Abstract: Grignard reagents of halo-substituted conjugated dienes are prepared by reaction of 1- or 2-halo-substituted conjugated diene with magnesium metal employing a metal halide/saturated aliphatic halide catalyst system. The Grignard reagent can be employed in the preparation of hydroxy-substituted conjugated dienes and hydroxy-substituted allenes. Adjustment of the molar ratio of the metal halide to the halo-substituted conjugated diene permits favoring of hydroxy-substituted conjugated dienes or hydroxy-substituted allenes in the diene products.

Abstract: Grignard reagent is produced continuously in a reactor vessel, overflowing into a holding vessel from which the product is continuously removed; the reaction proceeds in the presence of an excess of magnesium constantly maintained, and a portion of the reacting mixture is withdrawn, circulated to a heat exchanger and returned to the reactor vessel.

Abstract: Hexyn-3-ol-1 is prepared by the steps of (1) reaction of a methyl magnesium halide with propargyl chloride to form an ethylacetylene magnesium halide, (2) addition reaction of ethylene oxide to the ethylacetylene magnesium halide to form a halogen magnesium salt of hexyn-3-ol-1, and (3) hydrolysis of the halogeno magnesium salt of hexyn-3-ol-1.

Abstract: Organic solvents containing less than 0.2 atom percent of .sup.13 C and which preferably are at least partially deuterated are produced from .sup.13 C-depleted gaseous carbon compounds and are advantageously employed as solvents for .sup.13 C NMR spectroscopy.

Abstract: This application discloses methods of preparing .alpha.,.alpha.-diloweralkyl substituted benzylamines by the catalytic hydrogenation of the corresponding .alpha.,.alpha.-dialkyl-4-(phenyl-ethynyl)-benzylamine. The produced .alpha.,.alpha.-diloweralkylamines are converted to the corresponding N-alkyl and N,N-dialkyl derivatives thereof. The amines and their alkylated derivatives are useful as antiarrhythmics.

Abstract: Tricyclo[4.2.1.0.sup.2,5 ]non-7-enes wherein the 3 position is substituted by a methylol group may be made by reacting a bicyclo[2.2.1]hepta-2,5-diene with a 2-alkenyl magnesium compound in a 1:1 ratio to yield a molecular addition product which is then oxidized and hydrolyzed to give the 3-methylol product. These substituted tricyclo[4.2.1.0.sup.2,5 ]non-7-enes are useful, inter alia, as intermediates for the manufacture of lubricating oil additives and various other useful products and they may be used for gas scrubbing applications and the like.

Abstract: Synthesis of, and intermediates for, trans-4, cis-7 tridecadienyl acetate, attractant for the male potato tuberworm moth.

Abstract: 10,11-Dihydro-12-(N,N-disubstitutedaminomethyl)-5,10-methano-5H-dibenzo[a,d ]cycloheptenes are prepared by reacting the Grignard reagent of 10,11-dihydro-12-halo-5,10-methano-5H-dibenzo[a,d]cycloheptenes with alkyl ethers of N,N-disubstitutedaminomethyl alcohols. Some of the intermediates in this process are novel compounds.

Abstract: A process for the preparation of phosphine oxides or sulphides of the formula: ##EQU1## in which R is a linear or branched aliphatic radical containing 5-12 carbon atoms, aralkyl radical selected from the group consisting of lower alkyl of 2-3 carbon atoms substituted by a phenyl group or R is cyclohexyl and X is an oxygen or sulphur atom comprising reacting a halo-compound of the formula R--Hal, in which Hal is chlorine, bromine or iodine, with magnesium to form a Grignard derivative of the formula RMgHal, the reaction being carried out initially in a very small amount of diethyl ether and then in a solvent mixture containing a preponderant amount of an aliphatic or aromatic hydrocarbon, which is liquid at room temperature or triethylamine, adding phosphorus oxychloride or phosphorus sulphochloride to the reaction mixture containing the Grignard derivative, and isolating the phosphine oxide or phosphine sulphide formed by removing the solvent by steam stripping or steam distillation.