Patents by Inventor Zhenxue Jing

Zhenxue Jing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150327826
    Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
    Type: Application
    Filed: April 24, 2015
    Publication date: November 19, 2015
    Applicant: HOLOGIC, INC.
    Inventors: Andrew P. Smith, Jay A. Stein, Zhenxue Jing, Baorui Ren, Loren Niklason, Christopher Ruth, Ian Shaw
  • Patent number: 9119593
    Abstract: A multi-mode tomosynthesis/mammography system and method in which a mammography gain map is used to gain correct mammographic images of a patient's breast but enhanced gain maps for respective projection angled are used to correct tomosynthesis images acquired with the same system.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: September 1, 2015
    Assignee: HOLOGIC, INC.
    Inventors: Baorui Ren, Andrew P. Smith, Zhenxue Jing, Jay Stein
  • Publication number: 20150157288
    Abstract: The effects of patient motion in tomosynthesis scan images are automatically detected and quantified. In at least one embodiment an indication of detection of the effects of patient motion in tomosynthesis scan images is provided shortly after the scan, e.g., before the patient is discharged or before the breast is decompressed. A patient motion score may be calculated as part of motion quantification. The score may be stored for subsequent retrieval. Images may be presented with reference features to help a technician confirm of the effects of motion in images.
    Type: Application
    Filed: August 4, 2011
    Publication date: June 11, 2015
    Inventors: Baorui Ren, Loren Niklason, Andrew Smith, Zhenxue Jing, Jay Stein
  • Patent number: 9020579
    Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: April 28, 2015
    Assignee: Hologic, Inc.
    Inventors: Andrew P. Smith, Jay A. Stein, Zhenxue Jing, Baorui Ren, Loren Niklason, Christopher Ruth, Ian Shaw
  • Publication number: 20140376690
    Abstract: A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view.
    Type: Application
    Filed: September 8, 2014
    Publication date: December 25, 2014
    Inventors: Zhenxue JING, Georgia HITZKE, Donald KENNEDY, Andrew SMITH, Jay A. STEIN
  • Publication number: 20140321607
    Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
    Type: Application
    Filed: July 14, 2014
    Publication date: October 30, 2014
    Applicant: Hologic, Inc.
    Inventors: Andrew P. SMITH, Jay A. STEIN, Ken DEFREITAS, Ian SHAW, Zhenxue JING, Loren NIKLASON, Baorui REN, Christopher RUTH
  • Patent number: 8873716
    Abstract: An x-ray tube is described that includes components for increasing x-ray image clarity in the presence of a moving x-ray source by modifying focal spot characteristics, including focal spot size and focal spot position. In a first arrangement a static focal spot is moved in a direction contrary to the movement of the x-ray source so that an effective focal spot position is essentially fixed in space relative to one of the imaged object and/or detector during a tomosynthesis exposure. In a second arrangement, the size of the static focal spot is increased, and the resulting increase in tube current reduces the exposure time and concomitant blur effect. The methods may be used alone or in combination; for example an x-ray tube with a larger, moveable static focal spot will result in a system that fully utilizes the x-ray tube generator, provides a high quality image with reduced blur and, due to the decrease in exposure time, may scan the patient more quickly.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: October 28, 2014
    Inventors: Baorui Ren, Jay Stein, Zhenxue Jing, Andrew Smith
  • Publication number: 20140314198
    Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.
    Type: Application
    Filed: June 30, 2014
    Publication date: October 23, 2014
    Inventors: Baorui Ren, Andrew P. Smith, Thomas Farbizio, Zhenxue Jing, Jay Stein
  • Patent number: 8831171
    Abstract: A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: September 9, 2014
    Assignee: Hologic, Inc.
    Inventors: Zhenxue Jing, Georgia Hitzke, Donald Kennedy, Andrew Smith, Jay A. Stein
  • Patent number: 8787522
    Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: July 22, 2014
    Assignee: Hologic, Inc
    Inventors: Andrew P. Smith, Jay A. Stein, Ken Defreitas, Ian Shaw, Zhenxue Jing, Loren Niklason, Baorui Ren, Christopher Ruth
  • Patent number: 8768026
    Abstract: A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: July 1, 2014
    Assignee: Hologic, Inc.
