Devices Placed Entirely Within Body And Means Used Therewith (e.g., Magnetic Implant Locator) Patents (Class 128/899)
  • Patent number: 11950997
    Abstract: An artificial cornea and an associated manufacturing method are disclosed. The artificial cornea has two sides, each of which has an associated microstructure. In an embodiment, microlines can be provided on an anterior side, and a posterior side can have micropores. Both the geometry of the microstructures and their dimensions can be customized for an individual patient. The geometry of the artificial cornea itself and its dimensions can also be customized as such. In addition, the lifetime of the artificial cornea can be significantly enhanced by adding co-polymer(s) into the hydrogel to strengthen its mechanical properties. Patient recovery can be aided by adding peptides into the artificial cornea surfaces to improve cell growth post-operation.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: April 9, 2024
    Assignee: The Trustees of the Stevens Institute of Technology
    Inventors: Yiwen Xi, Chang-Hwan Choi, Xiaojun Yu, Junfeng Liang
  • Patent number: 11918340
    Abstract: A medical system comprises a probe comprising a coil and a terminal distal end. The medical system further comprises a guide instrument comprising a terminal distal end, a sensor, and a lumen sized to receive the probe. The probe is configured to be inserted through the lumen to reach a worksite. At the worksite, the terminal distal end of the probe is configured to reach at least the terminal distal end of the guide instrument. The medical system further comprises processing hardware configured to receive a first signal from the coil and to receive a second signal from the sensor.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: March 5, 2024
    Assignee: Intuitive Surgical Opeartions, Inc.
    Inventor: Vincent Duindam
  • Patent number: 11832820
    Abstract: A positioning wand for assisting in positioning at least one of a first magnetic implant and a second magnetic implant configured for forming an anastomosis between two adjacent walls of a digestive tract of a patient is provided. The positioning wand can include an elongated member sized and configured to be inserted into an abdominal cavity of the patient, and a distal tip provided at a distal end of the elongated member. The distal tip can include a guide magnet configured to magnetically couple with the at least one of the first and second magnetic implants through a wall of the digestive tract to position the at least one of the first and second magnetic implants to a desired site of the anastomosis. The distal tip can be configured to be moveable in response to a contact pressure upon contact with the wall of the digestive tract.
    Type: Grant
    Filed: December 6, 2022
    Date of Patent: December 5, 2023
    Assignee: GT METABOLIC SOLUTIONS, INC.
    Inventors: Michel Gagner, Todd A. Krinke, Thierry Thaure
  • Patent number: 11819285
    Abstract: Electromagnetic navigation systems and methods detect ambient or extraneous magnetic interference by inhibiting the navigation system from generating an electromagnetic field and measuring, with a sensor, the strength of a magnetic field at one or more frequencies of and at one or more phases associated with the electromagnetic field generated by the navigation system. The systems and methods may further determine whether the strength of the magnetic field is greater than a threshold. Based on this determination, an alert or message may be generated.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: November 21, 2023
    Assignee: Covidien LP
    Inventors: Keith E. Jasperson, Michael R. Weisenberger, H. Aaron Christmann
  • Patent number: 11819320
    Abstract: The present invention discloses a method and system for determining orientation of a capsule endoscope. An external magnetic field is provided outside the capsule endoscope, and an internal magnetic field is provided inside the capsule endoscope. Magnetic field data is obtained according to the external magnetic field and the internal magnetic field, and acceleration data of the capsule endoscope is obtained. When the polarization direction of the external magnetic field is horizontal, the orientation information of the capsule endoscope is obtained according to the acceleration data. When the polarization direction of the external magnetic field is non-horizontal, the orientation information of the capsule endoscope is obtained according to the acceleration data and the magnetic field data.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: November 21, 2023
    Assignees: Ankon Medical Technologies (Shanghai) Co., LTD, ANX IP HOLDING PTE. LTD.
