Accommodating intraocular lens
An accommodating intraocular lens is disclosed that provides vision accommodation in response to contraction of an eye's ciliary muscle. The intraocular lens includes a deformable elastic dynamic lens having a non-accommodating surface curvature and a lens-shaping member having flexible portions in contact with peripheral edge regions of the dynamic lens for enabling compressive deformation thereof for changing the lens surface curvature to achieve accommodation. The intraocular lens also includes an elastically flexible coil member mounted around the lens-shaping member flexible portions. A first lens-supporting member has a proximal end region that engages the flexible coil member and a second lens-supporting member has a proximal end region connected to the lens-shaping member.
1. Field of the Invention
The present invention relates generally to the field of ophthalmics, more particularly to ophthalmic devices, still more particularly to ophthalmic devices known as intraocular lenses (IOLs), and especially to accommodating intraocular lenses.
2. Background Discussion
At the onset it may helpful to the understanding of the present invention to define the terms “phakic” and “aphakic” as related to human eyes. The term “phakic” is applied to an eye in which the natural ocular lens is still present. This is in contrast to an “aphakic” eye from which the natural ocular lens has—for any reason—been removed. A phakic eye is considered a dynamic or active eye because the living natural lens is subject to change over time, while an aphakic eye is considered a static eye because the natural lens has been removed.
Vision in a normal, healthy eye is enabled by light from a viewed object being refracted to the retina in turn by the cornea and the natural lens located rearwardly of the cornea. An important function of the natural lens, through a process of ciliary muscle contraction and zonular relaxation, is the providing of accommodation, that is, the ability of the elastic natural lens to change its curved shape to enable the eye to focus on objects at distances from near to far in response to the eye and brain sensing an out-of-focus image.
A relatively common ocular problem is impaired or complete loss of vision due to the natural ocular lens becoming cloudy or opaque—a condition known as cataract. The formation of cataracts is typically age related, most individuals over the age of about 60 years suffering from cataracts at least to some extent.
Cataracts cannot currently be cured, reversed, or even significantly arrested. Accordingly, treatment of cataracts involves surgically removing the natural lens when the lens becomes so cloudy that vision is greatly impaired, the result being that a phakic eye becomes an aphakic eye. After a defective natural lens has been surgically removed, the current vision-restoring practice (since about the 1940's) is to implant in the aphakic eye an artificial refractive lens called an intraocular lens (IOL). Previously, thick, heavy, high diopter spectacles were prescribed for aphakic eyes. However, most patients dislike such spectacles because of their uncomfortable weight and unattractive appearance.
Although the implanting of an IOL can generally restore vision in an aphakic eye, corrective spectacles or contact lenses are still usually required for near or far vision, depending upon whether the implanted IOL is selected for far or near vision. This is because, to the knowledge of the present inventor, IOLs providing accommodation comparable to that of a natural healthy lens have not heretofore been available; although, the development of accommodating IOLs has been widely sought.
In addition to the desirability of implanting accommodating IOLs in aphakic eyes in place of the removed natural lens, the implanting of accommodating IOLs would be advantageous in phakic eyes in which the intact natural lens, while still otherwise clear, has lost all or much of its accommodating properties, for example, by becoming less flexible. Nevertheless, the ciliary muscle, which normally functions to provide accommodation of the natural lens generally, remains active for most of an individual's life.
Efforts toward developing accommodating IOLs have relied upon axial IOL movement in the eye and/or IOL lens surface shape change to create dynamic change in ocular power and thus provide accommodation.
Axial movement of implanted IOLs in the eye to provide accommodation is disclosed, for example, in U.S. Pat. Nos. 5,476,514; 5,496,366; 5,674,282 and 6,197,059 to Stuart Cumming. Difficulties associated with axial IOL movement to provide accommodation are due both to the extremely limited ocular space for axial IOL movement that limits the achievable diopter variation necessary for full accommodation, and to satisfactory ocular mechanisms for causing such axial IOL movement.
