Means For Supplying, Or Permitting Inhalation Of, Separate Streams Of Treating Agent/respiratory Gas Mixture Through Nasal Passages Patents (Class 128/203.22)
  • Patent number: 11707592
    Abstract: A device and method of generating an enriched gas within a nasal vestibule of a patient includes a housing, a chamber, a chamber inlet, a pump, a molecular sieve bed, a release outlet, and a breath duct. The chamber is configured to be received within the nasal vestibule. The pump is configured to direct an ambient air from an ambient environment into the chamber. The molecular sieve bed is positioned within the chamber and configured to collect a predetermined molecule from the ambient air thereby generating the enriched gas. The release outlet is configured to discharge the enriched gas from the chamber into the nasal vestibule. The breath duct longitudinally extends through the housing such that the breath duct is configured to fluidly communicate a fluid flow through the housing for nasal breathing by the patient while the chamber is positioned within the nasal vestibule.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: July 25, 2023
    Assignee: Worldwide Health Innovations, LLC
    Inventor: Keavash Darren Assani
  • Patent number: 11497864
    Abstract: An electronic vaporizer is provided. The electronic vaporizer includes a cartridge that facilitates provision of a vaporized solution to an individual. The cartridge includes a housing that includes an interior, wherein the housing is one of a polymer housing or a ceramic housing. The cartridge also includes a heating element located in the interior of the housing, wherein the heating element is configured to vaporize a solution for oral provision to the individual. The vaporizer may also include a power harvesting device operative to acquire energy from the environment for use with powering the heating element.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: November 15, 2022
    Assignee: FUMA INTERNATIONAL, LLC
    Inventors: Gregory D. Conley, Daniel C. Hillenbrandt
  • Patent number: 11471714
    Abstract: A nasal device for filtering breathing air includes an elongated support member, and two rounded holder members, each arranged at a respective end of the elongated support member. The holder members are adapted to be inserted into a nostril with a distal end directed into the nostril, and a proximal end adjacent the nostril openings. The holder members include a bell-shaped cross-section in at least one plane in a distal-proximal extension.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: October 18, 2022
    Assignee: NoseOption AB
    Inventors: Mikael Hellman, Alexis Ruin
  • Patent number: 11357945
    Abstract: A nasal pad for respiratory mask and a respiratory mask. The nasal pad comprises a nasal pad body and nasal plugs. Each nasal plug comprises a nasal plug body. The nasal plug bodies are fixedly connected to the nasal pad body. The nasal pad body comprises extend-retract adjustment sections. The extend-retract adjustment sections are provided with an extended length and a retracted length. The extend-retract adjustment sections are configured in a way that the length thereof can be adjusted between the extended length and the retracted length, thus varying the distance between the two nasal plug bodies. One purpose of the nasal pad is for use in the respiratory mask.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: June 14, 2022
    Assignee: BMC MEDICAL CO., LTD.
    Inventors: Yifeng Zhan, Zhi Zhuang
  • Patent number: 11173269
    Abstract: An adaptor for a respiratory assistance system delivers aerosols to a patient. The adaptor is lightweight with a small footprint to increase patient comfort. The adaptor has a nozzle and a sealing mechanism to maintain pressure therein regardless of whether the nozzle is inserted into the adaptor. The adaptor is configured to connect to medical tubing and a medicament delivery device.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: November 16, 2021
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: David John Sims, David Robert Kemps
  • Patent number: 11166835
    Abstract: A rhinoplasty appliance is provided that may be custom-molded to a patient's nasal anatomy, including the nostrils, to maintain the corrected contour of the nostrils after rhinoplastic surgery. The rhinoplasty appliance may include a support wire; a first and second wire flanges; a first and second nostril insertion portions, each having a passage and an aperture to permit flow of air and drainage; a connecting structure to maintain the position of the nostril insertion portions in relation to each other, and to provide support and protection for the columella. The first and second wire flange may help to secure the rhinoplasty appliance in position on the patient's face, and improve retention of the first and second nostril insertion portions in the patient's nostrils. The support wire may be provided as added support for the connecting structure.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: November 9, 2021