    Inventors: Xiaodong Duan, Qingqing Wang
  • Patent number: 11786232
    Abstract: A force-sensing joint tensioner assembly, surgical system, and method of use is provided. The joint tensioner assembly can include a housing that is configured to receive a fluid from a pump and a movable member that is configured to translate relative to the housing as the fluid is pumped into the housing. The tensioner and/or a surgical system including the tensioner can further include a pressure sensor configured to sense a pressure exerted by the movable member as the movable member translates and distracts the patient's joint. A surgical computer system can be configured to determine a distraction distance of the joint according to a volume of the fluid pumped into the joint tensioner assembly by the pump and/or determine a pressure exerted by the movable member according to the pressure sensor.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: October 17, 2023
    Assignees: Smith & Nephew, Inc., Smith & Nephew Orthopaedics AG, Smith & Nephew Asia Pacific Pte. Limited
    Inventor: Benjamin McCandless
  • Patent number: 11759189
    Abstract: A biodegradable scaffold for wound closure including a central rod and two spaced-apart plates. The central rod may have an engagement block on top for stabilizing an implanting tool. The two spaced-apart plates include an upper plate connected to the central rod and a lower plate connected to the central rod. Each of the upper and lower plates may include perforations which may be useful for detachably connecting an implanting tool and which encourage ingrowth of the tissue. The biodegradable scaffold allows tension free anatomic alignment of tissue within the plates and facilitates wound healing. The upper and lower plate may have a helical portion, in which each plate may extend around the central rod. The helical portion serves to draw or pull tissue around the wound defect into the scaffold in the course of deploying the scaffold.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: September 19, 2023
    Assignee: LAP IQ, INC.
    Inventors: Michael S. Klein, Michael G. Fourkas, James Su, Matias Bruzoni
  • Patent number: 11712546
    Abstract: Magnetic-based electronic valve readers for determining a location and orientation of magnets coupled to implantable medical devices to determine a setting of the device (e.g., setting of a fluid flow control valve of the medical device). The electronic valve readers include an orientation sensing mechanism that is provided and configured to enable the electronic valve reader to: 1) allow for internal offset calculation of an orientation change of the electronic valve reader during a reading process; and/or 2) during the reading process, provide an indication or warning to the clinician that the orientation of the electronic valve reader has changed to an extent at or exceeding a predetermined angular acceptance threshold or window. Systems including the disclosed electronic valve readers and methods of reading a setting of the device are also disclosed.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: August 1, 2023
    Assignee: Medtronic Xomed, Inc.
    Inventor: Drew Amery
  • Patent number: 11712171
    Abstract: A location of a number of fiducial points can be computed. The fiducial points can include impedance locations of an electrode disposed on a catheter in an impedance based coordinate system and magnetic locations of a magnetic position sensor disposed on the catheter in a magnetic based coordinate system. The impedance location of the electrode in the impedance based coordinate system can be transformed into a transformed impedance location of the electrode in the magnetic based coordinate system. A magnetic location of the electrode in the magnetic based coordinate system can be determined. A determination of whether an impedance shift exists between the transformed impedance location of the electrode in the magnetic based system and the magnetic location of the electrode in the magnetic based system can be made. An electromagnetic dynamic registration can be generated between the impedance based coordinate system and the magnetic based coordinate system based on the impedance shift.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: August 1, 2023
    Assignee: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventors: Yuriy Malinin, Anthony D. Hill, Cable P. Thompson, Linda Ruetz
  • Patent number: 11684285
    Abstract: A location of a number of fiducial points can be computed. The fiducial points can include impedance locations of an electrode disposed on a catheter in an impedance based coordinate system and magnetic locations of a magnetic position sensor disposed on the catheter in a magnetic based coordinate system. The impedance location of the electrode in the impedance based coordinate system can be transformed into a transformed impedance location of the electrode in the magnetic based coordinate system. A magnetic location of the electrode in the magnetic based coordinate system can be determined. A determination of whether an impedance shift exists between the transformed impedance location of the electrode in the magnetic based system and the magnetic location of the electrode in the magnetic based system can be made. An electromagnetic dynamic registration can be generated between the impedance based coordinate system and the magnetic based coordinate system based on the impedance shift.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: June 27, 2023
    Assignee: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventors: Yuriy Malinin, Anthony D. Hill, Cable P. Thompson, Linda Ruetz
  • Patent number: 11678886
    Abstract: Methods and devices for treating a cerebral aneurysm utilize a device that includes a self-expanding resilient permeable shell made from elongate resilient filaments. At least some of the filaments have a distal region that extends beyond the distal end of the permeable shell and form an extension having a generally circular shape when expanded. The permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded state with a globular, axially shortened configuration. The permeable shell has a plurality of openings formed between the braided filaments. The distal regions of the plurality of filaments that form the extension may be braided, partially braided, or unraveled. Once deployed within the cerebral aneurysm, the extension may be positioned near a dome of the cerebral aneurysm.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: June 20, 2023
    Assignee: MICROVENTION, INC.
