Abstract: The invention concerns an interfacing device (1) intended to connect a fluid injection instrument and a puncturable flask (2), comprising: a base (10) suitable for connecting the interfacing device (1) to the fluid injection instrument, an attachment means for attaching (20) the base (10) to the puncturable flask (2), arranged at a distal end (1a) of the interfacing device (1), characterized in that the attachment means for attaching (20) has a divergent proximal end (21) forming a shoulder and a convergent distal end (22) suitable for facilitating the penetration of the attachment means for attaching (20) into the puncturable flask (2).

Abstract: A containing device includes a container; a compressed gas source in the container and including a sealed opening; a channel member having a first end releasably secured to a first end of the container and including through holes; a hollow closure member releasably secured to a second end of the container; a hollow striker including a projection and a hollow needle spaced from the opening; and two opposite apertures through a periphery of the projection; a cap releasably secured to a second end of the channel member; a biasing member biased between the cap and an internal space of the striker; and a pull ring inserted through the through holes and the apertures to hold the striker in place in a locked position. A pulling of the pull ring out of the channel member can trigger a release of high-pressure gas.

Abstract: The drug delivery device (1) connects an syringe barrel (6) and a drug container (2) by means of a closed system, and delivers a drug between the syringe barrel and drug container through said closed system. This drug delivery device includes a first member (8) connected to the drug container (2) on the side of a stopper (4), and a second member (30) connected at one end to the first member and connected at the other end to the syringe barrel (6). The first member and the second member are connected by a fitting mechanism. A second hollow needle member (34) provided on the second member faces towards the first member, and the tip portion (36) and the base portion (38) are fixed. The first member has a first hollow needle member (12). The first member and the second member each have an elastic member (18 and 40).

Abstract: A temperature measurement system includes a temperature probe having a head and an infrared temperature sensor disposed in the head. The system also includes a replaceable probe cover removably attachable to the head. The probe cover includes a body, a substantially cylindrical waveguide extending from the body, and a distal tip. The waveguide is configured to direct radiation entering the distal tip to the temperature sensor when the probe cover is attached to the head.

Abstract: A sampling port (10) has a body (12) having an space (35) open at one end (20) and adapted to receive a sampling vial (70) with an cannula (24) extending longitudinally along the space (35) with a pointed end (26) facing the open end (20), whereby a sampling vial passed into the space from the open end may be impaled on the cannula. The port includes at least one guide member (36) extending into the space (35) to reduce the effective size of part of the space (35), the at least one guide member (36) guiding a vial (50) of a first size when inserted into the open end (20) and the at least one guide member (36) being movable to allow a vial (70) of a size larger than the first size to be inserted into the space.

Abstract: Implementations of the present invention relate to systems, methods, and apparatus for inflating objects. Particularly, at least one implementation includes a semi-flexible inflation needle that can bend without breaking Furthermore, at least one implementation includes a semi-flexible inflation needle that includes a cut out portion as a safety feature.

Abstract: A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.

Abstract: A reusable aseptic connector is provided. The connector may be used to provide fluid communication between a bag-in-box (BIB) container and a beverage dispenser. The connector may provide aseptic properties of the connection by insulation of an inner volume of a first part and an inner volume of a second part, with the beverage component kept from contacting any of the part of the connector structure that are exposed to the environment and have a risk of induced contamination. The connector may comprise a resilient membrane and a sliding tube wherein the sliding tube is configured to have a portion move toward and through the resilient membrane to establish fluid communication between the first part and the second part, and for the portion to move away from the resilient membrane to destablish fluid communication between the first part and the second part when desired.

Abstract: A container (1, 2) for storing and dispensing a liquid, the container including an access port (16) having a frangible seal (18) for allowing contained liquid to be dispensed. A vent (19) permeable to vapour but impermeable to liquid is also provided so that vapour may be vented from the interior of the container.

Abstract: A system (10) for removing a pipettable substance from a pre-filled container (20), which is closed off by a top (30) having at least one opening area (40), comprises an opening tool (100) having a tube (110), which has a cross-section corresponding substantially to the shape of the opening area and which comprises at a distal end (120) an endpiece (140) extending substantially obliquely relative to the longitudinal axis of the tube, which moves a part of the top (30) located inside the opening area (40) towards the container when the opening tool is applied, so as to form an opening in the top, and a point of attack (150) for a transporting tool (200). The opening tool (100) is designed to remain on the container (20) after use.

