki TANAKA
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Publication number: 20220315780Abstract: A water-based ink for ink-jet recording includes: a pigment, acrylic-based resin particles, a surfactant, trimethylglycine, and water; wherein a glass transition temperature of the acrylic-based resin particles is not less than 25° C. and is less than 50° C.; and a static surface tension of the water-based ink for ink-jet recording is not more than 27 mN/m.Type: ApplicationFiled: March 8, 2022Publication date: October 6, 2022Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventors: Yuki OKUMURA, Harumitsu INOUE
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Publication number: 20220315784Abstract: A water-based ink for ink-jet recording includes: a pigment, resin particles, a solvent and water, wherein the resin particles are resin particles of an acrylic-based polymer; and a storage elastic modulus E at 25° C. of an ink film, of the water-based ink for ink-jet recording, which is dried and solidified is not less than 9.7×108 Pa.Type: ApplicationFiled: March 8, 2022Publication date: October 6, 2022Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventors: HARUMITSU INOUE, YUKI OKUMURA
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Patent number: 11318216Abstract: Provided is a method for producing a radiohalogen-labeled compound, the method comprises: a step in which a radiohalogen-labeling precursor compound (S-L) having a leaving group (L) capable of being nucleophilically substituted by a radioactive halide ion (X?) is subjected to a radiohalogenation reaction to obtain a reaction mixture RM1 which contains the radiohalogen-labeling precursor compound (S-L) and a reaction product (S—X) resulting from the radiohalogenation reaction; a step in which the reaction mixture RM1 is mixed with a polyvalent acid or a salt thereof to obtain a reaction mixture RM2; and a step in which the reaction product (S—X) is purified from the reaction mixture RM2 by a solid phase extraction method.Type: GrantFiled: May 28, 2018Date of Patent: May 3, 2022Assignee: NIHON MEDI-PHYSICS CO., LTD.Inventors: Yuki Okumura, Daisaku Nakamura, Masato Kiriu, Hiroaki Ichikawa, Gota Tonoya, Naomi Sugimoto
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Publication number: 20220119661Abstract: A water-based ink for ink-jet recording includes: a resin-dispersed pigment; resin fine particles of which glass transition temperature is not less than 22° C.; a humectant including a humectant component of which vapor pressure at 20° C. is not less than 0.02 hPa; and water. The water-based ink satisfies the following conditions (A) and (B): condition (A): 8.8??/??18.6, condition (B): 2.4??/??3.5; in the conditions (A) and (B): ?: a viscosity (mPa·s) at 25° C. of the water-based ink in a case that an evaporation rate obtained by a formula (1) is 0%, ?: a viscosity (mPa·s) at 25° C. of the water-based ink in a case that the evaporation rate obtained by the formula (1) is 50%, and ?: a viscosity (mPa·s) at 25° C. of the water-based ink in a case that the evaporation rate obtained by the formula (1) is 40%.Type: ApplicationFiled: November 11, 2021Publication date: April 21, 2022Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventor: Yuki OKUMURA
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Publication number: 20220088944Abstract: There is provided an ink discharging apparatus including: a conveyor, a head, and a heater. The water-based ink for recording includes: a resin-dispersed pigment, resin fine particles of which glass transition temperature is not less than 33° C., water, and an organic solvent including a specific organic solvent of which saturation vapor pressure at 20° C. is not less than 0.03 hPa. The ink discharging apparatus satisfies the following condition (I): 6?(?/?)×WO 1000?31. In the condition (I), ?(° C.) is the glass transition temperature of the resin fine particles, and ? (J/cm2) is an irradiation energy, radiated from the heater, per unit area of the recording medium.Type: ApplicationFiled: December 7, 2021Publication date: March 24, 2022Applicant: BROTHER KOGYO KABUSHIKI KAISHAInventor: YUKI OKUMURA
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Patent number: 11266753Abstract: Provided are a compound represented by the following formula (1): wherein X1 represents a hydrogen atom or a halogen atom, X2 represents a fluorine atom or a nitrile group, and X3 represents a radioactive halogen atom, or a salt thereof, and a medicament including the same.Type: GrantFiled: December 20, 2018Date of Patent: March 8, 2022Assignees: NIHON MEDI-PHYSICS CO., LTD., NATIONAL HOSPITAL ORGANIZATIONInventors: Akihiro Izawa, Yuki Okumura, Yurie Fukui, Hiroaki Ichikawa, Yoshifumi Maya, Miho Ikenaga, Hiroyuki Okudaira, Yoshihiro Doi, Mitsuhide Naruse
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Publication number: 20210060186Abstract: Provided are a compound represented by the following formula (1): wherein X1 represents a hydrogen atom or a halogen atom, X2 represents a fluorine atom or a nitrile group, and X3 represents a radioactive halogen atom, or a salt thereof, and a medicament including the same.Type: ApplicationFiled: December 20, 2018Publication date: March 4, 2021Applicants: Nihon Medi-Physics Co., Ltd., National Hospital OrganizationInventors: Akihiro IZAWA, Yuki OKUMURA, Yurie FUKUI, Hiroaki ICHIKAWA, Yoshifumi MAYA, Miho IKENAGA, Hiroyuki OKUDAIRA, Yoshihiro DOI, Mitsuhide NARUSE
