Radioactive Compositions Patents (Class 252/625)
  • Patent number: 5093302
    Abstract: A radioactive catalyst is disclosed which comprises a fine particle of semiconductor and a high radioactive platinum group element deposited on the particle of semiconductor. The radioactive catalyst serves as a source of radiation and also as a catalyst for oxidation-reduction reaction. By bringing the radioactive catalyst into contact with water, the water is decomposed by the oxidation-reduction reaction to produce hydrogen and oxygen.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: March 3, 1992
    Assignee: Doryokuro Kakunenryo Kaihatsu Jigyodan
    Inventors: Nobuyuki Sasao, Yukio Wada
  • Patent number: 5093105
    Abstract: Benzalkonium chloride and benzethonium chloride are each useful in radiopharmaceutical preparations as bacteriostatic agents which are compatible with anti-oxidants.
    Type: Grant
    Filed: April 9, 1991
    Date of Patent: March 3, 1992
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Richard J. Flanagan, Daniel Tartaglia
  • Patent number: 5085848
    Abstract: A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.
    Type: Grant
    Filed: April 16, 1991
    Date of Patent: February 4, 1992
    Assignee: The United States of America as Represented by the United States Department of Energy
    Inventors: Robert W. Atcher, John J. Hines
  • Patent number: 5064633
    Abstract: Particle emitting radionuclides, e.g. X-90, have been complexed with certain macrocyclic aminophosphonic acids wherein the nitrogen and phosphorus are interconnected by an alkylene group or substituted alkylene group. These complexes have been found useful in compositions and formulations for the therapeutic treatment of calcific tumors and the relief of bone pain in animals.
    Type: Grant
    Filed: December 19, 1989
    Date of Patent: November 12, 1991
    Assignee: The Dow Chemical Company
    Inventors: Jaime Simon, David A. Wilson, Joseph R. Garlich, David E. Troutner
  • Patent number: 5061475
    Abstract: An aggregate suspension containing holmium-166 hydroxide and a carrier (such as a particulate ferric hydroxide) is injected into a patient's anesthetized joint (such as a knee joint or hip joint) for the treatment of inflamed synovial tissues such as present in arthritis, especially rheumatoid arthritis. The aggregate suspension is in a range of particle sizes from 1 to 40 microns. The holmium-166-containing suspension treats the synovial tissues, whereby radiation synovectomy takes place.
    Type: Grant
    Filed: June 28, 1989
    Date of Patent: October 29, 1991
    Assignee: Cadema Medical Products, Inc.
    Inventors: Ephraim Lieberman, Maurice E. Bordoni, Alfred K. Thornton
  • Patent number: 5030441
    Abstract: A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: July 9, 1991
    Assignee: The United State of America as represented by the United States Department of Energy
    Inventors: Robert W. Atcher, John J. Hines
  • Patent number: 4997596
    Abstract: The disclosed invention consists of a ceramic form of fuel for a nuclear reactor comprising an oxide of a fissionable element and containing therein a consumable neutron absorbing agent. The ceramic fissionable fuel product provides longer fuel performance in nuclear reactor service.
    Type: Grant
    Filed: September 18, 1989
    Date of Patent: March 5, 1991
    Assignee: General Electric Company
    Inventors: Richard A. Proebstle, Mickey O. Marlowe, Anthony P. Reese
  • Patent number: 4976950
    Abstract: The invention concerns a method for suppressing bone marrow which comprises administering to a mammal at least one bone marrow suppressing complex of a radionuclide selected from the group consisting of Samarium-153, Gadolinium-159, Holmium-166 and Yttrium-90 and at least one macrocyclic aminophosphonic acid ligand containing the 1,4,7,10-tetraazacyclododecane moiety, or a physiologically acceptable salt thereof. Suitable compositions for use in this method are also provided.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: December 11, 1990
    Assignee: The Dow Chemical Company
    Inventors: Jaime Simon, Joseph R. Garlich, David A. Wilson, Kenneth McMillan
  • Patent number: 4971729
    Abstract: An ion exchange material comprises an oxide of a first element selected from elements of Groups IVa, IVb, Va, Vb, VIa, VIb, VIIa, or lanthanide or actinide series of the Periodic Table, in combination with an oxide of at least one different element selected from elements of the afore-mentioned groups of the Periodic Table so as to form a composite material. For example, a composite ion exchange material may comprise silicon dioxide and manganese dioxide. By selecting the appropriate oxides a composite ion exchange material can be prepared which has greater mechanical and/or chemical stability than an individual oxide of the composite material.