    Inventor: Martha L. Mejia
  • Patent number: 11154671
    Abstract: A nasal device comprises a first component and a second component and a connector for coupling the first component to the second component and configured to span a nasal septum of the user. The first component comprises a body for insertion into a nasal cavity of a nose of a user. The body comprises a loop structure having an inner surface defining an aperture and a reverse outer surface, the loop structure being configured for alignment with an interior contour of a nasal passage of the nose, a platform spanning the aperture defined by the inner surface of the loop structure, and a valve mechanism disposed on the platform for controlling fluid flow through the aperture. The first component further comprises at least one mount extending from the body.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: October 26, 2021
    Assignee: ASAP Breatheassist Pty Ltd
    Inventors: Justin Robert Armistead, Michael Ralph Burgess Johnson, Toby James Hartley
  • Patent number: 11077275
    Abstract: A breathing arrangement includes a patient interface, at least one inlet conduit, and a headgear assembly. The patient interface includes a mouth covering assembly including a cushion structured to sealingly engage around exterior of a patient's mouth in use, a nozzle assembly including a pair of nozzles structured to sealingly engage within nasal passages of a patient's nose in use, and a flexible element connecting the mouth covering assembly and the nozzle assembly. The at least one inlet conduit is structured to deliver breathable gas into at least one of the mouth covering assembly and the nozzle assembly for breathing by the patient. The headgear assembly is removably connected to at least one of the mouth covering assembly and the nozzle assembly so as to maintain the mouth covering assembly and the nozzle assembly in a desired position on the patient's face.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: August 3, 2021
    Assignee: ResMed Pty Ltd
    Inventors: Aaron Samuel Davidson, Michael Kassipillai Gunaratnam, Susan Robyn Lynch, Milind Chandrakant Raje, Gary Christopher Robinson, Steven John Lubke, Gregory Scott Smart, Philip Rodney Kwok, Rupert Christian Scheiner
  • Patent number: 10953172
    Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least some of the example embodiments are methods including: titrating a patient with therapeutic gas during a period of time when a flow state of breathing orifices is in a first state, the titrating results in a prescription titration volume; and then delivering the prescription titration volume of therapeutic gas to the patient when the flow state of the breathing orifices is in a second state different than the first state, the delivering only to the breathing orifices open to flow.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: March 23, 2021
    Assignee: Incoba, LLC
    Inventors: Alonzo C. Aylsworth, Lawrence C. Spector
  • Patent number: 10744291
    Abstract: A nasal assembly for delivering gas under positive pressure to a patient for treatment of sleep disordered breathing includes an air connector to be connected to an air supply tube for delivering a supply of gas. The air connector is to be positioned on top of the head. A nasal interface engages the patient's nose to direct the breathable gas to the patient's nose. A pair of flexible side portions support the nasal interface in a desired position on the patient's face. Each side portion has a conduit with a top portion and a bottom portion. Each conduit is arranged between the patient's eye and ear. A central portion joins the top portions of the conduits. The air connector is pivotally connected to each of the supply tube and the central portion.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: August 18, 2020
    Assignee: ResMed Pty Ltd
    Inventors: Philip Rodney Kwok, Donald Darkin
  • Patent number: 10716908
    Abstract: An infant positive airway pressure (PAP) or continuous positive airway pressure (CPAP) device and related patient interface and system, which can provide a flow of breathing gas to the patient interface. The device can be incorporated into the patient interface and includes at least one interior passage in the shape of a nozzle having a throat, a first portion upstream of the throat and a second portion downstream of the throat relative to the flow of breathing gas. The passage has a vent opening within the second portion and the interior passage defines a continuously curved surface extending between the throat and the vent opening. The second portion of the nozzle preferably is divergent and the first portion can be convergent or non-convergent (e.g., constant cross-section).