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Patent number: 10894898Abstract: There is provided a water-based ink for ink-jet recording, including: a dye; water; and a compound represented by the following formula (1): wherein in the formula (1), X3 represents a group represented by the following formula (2) and Y3 represents a hydrogen atom, or the X3 represents a group represented by the following formula (3) and the Y3 is an ethyl group; and in the formula (2), R3 represents a straight-chain or branched-chain alkyl group having 12 to 14 carbons.Type: GrantFiled: December 21, 2017Date of Patent: January 19, 2021Assignee: Brother Kogyo Kabushiki KaishaInventor: Yuki Okumura
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Patent number: 10894779Abstract: The present invention provides a process to enhance the productivity such as yield of radioactive fluorine labeled flutemetamol. Provided is a process for producing a radioactive fluorine labeled flutemetamol, which comprises: (a) a step of allowing a labeling precursor represented by the predetermined general formula to react with a radioactive fluoride ion in a presence of a solvent to obtain a radioactive fluorine labeled intermediate represented by the predetermined general formula, and (b) a step of removing the protecting groups from the radioactive fluorine labeled intermediate to obtain a radioactive fluorine labeled flutemetamol, in which the above step (a) is carried out at an internal temperature of reaction solution of 140° C. or higher.Type: GrantFiled: February 22, 2018Date of Patent: January 19, 2021Assignee: GE HEALTHCARE LIMITEDInventors: Yuki Okumura, Gota Tonoya, Tomoyuki Matsunami, Kei Akama
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Publication number: 20200121811Abstract: Provided is a method for producing a radiohalogen-labeled compound, the method comprises: a step in which a radiohalogen-labeling precursor compound (S-L) having a leaving group (L) capable of being nucleophilically substituted by a radioactive halide ion (X?) is subjected to a radiohalogenation reaction to obtain a reaction mixture RM1 which contains the radiohalogen-labeling precursor compound (S-L) and a reaction product (S—X) resulting from the radiohalogenation reaction; a step in which the reaction mixture RM1 is mixed with a polyvalent acid or a salt thereof to obtain a reaction mixture RM2; and a step in which the reaction product (S—X) is purified from the reaction mixture RM2 by a solid phase extraction method.Type: ApplicationFiled: May 28, 2018Publication date: April 23, 2020Applicant: NIHON MEDI-PHYSICS CO., LTD.Inventors: Yuki OKUMURA, Daisaku NAKAMURA, Masato KIRIU, Hiroaki ICHIKAWA, Gota TONOYA, Naomi SUGIMOTO
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Publication number: 20200062724Abstract: The present invention provides a process to enhance the productivity such as yield of radioactive fluorine labeled flutemetamol. Provided is a process for producing a radioactive fluorine labeled flutemetamol, which comprises: (a) a step of allowing a labeling precursor represented by the predetermined general formula to react with a radioactive fluoride ion in a presence of a solvent to obtain a radioactive fluorine labeled intermediate represented by the predetermined general formula, and (b) a step of removing the protecting groups from the radioactive fluorine labeled intermediate to obtain a radioactive fluorine labeled flutemetamol, in which the above step (a) is carried out at an internal temperature of reaction solution of 140° C. or higher.Type: ApplicationFiled: February 22, 2018Publication date: February 27, 2020Inventors: Yuki OKUMURA, Gota TONOYA, Tomoyuki MATSUNAMI, Kei AKAMA
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Publication number: 20200009273Abstract: There is provided a labeling precursor compound represented by the general formula (2): wherein S represents a substrate, L represents a straight alkyl group having 1 to 6 carbon atoms which may contain an ether group, R1 and R2 each independently represent a straight or branched alkyl group having 1 to 30 carbon atoms, or a substituted or unsubstituted monocyclic or condensed polycyclic aryl group, R3 each independently represent an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms, and p represents an integer of 0 to 4.Type: ApplicationFiled: March 5, 2018Publication date: January 9, 2020Applicants: NIHON MEDI-PHYSICS CO., LTD., TOKYO INSTITUTE OF TECHNOLOGYInventors: Masato KIRIU, Hiroaki ICHIKAWA, Yuki OKUMURA, Hiroshi TANAKA
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Patent number: 10472338Abstract: Provided is a method for producing flutemetamol including the steps of: reacting a precursor compound represented by a predetermined general formula with a radioactive fluoride to obtain a 18F labeling compound represented by a predetermined general formula; allowing a strong base to act on the reaction mixture of the above step containing the precursor compound and the 18F labeling compound; after the above step, purifying the 18F labeling compound using a reverse phase solid phase extraction cartridge; and removing a protective group to obtain [18F]flutemetamol.Type: GrantFiled: October 17, 2016Date of Patent: November 12, 2019Assignees: GE HEALTHCARE LIMITED, NIHON MEDI-PHYSICS CO., LTD.Inventors: Yuki Okumura, Gota Tonoya, Tomoyuki Matsunami