Patents by Inventor Zhiqiang He

Zhiqiang He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220170335
    Abstract: A core sampling and preservation system comprises the following sequentially connected modules: a drive module (300), a preservation module (200) and a core sampling module (100). The core sampling module (100) comprises a core drilling tool and a core sample storage compartment. The preservation module (200) comprises a core sample preservation container. The drive module comprises a core drill having a liquid channel. The core sample preservation container comprises an inner core barrel (28), an outer core barrel (26) and an energy storage device (229). The outer core barrel (26) is sleeved onto the inner core barrel (28). An upper end of the inner core barrel (28) is in communication with a liquid nitrogen storage tank (225). The liquid nitrogen storage tank (225) is positioned inside the outer core barrel (26). The energy storage device (229) is in communication with the outer core barrel (26). The outer core barrel (26) is provided with a butterfly valve (23).
    Type: Application
    Filed: March 15, 2019
    Publication date: June 2, 2022
    Inventors: Heping XIE, Mingzhong GAO, Ling CHEN, Cunbao LI, Jianbo ZHU, Jun GUO, Zhiyi LIAO, Cong LI, Zhiqiang HE
  • Publication number: 20220162912
    Abstract: Disclosed is a system for the in-situ retained coring of a rock sample, the system comprising a driving module (300), a retaining module (200), and a coring module (100) which are connected in sequence, wherein the coring module (100) comprises a rock core drilling tool and a rock core sample storage cylinder, the retaining module (200) comprises a rock core sample retaining compartment; the driving module comprises a coring drill machine that comprises a drill machine outer cylinder unlocking mechanism; the rock core drilling tool comprises a coring drill tool, a core catcher (11), and an inner core pipe (12); the coring drill tool comprises an outer core pipe (13) and a hollow drill bit (14); and the rock core sample retaining compartment comprises an inner coring cylinder (28), an outer coring cylinder (26), and an energy accumulator (229). The system is conducive to retaining the state of a rock core in an in-situ environment, and can improve the drilling rate and improve the coring efficiency.
    Type: Application
    Filed: March 15, 2019
    Publication date: May 26, 2022
    Inventors: Heping XIE, Mingzhong GAO, Ling CHEN, Cunbao LI, Jianbo ZHU, Zhiyi LIAO, Cong LI, Jun GUO, Zhiqiang HE
  • Publication number: 20220033484
    Abstract: Disclosed is an isolated binding protein including a cardiac troponin I (cTnI) antigen binding domain, and preparation and a use and the like of the binding protein. The antigen binding domain includes at least one complementarity determining region selected from an amino acid sequence defined in this article, or has at least 80% sequence identity with the complementarity determining region of the amino acid sequence and has KD?9.96×10?8 mon affinity with cTnI. The binding protein may be used in the detection field of the cTnI protein.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 3, 2022
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG
  • Publication number: 20220033483
    Abstract: Disclosed is an isolated binding protein including a cardiac troponin I (cTnI) antigen binding domain, and preparation and a use and the like of the binding protein. The antigen binding domain includes at least one complementarity determining region selected from an amino acid sequence defined in this article, or has at least 80% sequence identity with the complementarity determining region of the amino acid sequence and has KD?7.51×10?8 mol/L affinity with cTnI. The binding protein may be used in the detection field of the cTnI.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 3, 2022
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG
  • Publication number: 20220002395
    Abstract: Provided is an anti-Plasmodium falciparum HRP-II antibody or an antigen-binding fragment thereof. The antibody comprises a heavy chain CDR1-3 shown in SEQ ID NO: 1-3 and a light chain CDR1-3 shown in SEQ ID NO: 4-6. Also provided are an application of the antibody and a method for preparing the antibody.
    Type: Application
    Filed: October 15, 2019
    Publication date: January 6, 2022
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG, Lina TANG, Bi LIANG, Hui YOU
  • Publication number: 20210403601
    Abstract: Provided is an isolated binding protein including a Taq DNA polymerase antigen-binding domain. The antigen-binding domain includes at least one complementarity determining region selected from CDR-VH1-3 and CDR-VL1-3, or has at least 80% sequence identity with the complementarity determining region and has an affinity of KD?8.568×10?9 mol/L to the Taq DNA polymerase. The binding protein may be used in the field of molecular detection.
