Patents by Inventor Zhiqiang He

Zhiqiang He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240158475
    Abstract: Provided is an isolated binding protein including an antigen binding domain binding to an NS1 protein, and comprising specific heavy chain CDR and light chain CDR. The binding protein can specifically identify and bind to NS1, and has relatively high sensitivity and specificity, so as to detect dengue virus. Moreover, the binding protein does not need to be produced by injecting hybridoma cells into mouse peritoneal cavity, while simplifying production, thus stabilizing antibody functionality.
    Type: Application
    Filed: August 26, 2019
    Publication date: May 16, 2024
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG
  • Patent number: 11978583
    Abstract: A coil module includes a first planar coil winding that includes a plurality of turns of coils, at least one turn of first coil in the plurality of turns of coils includes at least one first cutting opening, and the first cutting opening divides the first coil into a first outer side part and a first inner side part along an extension direction of the coil, and a first target side part includes a first cutting groove, the first target side part is at least one of the first outer side part and the first inner side part, an extension direction of the first cutting groove is the same as an extension direction of the first target side part, and a width of a single first cutting groove is less than or equal to a width of a single first cutting opening.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: May 7, 2024
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Yongfa Zhu, Xiaowei Chen, Tao Ding, Zhiqiang Zeng, Chang Yang, Zhaodong He
  • Patent number: 11951560
    Abstract: The present disclosure provides a wire and arc additive manufacturing (WAAM) method for a titanium alloy. The method includes the following steps: step 1: performing a WAAM process assisted by cooling and rolling; step 2: milling side and top surfaces of an additive part; step 3: performing, by friction stir processing (FSP) equipment, an FSP process on the additive part, and applying cooling and rolling to a side wall of the additive part through a cooling and rolling device during the FSP process; step 4: finish-milling the top surface of the additive part for a WAAM process in the next step; and step 5: repeating the above steps cyclically until final forming of the part is finished. This WAAM method completely breaks dendritic structures and refines grains in the WAAM process of the titanium alloy, thereby effectively repairing defects such as pores and cracks.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: April 9, 2024
    Assignee: NORTHEASTERN UNIVERSITY
    Inventors: Changshu He, Jingxun Wei, Ying Li, Zhiqiang Zhang, Ni Tian, Gaowu Qin
  • Patent number: 11945042
    Abstract: The present disclosure provides a wire and arc additive manufacturing (WAAM) method for a magnesium alloy. The method includes the following steps: step 1: performing a WAAM process assisted by cooling and rolling; step 2: milling side and top surfaces of an additive part; step 3: performing, by friction stir processing (FSP) equipment, an FSP process on the additive part, and applying cooling and rolling to a side wall of the additive part through a cooling and rolling device during the FSP process; step 4: finish-milling the top surface of the additive part for a WAAM process in the next step; and step 5: repeating the above steps cyclically until final forming of the part is finished. The present disclosure completely breaks dendritic structures and refines grains in the WAAM process of the magnesium alloy, thereby effectively repairing defects such as pores and cracks.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: April 2, 2024
    Assignee: NORTHEASTERN UNIVERSITY
    Inventors: Changshu He, Jingxun Wei, Ying Li, Zhiqiang Zhang, Ni Tian, Gaowu Qin
  • Publication number: 20240097138
    Abstract: Provided are a composite material and a preparation method thereof, a negative electrode material, and a lithium ion battery. The negative electrode material includes at least one composite material, and the lithium ion battery includes at least one composite material. The composite material has a core-shell structure composed of an inner core and a hydrophobic coating layer, with the inner core including at least one lithium-containing silicon oxide, and the hydrophobic coating layer being used to cover the inner-core material.
    Type: Application
    Filed: September 22, 2021
    Publication date: March 21, 2024
    Applicants: BTR NEW MATERIAL GROUP CO., LTD., DINGYUAN NEW ENERGY TECHNOLOGY CO., LTD.