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: July 21, 2020
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Callum James Thomas Spence, Rachael Porter, Craig Karl White, Alicia Jerram Hunter Evans
  • Patent number: 10524515
    Abstract: An aerosol-generating device may include a housing having flexible portion along its length. The flexible portion is configured to transition between a relaxed or unloaded configuration and a flexed or deflected configuration. A flexible heating element and mouthpiece may also be disposed in the housing. When the housing is in a relaxed or unloaded configuration, the flexible heating element and the mouthpiece are at least partially longitudinally aligned with the flexible portion of the housing.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: January 7, 2020
    Assignee: Altria Client Services LLC
    Inventors: Rui Nuno Batista, Stephane Antony Hedarchet
  • Patent number: 10518058
    Abstract: A nasal assembly for delivering breathable gas to a patient includes a frame having an integrally formed first connector portion. A nozzle assembly includes a gusset or base portion and a pair of nozzles. At least one inlet conduit is structured to deliver breathable gas into the frame and nozzle assembly for breathing by the patient. A pair of second connector portions are removably and rotatably connected to respective first connector portions of the frame and are in communication with respective inlet conduits, e.g., directly or via angle connectors. A headgear assembly is removably connected to the pair of second connector portions and/or the angle connectors so as to maintain the frame and the nozzle assembly in a desired adjusted position on the patient's face.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: December 31, 2019
    Assignee: ResMed Pty Ltd
    Inventors: Michael Kassipillai Gunaratnam, Philip Rodney Kwok, Robin Garth Hitchcock, Lee James Veliss, Memduh Guney, Richard Sokolov, Perry David Lithgow, Donald Darkin, Susan Robyn Lynch
  • Patent number: 10426652
    Abstract: A nasal apparatus which is placed in a nostril in order to provide several respiratory benefits includes a nasal insert having a hub, a plurality of arched legs, and a lateral face. Each of the plurality of arched legs comprises a proximal end and a free end positioned opposite each other, wherein the proximal end is adjacently connected to the hub. The plurality of arched legs is positioned around the hub forming a nasal shell structure in the shape of an inner nasal surface of the nostril, wherein the nasal insert is flexible as to apply pressure to the inner nasal surface. The nasal apparatus may further include a bridge and a subsequent nasal insert, wherein the bridge is adjacently connected to both the nasal insert and the subsequent nasal insert, and is positioned in between the nasal insert and the subsequent nasal insert.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: October 1, 2019
    Assignee: Nasal Medical Limited
    Inventors: Martin O'Connell, Keith Yeager
  • Patent number: 10322304
    Abstract: A nasally inserted air filter including a plurality of filter materials in a compact housing, or alternatively, a series of electrically conducting plates connected to a battery in a compact housing. The filters may include a radio frequency identification system to interact with a user's cell phone to transmit and analyze important data.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: June 18, 2019
    Inventors: Sandy Kronenberg, Adam Kehres
  • Patent number: 10293132
    Abstract: The invention concerns a nasal cannula assembly (10) adapted to deliver gases to a patient comprising a first compartment (1) and a second compartment (2) separated by a separation wall (6); a pair of nasal prongs (5) in fluid communication with the first compartment (1); the first compartment (1) comprising a first inlet (11) for introducing a first gas into said first compartment (1); the second compartment (2) comprising a second inlet (2) for introducing a second gas into said second compartment (2); and the separation wall (6) comprising at least one flow restriction element (35) for controlling the passage of gas from the second compartment (2) to the first compartment (1).
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: May 21, 2019
    Assignee: L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude
    Inventor: Andrew Martin
  • Patent number: 10195088
    Abstract: A nose compression device for treating a nosebleed of a person. The device includes a wire frame having a straight middle section and two end sections angled with respect to the middle section. The device also has a body attached to the wire frame, and two nasal sponges attached to the body for insertion into the person's nasal passages. The end sections are wider than the user's nose, and the device is slid upward on the user's face so that the nasal sponges enter the user's nasal passages. The end sections are then bent inward to a pinch position where they pinch the upper lateral side surfaces of the user's nose. The nasal sponges can be pre-treated with medication to further stop the nosebleed. Ice pack may also be provided that extends over the compression device. The combination of compression, medication, and cooling facilitate treatment of the nosebleed.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: February 5, 2019
    Assignee: Emergency Medical Innovation LLC
    Inventors: Elizabeth P. Clayborne, Neal K. Sikka, Romil Patel
  • Patent number: 10155096
    Abstract: A supplemental gas delivery device is described for a mask assembly having at least one supplemental gas port, the at least one supplemental gas port including an aperture in communication with an interior of the mask assembly. The mask assembly may include an aperture communicating with an interior of the mask assembly, and a cannula for communicating with the supplemental gas port. The cannula is positioned to deliver supplemental gas adjacent to the patient's nares and/or mouth, to increase an efficacy of treatment for the patient by more directly applying the flow of supplemental gas to the patient's nares. An optional bridging portion may be included to provide a connection between supplemental gas port and the cannula.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: December 18, 2018
