Abstract: Protein phosphorylation is a major post-translational modification and it plays a pivotal role in numerous cellular functions. We present a composition that includes a soluble nanopolymer core functionalized with groups having an affinity for either metal ion or metal oxides which can be used for phosphopeptide enrichment. Exemplary compounds including PolyMAC-Zr, PolyMAC-Fe and PolyMAC-Ti demonstrate outstanding reproducibility, exceptional sensitivity, fast chelation time, and high phosphopeptide recovery from standard mixtures that include phosphorylated peptides. The composition can be used for phosphoproteome isolation from samples of medicinal, diagnostic or biological interest such as malignant breast cancer cells. Such compositions were used for the quantitative analysis of the changes in the tyrosine phosphoproteome in highly invasive breast cancer cells after induction of Syk kinase, a potent suppressor of tumor growth and metastasis.

Abstract: The aim of the invention is to effectively inhibit virus-, bacteria-, or parasite-infected cells and tumor cells in a targeted manner, even in the case of mutations. According to the invention, biologically active molecules are administered, said biologically active molecules including at least one protease inhibitor for at least one specific target protease of the virus-, bacteria-, or parasite-infected cells and/or tumor cells and at least one peptide-inhibited siRNA, PNA or RNA, the peptide bond of which is broken by the at least one target protease for the purpose of activating the peptide-inhibited siRNA, PNA or RNA. The molecules are used, for example, to influence the gene expression of diseased and infected organs or cells.

Abstract: The invention is directed to a ternary azeotrope-like mixture consisting essentially of effective amounts of 1,1,1,3,3-pentafluoropropane, 1-chloro-3,3,3-trifluoropropene, and hydrogen fluoride.

Abstract: Novel compositions comprising polymer solutions at various viscosities are provided. The polymer solutions are preferably fugitive, so as to avoid interfering with the properties of the nanomaterials after post-processing of the CNT-containing formulations. Additives, including acid generators, are added to the polymer solutions in order to allow the polymer carrier solutions to be degraded or decomposed at temperatures low enough to allow processing of commonly-used polymer film substrates. The invention further allows the carbon nanotube solutions to be screen printed or printed via inkjet.

Abstract: Provided are a dispersed solution of carbon nanotubes including carbon nanotubes, an organic solvent, a spacer, and a dispersant. The dispersed solution of the carbon nanotubes includes both the spacer reducing the van der Waals force of the carbon nanotubes and preventing the bundling of the carbon nanotubes and the dispersant maintaining the debundling and stability of the carbon nanotubes, thereby improving the dispersibility of the carbon nanotubes. The preparation method of the dispersed solution of the carbon nanotubes can easily produce a dispersed solution of carbon nanotubes without separately performing a chemical treatment.

Abstract: The object of the invention is a process and agents to remove metal contaminants from hydrocarbon fractions like those obtained as a product from the Fischer-Tropsch synthesis involving the use of suspended catalyst. As per the present invention, the feed hydrocarbon fraction is treated with a demetallizing agent, comprising at least one sulfur source and at least one basic compound, under anhydrous conditions. The metals to be removed are obtained in the form of precipitate that can be easily separated by means of a mechanical separation process such as filtration, for example.

Abstract: Paper coating compositions contain specific polyethers which are obtained by reacting a diglycidyl ether with a water soluble polyol containing at least one polyoxyethylene chain acting as deflocculants, water retention agents and gloss enhancers.

Abstract: The present invention provides for a composition comprising two or more feedstocks and an ionic liquid (IL). The present invention also provides for a method for treating feedstocks, comprising providing a composition of the present invention comprising two or more feedstocks and an ionic liquid (IL).

Abstract: There is provided a hydrogelator that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A hydrogelator comprising a lipid peptide represented by Formula (1): (where R1 represents an aliphatic group having 9 to 21 carbon atoms; R2, R3 and R4 independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atom(s) which may have a branched chain having 1 or 2 carbon atom(s), a phenylmethyl group or a —(CH2)n—X group, and at least one of R2, R3 and R4 represents a —(CH2)n—X group; n represents the number of 1 to 4; X represents an amino group, a guanidino group, a —CONH2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which may have 1 to 3 nitrogen atom(s)) or a salt thereof, and a hydrogel comprising the hydrogelator.