    Type: Application
    Filed: October 1, 2019
    Publication date: December 30, 2021
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG, Hao YANG, Bi LIANG, Hui YOU, Qiuyan MA, Weizhi LI
  • Publication number: 20210407656
    Abstract: Method and system for grading a medical image. For example, a system for grading a medical image comprising a grading network configured to provide a grading result corresponding to the medical image based on at least the medical image and/or a list of lesion candidates generated by a lesion identification network.
    Type: Application
    Filed: September 8, 2021
    Publication date: December 30, 2021
    Inventors: JIE-ZHI CHENG, Zaiwen Gong, Zhiqiang He, Yiqiang Zhan, Xiang Sean Zhou
  • Publication number: 20210395394
    Abstract: Provided are an isolated binding protein including a pan-species-specific plasmodium lactate dehydrogenase antigen binding domain and a preparation method thereof. The antigen binding domain includes at least one complementarity determining region selected from a defined amino acid sequence, or has at least 80% of sequence identity with the complementarity determining region of the following amino acid sequence and an affinity of KD?1.5647×10?9 mol/L with a pan-species-specific plasmodium lactate dehydrogenase, and may identify the pan-species-specific plasmodium lactate dehydrogenase. The binding protein may be applied to the field of detection of plasmodium lactate dehydrogenase proteins.
    Type: Application
    Filed: October 1, 2019
    Publication date: December 23, 2021
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG, Lina TANG, Bi LIANG, Hui YOU
  • Publication number: 20210395347
    Abstract: Provided is an isolated binding protein including an antigen binding domain binding to an NS1 protein, and including specific heavy chain CDR and light chain CDR. The binding protein can specifically identify and bind to NS1, and has relatively high sensitivity and specificity, so as to detect dengue vims. Moreover, the binding protein does not need to be produced by injecting hybridoma cells into mouse peritoneal cavity, while simplifying production, thus stabilizing antibody functionality.
    Type: Application
    Filed: August 26, 2019
    Publication date: December 23, 2021
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG
  • Publication number: 20210341306
    Abstract: A navigation system for a motor vehicle is provided. A display interface is located in a vehicle. A is processor in communication with a vehicle sensor and a server. The processor is configured to receive vehicle information and road information, predict a traveling direction of the vehicle based on the vehicle information, and highlight the road information associated with the traveling direction on the display interface. A corresponding vehicle and method is also provided. A user of a navigation map can obtain auxiliary information to drive on the current route from a navigation interface more conveniently during the process of using the navigation map, thus providing the user an improved driving experience.
    Type: Application
    Filed: April 30, 2021
    Publication date: November 4, 2021
    Applicant: FORD GLOBAL TECHNOLOGIES, LLC
    Inventors: Zhiqiang HE, Yuan Yan ZHANG, Qinchao ZHOU
  • Publication number: 20210340231
    Abstract: The present invention provides an isolated binding protein comprising a cTnI antigen binding domain. The antigen binding domain comprises at least one complementarity determining region selected from amino acid sequences defined herein, or has sequence identity of at least 80% to the complementarity determining region of said amino acid sequence and an affinity of KD?1.41×10?9 mol/L to cTnI. The binding protein can be used for detection of cTnI protein.
    Type: Application
    Filed: September 27, 2019
    Publication date: November 4, 2021
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG, Hui YOU, Lingyun FAN
  • Publication number: 20210324054
    Abstract: Provided is an isolated binding protein including an antigen-binding domain that binds to NS1 protein. The isolated binding protein includes specific heavy chain CDRs and light chain CDRs. The binding protein can specifically recognize and bind to NS1, and has relatively high sensitivity and specificity, thereby achieving the detection of dengue virus. Moreover, the binding protein is not required to be produced by inducing hybridoma cells in mouse abdominal cavity, and thus it is simple in production and has more stable antibody function.
    Type: Application
    Filed: August 26, 2019
    Publication date: October 21, 2021
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG
  • Patent number: 11145405
    Abstract: Method and system for grading a medical image. For example, a system for grading a medical image comprising a grading network configured to provide a grading result corresponding to the medical image based on at least the medical image and/or a list of lesion candidates generated by a lesion identification network.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: October 12, 2021
    Assignee: Shanghai United Imaging Intelligence Co., Ltd.