    Assignee: RESMED LIMITED
    Inventor: Amal Shirley Amarasinghe
  • Patent number: 10076614
    Abstract: A nasal delivery device for delivering substance to a nasal cavity of a subject comprises: a housing (15); a nosepiece (17) for fitting to a nasal cavity of the subject; a mouthpiece (19) through which the subject in use exhales; and a flexible coupling (20) which couples the mouthpiece to the housing, wherein the flexible coupling provides for asymmetric translation of the mouthpiece relative to the nosepiece.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: September 18, 2018
    Assignee: OptiNose AS
    Inventors: Per Gisle Djupesland, Joseph Gordon, Michael Leclerc, Ramy A Mahmoud, Shane Siwinski
  • Patent number: 9895508
    Abstract: A mouth cushion for a mask system includes a side wall, a membrane extending from the side wall and adapted to form a continuous seal around an exterior of a patient's mouth in use, and at least one support strut or rib provided to the side wall. The at least one support strut or rib is at least partially determinative of a deflection characteristic of the mouth cushion.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: February 20, 2018
    Assignee: RESMED LIMITED
    Inventors: Rupert Christian Scheiner, Scott Alexander Howard, Gregory Scott Smart, Christopher Scott Skipper, Steven John Lubke, Timothy Shawn Nelson
  • Patent number: 9883736
    Abstract: A portable deployable table is a device that may be easily mounted to and removed from a surface or structure. The device includes a housing with at least one telescopic arm fixed within the housing. A table frame and a planar table top are hingedly connected to the at least one telescopic arm and may be deployed after being extended from within the housing. The table frame and the planar table top are contained within the housing when the device is not in use. At least one adjustable mounting brace is connected to the exterior of the housing, allowing the housing to be mounted to a surface or structure and fixed in place. The housing may be closed via a housing lid that covers the interior of the housing.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: February 6, 2018
    Inventor: Jamal Dashti
  • Patent number: 9636043
    Abstract: A system for sampling exhaled breath and for supply of a gas, the system comprising: a gas delivery cannula comprising at least one nasal prong for insertion into a nostril, the nasal prong comprising a distal end; an exhaled breath sampling cannula for insertion into the nostril, the exhaled breath sampling cannula comprising a distal end; and a connector for coupling the gas delivery cannula to the exhaled breath sampling cannula, such that the distal end of the exhaled breath sampling cannula is disposed deeper in the nostril than the distal end of the nasal prong, to reduce dilution of sampled exhaled breath by delivered gas. The connected is configured to facilitate adjustability of an insertion depth of the exhaled breath sampling cannula into said nostril.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: May 2, 2017
    Assignee: Oridion Medical 1987 Ltd.
    Inventors: Gershon Levitsky, David Lain, Joshua Lewis Colman
  • Patent number: 9468727
    Abstract: A nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a delivery unit for delivering a flow entraining a substance to one nostril of a subject, the delivery unit including a nosepiece for fitting to a nostril of the subject; and a flow resistor unit for fitting to the other nostril of the subject, the flow resistor unit including a progressive resistor for progressively providing an increasing flow resistance to the delivered flow.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: October 18, 2016
    Assignee: OptiNose AS
    Inventor: Per Gisle Djupesland
  • Patent number: 9308334
    Abstract: An inhaler, the inhaler including a body (104) and a cartridge (106), the cartridge comprising a dose storage portion (122) and an airway (124), the dose storage portion being suitable for containing a plurality of doses of an inhalable medicament, the airway including a mouthpiece (128) at an end thereof, the inhaler device configured and arranged such that a dose of inhalable medicament from the dose storage portion can be accessed and arranged in a delivery configuration for delivery to a user through the airway upon inhalation through the mouthpiece by the user, the inhaler characterized in that the cartridge is replaceably removable from the body.
    Type: Grant
    Filed: September 28, 2011
    Date of Patent: April 12, 2016
    Assignee: Novartis AG
    Inventors: Steven Dudley, John Palmer-Felgate, Sean Reynolds, Iain Breakwell, Jon Jamin, Steve Augustyn, Grant Smetham, Laura Kaye, John McGarva
  • Patent number: 9272115
    Abstract: A respiratory therapy device comprises a pneumatic control unit connectable to a source of medical grade oxygen for supplying oxygen to a first control unit outlet port at a first set of conditions and to a second control unit outlet port at a second set of conditions. First and second transfer conduits are in fluid communication with the first and second outlet ports. Each transfer conduit defines at least part of a flowpath to destination. Each flowpath includes a filter. A related filtration module comprises a filter housing defining two or more filter compartments. The housing has an input side with a gas inlet in fluid communication with each of the filter compartments and a gas outlet in fluid communication with each of the filter compartments. A filter element resides in each of the compartments intermediate the gas inlet to the compartment and the gas outlet from the compartment.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: March 1, 2016
    Assignee: Hill-Rom Services PTE LTD.
