Abstract: In certain embodiments, an ophthalmic laser system for treating a floater in a vitreous of an eye includes a laser device that directs laser pulses towards the floater to yield cavitation bubbles that create a bubble jet to treat the floater. In some examples, the laser device includes a beam multiplexer that splits a laser beam into multiple beams that form the cavitation bubbles that create the bubble jet. In some examples, the laser device directs laser pulses towards the floater according to a pulse pattern that forms the cavitation bubbles that create the bubble jet.

Abstract: In certain embodiments, an ophthalmic laser surgical system for imaging and treating a target in an eye includes an imaging system with an optical coherence tomography (OCT) device that directs an OCT imaging beam along an imaging beam path towards the target in the eye, and generates OCT images from the OCT imaging beam reflected from the eye. The beam combining and alignment device aligns the OCT imaging beam and the laser beam. The laser-OCT xy-scanner: receives the OCT imaging beam from the imaging system, directs the OCT imaging beam along the imaging beam path towards the eye, and scans the OCT imaging beam in an xy-plane in the eye; and receives the laser beam from the laser device, directs the laser beam along the laser beam path aligned with the imaging beam path towards the eye, and scans the laser beam in the xy-plane in the eye.

Abstract: In certain embodiments, an ophthalmic laser system includes a laser device and a computer, where the laser device includes a laser and a phase modulator. The laser device directs a laser beam towards a target in an eye, where an intraocular lens (IOL) is disposed within the eye. The IOL has a phase profile that yields an IOL phase shift of light entering the eye. The laser generates the laser beam. The phase modulator has a phase front that yields a first phase shift of the laser beam that changes to a second phase shift when the laser beam reaches the IOL. The second phase shift is an inverse to the IOL phase shift.

Abstract: In certain embodiments, a surgical contact lens system for ophthalmic treatment with a laser beam includes a patient contact lens and a surgical contact lens. The patient contact lens reduces one or more refractive errors of the eye and has a concave surface and a convex surface. The concave surface is to be disposed outwardly from a cornea of an eye. The surgical contact lens has an eye end to be disposed outwardly from the convex surface of the patient contact lens. The surgical contact lens includes a frame and an optical component coupled to the frame. The patient contact lens reduces pressure from the surgical contact lens to reduce corneal folding of a posterior surface of the cornea. The optical component of the surgical contact lens and the patient contact lens transmit the laser beam to treat the eye.

Abstract: In certain embodiments, an ophthalmic laser system includes a laser device, an ophthalmic microscope, a z-direction sensor, and a controller. The laser device directs a laser beam towards a target within an eye. The ophthalmic microscope receives light from a focal point within the eye to provide an image of an object at the focal point. The z-direction sensor determines the z-position corresponding to the focal point of the ophthalmic microscope. The controller determines a position Z0, the z-position where the focal point of the ophthalmic microscope is at the retina of the eye; determines a position Z, the z-position where the focal point of the ophthalmic microscope is at the target within the eye; calculates a target-to-retina distance ?Z according to a difference between the position Z and the position Z0; and calculates a radiant exposure He at the retina according to the target-to-retina distance ?Z.

Abstract: Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.

Abstract: An apparatus to treat a patient comprises a laser beam, a measurement module, a scanner and a curved patient interface lens. The curved patient interface is measured with a pattern so as to determine a plurality of distances of the curved surface at a plurality of measurement locations. The measurement pattern may comprise the plurality of measurement locations distributed about a central measurement axis corresponding to the laser treatment axis. The plurality of measurement locations of the curved surface may correspond to a portion of a planned treatment profile, such that the measured distances correspond to alignment of the planned treatment. The plurality of distances can be used to determine an apex of the curved surface of the patient interface and to align the laser treatment axis with the apex of the curved surface.

Abstract: Systems and methods are disclosed for selectively allowing or preventing output of laser pulses. In some embodiments, a laser system comprises a shutter and a shutter motor. The shutter motor is configured to move the shutter in an alternating manner between a first position in which output of laser electromagnetic radiation is allowed a second position in which output of laser electromagnetic radiation is prevented.

Abstract: Systems and methods are disclosed for a surgical laser system with illumination. In some embodiments, a laser system comprises a surgical laser and an illumination source having their outputs combined into a fiber-optic cable and directed by the fiber-optic cable to a target surface. The illuminating visible light may be continuous and/or in pulses. Surgical laser pulses and illumination pulses may be synchronized for a stroboscopic effect. The laser system may also monitor laser electromagnetic radiation that is returned back through the fiber-optic cable.

Abstract: In certain embodiments, an ophthalmic surgical system for ablating tissue of an eye comprises controllable components (such as a light source and a scanner), optical elements, and a computer. The light source generates a light beam comprising pulses, where a propagation direction of the light beam defines a z-axis. The scanner directs a focal point of the light beam in an xy-plane orthogonal to the z-axis. The optical elements shape and focus the focal point of the light beam at a treatment region of the eye. The computer instructs one or more of the controllable components to generate the light beam comprising the pulses, where each pulse has a fluence greater than 1 J/cm2. An optical element of the optical elements focuses the focal point of the light beam with a spot size of less than 0.4 mm at the treatment region according to a focal spot pattern.