    Inventors: Todd Hewitt, Brian E. Merritt, William R. Patterson, James M. Thompson, Claudio Plaza, Hung P. Tran
  • Patent number: 11654037
    Abstract: A vascular remodeling device has a plurality of sections, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. Each section has a plurality of interconnected struts that define a waist, a proximal face, and a distal face. Each face comprises (i) a plurality of distal strut portions extending proximally from a distal side of the face, (ii) a plurality of proximal strut portions extending distally from a proximal side of the face, and (iii) a plurality of sub-struts, wherein, from each proximal strut portion, two of the sub-struts each extend to a different one of the distal strut portions.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: May 23, 2023
    Assignee: COVIDIEN LP
    Inventors: Masoud Molaei, Evan Epstein, Gabriel Newell, Quang Tran
  • Patent number: 11624937
    Abstract: A contact lens configured to decrease dark adaptation comprises one or more LEDs and directs light from the LED away from the fovea and toward the parafovea or perifoveal regions of the retain. In some embodiments, soft contact lens embedded with one or more arrays of microLEDs and electronics operating the LEDs is configured to be worn at night in order to inhibit dark adaptation and reduce oxygen consumption by the rods. The contact lens may be made of a single layer of a contact lens material or multiple layers sandwiching a flexible transparent plastic layer comprising the electronics and the LED arrays. The contact lens may be made of a hydrophilic hydrogel material that is biocompatible to the human cornea, or a silicone hydrogel material. The contact lens may be spherical and may provide refractive correction to the eye of the wearer.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: April 11, 2023
    Assignee: ACUCELA INC.
    Inventors: Amitava Gupta, Ryo Kubota
  • Patent number: 11622775
    Abstract: Pulmonary artery banding device includes an inflating handing ring, to be installed around the patient's pulmonary artery, an extending tube, and an insufflating button, the extending tube connecting insufflating button to the banding inflating ring, the banding ring being configured as a C-shape hydraulic sleeve forming a support for an inflating balloon, whose external wall is formed by a thin rigid silicon layer, and whose inside wall is formed by a thin flexible silicon layer, at the apart ends of the banding ring two brims being disposed to facilitate the size banding adjustment according with the pulmonary artery caliber. The banding ring is provided with holes for passage of sutures fixating the ring on the pulmonary artery of the patient; the insufflating button being configured as a cylindrical reservoir and being provided with holes for sutures. Also a method of using the banding ring for performing a medical procedure on a patient who is an infant or neonate.
    Type: Grant
    Filed: December 29, 2018
    Date of Patent: April 11, 2023
    Inventor: Renato Sammy Assad
  • Patent number: 11612308
    Abstract: A control method, a control system, an electronic device and a readable storage medium for a capsule endoscope are disclosed. The method comprises: obtaining the initial distance H between the capsule endoscope and an external magnetic field generating device based on magnetic field information when the capsule endoscope is positioned in the vertical direction of the magnetic field generating device in an initial state; presetting a target area according to the force balance of the in vivo capsule endoscope, and adjusting the distance between a second permanent magnet and the capsule endoscope to locate the capsule endoscope in the target area; monitoring the acceleration of the capsule endoscope, and determining the vertical component of acceleration of the capsule endoscope; and adjusting the current of the electromagnetic induction coil according to the vertical component of the acceleration to finely adjust the force balance of the capsule endoscope in the target area.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: March 28, 2023
    Assignee: ANKON TECHNOLOGIES CO., LTD
    Inventors: Tianyi Yangdai, Hao Liu, Xinhong Wang
  • Patent number: 11612437
    Abstract: A location pad includes multiple field-generators, a frame and a mounting fixture. The multiple field-generators are configured to generate respective magnetic fields in a region-of-interest of a patient body, for measuring a position of a medical instrument in the region-of-interest. The frame is configured to fix the multiple field-generators at respective positions surrounding the region-of-interest. The mounting fixture is configured to position the frame above the patient body.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: March 28, 2023
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Assaf Govari, Vadim Gliner
  • Patent number: 11589779
    Abstract: Systems, methods, and devices relating to a sensor array for use with a user's finger segment and which indirectly maps the topography of a surface under the finger segment. Each sensor array is worn on a user's finger segment and has multiple sensitive strain gauges as well a positioning sensor. The multiple strain gauges are deployed around the periphery or sides of the finger segment. Each strain gauge measures the deformation of the finger segment pad as the finger segment passes over the surface topography. The relative ratios of the deformation detected indicates the location of a feature or contact point on the topography relative to the group of strain gauges. The positioning sensor determines the array's orientation as well as its location relative to a predetermined global reference frame.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: February 28, 2023
    Inventors: Louis Ferreira, Ryan Kope
  • Patent number: 11590321
    Abstract: A steerable guide catheter includes a tip ring at a distal end and one or more pullwires configured to engage with the tip ring when put in tension, the pullwire(s) thereby subjecting the steerable guide catheter to a curving or turning force. The tip ring includes a saddle and one or more pullwire channels allowing the pullwire to be looped over the saddle such that when the pullwire is placed under tension, it abuts against the saddle of the tip ring. Some embodiments include additional catheters axially aligned within or outside of the steerable guide catheter, and include a keying feature aligning the rotation of the multiple catheters. The keys of the keying feature can be formed of a polyamide with a glass microsphere filler, and can be thermally welded to the catheter.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: February 28, 2023
    Assignee: EVALVE, INC.