On the other hand, lens surface shape changing, exemplified in the disclosures of U.S. Pat. Nos. 4,842,601; 4,888,012; 4,932,966; 4,994,082; 5,489,302 have required a spherical lens shape to interact with the rim of ciliary muscle in more then one meridian or even from all 360° orientations. This requires perfect lens centration in regard to the ciliary rim and equal interaction from all meridians; otherwise, absence of central symmetry leads to unequal lens surface curvature in different meridians with resulting reduction in image quality.
Because of these and other problems, a principal objective of the present invention is to provide an improved, surface shape changing accommodating IOL that relies on the interaction with the ciliary muscle in only one meridian. Such improved surface shape changing IOLs may be configured for implanting in aphakic eyes or may alternatively configured for implanting in phakic eyes.
SUMMARY OF THE INVENTIONIn accordance with the present invention, there is provided an accommodating intraocular lens for implanting in an individual's eye. The accommodating intraocular lens comprises a deformable elastic dynamic lens, which is preferably formed from a silicone or acrylic material, having a non-accommodating surface curvature and a lens-shaping member having flexible portions in contact with peripheral edge regions of the dynamic lens for enabling deformation of the lens for changing the lens surface curvature.
Included in the accommodating intraocular lens are an elastically flexible member, which may be constructed from a shape memory metallic alloy, in contact with the lens-shaping member flexible portions and first and second lens-supporting members. The first lens-supporting member has a proximal end region engaging the flexible member and the second lens-supporting member has a proximal end region connected to the lens-shaping member. A distal end region of at least the first lens supporting member is shaped for engaging, upon implanting the intraocular lens in an individual's eye, regions of the individual's eye that are responsive to contraction and relaxation of a ciliary muscle disposed in a ciliary body region of the individual's eye.
Preferably, the first and second lens supporting members are configured so their respective distal end regions are aligned with generally opposite regions of the ciliary body when the intraocular lens is implanted in the individual's eye. Also preferably each of the first and second lens supporting members are relatively rigid as compared with the dynamic lens, preferably being formed as is the lens shaping member from polymethyl methacrylate, with the second lens supporting member being rigidly connected to the lens-shaping member or the two may be constructed in one piece. The elastically flexible member is formed in a coil to encircle the flexible portions of the lens-shaping member.
The second lens supporting member may include a static, non-accommodating lens having an optical axis aligned with an optical axis of the dynamic lens.
In one embodiment, the intraocular lens is implanted in an individual's capsular bag from which a natural lens has been removed with the distal end regions of the first and second lens supporting members are configured for direct contact with the ciliary body. Correspondingly, the elastically flexible member and the flexible portion of the lens-shaping member each have a larger diameter unstressed condition and a smaller diameter stressed condition, and are configured for elastically returning to the larger diameter, unstressed conditions, thereby enabling the outer diameter of the dynamic lens to elastically expand to its non-accommodating condition, in response to the reduction of the compressive force applied to distal ends of the first and second lens support members by the ciliary body when the ciliary muscle relaxes.
Moreover, the elastically flexible member is constructed for tightening and squeezing the flexible portions of the lens-shaping member, thereby reducing the outer diameter of the dynamic lens by the lens-shaping member and increasing the surface curvature of the dynamic lens for achieving accommodation, in response to a compressive force applied to distal ends of the first and second lens support members by the ciliary body when the ciliary muscle contracts.
In another embodiment, the intraocular lens is implanted in an individual's capsular bag from which a natural lens has been removed with the distal ends of the first and second lens supporting members being configured for attachment to the capsular bag adjacent opposing ciliary body-connected zonules. In which case, the elastically flexible member is configured for being pulled to a larger diameter, stressed condition and the flexible portions of the lens-shaping member is configured for elastically returning to a larger diameter, unstressed condition, thereby enabling the outer diameter of said dynamic lens to attain its unstressed, non-accommodating condition, in response to an increase in tension applied to distal end regions of the first and second lens supporting members by the zonules when the ciliary muscle relaxes.