Abstract: According to certain embodiments, an ophthalmic surgical system for treating presbyopia comprises controllable components and a computer. The controllable components comprise a light source that generates a light beam and a scanner that directs a focal point of the light beam. The computer determines an ablation profile to remove tissue from a central region and a peripheral region of a cornea of a first eye of a pair of eyes. The ablation profile is designed to remove tissue from the central region to yield a protrusion to provide for near-vision, and to remove tissue from the peripheral region to correct to emmetropia.

Abstract: An ophthalmic system for visualization of interactions between ocular matter and a probe tip of a probe within or in contact with an ocular space of an eye includes: a visualization tool having a field of view that includes at least a portion of the ocular space of the eye where the probe tip interfaces with the ocular matter; and a stroboscopic illumination source configured to stroboscopically illuminate at least the portion of the field of view at an illumination frequency. A method of operating a stroboscopic illumination source during an ophthalmic surgical procedure includes: identifying an illumination source type of the stroboscopic illumination source; identifying a probe type; identifying a first procedure trigger; and operating the stroboscopic illumination source based on the probe type, the illumination source type, and the first procedure trigger.

Abstract: In certain embodiments, an ophthalmic surgical system for creating a lenticule in the cornea of an eye comprises controllable components (including a laser source and a scanner) and a computer. The laser source generates a laser beam, and the scanner directs the focal point of the laser beam. The computer determines a lenticule design for the lenticule having a posterior side and an anterior side. Either the posterior side or the anterior side has a central portion and a peripheral portion. The lenticule design is formed using a major lenslet and a minor lenslet, where the major lenslet is designed to correct to emmetropia. The lenticule design is formed by subtracting the minor lenslet from the major lenslet, where the subtraction of the minor lenslet yields the central portion. The computer instructs one or more of the controllable components to create the lenticule.

Abstract: The disclosure provides an ophthalmic surgical microscope including an optical axis. The ophthalmic surgical microscope also includes at least one light source configured to provide illumination having a wavelength range between 575 nm and 625 nm. The ophthalmic surgical microscope further includes a control device for directing the illumination at an acute angle relative to the optical axis of the microscope.

Abstract: A laser surgical system comprises a laser source, scanners, delivery optics, and a computer. The laser source generates a beam of femtosecond laser pulses. The scanners direct focus spots of the beam towards points of a cornea. The delivery optics focuses the focus spots at the points of the cornea. The computer creates an incision in the cornea by instructing the optics and scanners to: direct and focus the focus spots from a posterior corneal surface, through a convex curve and a concave curve, to an anterior corneal surface to form an S-curve incision with a posterior end and an anterior end. The S-curve incision has a substantially non-planar rectangular shape with a longer side that extends from the posterior end to the anterior end and defines a longer direction. A cross-section of the incision in the longer direction exhibits the convex curve and the concave curve.

Abstract: In certain embodiments, an ophthalmic laser system comprises a laser source, multi-focal optics, scanners, delivery optics, and a computer. The laser source generates a laser beam of ultrashort laser pulses. The multi-focal optics multiplex the laser beam to yield focus spots in a target along a propagation axis of the laser beam. The scanners direct the laser beam in x, y, and z directions. The delivery optics focus the laser beam within the target to form the focus spots in the target along the propagation axis of the laser beam. The computer instructs the scanners and the delivery optics to direct and to focus the focus spots at the target according to a scan pattern.

Abstract: The devices and methods described herein provide improved methods for accurately identifying and locating the visual axis of the eye and its intersection with the iris plane. In one embodiment, a visual axis identification system includes a fixation light source, a camera, and a processing system. During operation thereof, the patient focuses their gaze onto two or more fixation light spots provided by the fixation light source upon an optical axis thereof, which creates two or more corresponding images on or near to the patient's retina. The patient's head is then rotated relative while the patient continuously maintains their gaze on the fixation light spots. The patient's visual axis may be located by determining the location of the optical axis of the fixation light source relative to the patient's eye when the centers of the multiple images coincide in the patient's view.

Abstract: The disclosure provides a method for correcting higher-order aberrations including providing a laser radiation. The method also includes controlling a location of a beam focal point of the laser radiation by a system of scanners and guiding the beam focal point in such a way that the location of the beam focal point is in a cornea of an eye. The method further includes introducing the laser radiation into the cornea of the eye. The method includes cutting a lenslet, wherein a thickness of the lenslet t(X/Y) satisfies a following equation: t(X/Y)=t0+?t(X,Y)/(n?1), where ?t(X,Y) represents a higher-order wavefront elevation and to represents the thickness of the lenslet having a spherical refractive power of D.

Abstract: The present disclosure generally relates to methods and apparatus for accurate identification of the visual axis of the eye. In one embodiment, a visual axis identification system includes a fixation light source, a camera, a processing system, and a multifocal lens. The patient focuses their gaze through the multifocal lens and onto a fixation light beam provided by the fixation light source. The passage of the fixation light beam through the multifocal lens creates two or more images on or near to the patient's retina. The multifocal lens and/or the patient's eye are then moved relative to each other while the patient continuously maintains their gaze on the fixation light beam. The patient's visual axis may be located by determining the location of the optical center of the multifocal trial lens relative to the patient's eye when the centers of the multiple images coincide on the retina.

Abstract: Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.