    Inventors: John Alan Bobey, Brian E. Byrd
  • Patent number: 9220860
    Abstract: A breathing arrangement includes a patient interface, at least one inlet conduit, and a headgear assembly. The patient interface includes a mouth covering assembly including a cushion structured to sealingly engage around exterior of a patient's mouth in use, a nozzle assembly including a pair of nozzles structured to sealingly engage within nasal passages of a patient's nose in use, and an element connecting the mouth covering assembly and the nozzle assembly. The at least one inlet conduit is structured to deliver breathable gas into at least one of the mouth covering assembly and the nozzle assembly for breathing by the patient. The headgear assembly is removably connected to at least one of the mouth covering assembly and the nozzle assembly so as to maintain the mouth covering assembly and the nozzle assembly in a desired position on the patient's face.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: December 29, 2015
    Assignee: ResMed Limited
    Inventors: Aaron Samuel Davidson, Michael Kassipillai Gunaratnam, Susan Robyn Lynch, Milind Chandrakant Raje, Gary Christopher Robinson, Steven John Lubke, Gregory Scott Smart, Philip Rodney Kwok, Rupert Christian Scheiner
  • Patent number: 9155855
    Abstract: Mouthpiece (1) having vestibular shield (21) overlapping a user's teeth and gums, gases passageway means extending through said vestibular shield allowing for the passage of said gases through mouthpiece and extra oral sealing (25) means associated with gases passageway, said passageway in use causes gases to be diffused (outlets 23, 24) when exiting from gases passageway. Mouth piece may have a noseflap to seal the user's nose or provide a passageway for user's nasal passages. Mouthpiece may have adjustment means to alter distance between said vestibular shield and said extra-oral sealing means.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: October 13, 2015
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Adam Alexander Tebbutt, Blair Albert Neal, Lewis George Gradon, Alastair Edwin McAuley, Mark Joseph Haycock
  • Publication number: 20150144129
    Abstract: A method of delivering a substance, such as one or more of a triptan, a nasal steroid or carbon dioxide gas, to the nasal cavity of a subject, in particular for the treatment of headaches, for example, migraine, or rhinosinusitis, for example, chronic rhinosinusitis, optionally with polyps, the method comprising the steps of fitting a nosepiece to one nostril of the subject, delivering the substance through the nosepiece to the posterior region of the nasal cavity of the subject.
    Type: Application
    Filed: June 25, 2014
    Publication date: May 28, 2015
    Inventors: Per Gisle DJUPESLAND, Ramy A. MAHMOUD, John MESSINA
  • Publication number: 20150118335
    Abstract: A method, apparatus and kit have been discovered which utilize pulsed odorants, drugs, medicaments, and combinations thereof to treat diseases, symptoms of diseases and the like. In one form, the pulsed odorants, drugs, medicaments, and combinations thereof can be used to regenerate the connections of the neurons of the brain and central nervous system in the treatment of symptoms of such person afflicted with neuro-disorders, such as caused by disease or trauma.
    Type: Application
    Filed: January 7, 2015
    Publication date: April 30, 2015
    Inventor: Evaristus A. Nwulia
  • Patent number: 9004071
    Abstract: One embodiment provides a nasal guide. The nasal guide includes a pair of supports adapted to be positioned adjacent nostrils of a nose of a patient. The nasal guide includes a bridge connecting the pair of supports. The bridge is usable to adjust positioning of the pair of supports. Each of the pair of supports forms one or more lumens configured to receive one or more medical instruments. The one or more lumens are shaped for insertion into a nasal cavity of the nose.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: April 14, 2015
    Inventors: Ian Joseph Alexander, Brian Dean Owens
  • Publication number: 20150094609
    Abstract: Methods and systems are provided for a device having a first member and a second member coupled to the first member where the second member is configured to modify a configuration of a human or animal orifice or conduit. In some embodiments, the first member is a shaft and the second member is an inflatable membrane system configured to facilitate inflation or deflation of the inflatable membrane system. In some embodiments, the first member is a U-shaped member with end members configured for insertion to an internal nasal valve. Other embodiments are disclosed.
    Type: Application
    Filed: September 29, 2014
    Publication date: April 2, 2015
    Inventor: Alan L. Jacobson
  • Publication number: 20150065904
    Abstract: The present invention provides a system and method for delivery of nitric oxide to the upper respiratory tract without resulting in nitric oxide delivery to the lungs. In certain embodiments, the invention comprises the use of a flow sensor to sense the exhalation of the subject, and delivering a nitric oxide containing gas upon sensed exhalation.
    Type: Application
    Filed: August 27, 2013
    Publication date: March 5, 2015
    Applicant: 12th Man Technologies, Inc.