Correspondingly, the elastically flexible member is constructed for elastically contracting from the larger diameter stressed condition to a smaller diameter unstressed condition, thereby squeezing the flexible portions of the lens-shaping member to a smaller diameter stressed condition and reducing the outer diameter of the dynamic lens and increasing the surface curvature for achieving accommodation, in response to a release of tension applied to distal end regions of the first and second lens supporting members by the zonules when the ciliary muscle contracts.
In another embodiment, the intraocular lens is implanted in an anterior chamber of an individual's eye, with the distal end region of the first lens supporting member is configured for bearing against the ciliary body and with the second lens supporting member being configured for attaching to an iris region of the eye. The elastically flexible member and the flexible portion of the lens-shaping member each have a larger diameter unstressed condition and a smaller diameter stressed condition and are configured for elastically returning to the larger diameter, unstressed conditions, thereby enabling the outer diameter of the dynamic lens to elastically expand to its non-accommodating condition, in response to the reduction of the compressive force applied to the distal end region of the first lens supporting member by the ciliary body when the ciliary muscle relaxes. In such case, the elastically flexible member is constructed for tightening and squeezing the flexible portions of the lens-shaping member, thereby reducing the outer diameter of the dynamic lens by the lens-shaping member and increasing the surface curvature of the dynamic lens for achieving accommodation, in response to a compressive force applied to the distal end region of the first lens supporting member by the ciliary body when the ciliary muscle contracts.
The present invention can be more readily understood by a consideration of the following detailed description when taken in conjunction with the accompanying drawings, in which:
In the various FIGS., the same elements and features are given the same reference numbers. In the various variation, corresponding elements and features are given the same reference numbers as first set forth, followed by an “a”, “b”, “c”, and so on, as appropriate and/or as will otherwise be evident in the following DESCRIPTION.
DESCRIPTION OF THE PREFERRED EMBODIMENTThere is shown in plan view in
Comprising AIOL 20, as more particularly described below, is an elastically deformable dynamic, accommodating lens 26, the anterior surface curvature of which is changed in the manner described below to provide vision accommodation of the AIOL. Further comprising AIOL 20 are a first lens supporting member or dynamic haptic 28, a second lens supporting member or static haptic 30 and an elastically flexible dynamic lens spring coil or member 32 (
Dynamic lens 26, which is shown in
As described below relative to
Arcuate foot regions 52 and 54, respectively, of dynamic haptic 28 and static haptic 30 are anchored in capsular bag 22 and are thereby operatively connected by zonules 56 (which are connected to the periphery of the capsular bag) to a ciliary body 58 containing a ciliary muscle 60 that is depicted in its relaxed, non-accommodating state in
Shown in
It is, however, to be appreciated that dynamic lens 26 and/or static lens 70 may alternatively be formed as plano-convex lenses or meniscus (concave-convex) lenses (not shown), according to desired optical power to be provided by AIOL 20. By way of example, with no limitation being thereby implied or intended, dynamic lens 26 and static lens 70 in combination may be configured to provide between about −25 diopter and about +35 diopter correction. As depicted in
Formed as part of static haptic 30 is a slender, curved guide element 80 (
It will be appreciated that when ciliary muscle 60 in its relaxed state tension is created in zonules 56. Such zonule tension in pulls on haptics 28 and 30, thereby pulling spring coil 32 to its open, stressed state, thereby permitting dynamic lens 26 to resume its unstressed, non-accommodating, flatter state due to dynamic lens elasticity and the flexibility of static haptic rim 34.
