Abstract: Disclosed in the present invention are a series of fused polycyclic substituted 5-carboxylic acid thienopyrimidine dione compounds and the use thereof. Specifically disclosed are a compound represented by formula (H) and a pharmaceutically acceptable salt thereof.

Abstract: A monitoring system based on a digital converter station includes a first monitoring terminal deployed at a first-level monitoring side, a second monitoring terminal deployed at a second-level monitoring side, and a third monitoring terminal deployed at a third-level monitoring side; the monitoring terminal at each level includes a communication module, a human-machine interaction module, a device status monitoring module, a device alarm management module, a video fusion processing module, and a data transmission adjustment and control module.

Abstract: Embodiments provided herein, provide for variant IgG Fc polypeptides, dimeric molecules, pharmaceutical compositions, and methods that can be used to target at cells to modulate the activity of the same to treat disorders, such as autoimmune disorders or cancers.

Abstract: The present disclosure relates to a video retrieval method, a method, system and device for generating a video retrieval mapping relationship, and a storage medium. The video retrieval method comprises: acquiring a retrieval instruction, wherein the retrieval instruction carries retrieval information for retrieving a target frame picture; and obtaining the target frame picture according to the retrieval information and a preset mapping relationship.

Abstract: Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.

Abstract: A transient electromagnetic device with variable shape and turns includes squares, a transmitting coil carrying frame, a transmitting coil, a turns-variable device, a current generator and a working power supply. The transmitting coil carrying frame is arranged inside the transmitting coil; the transmitting coil carrying frame is configured as a carrier of the transmitting coil, and configured for adjusting a side length of the transmitting coil and a shape of the transmitting coil; the square is configured for clamping and connecting the transmitting coil and the transmitting coil carrying frame to fix the transmitting coil to the transmitting coil carrying frame. The current generator is configured for generating transient current; the turns-variable device is configured for changing the turns of the transmitting coil; and the transmitting coil is configured for transmitting the transient current to a target area to be measured.

Abstract: The present application relates to components, such as dental apparatuses, having geometrical features to facilitate post-fabrication cleaning, including methods of fabricating the same. In one embodiment, a dental apparatus, such as a retainer, an aligner, or a dental attachment placement appliance, comprises one or more concave surfaces for which one or more apertures is formed therethrough at or near a maximum depth of a given concave surface.

Abstract: A fan-out semiconductor device includes stacked semiconductor dies having die bond pads arranged in columns exposed at a sidewall of the stacked semiconductor dies. The stacked dies are encapsulated in a photo imageable dielectric (PID) material, which is developed to form through-hole cavities that expose the columns of bond pads of each die at the sidewall. The through-hole cavities are plated or filled with an electrical conductor to form conductive through-holes coupling die bond pads within the columns to each other.

Abstract: A method for forming a complex shape three-dimensional ceramic article by printing a first layer of a first material having a first fraction of first ceramic particles and a first fraction of a first polymeric ceramic precursor. A second layer is printed such that it is at least partially disposed on the first layer of a second material having a second fraction of second ceramic particles and a second fraction of a second polymeric ceramic precursor. A composite of the first layer and the second layer is heated at a temperature sufficient to decompose the first and second polymeric ceramic precursors and sinter the article. During the sintering process, the first and second layers with different fractions of ceramic particles undergo different degrees of shrinkage, resulting in a tuneable mismatch of the bilayer structure and accurately achieving a targeted geometry.

Abstract: In embodiments of the present disclosure, there is provided an approach for fact checking based on semantic graphs. According to embodiments of the present disclosure, after obtaining a text to be fact checked, a plurality of evidence sentences related to the text are retrieved from an evidence database. Then, semantic graphs of the text and the evidence sentences are constructed based on the semantic analysis, and a veracity of a statement in the text can be determined based on the semantic graphs. Embodiments of the present disclosure propose a graph-based reasoning approach for fact checking, and use the constructed semantic graphs to facilitate verification of the truthfulness of the text, thereby improving the accuracy for fact checking.

Abstract: A method for controlling a device for automatically adjusting an airway opening body position is provided. The device includes a horizontal base plate, a head support block, a back support plate, a neck support apparatus, a head cover assembly, and a programmable logic controller (PLC). The neck support apparatus is positioned between the head support block and the back support plate. The PLC is configured to controls a stroke of an electric cylinder according to the following equations: ?=1.235?+?, and ?=KX+B+C, where ? is a body position angle, the body position angle is an angle between a positive projection line of a connecting line from a mandibular angle to an external acoustic meatus on a symmetrical surface of a human body and the back support plate, and ? is a preset value ranging from 90° to 100°.