    Inventors: Alex Stenzler, Steve Han
  • Publication number: 20150013678
    Abstract: In one embodiment, a nasal cannula is shaped to fit within a user's nares, where the nasal cannula includes at least one prong allowing high flow delivery of humidified gases and creates positive airway pressure in the patient's airway. The prongs have angled ends such that, in use, gases flowing through the prongs are directed to the user's nasal passages. The nasal cannula body is partially swivelling and preferably has a ball joint connector. In another embodiment the nasal cannula may have at least one flared end prong that preferably seals within a patient's nare.
    Type: Application
    Filed: July 16, 2014
    Publication date: January 15, 2015
    Inventors: Alastair Edwin McAuley, Craig Robert Prentice, Oliver Gleeson
  • Publication number: 20150007817
    Abstract: A mixer-heater device provides controllable reduction in aerosol droplet size. Additionally, an intermittent delivery mode for administering an aerosol to a patient may take into account patient expiration and reduce aerosol losses without prolonging treatment time. Depositional losses in aerosol delivery systems may be reduced by streamlining the three dimensional geometry of conduits which change stream direction or flow path diameter. Ventilation systems may also benefit from streamlined components, in particular Y-connectors, with resulting advantages such as reduced rebreathed CO2.
    Type: Application
    Filed: July 8, 2014
    Publication date: January 8, 2015
    Applicant: Virginia Commonwealth University
    Inventors: Philip Worth Longest, Michael Hindle
  • Publication number: 20150000661
    Abstract: The invention concerns a nasal cannula assembly (10) adapted to deliver gases to a patient comprising a first compartment (1) and a second compartment (2) separated by a separation wall (6); a pair of nasal prongs (5) in fluid communication with the first compartment (1); the first compartment (1) comprising a first inlet (11) for introducing a first gas into said first compartment (1); the second compartment (2) comprising a second inlet (2) for introducing a second gas into said second compartment (2); and the separation wall (6) comprising at least one flow restriction element (35) for controlling the passage of gas from the second compartment (2) to the first compartment (1).
    Type: Application
    Filed: June 28, 2013
    Publication date: January 1, 2015
    Applicant: American Air Liquide, Inc.
    Inventor: Andrew MARTIN
  • Publication number: 20150000659
    Abstract: The invention concerns a nasal cannula assembly (10) adapted to deliver gases to a patient comprising a first compartment (1) and a second compartment (2) separated by a separation wall (6); a pair of nasal prongs (5) in fluid communication with the first compartment (1); the first compartment (1) comprising a first inlet (11) for introducing a first gas into said first compartment (1); the second compartment (2) comprising a second inlet (2) for introducing a second gas into said second compartment (2); and the separation wall (6) comprising at least one valve element (3) for controlling the passage of gas from the second compartment (2) to the first compartment (1). The invention concerns also a breathing assistance apparatus comprising a source of NO gas, and said nasal cannula assembly (10) in fluid communication with said source of NO gas.
    Type: Application
    Filed: June 28, 2013
    Publication date: January 1, 2015
    Inventor: Andrew MARTIN
  • Publication number: 20150000658
    Abstract: The invention concerns a nasal cannula assembly (10) adapted to deliver gases to a patient comprising a first compartment (1) and a second compartment (2) separated by a separation wall (6); a pair of nasal prongs (5) in fluid communication with the first compartment (1); the first compartment (1) comprising a first inlet (11) for introducing a first gas into said first compartment (1); the second compartment (2) comprising a second inlet (2) for introducing a second gas into said second compartment (2); and the separation wall (6) comprising at least one valve element (3) for controlling the passage of gas from the second compartment (2) to the first compartment (1). The invention concerns also a breathing assistance apparatus comprising a source of NO gas, and said nasal cannula assembly (10) in fluid communication with said source of NO gas.
    Type: Application
    Filed: June 28, 2013
    Publication date: January 1, 2015
    Inventor: Andrew MARTIN
  • Publication number: 20150000660
    Abstract: The invention concerns a nasal cannula assembly (10) adapted to deliver gases to a patient comprising a first compartment (1) and a second compartment (2) separated by a separation wall (6); a pair of nasal prongs (5) in fluid communication with the first compartment (1); the first compartment (1) comprising a first inlet (11) for introducing a first gas into said first compartment (1); the second compartment (2) comprising a second inlet (2) for introducing a second gas into said second compartment (2); and the separation wall (6) comprising at least one flow restriction element (35) for controlling the passage of gas from the second compartment (2) to the first compartment (1).
    Type: Application
    Filed: June 28, 2013
    Publication date: January 1, 2015
    Applicant: American Air Liquide, Inc.