Abstract: A device connecting a recipient closed by a perforatable stopper and a container for a needle, comprising a base for mounting the container, the base defining a central bore and comprising means for mounting on the recipient, the needle pertaining to a subset engaged in the central bore forming part of the device, for mounting on the container, and being arranged in the central bore parallel to the bore's longitudinal axis, and a sealing sleeve arranged in the central bore, around the needle and in contact therewith, the base being a single component and comprising a body for perforating the stopper extending from an intermediate wall of the base, away from the central bore and parallel to its central axis, up to a distal end, the perforating body being hollow and the inner space thereof communicating with the central bore and with a space radially surrounding its distal end.

Abstract: Disclosed is a closure device for a container, which seals an opening (6) that opens at the top of a container (2) and has a rim (7) on its periphery. The closure device comprises a seal member (8) that is to cover the opening (6) on the top of the container (2), and a synthetic resin cap (9) that is to press the seal member (8) against the upper surface of the rim (7). The seal member (8) comprises a flange (10) to be mounted on the upper surface of the rim (7). The cap (9) comprises a top wall (15), a cylinder part (16), and a locking part (18). The top wall (15) is to be disposed above the flange (10). The cylinder part (16) hangs down from the outer circumference of the top wall (15). The locking part (18) is disposed on the inner surface of the cylinder part (16). After the cap (9) is pushed down, the locking part (18) locks at the under surface of the rim (7). The upper surface of the flange (10) has a compressible projection (29).

Abstract: Some embodiments disclosed herein related to a device for transferring precise amounts of fluid from at least one source container to a at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container.

Abstract: The invention relates to a method and a device for the sterile filling of a disposable injector with a defined dose of an injection solution, wherein the disposable injector comprises a cylinder/piston unit with a cylinder and with a piston that can be pulled back manually. The defined dose of the injection solution is stored in an interior of a container of a needle syringe held in a bored stopper. The cylinder interior is connected to the container interior in a gas-tight and liquid-tight manner through the bored stopper. The cylinder/piston unit is filled by pulling back the piston or by pressing the needle syringe piston. With the present invention, a method and a device for filling a disposable injector are developed in which, without intermediate weighing or risk of inaccurate readings, the disposable injector can be filled with a defined dose of an injection solution from a syringe with a fused-in needle.

Abstract: A container and method for filling same. The container includes a penetrable and resealable portion that is resealable, and a container body having a sealed empty chamber in fluid communication with the penetrable and resealable portion for receiving therein a substance. The container also includes a base, a mid-portion, and an upper portion axially spaced from the base on an opposite side of the mid-portion relative to the base. Each of the base and upper portion define a laterally-extending dimension greater than a maximum laterally-extending dimension of the mid-portion. The method of filling the container includes penetrating the penetrable and resealable portion with an injection member and introducing a substance into the chamber, withdrawing the injection member while engaging the base of the body to substantially prevent upward movement of the body, and applying energy to the penetrable and resealable portion to form a gas-tight seal.

Abstract: A fluid delivery system for dispensing a liquid from a sealed container directly into a closed chamber comprises a container containing a liquid component of bone cement and plugged with a plug, and a closed chamber comprising a receiving port for receiving the sealed container, wherein the receiving port is configured to receive the liquid component in direct response to manual insertion of the sealed container through the receiving port using an open loop system.

Abstract: A sealing cap for a body fluid container, and a body fluid collection device and system are disclosed. The sealing cap includes an inner cap placeable on an opening in the body fluid container forming a mouth, the inner cap has a shielding member which seals the mouth of the body fluid container, an outer cap resting on the inner cap, the outer cap being movable relative to the inner cap, and a channel member, wherein by a rotational movement the outer cap is movable between an first position in which the channel member is located separated from the shielding member and a second position in which the channel member extends through the shielding member, thereby establishing an open state of the shielding member, and wherein the shielding member returns to a closed state when the outer cap is moved back from the second position to the first position.