    Inventors: Zhiqiang DENG, Wei XIE, Chunlei PANG, Jianguo REN, Xueqin HE
  • Publication number: 20240093443
    Abstract: Disclosed in the present disclosure is a double-deck multi-span bridge construction method. According to the double-deck bridge construction method of the present disclosure, construction is carried out by using a method of disassembling a support jig frame in a graded and span-separated mode, an upper chord jig frame and a lower chord jig frame can be used in a recycle manner, and construction costs are reduced. In addition, a construction period of building the support jig frame is shortened, and other construction operations can be synchronously carried out on a span in which the jig frame is disassembled, for example, fire retardant coating construction can be carried out on a mounted bridge deck after the jig frame is disassembled, and the construction period of a double-deck multi-span bridge is effectively shortened.
    Type: Application
    Filed: September 23, 2021
    Publication date: March 21, 2024
    Applicant: CHINA CONSTRUCTION SCIENCE AND INDUSTRY CORPORATION LTD.
    Inventors: Jinglei REN, Bing SUN, Yonggang GAO, Hongyu SHEN, Shaohui ZHU, Jianguo QI, Cui LIU, Ruihua YAN, Zhiqiang HE, Longfei LI, Sijie YANG, Huaidong ZHANG, Xu CHEN, Wei JIANG, Wenbo LI, Yingwu SUN, Yuhang ZHANG
  • Patent number: 11905775
    Abstract: A driving system for a core drilling rig has a driving motor. The driving motor has an outer rotor and an inner stator, and mutually-matched convex ribs are provided on the inner wall of the outer rotor and the outer wall of the inner stator. The outer rotor and the inner stator are in clearance fit. A clearance between the outer rotor and the inner stator is a driving liquid channel. The length of the outer rotor is less than that of the inner stator. The outer rotor is provided between the front and rear ends of the inner stator. The outer rotor is connected to an outer cylinder. The rear end of the inner stator is connected to a coupling.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: February 20, 2024
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Mingzhong Gao, Heping Xie, Ling Chen, Jun Guo, Zhilong Zhang, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11859450
    Abstract: A drilling fluid channel structure of a core drilling rig includes a fluid channel activation module, a pressure relief module, a flow diverging and blocking module, a driving fluid channel and a cooling fluid channel. The fluid channel activation module, the pressure relief module and the flow diverging and blocking module are connected sequentially from the rear to the front. The driving fluid channel and the cooling fluid channel are connected at the rear side thereof to the flow diverging and blocking module. The driving fluid channel includes a driving section located between a stator and a rotor of a driving motor. The driving fluid channel is provided with a driving fluid outlet at the front side of the driving section. The cooling fluid channel passes through a layer disposed between an integrity-preserving compartment and an outer barrel.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: January 2, 2024
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Mingzhong Gao, Heping Xie, Ling Chen, Jun Guo, Zhilong Zhang, Zetian Zhang, Ru Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11846149
    Abstract: A core sampling and preservation system comprises the following sequentially connected modules: a drive module (300), a preservation module (200) and a core sampling module (100). The core sampling module (100) comprises a core drilling tool and a core sample storage compartment. The preservation module (200) comprises a core sample preservation container. The drive module comprises a core drill having a liquid channel. The core sample preservation container comprises an inner core barrel (28), an outer core barrel (26) and an energy storage device (229). The outer core barrel (26) is sleeved onto the inner core barrel (28). An upper end of the inner core barrel (28) is in communication with a liquid nitrogen storage tank (225). The liquid nitrogen storage tank (225) is positioned inside the outer core barrel (26). The energy storage device (229) is in communication with the outer core barrel (26). The outer core barrel (26) is provided with a butterfly valve (23).
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 19, 2023
    Assignee: SHENZHEN UNIVERSITY
    Inventors: Heping Xie, Mingzhong Gao, Ling Chen, Cunbao Li, Jianbo Zhu, Jun Guo, Zhiyi Liao, Cong Li, Zhiqiang He
  • Publication number: 20230400111
    Abstract: Disclosed is a magnetic pressure retaining control device, which comprises: a valve seat, a magnetic valve cover, and a trigger magnetic member for repelling the magnetic valve cover; the magnetic valve cover and an open end of the valve seat are movably connected; when the magnetic valve cover is in an open state, the trigger magnetic member is opposite to an end surface of the magnetic valve cover away from an inside of the valve seat. A cylindrical magnet is also arranged in the valve seat. By the magnetic between the trigger magnet and the magnetic valve cover, and the magnetic between the magnetic valve cover and the valve seat, a reliable guarantee for the closure between the magnetic valve cover and the valve seat is provided. The valve seat and the valve cover are tightly closed under different conditions.