Abstract: The invention relates to a cellulose solution manufacturing method including: performing an ozonation treatment to bring a cellulose-containing material and ozone into contact with each other; and performing an alkali treatment to bring the obtained treated material and an alkali aqueous solution into contact with each other, thereby dissolving at least cellulose in the cellulose-containing material brought into contact with the ozone in the alkali aqueous solution. According to the invention, it is possible to provide a method of manufacturing a cellulose solution in which cellulose can be dissolved in a more simple manner, a method of manufacturing a cellulose precipitate in which cellulose can be recovered from the cellulose solution, and a method of saccharifying cellulose which uses the cellulose precipitate.

Abstract: An improved method of conducting the pre-soaking step involving pre-soaking the ligno-cellulosic biomass in a liquid (water) at a temperature in the range of between 100° C. to 150° C. prior to soaking at higher temperatures. This material can then be soaked and soaked liquid filtered by nano-filtration. When nano-filtration is used, the pre-soak temperature can be in the range of 10° C. to 150° C.

Abstract: Activated carbon is rendered more thermally stable by exposure to a non-halogenated additive, and optionally to a halogen and/or a halogen-containing compound. Such treated carbon is suitable for use in mitigating the content of hazardous substances in flue gases, especially flue gases having a temperature within the range of from about 100° C. to about 420° C.

Abstract: A composition is described including a first fluorinated hydrocarbon compound according to the formula: wherein R1, R2, R3, R4, and R5 are each independently H, F, Cl, Br, or I, n is 0, 1, 2, or 3, and each R? group is independently H, F, Cl, Br, or I, with the proviso that zero to three of R1, R2, R3, R4, and R5 are F; a second fluorinated hydrocarbon compound according to the formula: wherein m is 0 or 1, and R6, R7, and R8 are each independently H, F, Cl, Br, or I, with the proviso that one of R6, R7, and R8 is F; and a third fluorinated hydrocarbon compound according to the formula: wherein R9, R10, R11, R12 and R13 are each independently H, Cl, Br, or I.

Abstract: Polymers useful as catalysts in non-enzymatic saccharification processes are provided. Provided are also methods for hydrolyzing cellulosic materials into monosaccharides and/or oligosaccharides using these polymeric acid catalysts.

Abstract: Surfactants with polyether sulfonate structure, which have a propanonylsulfonic acid group as a head group, a process for preparing such surfactants and their use for tertiary mineral oil extraction.

Abstract: An antistatic adhesive composition, an adhesive film produced using the same, a method for producing the adhesive film, and a method of fabricating a liquid crystal display, the antistatic adhesive composition including 100 parts by weight of a (meth)acrylic adhesive resin, the resin having functional groups capable of bonding with a cross-linking agent, about 0.01 to about 15 parts by weight of a cross-linking agent, and about 0.1 to about 10 parts by weight of a quaternary ammonium salt, the quaternary ammonium salt being obtained by reacting an amine having two or more terminal hydroxyalkyl groups with one of an organic or inorganic acid.

Abstract: The invention provides gold-plated mesoporous silicate bodies comprising pores and at least one agent and methods of using those bodies.

Abstract: Provided are methods and compositions for the generation of broad size distributions of polynucleic acid fragments from larger polynucleic acids. The invention provides unbiased polynucleic acid fragments, i.e. fragments representative of all portions of the larger polynucleic acids. The methods are amendable to automation and are cost-effective. The methods comprise contacting the polynucleic acid sample with a reducing agent and a transition metal in a solvent to form a mixture. An exemplified reducing agent is sodium ascorbate, and an exemplified transition metal is copper.