Abstract: A vented needle comprises a distal end configured to pierce a seal of a first container having a top and a bottom surface and a seal of a second container having a top and a bottom surface. An interior lumen is configured to fluidly couple the first container and a fluid transfer device and the second container and the fluid transfer device. A middle portion is configured to engage the seals of the first container and the second container and having one or more axially extending vents. At least one of the one or more vents is configured to extend axially past the top and bottom surfaces of the seal of the first container and configured to fluidly couple the first container and ambient air outside the first container. None of the one or more vents are configured to extend axially past top and bottom surfaces of the seal of the second container.

Abstract: An apparatus for feeding a product to be packaged to a packaging machine provided with a dosing unit, comprises a lifting arrangement suitable for lifting and moving at least a container of the product in such a way as to connect the container to the dosing unit to transfer thereto the product contained in the container; a method for feeding a product to be packaged to a packaging machine provided with a dosing unit by the apparatus, comprises the steps of introducing a container of product inside the apparatus, fixing the container to a lifting arrangement of the apparatus, moving the container using the lifting arrangement in such a way as to connect it to the dosing unit, transferring the product contained in the container to the dosing unit.

Abstract: Valve assemblies for use with a liquid container and a drug vial for enabling an initial transfer of liquid contents from the liquid container to the drug vial for liquid drug formation purposes and subsequent transfer of liquid drug contents from the drug vial to the liquid container for administration purposes. Liquid drug transfer sets can include a valve assembly pre-attached to a liquid container. Alternatively, liquid drug transfer sets can include a valve assembly packaged in sterile blister packaging ready for attachment to a liquid container prior to use.

Abstract: The present invention provides a printing liquid container, a printing liquid filled container, an image forming apparatus, and a printing liquid filled container manufacturing method that may enlarge the opening surface area in a seal membrane. Namely, the printing liquid container includes: a sealing membrane provided to a capping section for sealing an opening in the capping section; a contact portion formed in a central portion of the sealing membrane, the contact portion is contacted by a hole piercing tool for forming a hole in the sealing membrane; and a first rupture portion configured thinner than the sealing membrane and extending out from the contact portion to an outer peripheral portion of the sealing membrane.

Abstract: A device that has a device body defining an opening at one end thereof, a storage chamber within the device body for storing multiple doses of a substance therein, and a sliding stopper, sealing engageable with the device body, through which the chamber is filled. The stopper has a body and a flexible portion, which may be in the form of a plurality of flexible members, extending therefrom. The flexible portion or members are movable between first and second positions. In the first position, during filling, the portion or members are substantially laterally extending from the stopper body and engaging the opening of the device body. Accordingly, the axial position of the stopper with respect to the device body is secured during filling of the chamber therethrough. In the second position, after filling, the portion or members are substantially axially-extending from the stopper body and disengaged from the rim or opening of the device body. Accordingly, the stopper is axially slideable through the body.

Abstract: A machine for the automatic preparation of an intravenous medication is provided. In one implementation the machine has a chamber with a starting products area where at least one receptacle is disposed with a base product from which the intravenous medication is generated, a transfer tools area where at least one transfer tool that is used to prepare the required medication is disposed, a prepared products area where at least one container to house the prepared medication is disposed, and a first robot to handle the transfer tool, the first robot being adapted to transport the transfer tool between the transfer tools area, the starting products area and the prepared products area in order to prepare the intravenous medication.

Abstract: A pierce and fill connector cap for a vial sealed by an elastomeric septum includes a vial collar and a needle holder. The vial collar body defines a collar aperture to be positioned in overlying registry with the septum of the vial, and the needle holder includes a needle holder body providing a means for holding a pair of elongate needles in registry with the collar aperture. The needle holder body holds at least one needle therein in a bent or deflected orientation and is moveable with respect to the vial collar between a first position spaced from the vial collar and a second position proximate the vial collar, such that the needled held by the needle holder will puncture through the vial septum.

Abstract: Method and machine for the preparation of pharmaceutical products according to which a container containing a liquid phase and a gaseous phase is connected to an aspiration circuit of a given amount of the liquid phase; a flow sensor being provided for detecting the passage of the liquid phase and of the gaseous phase along the aspiration circuit.