    Inventor: Andrew MARTIN
  • Patent number: 8910629
    Abstract: A delivery device for providing therapeutic gas to the nasal airway of a subject, the delivery device comprising: a nosepiece (21) for fitting to one nostril of the subject; a mouthpiece (23) through which the subject in use exhales and which is fluidly connected to the nosepiece (21); and a scrubber (27) which is operative at least to reduce the concentration of at least one gas from an exhaled breath of the subject as delivered through the mouthpiece (23) and provide a gas flow to the nosepiece (21) which has an increased concentration of at least one other,” therapeutic gas which provides a therapeutic effect.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: December 16, 2014
    Assignee: OptiNose AS
    Inventors: Per Gisle Djupesland, Roderick Peter Hafner
  • Patent number: 8881722
    Abstract: Various embodiments of the invention may provide a breathing and/or anesthetic unit that is portable, compact, inexpensive, and convenient, and which may expedite medical procedures by allowing a health care provider to quickly sedate a patient. Such a unit may be ideal for minor medical procedures needing mild or moderate analgesia/sedation (e.g., <30 minutes) in various fields. Such a unit may include (i) a handheld gas supply container including a therapeutic amount of anesthetic gas; (ii) a mask; (iii) a single-use, uninterruptable flow coupler to couple the mask to the supply container; and (iv) a handheld, self-contained, recovery gas container, including a negative pressure, coupled to the mask.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: November 11, 2014
    Inventor: Erin Bird
  • Publication number: 20140311482
    Abstract: The disclosure describes an aerosolizer with (i) means sized for intranasal or paranasal insertion that produces an aerosol from a material for delivery in close proximity to the upper airways, and (ii) the material comprising one or more proinflammatory cytokine inhibitor(s).
    Type: Application
    Filed: January 24, 2014
    Publication date: October 23, 2014
    Inventor: Roy C. Levitt
  • Publication number: 20140311483
    Abstract: A delivery device includes a toroidal shaped housing defining an interior chamber and a central open space. The housing includes an input port communicating with the interior chamber and a delivery port positioned on an inner periphery of the housing. The delivery port is in fluid communication between the interior chamber and the central open space. The delivery port is spaced from the input port, which is adapted to receive an aerosolized medicament. In another aspect, a kit includes an outer ring-like housing component and a plurality of differently configured inner ring-like housing components mateable with the outer ring-like housing to form a holding chamber. A method of delivering an inhalable substance includes positioning a nose and a mouth of a user in a central opening defined by a ring-like housing, inhaling through the nose, and orally soothing the user with a soothing device located in the central opening.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 23, 2014
    Applicant: Trudell Medical International
    Inventors: DANIEL ENGELBRETH, Martin P. Foley, Jerry Grychowski, James Schmidt, Jennifer Pevler
  • Publication number: 20140299129
    Abstract: The present invention generally relates to, amongst other things, systems, devices, materials, and methods that can improve the accuracy and/or precision of nitric oxide therapy by, for example, reducing the dilution of inhaled nitric oxide (NO). As described herein, NO dilution can occur because of various factors. To reduce the dilution of an intended NO dose, various exemplary nasal cannulas, pneumatic configurations, methods of manufacturing, and methods of use, etc. are disclosed.
    Type: Application
    Filed: June 23, 2014
    Publication date: October 9, 2014
    Inventors: Craig Flanagan, Simon Freed, John Klaus, Thomas Kohlmann, Martin D. Meglasson, Manesh Naidu, Parag Shah
  • Patent number: 8851069
    Abstract: A dry powder inhaler comprises an airway (1) along which, in use, air is drawn from an upstream, inlet end (2) to a downstream, outlet end (3). The airway (1) includes a medicament presentation region (4) at which, in use, a dose of medicament is presented to the airway (1), a primary air inlet (10), and a barrel (5) extending from the medicament presentation region (4) to the outlet end (3) of the airway (1). The inlet end of the barrel (5) is of reduced internal dimension relative to the medicament presentation region (4) and relative to the outlet end of the barrel (5), such that the inlet end of the barrel (5) constitutes a constriction of the airway (1). At least one secondary air inlet (11) is disposed such that, in use, air enters the airway (1) from the secondary air inlet (11) in a direction that is substantially orthogonal to the direction of flow of air along said barrel (5).
    Type: Grant
    Filed: April 21, 2005
    Date of Patent: October 7, 2014
    Assignee: Innovata Biomed Limited
    Inventors: Weidong Peng, Christopher Andrew Townsend
  • Publication number: 20140246023
    Abstract: An improved adjustable nasal dilator device (1) insertable within the nasal cavity of a human being to improve the flow of air through the nasal passage. The device includes a body (2) comprising a top (3) and bottom (4) frame ends interconnected by a series of spaced flexible ribs (5). The top and bottom frame ends are open and substantially circular, and the diameter of the bottom frame end is greater than the corresponding diameter of the top frame end to provide a body shape for convenient insertion within a nasal cavity.