As described above, when ciliary muscle 60 then relaxes, the resulting increased zonule tension pulls dynamic haptic 28 radially outwardly (direction of Arrow A,
As shown in the cross section of
As shown in
First, dynamic haptic 28 is depicted in plan view in
Shown in cross section in
Dynamic haptic 28 is preferably constructed from a material, for example, polymethyl methacrylate (PMMA), that is stiffer than that from which dynamic lens 26 is constructed. At least foot 52 and neck region 92 may be roughened or provided with small holes (not shown) to assist cell growth anchoring of the haptic inside capsular bag 22.
Second, static haptic 30 is depicted in
As shown in
As shown in
Preferred static, non-accommodating lens 70 may have a center thickness, t6, of about 4.0 mm and a posterior surface 102 may have a radius of curvature, R5, centered on optical axis 64, of about 200 mm (
It is within the scope of the present invention to provide a variation static haptic 30a (shown in cross section in
Preferably static haptics 30 and 30a are constructed from the same relatively stiff (as compared to dynamic lens 26) material, for example, PMMA, as above-described dynamic haptic 28 is constructed.
It is to be appreciated, however, that still other configurations of static haptic rim 34 are within the scope of the present invention.
First Variation AIOL of
AIOL 220, which implanted in capsular bag 22 in the manner of above-described AIOL 20, is shown, by way of example, having a biconvex dynamic lens 226 (shown in solid lines) and alternatively, also by way of illustration, having a concave-convex dynamic lens 220a (shown in broken lines).
A static haptic 228 of AIOL 220 is preferably constructed the same as above-described dynamic haptic 28 of AIOL 20. A static haptic 230 of AIOL 220 is preferably constructed the same as above-described static haptic 30 of AIOL 20, except that static haptic 230 is constructed without a rim or flange corresponding to rim or flange 34 of static haptic 30. In place of a rim or flange corresponding to rim or flange 34 of static haptic 30, AIOL 220 includes a dished flexible, dynamic lens-shaping member 202 that is centrally attached (as by laser tack welding) to static haptic 230 at a point 278 on optical axis 64 and thus can be considered part of the static haptic.
Dynamic lens-shaping member 202 is formed having a radius, R6, which may be about 14 mm centered on optical axis 64. Radius, R6, also defines the radius of posterior surface 276 of dynamic lenses 226 or 226a depending on the lens used in AIOL 220.
Formed around the periphery of lens-shaping member is a dynamic lens retaining rim 204 having an arcuate inner annular surface 208 that has the same diameter as the outside diameter of lenses 226 or 226a, as is above-described for inner annular groove 98 of static haptic rim 34 (
As shown in
AIOL 220 provides accommodation in the same manner as above described for AIOL 20 (
In the accommodation condition for which ciliary muscle 60 is contracted as depicted for AIOL 20 in
Second Variation AIOL of
It may in some instances be desirable or necessary to attach an aphakic AIOL implanted in capsular bag 22 directly to ciliary body 58, as depicted in
In order for AIOL 320 to provide accommodation in response to compression forces applied to dynamic haptic 328 and static haptic 330 by ciliary body 58 when ciliary muscle 60 contracts, spring coil 332 is, in its normal, non-accommodating, unstressed state made as depicted in
When ciliary muscle 60 relaxes, the compressive force from ciliary body 58 on dynamic haptic 328 is reduced permitting spring coil 332 to expand to its normal, unstressed state, thereby permitting dynamic lens 326 and static haptic rim 334 to elastically return to their flatter, non-accommodating condition.
It will be appreciated that the dynamic lens configuration described above with respect to
Third Variation AIOL of
It may in some instances be desirable to implant an AIOL in a phakic eye, for example, when its natural lens has lost the ability to provide complete or at least substantial accommodation but is otherwise healthy. Accordingly,
Third variation, phakic AIOL 420 is depicted in
Shown comprising third variation AIOL 420 are a dynamic haptic 428, a static haptic 430, a dynamic lens 426, a dynamic lens shaping member 202a and a spring coil 32. Dynamic haptic 428 is shaped generally like above-described dynamic haptic 28, except that for being formed having an elongated, curved neck region 492 that provides an offset distance, d3, of about 0.8 mm between haptic foot 452 that engages ciliary body 58 beneath ciliary muscle 60 and spring coil 32. Static haptic 430, shown by way of example as incorporating a plano-concave static lens 270a, is configured as disclosed in my prior U.S. Pat. No. 6,152,959, which is incorporated herein in its entirety by specific reference, for fixation to iris 66 forward of an intact natural lens 400.
