Abstract: Described is a device for measuring fluid density. The device is a flow meter including a housing with one side configured to mount to a flow conduit and define an outlet flow orifice near one end of the housing. The other side defines an inlet flow orifice near another end of the housing. The housing permits fluid to be introduced into the inlet flow orifice, flow through a flow cavity, and pass from the outlet flow orifice. The flow meter also includes a sensor head near the outlet flow orifice. The sensor head vibrates at a frequency upon introduction of electrical power while in contact with a fluid, detects the vibration frequency of the sensor head, and transmits the detected vibration frequency, which is associated with a density of the fluid. A system and method for determining a fluid density of a fluid using the described device is also disclosed.

Abstract: A method for analyzing a target nucleic acid includes diluting nucleic acid targets and filling pico to femto-liter sized wells such that they contain a single target nucleic acid and one or more amplification reagents, amplifying the target in the individual wells, distinguishing wells containing amplicon from the target and amplicon from a variant of the target generated by polymerase error by using two differently labeled-hybridization probes, one hybridizing to the target and one hybridizing to a specific variant of the target; and analyzing target amplicons.

Abstract: A device and method for detecting the presence of bacteria in a sample are provided. A multi-step process for sample preparation is utilized and a microfluidic device is disclosed. The detection is performed using microfluidics and physical changes in multiple samples in differential mode.

Abstract: A sensor device is for detecting metal. The sensor device may have a substrate, an electrode on the substrate, and a biopolymer-metal composite film on the electrode. The biopolymer-metal composite film may include a metal and a biopolymer. The sensor device may further have circuitry coupled to the electrode and configured to apply a sensing signal to the electrode.

Abstract: The application relates to an assembly for controlling detonation wave mode of a rotating detonation combustion chamber, which includes an inner barrel, an outer plate and at least one sectoral direction-changing block. The outer plate is sleeved outside the inner barrel. An annular cavity is formed between the outer plate and the inner barrel. At least one groove is arranged on one side of the outer plate close to the inner barrel. The groove wall comprises an arc edge and a straight edge. The groove is connected with the annular cavity. The sectoral direction-changing blocks are arranged in the grooves in one-to-one correspondence. An arc edge of the sectoral direction-changing block is positioned far away from the inner barrel.

Abstract: An apparatus comprises a mounting panel including a top plate having multiple vias and multiple orifices. An internal face of the top plate includes a first cut-out region and channels through which to flow a process fluid. The first cut-out region can be a reservoir in which to contain the process fluid. The multiple vias are adapted for passing the process fluid through the top plate. The multiple orifices are adapted for attaching a plurality of process fluid control components to the mounting panel. An inner plate also has multiple additional vias. The apparatus includes a bottom plate, where the inner plate is compacted between the top plate and the bottom plate to form an integral metallic body in which to contain and flow the process fluid.

Abstract: A method of manufacturing a microfluidic system or microfluidic device having at least one channel includes providing a base sheet, providing a deformable intermediate layer, providing a cover film, and laminating the base sheet, the intermediate layer and the cover film so that a back surface of the intermediate layer is attached to a front surface of the base sheet and a back surface of the cover film is attached to a front surface of the intermediate layer opposite to the back surface thereof, thereby forming a laminate comprising the base sheet, the intermediate layer and the cover film. Further, the method includes applying pressure to the front surface of the intermediate layer through the cover film so as to deform the intermediate layer, thereby forming the at least one channel. The invention also relates to a microfluidic system or microfluidic device) manufactured by this method.

Abstract: An aerosol-generating system is provided, including a medicament source and a volatile delivery enhancing compound source. The volatile delivery enhancing compound source includes a first sorption element, a second sorption element downstream of the first sorption element, and a volatile delivery enhancing compound sorbed on the first sorption element and the second sorption element, wherein a rate of release of the volatile delivery enhancing compound from the first sorption element is greater than a rate of release of the volatile delivery enhancing compound from the second sorption element.

Abstract: A valve (10) includes a first case member (101) having an inflow port (H1) and a first valve seat (VS), a second case member (105) having an air outlet (H2) and a discharge port (H3), a valve chamber formed by bonding the first case member (101) and the second case member (105), at least one of which has a recessed shape, with a first bonding member (300) while the recessed shape is located on an inner side, and a diaphragm (150) formed so as to partition the valve chamber into a lower valve chamber (106) connected to the inflow port (H1) and an upper valve chamber (107) connecting the discharge port (H3) and the air outlet (H2).