Abstract: An ionic compound is represented by formula (1): AM(OY1)(OY2)(OY3)(OY4). A is a group 1 element. M is a group 13 element. Y1 is one selected from an oligoalkylene ether group, an oligoalkylene thioether group, and an oligoalkylene amino group and includes an electron donating group on carbon that is located in one of ?-? positions with respect to oxygen atom adjacent to M. Y2, Y3, and Y4 are the same each other or different from each other or cross-linked to each other. Y2, Y3, and Y4 are each any one of an alkyl group, an alkyl group with a fluorinated terminal, an aryl group, and one selected from the group consisting of an oligoalkylene ether group, an oligoalkylene thioether group, and an oligoalkylene amino group and including an electron donating group on carbon that is located in one of ?-? positions with respect to oxygen atom adjacent to M.

Abstract: The present invention relates to a novel dry concentrate for producing medical solutions, more particularly dialysis solutions, which comprises electrolyte components, buffer components and an osmotic agent, wherein the concentrate comprises magnesium carbonate instead of magnesium chloride. The use of magnesium carbonate as an electrolyte prevents the formation of slurries. By providing anhydrous glucose as an osmotic agent, and by optionally spatially separating this osmotic agent from other components, the occurrence of caking of the concentrate is additionally avoided. The occurrence of caking is further reduced by providing the buffer component sodium bicarbonate together with sodium chloride separate from all other components. The concentrate of the present invention is particularly suitable for use in multi-chamber container bag systems. The concentrate of the present invention exhibits good dissolution behaviour and improved storage stability.

Abstract: Disclosed herein is a way to produce a series of discrete sized slender, rigid oligoparaxylene molecules ranging from 1-5 nm in length. Molecules, based on 1-7, 9-11 paraxylene rings, have been synthesized as part of a homologous series of oligoparaxylenes (OPXs) with a view to providing a molecular tool box for the construction of nano architectures—such as spheres, cages, capsules, metal-organic frameworks (MOFs), metal-organic polyhedrons (MOPs) and covalent-organic frameworks (COFs), to name but a few—of well-defined sizes and shapes. Twisting between the planes of contiguous paraxylene rings is generated by the steric hindrance associated with the methyl groups and leads to the existence of soluble molecular gauge blocks without the need—at least in the case of the lower homologues—to introduce long aliphatic side chains onto the phenylene rings in the molecules.

Abstract: Use of a composition comprising a) at least one imidazolium salt of the formula I where R1 and R3 are each, independently of one another, an organic radical having from 1 to 20 carbon atoms, R2, R4 and R5 are each, independently of one another, an H atom or an organic radical having up to 20 carbon atoms and A? is an anion, and b) at least one carboxylate selected from among those of the formula IIa of the formula IIb and the formula IIc where the radicals R1 to R5 are as defined above, as operating material in industrial apparatuses.

Abstract: Magnetic particles capable of binding a target substance, which comprise a magnetic material and a matrix material, wherein the magnetic material is remanent upon exposure to a magnetic field and the matrix material has a surface comprising functional groups which promote disaggregation of the particles in the presence of a liquid phase.

Abstract: A dampening fluid useful in offset ink printing applications contains water and a surfactant whose structure can be altered. The alteration in structure aids in reducing accumulation of the surfactant on the surface of an imaging member. The surfactant can be decomposed, switched between cis-trans states, or polymerizable with ink that is subsequently placed on the surface.

Abstract: The present invention provides azeotrope-like compositions of cis-1,3,3,3-tetrafluoroprone (HFO-1234ze (Z)) with 1,1,1,3,3-pentafluoropropane (HFC-245fa) and uses thereof, including use in refrigerant compositions, refrigeration systems, blowing agent compositions, and aerosol propellants.

Abstract: Disclosed herein is a process for purifying aryl carboxylic acids, in particular terephthalic acid, wherein the impure acid is dissolved or dispersed in an ionic liquid and a non-solvent is added to precipitate the purified acid. The present disclosure further relates to compositions comprising terephthalic acid and one or more ionic liquids.