    Inventors: Dylan T. Van Hoven, Jose C. Vital, Amy Lee
  • Patent number: 11590685
    Abstract: A fiber aggregation contains fiber containing a thermoplastic resin, each of the fiber being mutually joined and aligned.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: February 28, 2023
    Assignee: RICOH COMPANY, LTD.
    Inventors: Sohichiroh Iida, Hitoshi Iwatsuki, Mitsuru Naruse, Satoshi Ogawa, Yunsheng Sun
  • Patent number: 11571198
    Abstract: An intravascular delivery device is disclosed comprising a delivery wire having a proximal and a distal end and an interior lumen extending there between and wherein said distal end comprises a connection interface adapted to matingly interlock with a proximal end portion of a medical implantable device, wherein said delivery device comprises a locking unit arranged to secure said connection interface in a locking position in which said medical implant is pivotably locked before a controlled release.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: February 7, 2023
    Assignees: Maslanka Patentverwaltung GmbH, Occlutech Holding AG
    Inventors: Herbert Maslanka, Stevan Nielsen
  • Patent number: 11553937
    Abstract: A medical tool includes, a deflectable distal end, at least a pull wire, and a deflection assembly. The at least pull wire having a first end coupled to the distal end of the medical tool and configured to be moved for deflecting the distal end. The deflection assembly is coupled to a second end of at least the pull wire and is configured to control a deflection of the distal end. The deflection assembly includes a first gear having a first rotation axis, and a second gear, having a second rotation axis and including a jagged surface for integrating with the first gear. The jagged surface is slanted relative to the second rotation axis, and when the first gear rotates, the second gear is configured to be rotated by the first gear, to move along the second rotation axis and to deflect the distal end by moving the pull wire.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: January 17, 2023
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Yehuda Algawi, Assaf Govari, Ilya Sitnitsky, Stanislav Katzir
  • Patent number: 11553941
    Abstract: A self-closing device for implantation within a patient's body includes base material including an inner surface area for securing the base material to a tissue structure, and a plurality of support elements surrounding or embedded in the base material. The support elements are separable to accommodate creating an opening through the base material for receiving one or more instruments through the base material, and biased to return towards a relaxed state for self-closing the opening after removing the one or more instruments. The device may be provided as a patch, cuff, or integrally attached to a tubular graft or in various shapes.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: January 17, 2023
    Assignee: Solina Medical Inc.
    Inventors: James Hong, Amy Lee, Erik van der Burg
  • Patent number: 11553831
    Abstract: A surgical tool, consisting of a handle and a flexible insertion tube, having a proximal end coupled to the handle and a distal end configured to be inserted into an orifice of a living subject. The tool has an inner tube, which is bendable without breaking over a range of angles in response to a bending force, and which retains the bent shape after the bending force has been removed. The inner tube is located within the insertion tube. A flexible tubing defines a lumen and is contained within the inner tube. A tool working tip is configured to contact tissue in the subject and to mate with a distal termination of the inner tube. A rigid outer tube grips outer surfaces of the working tip and of the inner tube so as to maintain an opening of the working tip in communication with the flexible tubing lumen.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: January 17, 2023
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Christopher Thomas Beeckler, Kevin Mark Okarski, Assaf Govari, Vadim Gliner
  • Patent number: 11541895
    Abstract: A driving assistance system and a driving assistance method are provided. The driving assistance system includes a physiological information sensing system, an external physical symptom detection system, and a processing device. The physiological information sensing system is configured to sense physiological information of a driver. The external physical symptom detection system is configured to detect an external physical symptom of the driver. The processing device is coupled to the physiological information sensing system and the external physical symptom detection system. When the physiological information of the driver and the external physical symptom of the driver are abnormal, the processing device initiates an emergency procedure.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: January 3, 2023
    Assignee: Industrial Technology Research Institute
    Inventors: Ming-Huan Yang, Kuang-Ching Fan, Cheng-Chung Lee
  • Patent number: 11534171
    Abstract: A positioning wand for assisting in positioning at least one of a first magnetic implant and a second magnetic implant configured for forming an anastomosis between two adjacent walls of a digestive tract of a patient is provided. The positioning wand can include an elongated member sized and configured to be inserted into an abdominal cavity of the patient, and a distal tip provided at a distal end of the elongated member. The distal tip can include a guide magnet configured to magnetically couple with the at least one of the first and second magnetic implants through a wall of the digestive tract to position the at least one of the first and second magnetic implants to a desired site of the anastomosis. The distal tip can be configured to be moveable in response to a contact pressure upon contact with the wall of the digestive tract.