Abstract: An automated reservoir filling system for a portable medical device is disclosed. The system includes a vial sealed by a septum partially filled with a liquid and a gas occupying a headspace. The system further includes a reservoir with a volume defined between a reservoir septum and a plunger head. The plunger head is coupled to a plunger arm which is further coupled to a drive system. Further included is a transfer system with a vial end that pierces the vial septum and remains in contact with the liquid, and a reservoir end that pierces the reservoir septum and remains in the reservoir volume. A controller coupled to the drive system to actuates the drive system automatically drawing fluid from the vial to the reservoir through the degas system.

Abstract: The invention concerns a new food product (1) in the form of a meal comprising food (4) and a sauce (5), intended to be mixed for consumption of the meal, in closed packaging (1) comprising a container (2) in which the food (4) is placed and a lid (3) in which the sauce (5) is placed, the sauce being separated from the food by a seal (7) which closes off the part of the lid (3) facing the food (4) characterized in that the container (2) comprises a mechanism (11) to tear the seal (7) when the lid (3) is turned concurrently to the container (2) between a pre-tearing position of the seal (7) and a tearing position of the seal (7).

Abstract: A liquid injection jig set includes a chip receiver in which a microchip having a plate shape is received in a case, and a jig that is configured to be fittable to the chip receiver includes a hollow needle that can pierce a side end surface of the microchip, which is exposed from the case, and introduces liquid into the microchip via the hollow needle.

Abstract: A dosage dispenser according to the invention is intended to provide a solution for measuring and dilution of liquid medications and issuing marked and ready for use. The dosage dispenser device carries out actions required for the preparation of a required dose of medication, including identifying ampoules, breaking them, filling a syringe, diluting the medication in a solution, marking the syringe, disposing of waste and documenting the process, all at the patient bedside. The dosage dispenser is aimed at reducing the number of errors in the dosage, which is a problem, menacing medical services throughout the world. The problem is made acute by considerable pressure on the medical teams while carrying out many and complex procedures under pressure in a situation of uncertainty and with variable data.

Abstract: One-piece dispensing closure or lid molded in a single mold not requiring assembly of independent pieces, except for a seal after filling the closure with the additive. The closure has a round side skirt and security or tamper evident band, provided inside with threaded ribs, a flexible diaphragm with a tearing structure made up of a central stem and a tearing cylinder having a plurality of tearing tips to break the seal and release the additive.

Abstract: Liquid drug transfer assemblies for use with a drug vial having a drug vial opening stopped by a drug vial stopper. The liquid drug transfer assemblies include a drug vial stopper puncturing member for puncturing a drug vial stopper. The liquid drug transfer assemblies also include a drug vial adapter having a drug vial adapter skirt, an upright drug vial adapter port and a drug vial adapter sleeve downward depending opposite the upright drug vial adapter port and in flow communication therewith. The drug vial adapter is slidingly disposed on the drug vial stopper puncturing member such that on mounting the liquid drug transfer assembly on the drug vial, the drug vial stopper puncturing member punctures the drug vial stopper to form a throughgoing puncture bore and the drug vial adapter sleeve lines the puncture bore.

Abstract: Arrangement and method for injecting a fluid into an analysis appliance, in particular into a liquid chromatograph with an injection opening. The arrangement includes a manipulating device with an injection needle, and a seal, in particular a ferrule, which is made of a polymer material and is arranged removably on the injection opening. In the axial direction, the seal has a guide bore for receiving the injection needle. The guide bore includes a shoulder with an opening, of which the diameter is smaller than a diameter in a first portion of the guide bore extending from the shoulder in the direction of a first end of the seal. The injection needle can be inserted into the guide bore from the direction of the first end of the seal, and the front edge of the injection needle can be pressed onto the shoulder with a predetermined force.

Abstract: A fluid connector for selectively establishing fluid communication between a first medical container and a second medical container is provided. The fluid connector includes an adapter configured to removably attach to the first container. The adapter includes an access port and a cap. The connector further includes an outer sleeve connected to the adapter and a tubular body retained at least partially within the outer sleeve. The body has a proximal end connected to the adapter and a distal end connected to the second container. The fluid connector is transitionable from a first position in which the first container and the second container are in fluid isolation to a second position in which the first container and the second container are in fluid communication. At least a portion of the cap of the adapter is retained within the outer sleeve.

