Abstract: A composition containing a docetaxel albumin nanoparticle. The composition contains docetaxel and an acid-denatured albumin, wherein the acid-denatured albumin is obtained by means of adding an acid to human serum albumin to adjust the pH value. The composition can be prepared into an injection or a freeze-dried powder injection. A composition with satisfactory physical and chemical stability is obtained by means of controlling the content of sodium octanoate in human serum albumin, preferably in an acid denaturation condition.

Abstract: A magnetic sensing device including a substrate having a supporting surface on which a first sensing area, a third sensing area, and a second sensing area are consecutively arranged in a direction of movement. The first, the second, and the third sensing areas are provided with a first midline, a second midline, and a third midline in the direction of movement, respectively. The first and second midlines are symmetrical with respect to the third midline. The first and second sensing areas are jointly configured to output a first output signal. The third sensing area is configured to output a second output signal. A phase difference between the first and second output signals is 90 degrees, and the first and second output signals are jointly configured to determine the distance or the speed or the angle of movement and the direction of movement of the relative motion.

Abstract: A battery connection structure includes a plurality of battery units connected in series. At least one battery unit is connected in series to other battery units through a temperature switch; the temperature switch includes a first connection member connected to a first electrode terminal of the battery unit and a second connection member connected to a second electrode terminal of the battery unit; at normal operating temperature, the first connection member and the second connection member are disconnected, and the first connection member and the second connection member are respectively connected to the two electrode terminals of the battery unit; when the temperature is higher than the normal operating temperature, the first connection member and/or the second connection member are/is deformed and disconnected from the corresponding electrode terminal(s) of the battery unit, and the first connection member and the second connection member are connected.

Abstract: A solar reflection full-band hyperspectral imaging detection system comprises a telescope light collection system, a field-of-view separation assembly, a spectrometer assembly, and a detector assembly. The field-of-view separation assembly comprises an integrated trisection field-of-view separator, a first field-of-view assembly, a second field-of-view assembly, and a third field-of-view assembly; the spectrometer assembly comprises a first spectrometer, a second spectrometer and a third spectrometer; and the detector assembly comprises a CMOS (Complementary Metal Oxide Semiconductor) detector, an InGaAs detector, and an HgCdTe detector. The present invention adopts the three-band spectrometer, and the spectrum aliasing, high photoelectric efficiency in the middle and low photoelectric efficiency at two ends, limited detection dynamic range, severe Etalon interference effect and the like of a two-band spectrometer with a traditional solar reflection full-band hyperspectral detection system are solved.

Abstract: The present application relates to particular anti-PAD4 (peptidyl arginine deiminase 4) antibodies, nucleic acids encoding the antibodies, vectors and host cells comprising the nucleic acids, and methods of making and using the antibodies.

Abstract: The invention provides a method for cargo sorting, configured to control an end effector with a package placement platform to sort the cargo, and the method includes: moving the package placement platform to a package obtaining position and obtaining the cargo to be sorted that enters into the package placement platform; moving the package placement platform to a package storage location; and exerting a first force to push the cargo into a package storage unit. With the help of the package placement platform, the method of the invention can receive the packages of different types or different sizes or different material so as to sort and transport all kinds of packages.

Abstract: A target tracking method is provided for a computer device. The method includes determining a target candidate region of a current image frame; capturing a target candidate image matching the target candidate region from the current image frame; determining a target region of the current image frame according to an image feature of the target candidate image; determining motion prediction data of a next image frame relative to the current image frame by using a motion prediction model and according to the image feature of the target candidate image; and determining a target candidate region of the next image frame according to the target region and the motion prediction data.

Abstract: The present application provides a method for analyzing droplets on the basis of volume distribution including obtaining a total volume V of a sample containing target molecules based on a system prepared using the sample. The system is emulsified into droplets. A droplet system is obtained when the droplets obtaining the sample executes an amplification reaction. A droplet image of the droplet system is obtained. A total number n of droplets included in the droplet system is obtained based on the droplet image. A droplet volume distribution of the droplet system is obtained based on the droplet image. A number j of negative droplets among the n droplets is counted. A quantitative analysis is performed for the target molecules according to the total volume V of the sample, the total number n of droplets, the droplet volume distribution information, and the number j of negative droplets.

Abstract: Embodiments of the present disclosure relate to lipid-PEGylated solid support and phosphoramidites derivatives, methods for preparing the same, and their uses in the delivery of oligonucleotide drugs to the cellular targets.

Abstract: The present disclosure provides a method (100) in a network node advertising a Binding Segment Identifier, BSID. The method (100) includes: receiving (110) a first echo request packet containing a first target Forwarding Equivalence Class, FEC, stack including an FEC associated with the BSID; and transmitting (120), in response to a Time To Live, TTL, expiration associated with the first echo request packet, a first echo reply packet to an initiating network node initiating the first echo request packet, the first echo reply packet containing an indicator indicating that the FEC is to be replaced by a set of FECs.

Abstract: The present disclosure provides an isolated recombinant oncolytic adenovirus, a pharmaceutical composition, and uses thereof for drugs for treatment of tumors and/or cancers. The recombinant oncolytic adenovirus is a selectively replicating oncolytic adenovirus, and the genome of the recombinant oncolytic adenovirus is integrated with a coding sequence of exogenous shRNA capable of inhibiting PDL1 expression in tumor cells. The replication capability of the virus in normal primary cells is much lower than the replication capability of the virus in tumor cells. Moreover, the expressed shPDL1 can significantly reduce the level of PDL1 protein highly expressed in tumor cells. Thus, the oncolytic killing effect of the oncolytic virus and the anti-tumor immunostimulatory effect of immune cells produce a synergistic effect.