    Type: Grant
    Filed: November 11, 2021
    Date of Patent: December 27, 2022
    Assignee: GT METABOLIC SOLUTIONS, INC.
    Inventors: Michel Gagner, Todd A. Krinke, Thierry Thaure
  • Patent number: 11523732
    Abstract: A compliant surgical device such as a flexible entry guide employs tendons to operate or steer the device and attaches asymmetric or constant force spring systems to control tension in the tendons. As a result, the surgical device can be compliant and respond to external forces during a surgical procedure without rapidly springing back or otherwise causing a reaction that damages tissue. The compliance also permits manual positioning or shaping of the device during or before insertion for a surgical procedure without damaging the tendons or connections of the tendons within the device or to a backend mechanism.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: December 13, 2022
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: Giuseppe M. Prisco, Eugene F. Duval, Theodore W. Rogers
  • Patent number: 11510770
    Abstract: An obesity treatment apparatus comprises at least one operable stretching device (10) implantable in an obese patient and adapted to stretch a portion (12a) of the patient's stomach wall (12), and an operation device (16, 18) for operating the stretching device when implanted to stretch the stomach wall portion such that satiety is created.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: November 29, 2022
    Inventor: Peter Forsell
  • Patent number: 11452464
    Abstract: Systems and methods for guided endoscope navigation include a registration module (118) configured to, using a processor, register a first set of images (112) with a second set of images (114) of an endoscope (102). A selection module (120) is configured to receive selected areas of interest on the first set of images and transform the selected areas of interest to an endoscope coordinate frame. A guidance module (122) is configured to overlay guidance tools onto the second set of images to permit a user of the endoscope to navigate to the selected areas of interest.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: September 27, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Aleksandra Popovic, Haytham Elhawary
  • Patent number: 11439492
    Abstract: The invention provides a filter assembly including a string or wire such that a lasso type cincture is effected, said filter being openable and closeable while in deployed within a bodily vessel. A string lengthen or shorting adjustment mechanism, such as a ratchet or reel allows more length of string into the device or alternatively to shorten the length of available string in the system. The described invention, when used to ameliorate venous clots and most arterio-venous dialysis grafts, a filter-tipped aspirator is used downstream from the clot to capture and remove dislocated emboli. A method of using same is disclosed.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: September 13, 2022
    Inventor: Daniel Ezra Walzman
  • Patent number: 11422208
    Abstract: A magnetic sensor includes a magneto-sensitive portion (105); an excitation wiring (110) formed in a wiring region above the magneto-sensitive portion (105) through intermediation of an insulating film (12), the excitation wiring (110) including a plurality of conductor portions (1101, 1102, 1103, 1104, and 1105) arranged in in order across at least one radial direction from a center axis of the magneto-sensitive portion (105); a current flowing through the excitation wiring (110) having a current density of which an absolute value becomes zero in a vicinity of a center of the magneto-sensitive portion (105) and continuously increases toward an outer side of the magneto-sensitive portion (105); and a magnetic field generated by the current flowing through the excitation wiring (110) in a direction vertical to the surface of the magneto-sensitive portion (105).
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: August 23, 2022
    Assignee: ABLIC INC.