Abstract: A microfluidic system includes a substrate, a set of input ports coupled to the substrate, and a set of output ports coupled to the substrate. The microfluidic system also includes a microfluidic processing system coupled to the substrate and including a plurality of processing sites. The microfluidic processing system is coupled to the set of input ports and the set of output ports. The microfluidic system further includes one or more microfluidic logic devices coupled to the substrate and operable to control at least a portion of the microfluidic processing system.

Abstract: An embodiment is a scientific fluidic device and a method of assembly of single and multilayer fluidic devices via laser cut and assembly of double sided adhesives. The device includes a member defining a cavity and having two sides, both sides including an adhesive compound, and at least one substrate defining at least two plenums and coupling to the member, forming a flow path. The components of the fluidic device are produced via laser cut and assembly methods. The fluidic device remains intact via adhesive coupling between the substrate(s), member(s), and membrane(s). Altogether, the fluidic device requires assembly that is efficient and economical, resulting in high throughput manufacturing of the fluidic devices.

Abstract: A modular microfluidic system includes a first microfluidic module and a second microfluidic module. The first microfluidic module has a first module body including a microfluidic channel and a first connector extending outward from the module body. The first connector is provided with a protrusion. The second microfluidic module has a second module body including a microfluidic channel, a second connector including a guider configured to guide the protrusion upon insertion of the first connector into the second module body, and a locker configured to fix the protrusion. Upon fluidly coupling the first microfluidic module and the second microfluidic module, an O-ring is disposed between the first connector and the second connector.

Abstract: A manually actuated chromatography device comprising a chamber for receiving a liquid sample, a pump with a metering valve, and a chromatography element, wherein the pump moves a predetermined volume of liquid from the sample chamber to the chromatography element.

Abstract: The present invention generally relates to multi-layer, flat glass structures and a method of manufacturing multi-layer, flat glass structures.

Abstract: Disclosed is a method of preparing a flexible deformable photonic crystal material for structural health monitoring, comprising the following steps: washing a grating master template; preparing and assembling a mold; obtaining an assembled mold by printing a three-dimensional mold comprising an upper die and a lower die by use of a 3D printing device and installing the grating master template on the three-dimensional mold; obtaining a polydimethylsiloxane (PDMS) one-dimensional photonic crystal film by replicating a one-dimensional grating structure of a surface of the grating master template by pouring PDMS into the assembled mold; finally, obtaining the PDMS one-dimensional photonic crystal film with a one-dimensional photonic crystal structure on a middle surface and protrusion structures at both ends by demolding, wherein the PDMS one-dimensional photonic crystal film is the flexible deformable photonic crystal material.

Abstract: An active separation control system, comprising a fluidic oscillatory actuator having an ejector member, an oscillator member, and a joining channel between said oscillator member and said ejector member, all mounted on at least one flexible member, said fluidic oscillatory actuator being mountable on a rotatable door of a vehicle such that said flexible member assumes a different shape when said door is closed than when said door is open, wherein said joining channel is also flexible to assume a shape of said flexible member.

Abstract: A liquid cooling module comprises a cooling plate, including a plurality of cooling channels for liquid flowing, and a pump block, integrated with the cooling plate and including a pump and a heat exchange chamber connecting to the plurality of cooling channels of the cooling plate, to form a circulation loop.

Abstract: A fluid monitoring module includes a flow sensing device and a controller disposed in an enclosure. The flow sensing device includes a body including an inlet port, an outlet port, an upstream sensor port, a downstream sensor port, and a flow passage disposed between the inlet port and the outlet port, and between the upstream sensor port and the downstream sensor port. A first fluid sensor is assembled with the upstream sensor port, and a second fluid sensor is assembled with the downstream sensor port. The controller is in circuit communication with the first and second fluid sensors for receiving at least one of pressure indicating signals and temperature indicating signals from each of the first and second fluid sensors, and for measuring fluid data based on the received signals.