    Type: Application
    Filed: July 15, 2021
    Publication date: December 14, 2023
    Inventors: Heping XIE, Mingzhong GAO, Guikang LIU, Ling CHEN, Bo YU, Cong LI, Chenghan FU, Jianjun HU, Mingqing YANG, Nianhan WU, Zhiqiang HE
  • Patent number: 11840890
    Abstract: A system for the in-situ retained coring of a rock sample has a driving module (300), a retaining module (200), and a coring module (100) which are connected in sequence. The coring module (100) includes a rock core drilling tool and a rock core sample storage cylinder, the retaining module (200) includes a rock core sample retaining compartment. The driving module includes a coring drill machine that has a drill machine outer cylinder unlocking mechanism. The rock core drilling tool includes a coring drill tool, a core catcher (11), and an inner core pipe (12). The coring drill tool has an outer core pipe (13) and a hollow drill bit (14). The rock core sample retaining compartment has an inner coring cylinder (28), an outer coring cylinder (26), and an energy accumulator (229).
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 12, 2023
    Assignee: SHENZHEN UNIVERSITY
    Inventors: Heping Xie, Mingzhong Gao, Ling Chen, Cunbao Li, Jianbo Zhu, Zhiyi Liao, Cong Li, Jun Guo, Zhiqiang He
  • Publication number: 20230391853
    Abstract: An antibody against a novel coronavirus, and a reagent and a kit for detecting the novel coronavirus, which relate to the technical field of antibodies. The antibody against the novel coronavirus includes a heavy chain complementarity determinant region and a light chain complementarity determinant region. The antibody has good affinity for N protein of the novel coronavirus, and has good sensitivity and specificity for detecting the novel coronavirus. Antibody options are provided for detection of the novel coronavirus.
    Type: Application
    Filed: September 10, 2021
    Publication date: December 7, 2023
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG, Wenjuan LOU, Lingyun FAN
  • Patent number: 11821271
    Abstract: Disclosed is a guiding and injecting integrated mechanism for continuous conduit, belonging to underground exploration technical field. The mechanism comprises a pair of chain wheel and chain clamping assemblies used for clamping conduit and pulling conduit to go down or out of well. A conduit guiding channel for conduit to pass through is formed between the pair of chain wheel and chain clamping assemblies, and an inlet and an outlet of the conduit guiding channel are not situated in line. The conduit guiding channel is arc-shaped and each of the two chain wheel and chain clamping assemblies comprises a chain wheel set, chains, clamping blocks mounted on the chain, and a pushing plate for pressing the clamping blocks. Further, clamping surfaces of the clamping blocks have a certain curvature with respect to guiding direction.
    Type: Grant
    Filed: December 3, 2020
    Date of Patent: November 21, 2023
    Assignee: SHENZHEN UNIVERSITY
    Inventors: Heping Xie, Mingzhong Gao, Ling Chen, Le Zhao, Mingqing Yang, Bo Yu, Jianan Li, Cong Li, Zhiqiang He, Yunqi Hu
  • Publication number: 20230349245
    Abstract: Disclosed is a continuous conduit apparatus based on guiding and injecting integrated mechanism, which comprises a straightening apparatus and a pair of sprocket and chain clamping assemblies. The pair of sprocket and chain clamping assemblies are configured to clamp the conduit and pull the conduit to go downwards a well or upwards a lifting direction. Between the pair of sprocket and chain clamping assemblies, a conduit guide channel applied for the conduit to passing through is formed. An inlet and an outlet of the conduit guide channel are not situated in a straight line, and the straightening apparatus are configured to straighten the conduit. Each of the two sprocket and chain clamping assemblies comprises a sprocket set, a chain, a plurality of clamping blocks mounted on the chain, and a pushing plate configured to press the clamping blocks.
    Type: Application
    Filed: December 3, 2020
    Publication date: November 2, 2023
    Inventors: Mingzhong GAO, Heping XIE, Mingqing YANG, Ling CHEN, Le ZHAO, Jianan LI, Bo YU, Cong LI, Zhiqiang HE, Yunqi HU
  • Publication number: 20230331784
    Abstract: The present disclosure relates to an HCV recombinant antigen and use of the same. Provided is an HCV recombinant antigen, which includes at least two NS3 antigens, at least one NS4 antigen, and at least one core antigen. Further provided are a nucleic acid encoding the HCV recombinant antigen, an expression vector containing the nucleic acid, a host cell containing the expression vector, a conjugate containing the HCV recombinant antigen, and a kit containing the HCV recombinant antigen, and the like.