    Inventor: Hirotaka Uemura
  • Patent number: 11413047
    Abstract: An occlusive medical implant having a frame actuatable between a collapsed delivery configuration and an expanded implanted configuration, the frame including a generally tubular portion with a threaded insert configured to removably attach to a threaded distal end of a core wire; an occlusive element disposed on the frame; where a proximal portion of the occlusive element and the proximalmost extent of the threaded insert are substantially coplanar with a plane defined by three or more proximalmost extents of the frame in the expanded implanted configuration.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: August 16, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Christopher J. Clark, Mark McPhail, Brian J. Tischler, Dennis A. Peiffer, Burns P. Doran
  • Patent number: 11406461
    Abstract: A delivery system and methods are disclosed for delivering a material to a target site. A delivery instrument is coupled to a robotic manipulator and comprises a delivery device having a distal tip comprising an opening deliver the material to the target site through the opening. A navigation system tracks the delivery device and the target site and generates position signals. One or more controllers are in communication with the robotic manipulator and the navigation system and define a virtual boundary associated with the target site, wherein the virtual boundary is utilized to constrain movement of the delivery device. The one or more controllers control one or more joint motors of the robotic manipulator to move the distal tip of the delivery device with respect to the virtual boundary based on the position signals from the navigation system.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: August 9, 2022
    Assignee: Stryker Corporation
    Inventors: John J. Janik, Robert A. Brindley
  • Patent number: 11395887
    Abstract: A device for delivering a compound to the olfactory region of the nasal cavity includes an actuator body and a tip that removably couples to the actuator body. The actuator body includes a propellant channel in fluid communication with a propellant canister. The tip includes an exit channel, an inlet interface, one or more grooves, and an outlet orifice. The exit channel extends between a proximal end and a distal end of the tip. The inlet interface is positioned about a distal end of the exit channel, and the inlet interface couples to a compound container containing the compound. The grooves are positioned about the inlet interface and direct propellant from the propellant channel into the compound container, thereby agitating and entraining the compound in the compound container with the released propellant. The compound and the propellant then travel through the exit channel and out the outlet orifice.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: July 26, 2022
    Assignee: Impel Pharmaceuticals Inc.
    Inventors: Craig Frederick Kohring, Christopher William Fuller
  • Patent number: 11382714
    Abstract: An ultrasound-detectable marker, ultrasound system, and methods for monitoring vascular flow and patency are disclosed. The ultrasound-detectable marker comprises one or more resorbable polymers, one or more non-resorbable polymers, one or more non-polymeric materials, or any combinations thereof. The ultrasound-detectable marker is adapted for placement underneath, adjacent to, or above one or more vessels at a postoperative site, such as a vascular anastomosis site. Further, the ultrasound imaging system includes certain user guiding software and/or health analysis software for use with the ultrasound-detectable marker.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: July 12, 2022
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Devin O'Brien-Coon, Kaitlyn Harfmann, Ting Yu Lai, David Narrow, Adam Lightman, Youseph Yazdi
  • Patent number: 11382709
    Abstract: A tissue expander is disclosed herein. The tissue expander may comprise a shell defining a chamber, and having a flexible wall and a port disposed through the flexible wall. The shell may also include a channel disposed through the flexible wall. A first syringe containing a first volume of a liquid may be connected to the chamber of the tissue expander via the channel. A second syringe containing a second volume of the liquid may be connected to the chamber via the port at least approximately one week after the first volume of liquid is injected. The first volume of liquid may be injected more quickly than the second volume of liquid.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: July 12, 2022
    Assignee: MENTOR WORLDWIDE LLC
    Inventors: Gordon Lamar Kirchhevel, David Henry Taffe
  • Patent number: 11344382
    Abstract: Provided herein are systems and methods comprising localization agents. For example, provided herein are systems and methods for the placement of localization devices within biological systems and the detection of such localization devices for targeted surgeries or other medical procedures. For example, provided herein are systems comprising one or more miniature detectable devices that are placed into a target location and activated by remote introduction of a magnetic field.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: May 31, 2022
    Assignee: ELUCENT MEDICAL, INC.
    Inventors: Laura G King, Daniel W. Van Der Weide, Fred T. Lee, Jr.
  • Patent number: 11345882
    Abstract: An extra-capillary fluid cycling unit for maintaining and cycling fluid volumes in a cell culture chamber includes a housing and a first flexible reservoir extra-capillary fluid reservoir disposed in the housing. The extra-capillary fluid reservoir is in fluid communication with a cell culture chamber. A second flexible reservoir is also located in the housing, the second flexible reservoir being in fluid communication with a pressure source. A sensor plate is movably disposed in the housing between the extra-capillary reservoir and the second reservoir, wherein the second reservoir is pressurized to move the sensor plate in relation to the extra-capillary reservoir to cause fluid cycling and maintain fluid volumes in the cell growth chamber.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: May 31, 2022
    Assignee: BIOVEST INTERNATIONAL, INC.