Abstract: A method for forming a surface enhanced Raman spectroscopy (SERS) sensing apparatus may include providing a body having an internal microfluidic passage, the microfluidic passage having an interior surrounded by an interior surface, depositing a conformal inorganic passivation film onto the interior surface so as to continuously surround the interior by atomic layer deposition and positioning a SERS sensor in connection with the microfluidic passage after the depositing of the conformal inorganic film.

Abstract: A microfluidic probe includes a probe head with a processing surface that includes a first aperture and a second aperture. The probe further includes a liquid injection channel, which leads to the first aperture, and a liquid aspiration channel, which extends from the second aperture. The probe also includes a bypass channel, arranged so as to fluidly connect the liquid injection channel to the liquid aspiration channel, as well as a control channel. The latter fluidly connects to the bypass channel, hence forming a junction therewith, so as to define two portions of the bypass channel. These portions includes: a first portion that extends from the junction to the liquid injection channel; and a second portion that extends from that same junction to the liquid aspiration channel. The invention is further directed to methods of operation of a probe as described above, to process a surface.

Abstract: The present disclosure is directed to the creation and/or manipulation of microfluidic systems and methods that can be formed in pre-existing modular blocks. Microfluidic paths can be formed in one or more blocks, and when multiple blocks are used, the blocks can be used together to form a path across the blocks. The paths can be sealed to prevent fluid leakage. The modular blocks can be readily available blocks which can then be individually customized to achieve various microfluidic design goals. The paths can be formed in outer surfaces of the blocks and/or disposed through a volume of the blocks. The modular blocks can have a uniform design across various block types, making it easy to reconfigure systems and/or remove and replace blocks and other components of the system. Methods for constructing such systems, and using such systems, are also provided.

Abstract: The invention relates to the balancing of fluid streams in a dialysis system. In particular the invention relates to a cassette for conveying a first and a second fluid stream in a dialysis system, wherein the first and the second fluid streams can be medical fluid streams such as for example dialysate streams or blood streams, wherein the cassette has a sensor as a device for balancing the first and the second fluid stream, and wherein the sensor has a first channel for the first fluid stream and a second channel for the second fluid stream. The invention further relates to a dialysis system, which is configured to accommodate at least one cassette which is configured as described above. Furthermore, the present invention relates to an arrangement by which two channels for the first and the second fluid streams are formed. In addition, the invention relates to a method for construction of the two channels or the arrangement.

Abstract: Disclosed are devices for the controlled handling and delivery of solutions, as well as methods of making and using thereof. The devices can comprise a nanoporous membrane having a top surface and a bottom surface; a fluid source positioned in fluid contact with the bottom surface of the nanoporous membrane; and an electrode patterned on one or more of the surfaces of the nanoporous. membrane (e.g., on the top surface of the nanoporous membrane, on the bottom surface of the nanoporous membrane, or on both the top surface and the bottom surface of the nanoporous membrane). The electrode or electrodes are patterned so as to define a fluid delivery region in fluid contact with the top surface of the nanoporous membrane.

Abstract: A device is provided for measuring physical properties of a sample material having a body comprising a chamber adapted to receive a sample material and a transducer electrically connected to a circuit. The transducer is arranged on the body of the device to contact the body such that the body is able to transmit vibrations between the sample material and the transducer. A drive unit is electrically connectable to the circuit to measure physical properties of the sample material.

Abstract: A microfluidic distributing device having a plurality of microchannels for the analysis of a fluid sample (such as blood). The microfluidic distributing device has a fluid sample entry port from which subsamples of the fluid sample are distributed to the plurality of microchannels in which fluid subsamples are treated for analysis by test devices.

Abstract: A fluidic oscillator adapted for use in a showerhead or nozzle assembly includes an eddy filter structure which reduces the adverse effects of fluid supply turbulence on the fluidic oscillator's spraying performance. A nozzle or rain can style showerhead assembly includes a water chamber or manifold which receives water via a central inlet fitting. Water entering the water chamber or manifold flows turbulently into and through the manifold and is expelled under pressure through a plurality of nozzles which are configured as specially adapted fluidic inserts.