Abstract: An electrorheological fluid comprises a nanoparticle composition comprising a nanoparticle, uncoated or coated with a polymeric or metallic coating and covalently bonded to or coated on a surface of a polymeric or inorganic particle; and a dielectric fluid having a dielectric constant lower than that of the nanoparticle composition. A nanoparticle composition also comprises a carbon-based nanoparticle, covalently bonded to or coated on a surface of a conjugated polymer particle or inorganic particle, wherein the nanoparticle composition is a dielectric material.

Abstract: The invention relates to porous dielectric layers obtained from pore-forming precursors and from matrix precursors. According to the invention, the pore-forming precursors used are chosen form molecules of myrtenol, ethyl chrysanthemumate, jasmine, trimethylbenzene, their positional isomers and their substituted or hydrogenated derivatives. The dielectric constant of the layer obtained is less than or equal to 2.5, starting from matrix precursors having a dielectric constant of less than or equal to 4.

Abstract: The present invention provides compositions and methods for the genetic manipulation of Algal cells. The compositions and methods allow enhanced transfer of genetic material into Algal cells and the cloning and selection of genetically modified cells. Expression of proteins encoded by the genetic material will be enhanced by the methods and compositions of the invention.

Abstract: The present invention relates to a process for the production of an aqueous glucose solution from maize or maize kernels. The invention also relates to a glucose solution obtainable by this process, and to its use for the production of organic compounds. The process according to the invention comprises: a) fractionating dry milling of maize kernels, where the maize kernels are separated into a maize-starch-comprising endosperm fraction and a high-oil germ fraction and, if appropriate, a bran fraction; b) enzymatic liquefaction and saccharification of the maize starch in an aqueous suspension of the endosperm fraction, which gives an aqueous glucose solution comprising maize gluten; and c) depletion of the maize gluten and, if appropriate, any bran present from the aqueous glucose solution.

Abstract: A potassium fluoride dispersion essentially consisting of potassium fluoride and an aprotic organic solvent having a boiling point higher than that of methanol, which is obtainable by mixing a mixture containing potassium fluoride and 5 to 50 parts by weight of methanol per 1 part by weight of potassium fluoride with the aprotic organic solvent followed by concentrating the obtained mixture, and a process for producing a fluorine-containing organic compound comprising contacting an organic compound having at least one group capable of being substituted nucleophilically with a fluorine atom with the potassium fluoride dispersion.

Abstract: A method of manufacturing a carboxylic acid ester is described. Also described, is a method for manufacturing a carboxylic acid ester by reacting a carboxylic acid and an alcohol, wherein the reaction is performed in the presence of an excess of carboxylic acid.

Abstract: A method for preparing a radioactive tracer provided with a radioactive fluorine isotope, including providing a precursor of the radioactive tracer, comprising at least one leaving group completely or partially formed by a labelling entity, wherein said leaving group can be moved by a fluoride ion, providing a molecularly imprinted polymer dedicated to the molecular recognition of at least the aforementioned labelling entity, exposing the precursor to a radioactive fluoride ion source under conditions suitable for movement of the leaving group by a radioactive fluoride ion, placing the mixture resulting from step (iii) in contact with the molecularly imprinted polymer under conditions suitable for the recognition of the labelling entity, and obtaining a solution containing the radioactive tracer provided with a radioactive isotope of fluorine obtained at the end of step (iii).

Abstract: Methods are provided for producing cells within a lineage (lineage restricted cells) from post-mitotic differentiated cells of the same lineage ex vivo and in vivo, and for treating a subject in need of tissue regeneration therapy by employing these lineage-restricted cells. In addition, the production of lineage restricted cells from postmitotic tissues derived from patients with diseases allows for a characterization of pathways that have gone awry in these diseases and for screening of drugs that will ameliorate or correct the defects as a means of novel drug discovery. Also provided are kits for performing these methods.