    Inventors: Jie-Zhi Cheng, Zaiwen Gong, Zhiqiang He, Yiqiang Zhan, Xiang Sean Zhou
  • Publication number: 20210301000
    Abstract: Provided is an isolated binding protein including an antigen binding domain binding to an NS1 protein. The binding protein can identify and bind to the NS1 protein so as to detect dengue virus.
    Type: Application
    Filed: August 26, 2019
    Publication date: September 30, 2021
    Inventors: Peng CUI, Zhiqiang HE, Yuan MENG, Dongmei ZHONG
  • Patent number: 11043068
    Abstract: An interactive application processing method is described. A selection of an online interactive activity by a user is received in an interactive application. The online interactive activity is associated with an offline interactive activity. According to a past performance result, a determination is made, by circuitry of an interactive application apparatus, as to whether the user qualifies to participate in the offline interactive activity. When the user is determined to qualify to participate in the offline interactive activity, identity information of the user is acquired. A certificate is generated based on the identity information for allowing the user to participate in the offline interactive activity.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: June 22, 2021
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Yong Fan, Zhiqiang He, Jing Zhou, Wuming Yin, Caiming Fu, Xuan Yu, Mingang Huang, Yi Liu, Xiaohui Chen, Xiaohui Zheng, Ran Ding, Xiejuan Liao, Kan Liao, Yancen Lin, Xiongfei Wu, Ming Han, Yuan Yuan, Xin Zhang, Qingxin Chen, Sheng Huang, Yihua Jin, Yu Chen
  • Publication number: 20210172951
    Abstract: The present disclosure relates to the field of medical diagnosis, and specifically, relates to a synthetic peptide for detecting HIV-1. The synthetic peptide is obtained by mutating the amino acid sequence set forth as SEQ ID NO: 1. The synthetic peptide can better detect anti-HIV-1 antibodies, and can better avoid potential “false negative” and “false positive” results.
    Type: Application
    Filed: August 6, 2019
    Publication date: June 10, 2021
    Applicant: Fapon Biotech Inc.
    Inventors: Peng Cui, Zhiqiang He, Yuan Meng
  • Patent number: 10893125
    Abstract: The present invention discloses a method and a server for allocating game resources, which belongs to the field of network technology. The method includes: receiving a game participation request including game subzone information sent by a user; when the user enters a game subzone identified by the game subzone information, assigning the user to a waiting queue corresponding to the user in the game subzone in accordance with a predetermined condition; and when the user is successfully assigned to the waiting queue, selecting participants to play in the same group with the user from waiting queues other than the waiting queue of the user, and allocating game resources for the user and the selected participants. The present technical solution can effectively reduce occurrence of the game participants' cheating.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: January 12, 2021
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Liang Ma, Jing Zhou, Zhiqiang He, Xuan Yu, Qi Li, Tao Lin
  • Publication number: 20200211695
    Abstract: Method and system for grading a medical image. For example, a system for grading a medical image comprising a grading network configured to provide a grading result corresponding to the medical image based on at least the medical image and/or a list of lesion candidates generated by a lesion identification network.
    Type: Application
    Filed: July 12, 2019
    Publication date: July 2, 2020
    Inventors: JIEZHI ZHENG, ZAIWEN GONG, ZHIQIANG HE, YIQIANG ZHAN, XIANG SEAN ZHOU
  • Publication number: 20200182000
    Abstract: The present disclosure relates to the field of scientific drilling technology and provides a deep rock quality assurance coring device and coring method thereof. The deep rock quality assurance coring device comprises a drilling tool, a drilling bit, a central rod and a core storage body, wherein the drilling bit is mounted at the lower end of the drilling tool, the lower end of the central rod is connected to the core storage body, and the central rod is capable of driving the core storage body to move in the drilling tool in an axial direction of the drilling tool, a reservoir chamber having a lower end opening is arranged in the central rod, a core storage chamber having a lower end opening is arranged in the core storage body.
    Type: Application
    Filed: December 9, 2019
    Publication date: June 11, 2020
    Inventors: Heping Xie, Tao Liu, Ling Chen, Mingzhong Gao, Ru Zhang, Yifan Wu, Zhiqiang He
  • Patent number: D949674
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: April 26, 2022
    Inventors: Zhifeng He, Zhiqiang He