Abstract: Provided is a vapor jetting device including: a box-shaped casing; a propellant holding unit that is placed in the casing and forms a space for holding a propellant; a gas storing unit that is placed in the casing, forms a space that is divided from the propellant holding unit by a partition wall including a communication hole, and stores gas; a machine housing unit that is placed in the casing, forms a space that is divided from the propellant holding unit and the gas storing unit by partition walls, and houses machines; a nozzle that is connected to the casing and ejects the gas to an outside; a gas flow path that is formed in the casing and supplies the gas stored in the gas storing unit to the nozzle; and a heater that is placed in the casing and heats at least the gas storing unit.

Abstract: Methods and devices are disclosed for providing the controlled formation of planar homogeneous or heterogeneous materials using microfluidic devices. In one embodiment, a planar array of microfluidic channels is employed to produce a flowing liquid sheet having heterogeneous structure by spatially and temporally controlling dispensing of polymer liquid from selected microchannels. The resulting liquid sheet is solidified to produce a planar heterogeneous material that may be continuously drawn and/or fed from the plurality of microfluidic channels. The polymer liquid may include a payload that may be selectively incorporated into the heterogeneous structure. In some embodiments, the local material composition is controllable, thereby allowing control over local and bulk material properties, such as the permeability and the elasticity, and of creating materials with directionally dependent properties.

Abstract: A flow rate measuring device includes: a bypass passage; a flow rate detecting element; and a flow rate measuring circuit. The bypass passage includes: an inflow port; an outflow port; and a plurality of bent portions. The plurality of bent portions include first to third bent portions for forming U-shapes, and a fourth bent portion for bending the bypass passage bent at the third bent portion so as to be parallel to a mainstream flowing direction. The flow rate detecting element is arranged inside the bypass passage in a part after bending at the fourth bent portion. A route connecting the inflow port and the flow rate detecting element as a straight line is blocked by an inner wall surface of the bypass passage on an outer peripheral side, which is formed between the first bent portion and the second bent portion.

Abstract: A multiple polymer layer test cartridge includes an input to receive a sample containing cells, multiple lysing channel structures on alternate layers of the multiple layer test cartridge coupled to each other to pass the sample in sequence between the lysing channel structures, and a test chamber to receive the sample from the multiple lysing channel structures.

Abstract: A microsystem for fluidic applications includes a substrate with a reservoir, a first microchannel, connected to the reservoir, and a second microchannel, separated from the first microchannel by a fixed member. The microsystem furthermore has an elastic film on the substrate, which film has a joint to the substrate around the reservoir and seals the reservoir. Here, the joint has a permanent joining area and, on the fixed member, a fixed member joining area that can be broken open and adjoins the permanent joining area at both ends of the fixed member. Such a microsystem forms a processing chip with reagent receptacle.

Abstract: A continuous reaction micro-reactor of modular structure comprises, arranged along a back-to-front stacking axis thereof, a first frame means, a reaction unit, and a second frame means, wherein said reaction unit comprises a process fluid channel system for continuous reaction of a plurality of feeds or reactants flowing into said reaction unit to form at least one product flowing out of said reaction unit, and a heat exchange fluid channel system for adjusting the temperature environment of said process fluid channel system, said first and second frame means are each formed as a flange, and said first and second frame means are alpressed towards each other by a plurality of tensioning means arranged along and within an outer circumference of said first and second frame means and enclosing said reaction unit.

Abstract: A micro fluid chip includes a first chip and a second chip. The first chip includes a first substrate having a fluid channel and a partition wall, and a first film made of resin. The second chip includes a second substrate having a recess, and a second film made of elastomer. The second film has an elastic modulus higher than that of the first film. The first chip and the second chip are stacked in such a manner that the partition wall and the recess face each other with the first film and the second film therebetween. By setting the inner side of the recess to a negative pressure, a gap is formed between the first film and the partition wall, and thus a fluid channel is opened.

Abstract: Methods and systems capturing particles suspended in a fluid flowed through a micro-channel, can include flowing the fluid including the particles to be captured through a micro-channel and past a groove defined in a surface of a wall of the micro-channel such that flowing the fluid past the groove forms microvortices in the fluid; contacting at least some of the particles against an adherent disposed on one or more of walls of the microchannel after the microvortices form in the fluid; and capturing at least some of the particles contacting the adherent.