Abstract: Disclosed are azeotropic and azeotrope-like mixtures of (Z)-1-chloro-3,3,3-trifluoropropene (1233zd(Z)) and hydrogen fluoride. Such compositions are useful as an intermediate in the production of 1233zd(Z). The latter compound is useful as a nontoxic, zero ozone depleting fluorocarbon useful as a solvent, blowing agent, refrigerant, cleaning agent, aerosol propellant, heat transfer medium, dielectric, fire extinguishing composition and power cycle working fluid.

Abstract: Continuous process for producing a chlorohydrin, wherein a polyhydroxylated aliphatic hydrocarbon, an ester of a polyhydroxylated aliphatic hydrocarbon or a mixture thereof is reacted with a chlorinating agent and an organic acid in a liquid reaction medium whose steady-state composition comprises the polyhydroxylated aliphatic hydrocarbon and esters of the polyhydroxylated aliphatic hydrocarbon whose sum content, expressed as moles of polyhydroxylated aliphatic hydrocarbon, is greater than 1.1 mol % and less than or equal to 30 mol %, the percentage being based on the organic part of the liquid reaction medium.

Abstract: The invention relates to a method for producing homogeneous solutions of metal complexes of general formula (2): [MaLxXn]Ym, where M is a metal from the group comprising Mn(II), Mn(III), Mn(IV), Fe(III), Fe(III) or Fe(IV), X is a coordinated compound selected from mono- bi- or tri-charged anions or neutral molecules which are able to coordinate with a metal mono- bi- or tri-dentate, Y is a non-coordinated counter-ion which ensures charge equalization of the complex, L is a ligand of general formula (1) or the protonized or de-protonized form thereof, and a, x, n, m, R, R1, R2, R3 and z are as specified in claim 1, in diols or polyols, the monoethers or mixtures of said substances. Said method is characterized in that a ligand of the formula (1) is reacted with an iron or manganese salt in a heterogeneous reaction in the diol or polyol, the monoethers or mixtures of these substances.

Abstract: The present invention provides an organic phase composition comprising: (a) a first solvent (S1) characterized by a water solubility of less than 10% and by at least one of (a1) having a polarity related component of Hoy's cohesion parameter (delta-P) between 5 and 10 MPa1/2 and (b1) having a Hydrogen bonding related component of Hoy's cohesion parameter (delta-H) between 5 and 20 MPa1/2; (b) a second solvent (S2) characterized by a water solubility of at least 30% and by at least one of (a2) having a delta-P greater than 8 MPa1/2 and (b2) having a delta-H greater than 12 MPa1/2; (c) water; (d) HCl; and (e) a carbohydrate.

Abstract: The present invention provides an organic phase composition comprising (f) a first solvent (S1) characterized by water solubility of less than 10% and by at least one of (a1) having a polarity related component of Hoy's cohesion parameter (delta-P) between 5 and 10 mPa1/2 and (b1) having a Hydrogen bonding related component of Hoy's cohesion parameter (delta-H) between 5 and 20 MPa1/2; (g) a second solvent (S2) characterized by water solubility of at least 30% and by at least one of (a2) having a delta-P greater than 8 MPa1/2 and (b2) having a delta-H greater than 12 MPa1/2; (h) water (i) HCl, and (j) a chloride salt.

Abstract: Provided is a composition comprising an alkali metal glycerate or an alkaline earth metal glycerate and glycerol, and a method for preparing the same. Also provided are methods for removing a fatty acid from a fatty acid-comprising glyceride or a fatty acid alkyl ester (deacidifying) or drying a glyceride or fatty acid alkyl ester, involving contacting a mixture of the fatty acid and the fatty acid-comprising glyceride or the fatty acid alkyl ester, or mixing the glyceride or fatty acid alkyl ester, with the composition.

Abstract: The present invention provides a method for preparing modified micronized particles, comprising the steps of carrying out co-precipitation in an aqueous solution at a temperature between the freezing point and the boiling point of the reaction mother liquid to produce a mixed precipitate of micronized particles or precursors thereof and an inorganic precipitate. The method effectively solves the conflict between micronization and surface modification of particles, and resolves the problem that it is difficult to separate micronized particles from the reaction mother liquid.