    Type: Grant
    Filed: January 4, 1990
    Date of Patent: November 20, 1990
    Assignee: British Nuclear Fuels plc
    Inventor: David A. White
  • Patent number: 4959181
    Abstract: Ion exchange performed by contacting a solution containing ions to be absorbed with a hydrous oxide of uranium in a suitable form. The hydrous oxide may be uranium dioxide or uranium hydroxide, and may be prepared by reducing a uranium species, precipitating the reduced species, and drying the precipitate to give the required hydrous oxide.
    Type: Grant
    Filed: March 20, 1989
    Date of Patent: September 25, 1990
    Assignee: British Nuclear Fuels PLC
    Inventors: David A. White, Paul Donson
  • Patent number: 4954293
    Abstract: Thorium and rare earth values are separated from a fluoride concentrate thereof, by decomposing such concentrate with aqueous sodium hydroxide under conditions such that the amount of sodium hydroxide is at least 1.4 times the stoichiometric amount and the initial sodium hydroxide/water ratio in the medium of decomposition ranges from 1 to 40% by weight, whereby a precipitate of thorium hydroxide and rare earth hydroxides is produced, together with a solution of sodium fluoride, and then separating the NaF solution therefrom.
    Type: Grant
    Filed: November 28, 1988
    Date of Patent: September 4, 1990
    Assignee: Rhone-Poulenc Chimie
    Inventors: Francinet Cailly, Frederic Fabre
  • Patent number: 4938798
    Abstract: A high melting metal silicide sputtering target which comprises a fine texture whose stoichiometric composition grains of MSi.sub.2, where M represents a high melting metal, have a maximum grain size of 20 .mu.m, whose free silicon grains have a maximum grain size of 50 .mu.m and whose oxygen content is not more than 200 ppm and has a density ratio to the theoretical density of 99% or more has good film characteristics including the reduction in the number of grains formed on the sputtered film and is useful as an electrode material or a wiring material in semi-conductor devices.
    Type: Grant
    Filed: March 7, 1988
    Date of Patent: July 3, 1990
    Assignee: Hitachi Metals, Ltd.
    Inventors: Yoshitaka Chiba, Noriyoshi Hirao, Toru Sugihara, Kenji Hasegawa
  • Patent number: 4915932
    Abstract: A formulation is provided for the treatment of synovial inflammation, the formulation consisting of dysprosium-165 hydroxide macroaggregates or yttrium-90 hydroxide macroaggregates, wherein the formulation is substantially devoid of other co-precipitating agents in particular, ferric hydroxide. A method of treatment of synovial inflammation is also provided in which the method comprises adminstering an intra-articular injection of the above formulation. Preferably the above formulation is in the form of a isotonic apyrogenic injectable solution.
    Type: Grant
    Filed: October 13, 1988
    Date of Patent: April 10, 1990
    Assignee: Australian Nuclear Science & Technology Organisation
    Inventors: Ashley B. McLaren, Eric L. Hetherington, Desmond J. Maddalena
  • Patent number: 4889707
    Abstract: Radioactive microspheres for radiation synovectomy of arithmetic joints in a mammal comprise a biodegradable glass material and a beta radiation emitting radioisotope chemically dissolved in and distributed substantially uniformly throughout the glass material. The biodegradable glass material may be lithium silicate, lithium aluminosilicate, lithium aluminoborate, lithium germanate, lithium aluminogermanate, potassium silicate, potassium aluminosilicate, potassium, aluminoborate, potassium germanate or potassium aluminogermanate and the beta radiation emitting radioisotope may be samarium-153, holmium-166, erbium-169, dysprosium-165, rhenium-186, rhenium-188 or yttrium-90. Methods for preparing such microspheres and for carrying out radiation synovectomy of arthritic joints utilizing such microspheres are also disclosed.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: December 26, 1989
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, Gary J. Ehrhardt
  • Patent number: 4885151
    Abstract: A diagnostic aid for the scintigraphic visualization of malignant tumors which contains a radionuclide which is bonded by means of a complex-forming agent to the substance obtained by the enzymatic processing of murein with enzyme consisting essentially of hen's eggwhite lysozyme.