Abstract: An assembly includes a support and drive assembly, a first structure and a second structure. The first structure is in operable communication with and supported by the support and drive assembly. The first structure includes at least one filling or needle assembly and is adjustable to receive a plurality of filling or needle assemblies. The second structure is supported by the support and drive assembly. The second structure includes at least one seal assembly and is adjustable to receive a plurality of seal assemblies. A method includes determining a number of containers or vials that are to be filled concurrently and adjusting an assembly to include at least one filling or needle assembly and at least one seal assembly. A number of the filling or needle assemblies and the seal assemblies equals the number of containers or vials.

Abstract: A hollow needle comprising a shaft having a distal portion suitable for passing through an elastomer closure of a container, said shaft extending in a longitudinal direction and having a central longitudinal axis, and having an internal longitudinal conduit therein for the flow of liquid and one or more orifices communicating between the conduit and the exterior of the needle, the distal portion of the shaft being provided with a pointed end that has a profile comprising a cutting edge in the form of two part cutting edges converging in the longitudinal direction to meet at the needle point, each part cutting edge extending in a straight line in a widthways direction across a plane including the central longitudinal axis, on both widthways sides of the cutting edge the pointed end having a profile which is a non-cutting surface, wherein the pointed end of the needle tapers from an outer surface of said distal portion toward the point of the needle, and the distance, measured in a further plane defined by said

Abstract: A device connecting a recipient closed by a perforatable stopper and a container for a needle, comprising a base for mounting the container, the base defining a central bore and comprising means for mounting on the recipient, the needle pertaining to a subset engaged in the central bore forming part of the device, for mounting on the container, and being arranged in the central bore parallel to the bore's longitudinal axis, and a sealing sleeve arranged in the central bore, around the needle and in contact therewith, the base being a single component and comprising a body for perforating the stopper extending from an intermediate wall of the base, away from the central bore and parallel to its central axis, up to a distal end, the perforating body being hollow and the inner space thereof communicating with the central bore and with a space radially surrounding its distal end.

Abstract: Garden torches, hurricane lanterns and other oil lamps can be refueled through a flexible hose terminating in a tube or hollow needle insertable into the lamp's fuel reservoir through a wick slot. This method avoids skin contact with fuel and with soot deposited on the oil lamp reservoir.

Abstract: An apparatus for the handling of hazardous fluids includes a collection vessel, a collection vessel connector, a dose control connector, a unit dose container, a delivery control connector, and a delivery site access device. The collection vessel contains the fluid prior to dispensing, the unit dose container contains a predetermined amount of the fluid for dispensing, the delivery site access device provides access to an intended delivery site, and the connector attaches pieces of the apparatus to one another. The method of the invention allows needle-free connections to be made for the apparatus, using a predetermined arrangement of the pieces of the apparatus, and in one embodiment, employs deformable elastomeric valves capable of creating a decreased pressure at a valve surface, so that upon closure of said valves, a fluid on the surface on the valves is withdrawn within the connector.

Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.

Abstract: A syringe-to-syringe mixing apparatus comprises first and second syringes adapted to be coupled at their respective outlets to fluidly connect the syringes. The first syringe includes a plunger having a hollow plunger barrel and a distal end defining a lumen therethrough. The lumen is initially closed by a septum, which in one embodiment is an elastomeric stopper mounted over the end of the plunger. The mixing apparatus further includes a third syringe slidably disposed within the plunger barrel. The third syringe includes a hollow needle adapted to pierce the septum to allow fluid from the third syringe to be injected into fluid within the coupled first and second syringes.

Abstract: A novel system for safely transferring liquids from containers such as plastic jugs that are sealed by frangible seals, to conventional drums of the character having coupler-operated extractor valves. In one form of the invention, a standard coupler mechanism has been modified in a manner to provide means for rupturing the frangible seal of the sealed container without adversely affecting the manner in which the coupler is used to operate the extractor valve that is carried by the drum to which the liquid is to be transferred. Additionally, a novel adapter member has been provided for interconnecting the sealed container to the coupler mechanism.