Abstract: Provided herein are methods for regenerating hair cells in an adult mammalian inner ear using novel combinations of agents selected from the group consisting of a histone deacetylase (HDAC) inhibitor, one or more inhibitory nucleic acids targeting Fir, Mxi1, Fbxw7, or a combination thereof, a Wnt pathway activator, and a cAMP activator. The methods and compositions can be used to treat a subject with hearing loss or vestibular dysfunction.

Abstract: A sterilization and deodorization waste container having dual-wave band ultraviolet lamp tube includes an isolation chamber provided on an inner side of a container lid and a dual-wave band ultraviolet lamp tube installed in the isolation chamber. The dual-wave band ultraviolet lamp tube is capable of simultaneously generating a direct ultraviolet light wave and an ozone ultraviolet light wave. The isolation chamber includes a reflector housing having a light transmitting window facing an inner cavity of a container body. The dual-wave band ultraviolet lamp tube is controlled by a control circuit to turn on to generate the ultraviolets into an inner cavity of the container body while the container lid is closed and to turn off to stop generating the ultraviolet while the container lid is opened.

Abstract: A follow-hold switch circuit comprising: a follower; a sampling sub-circuit for voltage sampling; a bootstrap-control sub-circuit, which provides a bootstrap voltage to the sampling sub-circuit when the circuit is in a following state; a sampling-switch-control sub-circuit, which provides a common-mode voltage to a bootstrap capacitor in the bootstrap-control sub-circuit when the circuit is in a holding state; the follower is connected to an output of the sampling sub-circuit; the sampling sub-circuit is connected to the bootstrap-control sub-circuit and the sampling-switch-control sub-circuit respectively through a sampling switch; the present disclosure can effectively improve the linearity of sampling switches.

Abstract: A device may include a display for displaying an image frame based on warped image data and image processing circuitry to generate the warped image data by warping input image data to account for one or more distortions associated with displaying the image. The image processing circuitry may include a two-stage cache architecture having an first cache and an second cache and warp the input image data by generating mapping data indicative of a warp between the input image space and the output image space and fetching the input image data to populate the first cache. Warping may also include populating the second cache with a grouping of pixel values from the first cache that are selected according to a sliding window that traverses the first cache based on the mapping data and interpolating between pixel values of the grouping to generate pixel values of the warped image data.

Abstract: A digital-display control apparatus of a garbage can with adjustable sensing distance includes an emitter, a receiver, amplifier, an analog to digital converter, an analog to digital conversion result register connected to the receiver via the amplifier and the analog to digital convertor, a comparison unit, a sensing distance adjustable register, a microcomputer control unit, a drive circuit, and a digital displayer and keys, which is capable of selecting the sensing distance by directly pressing keys or choose the predetermined sensing distance.

Abstract: A blockchain based numerical value ranking method includes: using, by a first participant, a public key of the first participant to encrypt a private value of the first participant to obtain an encrypted text of the first participant; obtaining encrypted texts of other participants, and generating a challenge value having a preset bit length; based on the challenge value and the private value of the first participant, and the encrypted texts and public keys of the other participants, determining mixed results of the first participant with respect to the other participants; and determining a numerical value ranking result between the first participant and a second participant based on the mixed result of the second participant with respect to the first participant.

Abstract: A blockchain based numerical value ranking method includes: using, by a first participant, a public key of the first participant to encrypt a private value of the first participant to obtain an encrypted text of the first participant; obtaining encrypted texts of other participants, and generating a challenge value having a preset bit length; based on the challenge value and the private value of the first participant, and the encrypted texts and public keys of the other participants, determining mixed results of the first participant with respect to the other participants; and determining a numerical value ranking result between the first participant and a second participant based on the mixed result of the second participant with respect to the first participant.

Abstract: Disclosed are a soft bistable magnetic actuator, a fabrication method thereof, a fatigue testing device, and an auto underwater vehicle. The method for fabricating the soft bistable magnetic actuator includes the following operations: casting a soft precursor by injection molding, wherein the soft precursor consists of a soft deformable portion and a soft peripheral portion surrounded, the soft deformable portion is made of magnetic particles and polymer, and the soft peripheral portion is made of a magnetic particle, a mixture of organic liquid, and polymer; and extracting the organic liquid by an organic solvent shrinks the soft peripheral portion, buckles the soft deformable portion towards one side.