    Type: Grant
    Filed: June 25, 1987
    Date of Patent: December 5, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erich Oberhausen, Ludwig Kuhlmann, Gerhard Seibert, Axel Steinstrasser, Hans-Joachim Schroth, Karl-Heinz Bremer
  • Patent number: 4882142
    Abstract: The invention concerns a method for suppressing bone marrow which comprises administering to a mammal at least one bone marrow suppressing complex of a radionuclide selected from the group consisting of Samarium-153, Gadolinium-159, and Holmium-166 and 1,4,7,10-tetraazacyclododecanetetramethylenephosphonic acid a physiologically acceptable salt thereof. Suitable compositions for use in this method are also provided.
    Type: Grant
    Filed: December 19, 1988
    Date of Patent: November 21, 1989
    Assignee: The Dow Chemical Company
    Inventors: Jaime Simon, Joseph R. Garlich, David A. Wilson, Kenneth McMillan
  • Patent number: 4857234
    Abstract: A partitioning radioactive tracer material is prepared by reacting an alkali-metal salt of radioactive iodine with chloroethanol in the presence of activated carbon.
    Type: Grant
    Filed: March 31, 1988
    Date of Patent: August 15, 1989
    Assignee: Conoco Inc.
    Inventor: Preston L. Gant
  • Patent number: 4816187
    Abstract: A fugitive binder composition for compression molding uranium dioxide nuclear fuel comprising the reaction product of a strongly alkali water solution of a diamine and oxalate ions with uranium oxide which is free of carbonates and carbamates, and having the formula:[.sup.+ NH.sub.3 (CH.sub.2).sub.2 NH.sub.3.sup.+ ][UO.sub.2 (C.sub.2 O.sub.4).sub.2 (H.sub.2 O).sub.2 ][.sup.+ NH.sub.3 (CH.sub.2).sub.2 NH.sub.3.sup.+ ].
    Type: Grant
    Filed: March 5, 1987
    Date of Patent: March 28, 1989
    Assignee: General Electric Company
    Inventors: Richard I. Larson, Richard P. Ringle
  • Patent number: 4789501
    Abstract: A radioactive microsphere for radiation therapy of a mammal comprising a biologically compatible glass material containing a beta or gamma emitting radioisotope distributed substantially uniformly throughout the glass. Advantageously, the radioisotope is produced by irradiation of the microsphere.
    Type: Grant
    Filed: November 19, 1984
    Date of Patent: December 6, 1988
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, Gary J. Ehrhardt
  • Patent number: 4772429
    Abstract: The invention relates to a process for the extraction of uranium (VI) and/or plutonium (IV) present in an aqueous solution by means of N,N-dialkylamides.These N,N-dialkylamides are in accordance with formula: ##STR1## in which R.sup.1 is a straight or branched alkyl radical with 2 to 12 carbon atoms, R.sup.2 and R.sup.4, which can be the same or different, are straight or branched alkyl radicals with 2 to 6 carbon atoms, R.sup.3 and R.sup.5, which can be the same or different, are straight or branched alkyl radicals with 1 to 6 carbon atoms and a and b, which can be the same or different, are integers between 1 and 6.For example, it is possible to use N,N-di-(2-ethyl hexyl)-2,2-dimethyl butyramide, N,N-di-(2-ethyl hexyl)-hexanamide or N,N-di-(2-ethyl hexyl)-dodecanamide for simultaneously extracting uranium and plutonium, or for separating the uranium from the plutonium without reducing the latter.
