Patents by Inventor Zhenxue Jing

Zhenxue Jing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11191502
    Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: December 7, 2021
    Assignee: Hologic, Inc.
    Inventors: Andrew P. Smith, Jay A. Stein, Ken Defreitas, Ian Shaw, Zhenxue Jing, Loren Niklason, Baorui Ren, Christopher Ruth
  • Patent number: 11090017
    Abstract: Methods and systems for medical imaging including synthesizing virtual projections from acquired real projections and generating reconstruction models and images based on the synthesized virtual projections and acquired real projections. For example, first x-ray imaging data is generated from a detected first x-ray emission at a first angular location and second x-ray imaging data is generated from a detected second x-ray emission at a second angular location. Based on at least the first x-ray imaging data and the second x-ray imaging data, third x-ray imaging data for a third angular location relative to the breast may be synthesized. An image of the breast may be displayed or generated from the third x-ray imaging data.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: August 17, 2021
    Assignee: Hologic, Inc.
    Inventors: Yiheng Zhang, Zhenxue Jing, Christopher Ruth
  • Publication number: 20210204894
    Abstract: A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.
    Type: Application
    Filed: February 12, 2021
    Publication date: July 8, 2021
    Inventors: Baorui Ren, Andrew P. Smith, Zhenxue Jing, Jay Stein, Kenneth F. Defreitas
  • Publication number: 20210113168
    Abstract: Systems and methods for breast x-ray tomosynthesis that enhance spatial resolution in the direction in which the breast is flattened for examination. In addition to x-ray data acquisition of 2D projection tomosynthesis images ETp1 over a shorter source trajectory similar to known breast tomosynthesis, supplemental 2D images ETp2 are taken over a longer source trajectory and the two sets of projection images are processed into breast slice images ETr that exhibit enhanced spatial resolution, including in the thickness direction of the breast. Additional features include breast CT of an upright patient's flattened breast, multi-mode tomosynthesis, and shielding the patient from moving equipment.
    Type: Application
    Filed: September 1, 2020
    Publication date: April 22, 2021
    Applicant: Hologic, Inc.
    Inventors: Andrew P. SMITH, Jay STEIN, Kenneth DEFREITAS, Ian SHAW, Zhenxue JING, Loren NIKLASON, Baorui REN, Christopher RUTH
  • Patent number: 10959694
    Abstract: A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: March 30, 2021
    Assignee: HOLOGIC, INC.
    Inventors: Zhenxue Jing, Georgia Hitzke, Donald Kennedy, Andrew Smith, Jay A. Stein
  • Patent number: 10952692
    Abstract: A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: March 23, 2021
    Assignee: Hologic, Inc.
    Inventors: Baorui Ren, Andrew P. Smith, Zhenxue Jing, Jay Stein, Kenneth F. Defreitas
  • Publication number: 20210035680
    Abstract: Examples of the present disclosure describe systems and methods for automating clinical workflow decisions. In aspects, patient data may be collected from multiple data sources, such as patient records, imaging data, etc. The patient data may be processed using an artificial intelligence (AI) component. The output of the AI component may be used by healthcare professionals to inform healthcare decisions for patients. The output of the AI component and additional information relating to the healthcare decisions and healthcare paths may be provided as input to a decision analysis component. The decision analysis component may process the input and output an automated healthcare recommendation that may be used to further inform the healthcare decisions of the healthcare professionals. In some aspects, the output of the decision analysis component may be used to determine a priority or timeline for performing one or more actions relating to patient healthcare.
    Type: Application
    Filed: July 31, 2020
    Publication date: February 4, 2021
    Inventors: Biao CHEN, Zhenxue JING, Ashwini KSHIRSAGAR, Nikolaos GKANATSIOS, Haili CHUI
  • Publication number: 20210015435
    Abstract: While performing a tomosynthesis procedure, the breast of a patient is compressed between two compression elements to create an imaging condition. Foam is secured to the rigid substrate of a one of the compression elements. The patient's chest wall is aligned with the leading edge surface of the foam. The inner side of the breast is disposed proximate the lateral edge surface of the foam and the outer side of the breast is disposed proximate the outer lateral edge surface of the foam. A mid-plane is disposed between the inner and outer lateral edge surfaces of the foam. An interface connects a leading edge surface of the foam and compressive surfaces. A portion of the leading edge surface which is aligned with the mid-plane is incompletely compressed.
    Type: Application
    Filed: May 24, 2019
    Publication date: January 21, 2021
    Inventors: Kenneth F. DEFREITAS, Alan REGO, Richard Gladwin EDWARDS, Christine JANSSEN, Zhenxue JING, Jay A. STEIN, Diane CONLIN, Timothy N. WELLS, Cornell Lee WILLIAMS
  • Patent number: 10792003
    Abstract: Systems and methods for breast x-ray tomosynthesis that enhance spatial resolution in the direction in which the breast is flattened for examination. In addition to x-ray data acquisition of 2D projection tomosynthesis images ETp1 over a shorter source trajectory similar to known breast tomosynthesis, supplemental 2D images ETp2 are taken over a longer source trajectory and the two sets of projection images are processed into breast slice images ETr that exhibit enhanced spatial resolution, including in the thickness direction of the breast. Additional features include breast CT of an upright patient's flattened breast, multi-mode tomosynthesis, and shielding the patient from moving equipment.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: October 6, 2020
    Assignee: Hologic, Inc.