Abstract: A process for pretreatment of a biomass material, comprising subjecting a biomass material to a biphasic mixture of water and supercritical CO2 at a temperature in the range of 150° C. to 250° C. under high pressure for a time of from 10 seconds to 100 minutes. In particular embodiments, the process is performed as a two-stage temperature process wherein an initial short high-temperature stage is conducted at a temperature of at least 200° C. for up to 20 minutes and a subsequent longer low-temperature stage is conducted at a temperature of at least 140° C. and up to 190° C. for 10-120 minutes.

Abstract: A method for obtaining cochineal wax is provided which comprises (a) harvesting cochineal insects from an artificial medium inoculated with the insects; (b) extracting cochineal wax from the insects with a liquid medium; and (c) isolating cochineal wax from the liquid medium.

Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce ethanol and/or butanol, e.g., by fermentation.

Abstract: A method of reducing volatile organic compounds produced during a fermentation process includes (a) producing a volatile organic compound during a fermentation process, (b) generating ClO2 gas, (c) dissolving the ClO2 gas to form a ClO2 solution, and (d) introducing an aqueous ClO2 solution into said volatile organic compound wherein introducing said ClO2 solution reduces concentration of said volatile organic compounds. Another method includes (a) producing a volatile organic compound during a fermentation process, and (b) introducing ClO2 having an efficiency as ClO2 of at least about 90% into the volatile organic compound wherein introducing said ClO2 solution reduces concentration of said volatile organic compounds. An apparatus for treating volatile organic compounds produced during a fermentation process comprises a ClO2 generator fluidly connected to a batch tank, fluidly connected to a volatile organic compound producing fermentation vessel.

Abstract: A method of preparing a surface-treated cellulosic substrate, the method comprising applying a surface treatment composition to a cellulosic substrate, the composition being prepared by a method comprising the steps of introducing a source of boron, a crosslinking di-aldehyde, and a blocking agent to form a crosslinking composition; introducing the crosslinking solution with starch and optionally pigments and/or optionally polymeric particles to form the composition.

Abstract: A spinning solution composition which provides regenerated silk fiber that exhibits a strength and elongation close to those of natural silk fiber, is rapidly degradable in vivo, and can be caused to have ability to gradually release a drug to prevent inflammation; a process for producing such regenerated silk fiber by use of the composition; and regenerated silk fiber obtained through the process.

Abstract: The present invention provides a system for the sterilization of natural products without negatively effecting the properties of the system having a sterilization chamber; a sample area within the sterilization chamber to hold one or more steam permeable containers; a heater source connected to the sterilization chamber for heating the sterilization chamber to a predetermined temperature; a heater control unit connected to the heater source for controlling the predetermined temperature; a pressure source connected to the sterilization chamber for pressurizing the sterilization chamber to a predetermined pressure; a pressure control unit connected to the pressure source for controlling the predetermined pressure; a steam aperture for supplying steam to the sterilization chamber; a steam control unit connected to the temperature and duration of the steam; and an interface connected to the heater control unit, pressure control unit, and steam control unit.

Abstract: The invention provides amphiphiles for manipulating membrane proteins. The amphiphiles can feature carbohydrate-derived hydrophilic groups and branchpoints in the hydrophilic moiety and/or in a lipophilic moiety. Such amphiphiles are useful as detergents for solubilization and stabilization of membrane proteins, including photosynthetic protein superassemblies obtained from bacterial membranes.

Abstract: There is provided a mixture having a freezing point of up to 100° C. formed by a process comprising the step of contacting: (A) from 1 to 2 equivalents of a compound of formula (I) AlX3 (I) wherein each X independently represents Cl, Br or F; with (B) 1 equivalent of a compound of formula (II) R1—C(O)—N(R2)(R3) (II) wherein R1 to R3 have meanings given in the description. There is also provided further mixtures containing additional components, as well as methods of using the mixtures in various applications, such as for the electroreduction of the mixtures to produce aluminium metal.