Abstract: A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position.

Abstract: Devices and methods are disclosed for extracting fluids from within a container sealed by a cork or septum without removal of the cork or septum or the contamination of the fluid within the container by reactive gases or liquids. Embodiments of the device can include a needle connected to a valve which is in turn connected to a source of pressurized gas for displacing the fluid. Further embodiments of the device can comprise additional components that act to force the needle to be inserted through the cork or septum along a linear path, to aid in preventing buckling of the needle, to clamp the device to the container, to prevent expulsion of the cork or septum from the container, and to guide the needle through a specified region of the cork or septum. Various valves, pressure regulators, pressure ranges, needle geometries, gas selections are also presented. This device is particularly suited for the dispensing and preservation of wine.

Abstract: Apparatus for filling containers having stoppers that are penetrable for filling the containers with a substance, and thermally resealable for thermally sealing the resulting hole. A container support supports at least one such container in a substantially fixed position during filling and resealing. A manifold drivingly mounted over the container support comprises (1) a cartridge including a filling needle for penetrating the resealable stopper and introducing a substance therethrough into the container, a mount for mounting the cartridge on the manifold, and a removable cover releasably coupled to the mount for covering the filling needle during transportation, installation and/or removal of the cartridge from the manifold. The manifold includes a thermal source for heating a penetrated region of the stopper and, sealing the hole.

Abstract: A filling element for free jet filling of containers with liquid contents that contain solid constituents includes a housing, a contents chamber formed in the housing, and a liquid valve in the contents housing. The liquid valve comprises a valve body, and a valve opening. The valve body undergoes movement between a first position and a second position. In the first position, the valve body closes the valve opening, thereby locking the liquid valve. In the second position the valve body releases the valve opening and opens the liquid valve. The valve body is moved such that closing the valve occurs without a pump effect on the liquid contents.

Abstract: A robotic intravenous automation system, including a robotically controlled holder configured to manipulate an intravenous (IV) bag and a closed system transfer device (CSTD). The controller includes a processor configured to control the holder. The IV bag includes a first fluid port and a second fluid port, and the CSTD includes a CSTD port, a spike adapter that is fluidically separated from the CSTD port, and a flexible member connecting the CSTD port to the spike adapter.

Abstract: A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

Abstract: Liquid drug transfer assemblies for use with a drug vial having a drug vial opening stopped by a drug vial stopper. The liquid drug transfer assemblies include a drug vial stopper puncturing member for puncturing a drug vial stopper. The liquid drug transfer assemblies also include a drug vial adapter having a drug vial adapter skirt, an upright drug vial adapter port and a drug vial adapter sleeve downward depending opposite the upright drug vial adapter port and in flow communication therewith. The drug vial adapter is slidingly disposed on the drug vial stopper puncturing member such that on mounting the liquid drug transfer assembly on the drug vial, the drug vial stopper puncturing member punctures the drug vial stopper to form a throughgoing puncture bore and the drug vial adapter sleeve lines the puncture bore.

Abstract: Device and method for needle penetrating and filling a chamber with a predetermined substance, and hermetically resealing a resulting needle hole in the device by applying radiation thereto. The needle penetrable and resealable portion defines a predetermined wall thickness in an axial direction thereof, and may include a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and resealable portion during penetration by and withdrawal of the needle. Such thermoplastic may include a predetermined amount of pigment that allows the thermoplastic to substantially absorb laser radiation at a predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period.

Abstract: This present disclosure provides a non-coring vial access cannula which has sufficient structural strength that it may be made from a thermoplastic resin instead of metal, thus reducing the likelihood and severity of operator injury by an accidental needle stick. The vial access cannula of the present disclosure has (i) a needle hub suitable for receiving a hypodermic syringe or an IV set (e.g., a Luer lock), (ii) a cannula portion having a centrally disposed lumen, wherein the centrally disposed lumen terminates in one or more distal openings and is in fluid communication with the needle hub, and (iii) a solid tip member distal to the one or more distal openings, wherein the solid tip member has a blade with a cutting edge.