    Inventors: Darrell Paul Page, Robert J. Wojciechowski, Martin Peder Crep
  • Patent number: 11337684
    Abstract: An occluder has a first disk-shaped structure with a grid, wherein the first disk-shaped structure is woven from at least two groups of braided wires, and the two groups of braided wires are crossed to form multiple rings of crossing points. A blocking membrane is also arranged in the disk-shaped structure, with an edge of the blocking membrane connected to the outermost ring of crossing points of the multiple rings of crossing points through a sewing wire, and the number of crossing points in the outermost ring of crossing points sewn with the blocking membrane is smaller than the number of all the crossing points in the outermost ring of the crossing points. The occluder can reduce the possibility of the phenomenon where the edge of the blocking membrane cannot abut against a disk face edge of the occluder, thereby improving the occlusion effect of the occluder.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: May 24, 2022
    Assignee: Lifetech Scientific (Shenzhen) Co. Ltd.
    Inventors: Jie Zhang, Xianmiao Chen, Yueying Deng, Wenfeng Li
  • Patent number: 11331000
    Abstract: A method of operating a localization array. The method includes providing the localization array in substantially an optimal position. The method also includes maintaining the localization array at substantially the optimal position by controlling movement of the localization array.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: May 17, 2022
    Assignee: ACCURAY INCORPORATED
    Inventors: Adam Jerome Weber, Eric Earnst, Calvin R. Maurer, Jr., Gopinath Kuduvalli, Christopher A. Raanes
  • Patent number: 11317823
    Abstract: An example system includes a distortion reference sensor (DRS) device attachable to a surface adjacent a region of interest within the patient. The DRS device includes at least two sensor coils arranged at a predetermined angle relative to each other and at a predetermined spatial position in a three-dimensional space relative to each other. The system also includes a computing device to determine a sensed angle and a sensed spatial position of the at least two sensor coils in the three-dimensional coordinate system in response to application of an electromagnetic field. Electromagnetic field distortion is indicated based on a difference between the predetermined angle and the sensed angle and/or the predetermined spatial position and the sensed spatial position exceeding an expected difference value.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: May 3, 2022
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Jeffrey H. Yanof, Karl West
  • Patent number: 11317987
    Abstract: Tissue localization devices and methods of localizing tissue using tissue localization devices are disclosed. The tissue localization device can comprise a handle comprising a delivery control, a delivery needle extending out from the handle, and a localization element within the delivery needle. The localization element can be deployed out of the delivery needle or retracted back into the delivery needle when the delivery control is translated in a first direction or a second direction, respectively. The localization element can be coupled to a flexible tracking wire.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: May 3, 2022
    Assignee: HOLOGIC, INC.
    Inventors: George D. Hermann, Jonathan M. Olson, Michael J. Drews, Gail S. Lebovic, David B. Willis
  • Patent number: 11317967
    Abstract: Magnetic guided ablation catheters and methods of manufacture are disclosed. In an exemplary embodiment, a catheter includes a unitary flexible tubing having a proximal end and a distal end. A plurality of magnets are positioned along an axis of the unitary flexible tubing, the plurality of magnets provided within the unitary flexible tubing. During operation, the plurality of magnets are responsive to an external magnetic field to selectively position and guide the catheter within a body of a patient.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: May 3, 2022
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Kirk Kochin Wu, Yongxing Zhang
  • Patent number: 11317988
    Abstract: A system for locating an implanted device including magnetic coils within a subject is provided. The system includes a magnetic sensor array including a plurality of magnetic sensors, the magnetic sensor array configured to measure a magnetic field generated by the implanted device, and a position detection module communicatively coupled to the magnetic sensor array, the position detection module configured to receive the measured magnetic field from the magnetic sensor array, and calculate a position of the implanted device based on the measured magnetic field.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: May 3, 2022
    Assignee: TC1 LLC
    Inventors: John Freddy Hansen, Christopher Eskildsen
  • Patent number: 11260211
    Abstract: A variable volume infusion port is provided. The infusion port may include a port body having an internal fluid reservoir, a septum, a stem to fluidly couple to a catheter lumen, and a displaceable member disposed in the internal fluid reservoir. In a first position, the displaceable member is disposed proximate the septum, providing a relatively small fluid volume within the infusion port. Insertion of an injection device through the septum causes the displaceable member to move to a second location distal from the septum, providing a relatively large fluid volume within the infusion port for the duration the injection device remains in the infusion port. The displaceable member may include a rigid member operably coupled to a biasing element or a flexible member coupled to a biasing element.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: March 1, 2022
    Assignee: PRIMO MEDICAL GROUP, INC.