Abstract: A diverter, and a cooking chamber and cooking apparatus including the diverter, is capable of diffusing liquids, semi-solid substances, and the like. The diverter includes a diverter plate and an orifice that projects from a surface of the diverter plate. The orifice has an open sidewall portion. The diverter further includes a recessed portion formed in the diverter plate, extending from the orifice, and a bumper portion that projects from a surface of the recessed portion and is disposed proximate to the orifice. The cooking chamber includes a heating element, a wall, an inlet port formed in the wall, and a cooking chamber fitting disposed adjacent to the inlet port. The cooking apparatus includes a cooking chamber, a filter pan, a filter pump, and an inlet port formed in a wall of the cooking chamber.

Abstract: An apparatus is disclosed for mixing a first stream of a flow medium and a second stream of the flow medium, a temperature of the first and second streams being different. In an embodiment, the apparatus includes at least one mixing apparatus configured as a blade-free fan, including at least one opening and a Coanda surface arranged in the region of the at least one opening. During operation, the first stream emerges from the at least one opening and can be steered by the Coanda surface, wherein the second stream flows in the region of the at least one opening, and wherein the first stream, following the emergence thereof from the at least one opening, is mixable with the second stream. The apparatus also includes a first infeed for the first stream and a second infeed for the second stream, first and second infeeds being configured as a double-walled tube.

Abstract: A Coanda flow amplifier has a suction intake, an outlet, a fluid channel extending between the suction intake and the outlet, and a drive-flow inlet, which is fluidly connected to the fluid channel via a drive-flow discharge slit, whereby the flow cross section of the drive-flow discharge slit is variably adjustable. In a method to operate the Coanda flow amplifier, the variably adjustable flow cross section of the drive-flow discharge slit is chosen such that a pressure ratio between an output pressure of the drive flow when it leaves the drive-flow discharge slit, and an intake pressure of the drive flow when it enters the drive-flow discharge slit, does not exceed a critical pressure ratio. A fuel cell system comprises at least one fuel cell, a fluid source, a fluid line, and a Coanda flow amplifier arranged in the fluid line, whereby the Coanda flow amplifier is equipped with a drive-flow discharge slit with a variably adjustable flow cross section.

Abstract: Bottomed first regions 23a? and 23b?, and second regions 24a? and 24b? are formed by joining film 14 to undersurface 21 of chip body 12 of a micro-channel chip. Third regions 25a? and 25b? are formed between first regions 23a? and 23b?, and second regions 24a? and 24b? so as to be located on carbon inks 16a and 16b. The width of third regions 25a? and 25b? is formed so as to be greater than the width of carbon inks 16a and 16b.

Abstract: Electro-osmosis is used to create droplets in order to easily, carefully, and quickly pick-and-place millions of objects (ranging in size from millimeters to nanometers) individually or in parallel. Droplets are formed within channels that are individually controlled in order to achieve a predetermined configuration of the selected objects.

Abstract: To promote mixture of fluids on a plurality of stages, flow channels include a plurality of merging portions which penetrate from a top surface to a back surface of a substrate. An end of each of the sub channels is disposed so as to overlap the main channel at each of positions separated along the direction in which the main channel extends, and each of the merging portions communicates the main channels and the ends of the sub channels with each other, thereby changing a flow direction of the second fluid flowing through the sub channels to the thickness direction of the substrate, and merges the second fluid with the first fluid flowing through the main channels.

Abstract: A fluid tube includes: a first fluid tube; a second fluid tube connected to the first fluid tube; and a flow velocity equalizer in the second fluid tube, where the flow velocity equalizer increases a uniformity of fluid flow passed therethrough, the second fluid tube is wider than the first fluid tube, and the flow velocity equalizer includes a diverging tube and a converging tube. The fluid tube may further include a fluid divider between the flow velocity equalizer and the first fluid tube. The diverging tube of the flow velocity equalizer may have a width increasing in a fluid flow direction, and the converging tube of the flow velocity equalizer may include a plurality of converging tubes having widths decreasing in the fluid flow direction.