Abstract: The present disclosure concerns synthesis, anion binding features, liquid-liquid extraction of salts, and anti-corrosion character of aryl-triazole bicyclic macrocycles of Formula (I) and related compounds:

Abstract: A substrate includes a driving backplane, a plurality of first connecting lines and a plurality of second connecting lines. The driving backplane includes a base substrate, at least one first lead group and at least one second lead group. Each first lead group includes a plurality of first leads, and each second lead group includes a plurality of second leads. A first lead group and a corresponding second lead group is disposed in a peripheral region. The plurality of first connecting lines are disposed on at least one side face of the driving backplane, each first connecting line is electrically connected to at least one first lead. The plurality of second connecting lines are disposed on the at least one side face of the driving backplane, each second connecting line is electrically connected to at least one second lead, and is in contact with a corresponding first connecting line.

Abstract: The present application relates to a pregabalin sustained release composition, comprising: (a) an active ingredient; (b) a matrix-forming agent; (c) a swelling agent; (d) a gelling agent; and optionally a filler. The pregabalin sustained release composition provided in the present application can rapidly swell in volume when exposed to aqueous medium until exceeding the dimeter of human gastric pyloric (13 mm). It thereby prolongs the gastric emptying time to increase the retention time of pregabalin in the stomach and enhances absorption of pregabalin in the small intestine and ascending colon. Moreover, the pregabalin sustained release composition provided herein achieves a sustained release for 24 h, which allows QD (once a day) administration, reduces administration number, and improves patient compliance.

Abstract: The present invention discloses a fabrication method and use of a ?40 mm large-size and high-contrast fiber optic image inverter, belonging to the field of manufacturing of fiber optic imaging elements. The light-absorbing glass for preparing the ?40 mm large-size and high-contrast fiber optic image inverter consists of the following components in molar percentage: SiO2 60-69.9, Al2O3 1.0-10.0, B2O3 10.1-15.0, Na2O 1.0-8.0, K2O 3.0-10.0, MgO 0.1-1.0, CaO 0.5-5.0, ZnO 0-0.1, TiO2 0-0.1, ZrO2 0.1-1.0, Fe2O3 3.0-6.5, Co2O3 0.1-0.5, V2O5 0.51-1.5 and MoO3 0.1-1.0. The fiber optic image inverter has the advantages of low crosstalk of stray light, high resolution and high contrast.

Abstract: An avalanche photodiode (APD) includes a first electrode, a substrate layer, a buffer layer, a gain layer, a gradient layer, an absorption layer, a diffusion barrier layer, a contact layer, and a second electrode. The gain layer, the gradient layer, and the absorption layer are arranged vertically in sequence. The gain layer, the gradient layer, and the absorption layer are located between the buffer layer and the diffusion barrier layer. The gain layer includes at least two gain units, and the gain units are arranged in a stacked manner. Each of the gain units includes a multiplication layer and a charge layer that are arranged vertically. A distance between the charge layer and the gradient layer is less than a distance between the multiplication layer and the gradient layer.

Abstract: The present invention discloses a 400 MPa corrosion-resistant steel bar and a production method thereof. The steel bar includes the following chemical ingredients: 9.5-10.4% of Cr, 1.0-1.2% of Mo, 0.3-0.6% of Mn, 0.01-1% of Ni, 0.01-0.5% of Cu, at most 0.014% of C, at most 0.004% of N, 0.01-0.05% of Nb, 0.2-0.6% of Si, and the balance of Fe, where Cr+Mo+0.5Mn+0.35Ni+0.25Cu is 11.1-12.2%, and C+N+0.3Si+Mn+1.8Nb is 0.4-0.8%.

Abstract: A display panel, a manufacturing method thereof, and a display terminal are provided. The display panel includes a substrate layer, an anode layer, a pixel separating layer, an organic light-emitting layer, and a cathode layer. The pixel separating layer includes a plurality of pixel opening regions and a non-opening region disposed between two adjacent pixel opening regions. The cathode layer includes at least one via hole corresponding to the non-opening region of the pixel separating layer.

Abstract: The present application relates to the technical field of polyaryletherketone, and discloses a preparation method for a coating material containing high-temperature self-crosslinking fluorine-containing polyaryletherketone. A molecular chain of the high-temperature self-crosslinking fluorine-containing polyaryletherketone contains two crosslinking groups of a styrene group and a thioether group, and its structural formula is: Herein, the value range of m is 1-40%, the value range of n is 60-99%, and R is a group that removes a phenolic hydroxyl group from hexafluorobisphenol A. In the high-temperature curing process after film coating, the crosslinking reaction occurs to form a crosslinked polymer coating layer, thereby a coating surface with good moisture and heat resistance, wear resistance, and low friction coefficient is formed.

Abstract: A short-term traffic flow prediction method based on a causal gated-low-pass graph convolutional network can include constructing a causal gated-low-pass graph convolutional network, where the causal gated-low-pass graph convolutional network includes a causal gated-low-pass convolutional block. The causal gated-low-pass convolutional block is connected to a fully-connected output layer, the causal gated-low-pass convolutional block includes two causal gated linear units and a low-pass graph convolutional block, and the low-pass graph convolutional block is set between the causal gated linear units. The method can further include obtaining a traffic flow network diagram and a traffic flow value based on traffic flow data, using the traffic flow network diagram as input, and performing short-term traffic flow prediction by using the causal gated-low-pass graph convolutional network. The method can predict short-term traffic flow with high accuracy.