    Inventors: Andrew P. Smith, Jay A. Stein, Ken Defreitas, Ian Shaw, Zhenxue Jing, Loren Niklason, Baorui Ren, Christopher Ruth
  • Publication number: 20200184262
    Abstract: A method and system for creating a dynamic self-learning medical image network system, wherein the method includes receiving, from a first node initial user interaction data pertaining to one or more user interactions with the one or more initially obtained medical images; training a deep learning algorithm based at least in part on the initial user interaction data received from the node; and transmitting an instance of the trained deep learning algorithm to the first node and/or to one or more additional nodes, wherein at each respective node to which the instance of the trained deep learning algorithm is transmitted, the trained deep learning algorithm is applied to respective one or more subsequently obtained medical images in order to obtain a result.
    Type: Application
    Filed: May 31, 2018
    Publication date: June 11, 2020
    Inventors: Haili Chui, Zhenxue Jing
  • Publication number: 20200146644
    Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
    Type: Application
    Filed: December 19, 2019
    Publication date: May 14, 2020
    Inventors: Andrew P. SMITH, Jay A. STEIN, Ken DEFREITAS, Ian SHAW, Zhenxue JING, Loren NIKLASON, Baorui REN, Christopher RUTH
  • Publication number: 20200085393
    Abstract: Methods and systems for medical imaging including synthesizing virtual projections from acquired real projections and generating reconstruction models and images based on the synthesized virtual projections and acquired real projections. For example, first x-ray imaging data is generated from a detected first x-ray emission at a first angular location and second x-ray imaging data is generated from a detected second x-ray emission at a second angular location. Based on at least the first x-ray imaging data and the second x-ray imaging data, third x-ray imaging data for a third angular location relative to the breast may be synthesized. An image of the breast may be displayed or generated from the third x-ray imaging data.
    Type: Application
    Filed: September 11, 2019
    Publication date: March 19, 2020
    Applicant: Hologic, Inc.
    Inventors: Yiheng Zhang, Zhenxue Jing, Christopher Ruth
  • Publication number: 20200069273
    Abstract: Techniques for patient positioning quality assurance prior to mammographic image acquisition are described. A system may include an x-ray source configured to expose human tissue to radiation. An x-ray detector module may be configured to detect the radiation and generate a pre-diagnostic image of the human tissue. A position analysis module may be configured to receive the pre-diagnostic image and determine whether the human tissue is positioned correctly based upon one or more predefined positioning criteria. A non-transitory computer-readable storage medium may be configured to store the results of the positional analysis module determination. A display may be configured to display the determination of the position analysis module within a user interface. Other embodiments are described and claimed.
    Type: Application
    Filed: March 15, 2018
    Publication date: March 5, 2020
    Applicant: HOLOGIC, INC.
    Inventors: Brad Michael KELLER, Zhenxue JING
  • Patent number: 10575804
    Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: March 3, 2020
    Assignee: HOLOGIC, INC.
    Inventors: Andrew P. Smith, Jay A. Stein, Ken Defreitas, Ian Shaw, Zhenxue Jing, Loren Niklason, Baorui Ren, Christopher Ruth
  • Patent number: 10561387
    Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: February 18, 2020
    Assignee: HOLOGIC, INC.
    Inventors: Andrew P. Smith, Jay A. Stein, Ken Defreitas, Ian Shaw, Zhenxue Jing, Loren Niklason, Baorui Ren, Christopher Ruth
  • Publication number: 20200022663
    Abstract: A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.
    Type: Application
    Filed: July 18, 2019
    Publication date: January 23, 2020
    Inventors: Baorui Ren, Andrew P. Smith, Zhenxue Jing, Jay Stein, Kenneth F. Defreitas
  • Publication number: 20190290221
    Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
    Type: Application
    Filed: June 12, 2019
    Publication date: September 26, 2019
    Applicant: Hologic, Inc.
    Inventors: Andrew P. Smith, Jay A. Stein, Zhenxue Jing, Baorui Ren, Loren Niklason, Christopher Ruth, Ian Shaw
  • Patent number: 10413255
    Abstract: A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: September 17, 2019
    Assignee: HOLOGIC, INC.
    Inventors: Jay Stein, Andrew P. Smith, Zhenxue Jing, Loren Niklason
  • Patent number: 10398398
    Abstract: A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: September 3, 2019
    Assignee: HOLOGIC, INC.
    Inventors: Baorui Ren, Andrew P. Smith, Zhenxue Jing, Jay Stein, Kenneth F. Defreitas
  • Patent number: 10357211
    Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: July 23, 2019
    Assignee: HOLOGIC, INC.
    Inventors: Andrew P. Smith, Jay A. Stein, Zhenxue Jing, Baorui Ren, Loren Niklason, Christopher Ruth, Ian Shaw