Abstract: Pressure compensators (1) for stabilizing a flow of water are disclosed. The pressure compensator (1) includes water compensating channels (3) formed on the outer periphery of their body (2), and flow orifices (4) passing through the pressure compensator (1), so that the water compensating channels and the flow orifices control the flow rate of the water at varying pressures. The body of the pressure compensator (1) preferably comprises a flexible material, such as rubber.

Abstract: A microfluidic device for transporting a fluid, in particular a micropump or microvalve. The device has films, which lie against each other at film surfaces facing each other and are connected to each other in such a way that a transport channel to be formed between the films is defined, Deflecting apparatuses for forming the transport channel by jointly deflecting the films lie against each other in a direction perpendicular to the film surfaces. A deflecting surface region of the rear film in the deflection direction lies within the deflecting surface region of the front film in the deflection direction defined by the connection between the films.

Abstract: A microfluidic device for generation of monodisperse droplets and initiating a chemical reaction is provided. The microfluidic device includes a first input microchannel having a first dimension and including a first phase located therein. The device also includes a second input microchannel having a second dimension and including a second phase located therein. In accordance with the present disclosure, the second dimension is different from the first dimension and the first phase is immiscible in the second phase. A microchannel junction is also present and is in communication with the first input microchannel and the second input microchannel. The device further includes an output channel in communication with the microchannel junction and set to receive a monodisperse droplet. In the present disclosure, the difference in the first dimension and the second dimension creates an interfacial tension induced force at the microchannel junction which forms the monodisperse droplet.

Abstract: An ejector includes a nozzle having a fluid passage circular in cross section. The fluid passage includes a throat portion smallest in cross-sectional area, a divergent portion that becomes larger in cross-sectional area toward a downstream side from the throat portion, and an ejection port that is provided at a downstream end of the divergent portion. A passage wall surface of the divergent portion includes a recess portion that is recessed from within outward in a radial direction of the passage wall surface. The recess portion is located adjacent to the ejection port, and the recess portion extends continuously in a circumferential direction of the passage wall surface to enclose the fluid passage and have an annular shape. Accordingly, noise due to an expansion wave of the ejected fluid can be reduced.

Abstract: The invention relates to a device and method for manipulating a liquid in a channel, wherein a body, which forms a capillary intermediate space with respect to the channel wall, is moved in the channel and the channel is filled with liquid only up to the body. Preferably, the body can also bridge an area of the channel that cannot be wetted for the liquid.

Abstract: A fluid path structure is manufactured by way of an aligning step of aligning a first resin part with a second resin part by inserting a projection formed on the first resin part into a corresponding hole formed in the second resin part and a welding step of welding joint surfaces of the first resin part and the second resin part, thereby forming a fluid path. The aligning step is executed so as to narrow the gap between the projection and the hole to a minimum at a base side of the projection relative to a half of the height of the hole and the welding step is executed only at the base side of the projection relative to the half of the height of the hole so as to make the lateral surface of the projection only partially contact with the lateral surface of the hole.

Abstract: Provided is a method of controlling water droplet movement including providing a substrate including a superhydrophobic surface on which a hydrophilic channel guiding water droplet movement is patterned, introducing a water droplet on the substrate, and modulating a slope of the superhydrophobic surface for the water droplet to move on the superhydrophobic surface along the hydrophilic channel. Here, a width of the hydrophilic channel is modulated for the water droplet to move on the superhydrophobic surface having a certain angle with respect to a ground.

Abstract: A pinch valve, a chip including the pinch valve, a peristaltic pump including the pinch valve and a method for manufacturing the pinch valve. The pinch valve includes a first substrate, a second substrate, and a third substrate. The third substrate is formed from an elastic material and situated between the first and second substrates. The first substrate adjoins the third substrate and includes at least one first recess on the side adjacent to the third substrate. The second substrate adjoins the third substrate and includes at least one second recess on the side adjacent to the third substrate. The first recess and the second recess are situated at least partially opposite each other.

Abstract: Chip body 130 in which a through hole or concave is formed, intermediate film 140, on one surface of which adhesive layer 150? is formed and lower film 170, on one surface of which transfer function layer 160 is formed, are prepared. Intermediate film 140 and lower film 170 are bonded together such that transfer function layer 160 is embedded in adhesive layer 150? to form a laminated body. The laminated body and chip body 130 are bonded together by thermocompression to manufacture micro-chip 100.