    Type: Application
    Filed: April 16, 2021
    Publication date: October 19, 2023
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Zhongjie WEI, Jing CEN
  • Publication number: 20230331783
    Abstract: The application relates to an HCV recombinant antigen and a mutant thereof. The application provides an HCV recombinant antigen, the HCV recombinant antigen including at least 1 NS3 antigen, wherein at least one cysteine of the NS3 antigen in positions 1192-1517 of an HCV amino acid sequence is mutated into G and/or A, and preferably mutated into A. The application further provides a nucleic acid encoding the HCV recombinant antigen, an expression vector including the nucleic acid, a host cell including the expression vector, a conjugate including the HCV recombinant antigen, and a kit including the HCV recombinant antigen.
    Type: Application
    Filed: April 16, 2021
    Publication date: October 19, 2023
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Zhongjie WEI, Jing CEN
  • Patent number: 11788371
    Abstract: A coring device has core drilling tool, a core catcher, a rock core barrel, a drilling machine outer cylinder, a flap valve and an inner rod for pulling the rock core barrel. The core catcher is provided inside the lower end of the rock core barrel. The core drilling tool includes an outer core tube and a hollow drill bit. The upper end of the outer core tube is connected to the lower end of the drilling machine outer cylinder. The lower end of the outer core tube is connected to the drill bit. The lower end of the inner rod protrudes into the rock core barrel and is movable axially by a certain distance relative to the rock core barrel. The flap valve includes a valve seat and a sealing flap. The valve seat is coaxially mounted on the inner wall of the drilling machine outer cylinder.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 17, 2023
    Assignee: SHENZHEN UNIVERSITY SICHUAN UNIVERSITY
    Inventors: Heping Xie, Mingzhong Gao, Ling Chen, Zhiyi Liao, Zhilong Zhang, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11788370
    Abstract: A drilling control mechanism of a core drilling rig has a tooth drill and a core drilling rig. The core drilling rig is inside the tooth drill and engages with the drill in a sliding manner. A locking recess is formed at an inner wall of the tooth drill. A locking latch recess is formed at an outer wall of the core drilling rig and has a locking latch therein. The locking latch has a spring. When the locking recess is directly opposite the locking latch recess, the spring extends and the locking latch partially enters the locking recess. The core drilling rig has a central rod, a fluid channel activation module, an outer barrel, and outer barrel unlocking module and a flow diverging module. The central rod passes through the inner cavities of the fluid channel activation module, the outer barrel unlocking module and the flow diverging module.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 17, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Mingzhong Gao, Ling Chen, Heping Xie, Zhilong Zhang, Jun Guo, Zetian Zhang, Ru Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11781382
    Abstract: A drilling mechanism of a coring drilling rig has a central rod, a fluid channel starting module, an outer barrel, an outer barrel unlocking module, a flow diverging module and a drill bit. The central rod penetrates the fluid channel starting module. The outer barrel unlocking module and an inner cavity of the flow diverging module from back to front. The fluid channel starting module is behind the outer barrel and is connected to the outer barrel unlocking module. The flow diverging module is in front of the outer barrel unlocking module, and a hydraulic motor is connected in front of the flow diverging module. The outer barrel has a driving section that is a rotor of the hydraulic motor. The outer wall of the outer barrel is fixedly connected to a centralizer, and the front end of the outer barrel is connected to the drill bit.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 10, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Mingzhong Gao, Heping Xie, Ling Chen, Zhilong Zhang, Jun Guo, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11781390
    Abstract: A fidelity retaining type coring device for a rock sample, comprising a rock core drilling tool, a rock core sample storage barrel, and a rock core sample fidelity retaining cabin.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: October 10, 2023
    Assignee: SHENZHEN UNIVERSITY
    Inventors: Mingzhong Gao, Heping Xie, Ling Chen, Jianbo Zhu, Cunbao Li, Zhiyi Liao, Zhiqiang He, Jun Guo, Cong Li