Dynamic lens 426, shown by way of example as a biconvex lens is similar to above-described dynamic lens 226 (
Accommodation of phakic AIOL 420 is achieved by the compression of spring coil 32 installed around lens shaping member rib 206a in the manner described above for first variation, aphakic AIOL in response to contraction of ciliary muscle 60.
It will be appreciated that the dynamic lens configuration depicted in
It will also be appreciated that accommodation of both phakic AIOL 420 and aphakic AIOL 220 can be achieved by installing a spring coil, corresponding to spring coil 32 around the inside of lens shaping member rib 206 and 206a instead of around the outside thereof as depicted in respective
Although there have been described above an accommodating intraocular lens and several variations thereof, in accordance with the present invention for purposes of illustrating the manner in which the present invention maybe used to advantage, it is to be understood that the invention is not limited thereto. Consequently, any and all variations and equivalent arrangements that may occur to those skilled in the applicable art are to be considered to be within the scope and spirit of the invention as set forth in the claims that are appended hereto as part of this application.
Claims
1. An accommodating intraocular lens for implanting in an individual's eye, which comprises:
- a deformable elastic dynamic lens having a surface curvature;
- a lens-shaping member having flexible portions in contact with said dynamic lens for enabling deformation of said dynamic lens for changing said surface curvature;
- an elastically flexible member in contact with said lens-shaping member flexible portions, wherein said flexible member comprises a coil encircling said flexible portions of the lens-shaping member; and
- first and second lens supporting members, said first lens supporting member having a proximal end region engaging said flexible member and a distal end region, said second lens supporting member having a proximal end region connected to said lens-shaping member and a distal end region, the distal end region of the first lens supporting member being configured upon implantation to engage a first region of said individual's eye that is responsive to contraction and relaxation of a ciliary muscle disposed in a ciliary body region of said individual's eye.
2. The accommodating intraocular lens as claimed in claim 1, wherein the distal end region of the second lens supporting member is configured to engage a second region of said individual's eye, the first and second regions generally centered on a single meridian that passes through an optical axis of the dynamic lens.
3. The accommodating intraocular lens as claimed in claim 1, wherein each of said first and second lens supporting members are relatively rigid as compared with said dynamic lens.
4. The accommodating intraocular lens as claimed in claim 1, wherein said proximal end region of the second lens supporting member is rigidly connected to said lens-shaping member.
5. The accommodating intraocular lens as claimed in claim 1, wherein said lens-shaping member and said second lens supporting member are constructed in one piece.
6. The accommodating intraocular lens as claimed in claim 1, wherein said intraocular lens is implantable in an individual's capsular bag from which a natural lens has been removed and wherein the distal end regions of said first and second lens supporting members are configured for attachment to the capsular bag adjacent to opposing ciliary body-connected zonules.
7. The accommodating intraocular lens as claimed in claim 6, wherein said flexible portions of the lens-shaping member are responsive to increases of tension applied to said first and second lens supporting members by said zonules upon relaxation of said ciliary muscle by elastically returning to a larger diameter condition, thereby increasing a diameter of said dynamic lens and decreasing said surface curvature to attain a non-accommodating condition.
8. The accommodating intraocular lens as claimed in claim 6, wherein said flexible portions of the lens-shaping member are responsive to decreases of tension applied to said first and second lens supporting members by said zonules upon contraction of said ciliary muscle by elastically returning to a smaller diameter condition, thereby reducing a diameter of said dynamic lens and increasing said surface curvature to attain an accommodating condition.