    Inventor: Richard P. Rodgers
  • Patent number: 11253657
    Abstract: Embodiments of the invention provide devices, systems, and methods that precisely identify a minimum of one predetermined spot which is hidden under a skin. The system comprises a locator device and corresponding implanted target device. The port locator device preferably comprises one magnet with north and south magnetic pole, a body and a suspending component. The body may utilize specific geometry which improves accuracy. The implanted target device may include at least one magnet and at least one target or a plurality of targets and at least one magnet. Various configurations can be provided that precisely identify a single spot or a plurality of spots which are hidden under a skin.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: February 22, 2022
    Assignee: SIENTRA, INC.
    Inventor: Steven Charles Geiger
  • Patent number: 11253167
    Abstract: Systems and methods for detecting metal clips inserted within a portion of a body of a patient are disclosed herein. In one embodiment, a clip detector assembly includes a detector having a ferrous member, a transmitting coil around the ferrous member and configured to induce a current in the metal clip, and a receiving coil around the ferrous member and configured to receive a magnetic field generated by the current induced in the metal clip. The assembly can further include a control circuit having a band-pass filter configured to pass electrical signals induced by the magnetic field from the receiving coil that are within at most 35 kHz of a resonance frequency of the metal clip. The assembly still further includes a user notification component configured to alert a user to a location of the metal clip.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: February 22, 2022
    Assignees: MUSC Foundation for Research Development, Clemson University Research Foundation
    Inventors: Nancy DeMore, Delphine Dean, Scott R. Slaney, Melissa McCullough, Cody Jordan, Joseph R. Wilson, III
  • Patent number: 11253166
    Abstract: This invention relates to a method of catheter and radiating coil location in a human body. In particular, when a radiating coil is used in conjunction with a catheter, a coil locating device can be used to determine the distance the coil is from the device and its depth in the patient's body. A display is provided that shows both a reference image of a portion of a non-subject body and an image of the coil located on the display with reference to the reference image. This is achieved by locating the coil-locating device on a predetermined landmark on the patient's body. The coil and its signal wires can be incorporated into a stylet, guide wire or a catheter. The coil locating device can be orientated towards the head of the patient and for an axis of the device to be aligned with the mid sagittal plane of the patient.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: February 22, 2022
    Assignee: Avent, Inc.
    Inventors: William John Besz, Donald Philip Chorley, Stuart Brasted, Robert Anthony Walker
  • Patent number: 11234769
    Abstract: A medical system tracks the position of a portion of a medical instrument within a body of a patient. In some embodiments, the medical instrument includes a needle, a syringe, and a needle-position-tracking element positioned between the needle and the syringe and in fluid communication with both. The needle-position-tracking element includes an electromagnet structure that includes a core, a conductive coil wrapped around the core, and ancillary circuitry configured to pass a current through the conductive coil to thereby generate a magnetic field. A sensor device senses the magnetic field and generates corresponding sensor signals. A control circuit calculates the position of a portion of the medical instrument based on the sensor signals.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: February 1, 2022
    Assignee: Lucent Medical Systems, Inc.
    Inventors: Curtis S. King, Steve Vincent, Samuel Peter Andreason
  • Patent number: 11229440
    Abstract: Expandable occlusive plugs and methods of using them are disclosed. The devices generally include an expandable framework at least partially covered by a membrane. The occlusive plugs can be used for occlusion of body lumens and/or to limit migration of embolic agents to non-target sites.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: January 25, 2022
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Robert Squire, Joel Munsinger, Derek Larson, Martin Willard, Joseph Connolly
  • Patent number: 11224484
    Abstract: Surgical systems for use in surgical procedures utilizing robotic devices. The surgical system having one or more components for housing a sensor or one or more tools for anchor or sensor delivery. The surgical system may include a surgical sensor anchor and/or a surgical sensor anchor delivery tool. A method of performing a robotically assisted surgical procedure, comprising using a surgical sensor anchor during a surgical procedure which utilizes a robot to track movement of at least one portion of a body structure undergoing a surgical procedure or to track movement of a body structure near a surgical site.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: January 18, 2022
    Assignee: Globus Medical Inc.
    Inventors: Peter L. Bono, James D. Lark, John S. Scales, Thomas J. Lord