    Type: Grant
    Filed: December 2, 1986
    Date of Patent: September 20, 1988
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Nicole Descouls, Jean-Claude Morisseau, Claude Musikas
  • Patent number: 4701225
    Abstract: The present invention relates to a process for the heat treatment of uranium alloy members.This process comprises at least one .gamma.-phase homogenization stage, followed by an induction heating stage and a hardening stage. The use of induction heating makes it possible to only heat the member and therefore modify the structure thereof at the surface. Thus, the hardness in the core and on the surface can optionally be adjusted by supplementary hardening and/or tempering stages.Application to the production of protective materials.
    Type: Grant
    Filed: September 16, 1986
    Date of Patent: October 20, 1987
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Jean-Michel Morey, Gilles Paradis
  • Patent number: 4454061
    Abstract: A new group of materials comprises intercalates of organometallic compounds in layered structures of water-insoluble salts comprised of a tetravalent metal cation and an acid phosphate, arsenate or vanadate anion. Related materials comprise intercalates of organometallic compounds in layered structures of uranyl and transuranyl phosphates, arsenates and vanadates. Intercalation hosts are represented either by the formula M(H.sub.1-y A.sub.y XO.sub.4).sub.2.nH.sub.2 O or by the formula H.sub.1-y A.sub.y TO.sub.2 XO.sub.4.nH.sub.
    Type: Grant
    Filed: May 26, 1982
    Date of Patent: June 12, 1984
    Assignee: Exxon Research and Engineering Co.
    Inventor: Jack W. Johnson
  • Patent number: 4437999
    Abstract: The method of feeding an insoluble organic solid material in the form of an organic resin or biological matter containing contaminating material such as radioactive waste from a nuclear facility or from treatment of animal or plant tissue in a laboratory or medical facility into a vessel containing water and to which ultraviolet light and ozone, preferably by sparging, are applied while the water is being agitated to distribute the ozone. The ozone oxidizes the organic resin or biological material, which disintegrates on oxidation substantially into water and carbon dioxide, leaving substantially no resin or biological material after treatment by the ultraviolet light and ozone for a prescribed period of time, and leaving the contaminant material as a precipitate or in solution in the remaining water or as an escaping gas, in any of which forms it can be readily separated from the water for disposal or further treatment.
    Type: Grant
    Filed: August 31, 1981
    Date of Patent: March 20, 1984
    Assignee: Gram Research & Development Co.
    Inventor: Sherman T. Mayne
  • Patent number: 4427645
    Abstract: The invention relates to a process for the automatic preparation of solutions from environmentally noxious substances in solvents whereby the noxious substance is brought on a receiver and by means of an airtight adapter and a feed connection into a hermetical sealed, storage bin, an exact quantity of the substance is dosed into a measuring and mixing vessel by means of a dosing screw after the solvent is dosed into this vessel, the substance is mixed and dissolved maintained at a certain temperature filtered and delivered to a storage vessel in an automatic sequence.
    Type: Grant
    Filed: December 8, 1980
    Date of Patent: January 24, 1984
    Assignee: AGFA-Gevaert Aktiengesellschaft
    Inventors: Hans Frenken, Josef Friedsam, Karl Voss
  • Patent number: 4330628
    Abstract: Alkali-resistant glass fibres, in the form of continuous-filament for use as reinforcement in cementitious products, or in the form of glass wool, are given enhanced alkali resistance by the incorporation of ThO.sub.2. The fibres are formed from a glass composition comprising, in weight percentages:______________________________________ SiO.sub.2 50 to 75% ThO.sub.2 + ZrO.sub.2 5 to 30% with ThO.sub.2 at least 0.4% R.sub.2 O 0 to 25% R'O 0 to 40% R.sub.2 O + R'O 10 to 40% Rare earth oxides 0 to 20% ______________________________________the content of ThO.sub.2 being at least 1% when the content of ZrO.sub.2 is less than 6% but not exceeding 9.5% when ZrO.sub.2 exceeds 8%, where R.sub.2 O represents Na.sub.2 O, K.sub.2 O or LiO.sub.2, with K.sub.2 O not exceeding 10% and Li.sub.2 O not exceeding 5% and R'O represents one or more of MgO, CaO, SrO, BaO, ZnO and MnO.
    Type: Grant
    Filed: March 17, 1980
    Date of Patent: May 18, 1982
    Assignee: Pilkington Brothers Limited
    Inventors: David R. Cockram, Kenneth M. Fyles