9. The accommodating intraocular lens as claimed in claim 1, wherein said flexible member comprises a shape memory metallic alloy.
10. The accommodating intraocular lens as claimed in claim 1, wherein said dynamic lens comprises a silicone or acrylic material.
11. The accommodating intraocular lens as claimed in claim 1, wherein said lens-shaping member and said first and second lens supporting members comprise polymethyl methacrylate.
12. The accommodating intraocular lens as claimed in claim 1, wherein said second lens supporting member includes a static, non-accommodating lens having an optical axis aligned with an optical axis of said dynamic lens.
13. The accommodating intraocular lens as claimed in claim 1, wherein said intraocular lens is implantable in an individual's capsular bag from which a natural lens has been removed and wherein the distal end regions of said first and second lens supporting members are configured for direct contact with said ciliary body region.
14. The accommodating intraocular lens as claimed in claim 13, wherein said flexible member and said flexible portion of the lens-shaping member each have a larger diameter condition corresponding to an expanded diameter of the dynamic lens and a smaller diameter condition corresponding to a reduced diameter of the dynamic lens, and wherein said flexible member and said flexible portions of the lens-shaping member are configured for elastically returning to said smaller diameter conditions in response to said contraction of said ciliary muscle and for elastically returning to said larger diameter conditions in response to said relaxation of said ciliary muscle.
15. The accommodating intraocular lens as claimed in claim 13, wherein said elastically flexible member is responsive to a compressive force applied to the distal end regions of said first and second lens support members by said ciliary body region upon contraction of said ciliary muscle by squeezing said flexible portions of the lens-shaping member, thereby reducing a diameter of said dynamic lens and increasing said surface curvature of said dynamic lens.
16. The accommodating intraocular lens as claimed in claim 1, wherein said intraocular lens is implantable in an anterior chamber of the eye with the distal end region of said first lens supporting member directly contacting said ciliary body region, and with said second lens supporting member attached to an iris region of said eye.
17. The accommodating intraocular lens as claimed in claim 16, wherein said flexible member and said flexible portions of the lens-shaping member each have a larger diameter condition corresponding to an expanded diameter of the dynamic lens and a smaller diameter condition corresponding to a reduced diameter of the dynamic lens, and wherein said flexible member and said flexible portions of the lens-shaping member are responsive to reduction of a compressive force applied to the distal end region of said first lens supporting member by said ciliary body region upon relaxation of said ciliary muscle by elastically returning to said larger diameter conditions, thereby elastically expanding a diameter of said dynamic lens and elastically decreasing said surface curvature of said dynamic lens to a non-accommodating condition.
18. The accommodating intraocular lens as claimed in claim 17, wherein said flexible member is responsive to a compressive force applied to said first lens supporting member by said ciliary body region upon contraction of said ciliary muscle by squeezing said flexible portions of the lens-shaping member, thereby elastically reducing the diameter of said dynamic lens, and elastically increasing said surface curvature of said dynamic lens to an accommodating condition.
19. An accommodating intraocular lens, comprising:
- a lens having a deformable surface; and
- first and second members coupled together to transfer force from the ciliary muscle to the lens, said second member comprising a strand forming a loop having a diameter which encircles at least a central portion of the lens, said first member responsive to action of the ciliary muscle to apply a first force to said second member such that the diameter of the loop changes, said second member applying a second force which acts on the circumference of the lens in response to said first force such that both the circumference and the curvature of the lens change, wherein the first member comprises a forked member that splays in response to contractions of the ciliary muscle to reduce the compression of the second member.
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Type: Grant
Filed: Dec 10, 2001
Date of Patent: Aug 29, 2006
Patent Publication Number: 20030109926
Inventor: Valdemar Portney (Tustin, CA)
Primary Examiner: Bruce Snow
Assistant Examiner: Cheryl Miller
Attorney: Knobbe, Martens, Olson & Bear, LLP
Application Number: 10/016,705
International Classification: A61F 2/16 (20060101);