    Type: Application
    Filed: May 28, 2008
    Publication date: September 4, 2014
    Inventor: Paz Maryanka
  • Publication number: 20140202456
    Abstract: A nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a delivery unit for delivering a flow entraining a substance to one nostril of a subject, the delivery unit including a nosepiece for fitting to a nostril of the subject; and a flow resistor unit for fitting to the other nostril of the subject, the flow resistor unit including a progressive resistor for progressively providing an increasing flow resistance to the delivered flow.
    Type: Application
    Filed: December 2, 2013
    Publication date: July 24, 2014
    Applicant: OPTINOSE AS
    Inventor: Per Gisle Djupesland
  • Patent number: 8763604
    Abstract: Apparatus, methods, and kits for treating symptoms associated with common ailments, such as headaches, rhinitis, asthma, epilepsy, nervous disorders and the like, are provided. The apparatus comprises dispensers for carbon dioxide and other therapeutic gases. The methods comprise delivering small volumes of these gases to patients in a manner where the gas infuses into a body region in order to bathe the mucous membranes therein. It has been found that even very short exposure of patients to small volumes and high concentrations of such gases can provide significant relief from symptoms.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: July 1, 2014
    Assignee: Capnia, Inc.
    Inventors: Ned S. Rasor, Julia S. Rasor
  • Publication number: 20140166009
    Abstract: Described are nasal cannulas that improve the precision of the delivered dose for nitric oxide therapy by reducing the dilution of nitric oxide. The nasal cannulas may reduce the total volume and potential for retrograde flow during nitric oxide therapy through the design of the specific dimensions of the flow path and/or having check valves in the nitric oxide delivery line and/or having a flapper or umbrella valve dedicated to nitric oxide delivery. The nasal cannulas may also use materials that limit oxygen diffusion through the cannula walls. The nosepiece for these cannulas may be manufactured by a molding technique.
    Type: Application
    Filed: December 4, 2013
    Publication date: June 19, 2014
    Applicant: INO Therapeutics LLC
    Inventors: Craig Flanagan, Simon Freed, John Klaus, Thomas Kohlmann, Martin D. Meglasson, Manesh Naidu, Parag Shah
  • Publication number: 20140158127
    Abstract: An apparatus can include a nasal cannula assembly, which includes a face piece. The face piece includes a plenum portion and a nasal interface portion. The plenum portion is configured to be coupled to a supply line and defines a flow path configured to receive an aerosol flow from the supply line. The nasal interface portion includes a first delivery protrusion and a second delivery protrusion. The first delivery protrusion is configured to convey a first portion of the aerosol flow to a first nostril, and the second delivery protrusion is configured to deliver a second portion of the aerosol flow to a second nostril. The plenum portion includes a sidewall having a curved surface configured to redirect the second portion of the aerosol flow towards the second delivery protrusion. The sidewall is configured to isolate the flow path from a volume downstream from the second delivery protrusion.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 12, 2014
    Applicant: PARION SCIENCES, INC.
    Inventors: Paul BOUCHER, Brian M. BUTTON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, Stuart Robert ABERCROMBIE, Michael Richard BURCHER, Mark Jeffrey EDHOUSE, Jamie Alan GREENWOOD, Emma Jane HASLER, Guy Conwyn Julian MOSELEY, David William SMITH, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
  • Patent number: RE45404
    Abstract: Improvement for the device to deliver the powdery medicine into nasal cavities in which a capsule setting/detaching part 40 is built drawably in the capsule housing/holding part 30, and cutting blades 60A, 60B are built in both axial ends of the capsule setting/detaching part 40 of the capsule housing/holding part 30 for cutting both axial ends of the capsule thereby perforating the capsule. A medicine capturing/collecting part 32 and a one-way valve 33 are built in a lower portion of the capsule housing/holding part 30, and a pump 50 having an air inlet valve 54 is built in the air flow inlet side thereof. A medicine delivery part 20 is built in the air exit of the capsule housing/holding part 30, a nozzle 22 is installed and medicine in the capsule can be dosed to the nasal cavities of the user by pressing the pump 50.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: March 3, 2015
    Assignee: Shin Nippon biomedical Laboratories, Ltd.
    Inventor: Tatsuo Tsutsui