    Inventors: Baorui Ren, Andrew P. Smith, Zhenxue Jing, Jay A. Stein, Kenneth F. DeFreitas
  • Patent number: 8767911
    Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: July 1, 2014
    Assignee: Hologic, Inc.
    Inventors: Baorui Ren, Andrew P Smith, Thomas Farbizio, Zhenxue Jing, Jay Stein
  • Publication number: 20140044230
    Abstract: A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.
    Type: Application
    Filed: October 18, 2013
    Publication date: February 13, 2014
    Applicant: Hologic, Inc.
    Inventors: Jay Stein, Andrew P. Smith, Zhenxue Jing, Loren Niklason
  • Publication number: 20140016737
    Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.
    Type: Application
    Filed: August 14, 2013
    Publication date: January 16, 2014
    Applicant: Hologic, Inc.
    Inventors: Baorui Ren, Andrew P. Smith, Thomas Farbizio, Zhenxue Jing, Jay Stein
  • Patent number: 8592772
    Abstract: An integrated tomosynthesis/molecular breast imaging device having improved sensitivity includes tomosynthesis imaging components and molecular breast imaging components. The imaging components may be used individually or in combination to provide a system with improved sensitivity and specificity. Molecular imaging components may be smoothly advanced or withdrawn depending upon the desired imaging mode. The system supports both PET and SPECT imaging and enables SPECT collimation to be modified in accordance with image capture requirements.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: November 26, 2013
    Assignee: Hologic, Inc.
    Inventors: Jay Stein, Baorui Ren, Andrew P. Smith, Ken Brooks, Zhenxue Jing, Ian Shaw, Kenneth DeFreitas
  • Publication number: 20130259192
    Abstract: An x-ray tube is described that includes components for increasing x-ray image clarity in the presence of a moving x-ray source by modifying focal spot characteristics, including focal spot size and focal spot position. In a first arrangement a static focal spot is moved in a direction contrary to the movement of the x-ray source so that an effective focal spot position is essentially fixed in space relative to one of the imaged object and/or detector during a tomosynthesis exposure. In a second arrangement, the size of the static focal spot is increased, and the resulting increase in tube current reduces the exposure time and concomitant blur effect. The methods may be used alone or in combination; for example an x-ray tube with a larger, moveable static focal spot will result in a system that fully utilizes the x-ray tube generator, provides a high quality image with reduced blur and, due to the decrease in exposure time, may scan the patient more quickly.
    Type: Application
    Filed: May 30, 2013
    Publication date: October 3, 2013
    Inventors: Baorui Ren, Jay Stein, Zhenxue Jing, Andrew Smith
  • Publication number: 20130223591
    Abstract: A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view.
    Type: Application
    Filed: April 5, 2013
    Publication date: August 29, 2013
    Applicant: HOLOGIC, INC.
    Inventors: Zhenxue JING, Georgia HITZKE, Donald KENNEDY, Andrew SMITH, Jay A. STEIN
  • Patent number: 8515005
    Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.
    Type: Grant
    Filed: August 3, 2010
    Date of Patent: August 20, 2013
    Assignee: Hologic Inc.
    Inventors: Baorui Ren, Andrew Smith, Tom Farbizio, Zhenxue Jing, Jay Stein
  • Patent number: 8457282
    Abstract: An x-ray tube is described that includes components for increasing x-ray image clarity in the presence of a moving x-ray source by modifying focal spot characteristics, including focal spot size and focal spot position. In a first arrangement a static focal spot is moved in a direction contrary to the movement of the x-ray source so that an effective focal spot position is essentially fixed in space relative to one of the imaged object and/or detector during a tomosynthesis exposure. In a second arrangement, the size of the static focal spot is increased, and the resulting increase in tube current reduces the exposure time and concomitant blur effect. The methods may be used alone or in combination; for example an x-ray tube with a larger, moveable static focal spot will result in a system that fully utilizes the x-ray tube generator, provides a high quality image with reduced blur and, due to the decrease in exposure time, may scan the patient more quickly.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: June 4, 2013
    Assignee: Hologic, Inc.
    Inventors: Ren Baorui, Jay Stein, Zhenxue Jing, Andrew Smith
  • Patent number: 8416915
    Abstract: A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: April 9, 2013
    Assignee: Hologic, Inc.
    Inventors: Zhenxue Jing, Georgia Hitzke, Donald Kennedy, Andrew Smith, Jay A. Stein