Abstract: The present invention provides a process to enhance the productivity such as yield of radioactive fluorine labeled flutemetamol. Provided is a process for producing a radioactive fluorine labeled flutemetamol, which comprises: (a) a step of allowing a labeling precursor represented by the predetermined general formula to react with a radioactive fluoride ion in a presence of a solvent to obtain a radioactive fluorine labeled intermediate represented by the predetermined general formula, and (b) a step of removing the protecting groups from the radioactive fluorine labeled intermediate to obtain a radioactive fluorine labeled flutemetamol, in which the above step (a) is carried out at an internal temperature of reaction solution of 140° C. or higher.

Abstract: There is provided a labeling precursor compound represented by the general formula (2): wherein S represents a substrate, L represents a straight alkyl group having 1 to 6 carbon atoms which may contain an ether group, R1 and R2 each independently represent a straight or branched alkyl group having 1 to 30 carbon atoms, or a substituted or unsubstituted monocyclic or condensed polycyclic aryl group, R3 each independently represent an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms, and p represents an integer of 0 to 4.

Abstract: Provided is a method for producing flutemetamol including the steps of: reacting a precursor compound represented by a predetermined general formula with a radioactive fluoride to obtain a 18F labeling compound represented by a predetermined general formula; allowing a strong base to act on the reaction mixture of the above step containing the precursor compound and the 18F labeling compound; after the above step, purifying the 18F labeling compound using a reverse phase solid phase extraction cartridge; and removing a protective group to obtain [18F]flutemetamol.

Abstract: There is provided a water-based ink for ink-jet recording containing: water; at least one of quinacridone and a derivative thereof; and a dye represented by the following formula (1).

Abstract: Provided is a medicament comprising the compound represented by the following general formula (1) or a salt thereof: In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined. Methods for producing various radioactive compounds are also provided.

Abstract: Provided is a medicament comprising the compound represented by the following general formula (1) or a salt thereof: In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined. Methods for producing various radioactive compounds are also provided.

Abstract: Provided is a method for producing flutemetamol including the steps of: reacting a precursor compound represented by a predetermined general formula with a radioactive fluoride to obtain a 18F labeling compound represented by a predetermined general formula; allowing a strong base to act on the reaction mixture of the above step containing the precursor compound and the 18F labeling compound; after the above step, purifying the 18F labeling compound using a reverse phase solid phase extraction cartridge; and removing a protective group to obtain [18F]flutemetamol.

Abstract: A water-based ink for ink-jet recording includes: a pigment; water; polyoxypropylene methyl glucoside; and a compound represented by the formula (1): in the formula (1), R is a straight or branched chain alkyl group having 2 to 10 carbon atoms.

Abstract: Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined.

Abstract: There is provided a water-based ink for ink-jet recording, including: a dye; water; and a compound represented by the following formula (1): wherein in the formula (1), X3 represents a group represented by the following formula (2) and Y3 represents a hydrogen atom, or the X3 represents a group represented by the following formula (3) and the Y3 is an ethyl group; and in the formula (2), R3 represents a straight-chain or branched-chain alkyl group having 12 to 14 carbons.

Abstract: There is provided a water-based ink set for ink-jet recording, including: a water-based black ink containing a self-dispersible pigment, a water-soluble organic solvent of which vapor pressure is less than 1 Pa, and water; water-based color inks of two or more colors each containing a color pigment, a resin dispersant, a water-soluble organic solvent of which vapor pressure is less than 1 Pa, and water, wherein an average value of blending amounts of the water-soluble organic solvents in all of the water-based inks constituting the water-based ink set is in a range of 15% by weight to 35% by weight, and the water-based ink set satisfies the following condition X and condition Y, condition X: C?K?0.6 condition Y: A?1.5.

Abstract: A water-based ink for ink-jet recording includes: a pigment; water; a pigment dispersing resin including an ethylene oxide chain; and at least one of an anionic surfactant including an ethylene oxide group and a nonionic surfactant including an ethylene oxide group.

Abstract: There is provided a water-based ink for ink-jet recording containing: a pigment; a surfactant; and water, wherein dynamic surface tension of the water-based ink measured under a condition of temperature of 25 degrees Celsius and lifetime of 10 ms is not less than 35 mN/m; and dynamic surface tension of the water-based ink measured under a condition of temperature of 25 degrees Celsius and lifetime of 50 ms is not more than 34.5 mN/m.

Abstract: A water-based ink for ink-jet recording includes: a pigment; water; a first resin containing at least one of methacrylic acid and acrylic acid as a monomer; and a second resin, wherein the second resin is an ABA-type triblock copolymer which has a polymer block A composed only of methyl methacrylate and methacrylic acid and a polymer block B composed only of benzyl methacrylate and methacrylic acid; which has a weight average molecular weight of 3,000 to 30,000; which has an acid value of 90 mgKOH/g to 200 mgKOH/g; and which is partially or completely neutralized.

Abstract: A water-based ink for ink-jet recording includes: a pigment; water; oligoethylene glycol monoalkyl ether; and a water-soluble resin. The water-soluble resin is an ABA-type triblock copolymer which has a polymer block A composed only of methyl methacrylate and methacrylic acid and a polymer block B composed only of benzyl methacrylate and methacrylic acid; which has a weight average molecular weight of 3,000 to 30,000; which has an acid value of 90 mgKOH/g to 200 mgKOH/g; and which is partially or completely neutralized.

Abstract: There is provided a water-based ink set for ink-jet recording, including: a water-based black ink containing a self-dispersible pigment, a water-soluble organic solvent of which vapor pressure is less than 1 Pa, and water; water-based color inks of two or more colors each containing a color pigment, a resin dispersant, a water-soluble organic solvent of which vapor pressure is less than 1 Pa, and water, wherein an average value of blending amounts of the water-soluble organic solvents in all of the water-based inks constituting the water-based ink set is in a range of 15% by weight to 35% by weight, and the water-based ink set satisfies the following condition X and condition Y, condition X: C?K?0.6 condition Y: A?1.5.

Abstract: Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined.

Abstract: There is provided a water-based ink for ink-jet recording containing: water; at least one of quinacridone and a derivative thereof; and a dye represented by the following formula (1).

Abstract: A water-based ink for ink-jet recording includes: a pigment; water; a first resin containing at least one of methacrylic acid and acylic acid as a monomer; and a second resin, wherein the second resin is an ABA-type triblock copolymer which has a polymer block A composed only of methyl methacrylate and methacrylic acid and a polymer block B composed only of benzyl methacrylate and methacrylic acid; which has a weight average molecular weight of 3,000 to 30,000; which has an acid value of 90 mgKOH/g to 200 mgKOH/g; and which is partially or completely neutralized.

Abstract: A water-based ink for ink-jet recording includes: a pigment; water; oligoethylene glycol monoalkyl ether; and a water-soluble resin. The water-soluble resin is an ABA-type triblock copolymer which has a polymer block A composed only of methyl methacrylate and methacrylic acid and a polymer block B composed only of benzyl methacrylate and methacrylic acid; which has a weight average molecular weight of 3,000 to 30,000; which has an acid value of 90 mgKOH/g to 200 mgKOH/g; and which is partially or completely neutralized.