Abstract: Sampling apparatus made of a material such as plastic material and/or glass, a body of the material forming a cavity for receiving a liquid sample, the sampling apparatus comprising a gauging region which can be arranged in a focus region of a visual measuring device for determining the position of the sampling apparatus and/or of the cavity, and in which at least one reference marker is arranged which can be detected by means of the visual measuring device, wherein the reference marker is formed in an inner region of the body that is remote from the surface.

Abstract: A device configured for rotation about an axis of rotation to drive liquid flow within the device. The device includes a detection chamber having opposed first second ends and two optical features defining an optical path through the detection chamber, between the first and second ends. The detection chamber includes a first liquid inlet disposed at the first end on a first side of the optical path, a first liquid outlet disposed at the second end of the detection chamber on the first side of the optical path and a second liquid outlet disposed at the second end of the detection chamber on a second side of the optical path. The first side of the optical path is radially outwards of the second side of the optical path.

Abstract: A particle imaging apparatus comprises a flow path comprising a first flow path section, a second flow path section connected downstream of the first flow path section, and a third flow path section that is branched from the first flow path section, a particle detection unit comprising a light source and a light detector, a particle sorting unit configured to adjust a flow direction of the particle, and a particle imaging unit configured to take an image of a particle that flows in the second flow path section. The flow path is structured such that a cross-sectional area of the second flow path section is greater than a cross-sectional area of the first flow path section. The first flow path section and the second flow path section are disposed so as to be linearly aligned.

Abstract: A sample cell can be designed to minimize excess gas volume. Described features can be advantageous in reducing an amount of gas required to flow through the sample cell during spectroscopic measurements, and in reducing a time (e.g. a total volume of gas) required to flush the cell between sampling events. In some examples, contours of the inners surfaces of the sample cell that contact the contained gas can be shaped, dimensioned, etc. such that a maximum clearance distance is provided between the inner surfaces at one or more locations. Systems, methods, and articles, etc. are described.

Abstract: A diagnostic system performs disease diagnostic tests using at least an optical property modifying device and a mobile device. A user provides a biological sample from a patient to the optical property modifying device that reacts with a reagent in one or more reaction chambers of the device. The user captures one or more images of the one or more reaction chambers using an optical sensor of the mobile device. The diagnostic system can determine a quality level of the images based on factors such as skew, scale, focusing, shadowing, or white-balancing. Based on an analysis of the captured image, the diagnostic system can determine a test result of a disease diagnostic test for the patient. The diagnostic system may communicate the test result, as well as instructions for the disease diagnostic test, to the user via the mobile device.

Abstract: The present invention provides a microfluidic system, device, and kit for particle analysis. In one example, the device includes a fluid channel for spacing the particles, an excitation waveguide to guide an excitation beam from a source to the fluid channel, and an excitation lens to focus the excitation beam to a width less than the spacing of the particles in the fluid channel. The device also includes a detection lens to guide light transmitted from the channel along a number of paths, axial and scatter light waveguide to receive light guided by the detection lens, a detector to receive transmitted light from the waveguides and generate a detection signal, and a processor configured to receive the detection signal and determine characteristic features of each of the particles based on the detection signal.

Abstract: The present disclosure relates to a process for facilitating the identification of target chemicals which may be detected by means of an ion mobility spectrometer and a system for implementing the same. In an aspect of the disclosure, there is provided a process for determining the ratio of CI? to CI?.OOH reactant ion species formed in a pentachloroethane doped ion mobility spectrometer operating in negative mode, said process comprising: i) introducing a sample comprising or consisting essentially of isoflurane into a pentachloroethane doped ion mobility spectrometer; ii) collecting data relevant to the detection of two isoflurane monomer ions formed following reaction with CI? and CI?.OOH reactant ion species present in the pentachloroethane doped ion mobility spectrometer; and iii) determining the ratio of CI? to CI?.OOH reactant ion species formed in the pentachloroethane doped ion mobility spectrometer based on an evaluation of the data collected.

Abstract: A spectrometer includes a support having a bottom wall part in which a depression and a peripheral part are provided, and a side wall part, a light detection element supported by the side wall part while opposing the depression, and a dispersive part disposed on an inner surface of the depression. A length of the depression in a second direction in which a plurality of grating grooves included in the dispersive part is aligned is larger than a length of the depression in a third direction orthogonal to the second direction when viewed in a first direction in which the depression and the light detection element oppose each other. An area of the peripheral part adjacent to the depression in the second direction is larger than an area of the peripheral part adjacent to the depression in the third direction when viewed in the first direction.

Abstract: A fluid analysis cartridge includes a reference well including a macromolecular coloring reagent having an optical characteristic that varies according to a thickness of the reference well, and a test well including a test reagent having an optical characteristic that varies according to a concentration of a component of a fluid sample that reacts with the test reagent and a thickness of the test well.

Abstract: Provided is a white-cell type non-dispersive infrared gas sensor and more particularly, a non-dispersive infrared carbon dioxide gas sensor deposited with a hydrophobic thin film. To this end, in a carbon dioxide gas sensor for measuring a concentration of carbon dioxide included in gas, the gas sensor is a white-cell type, in the white-cell, first and second reflectors 120 and 130 are disposed to face a third reflector 140, a light source 110 is provided at one side of the third reflector 140 and a first detector 150 and a second detector 160 are provided at the other side. Further, a first hydrophobic thin film 122 may be deposited on the entire reflection surface of the first reflector 120, a second hydrophobic thin film 132 may be deposited on the entire reflection surface of the second reflector 130, and a third hydrophobic thin film 142 may be deposited on the entire reflection surface of the third reflector 140.

Abstract: An arrangement for the spectrometric measurement of products, such as cereals, oleaginous products, or derived products, includes a mechanism for selective adjustment of the position of a light beam in vertical and horizontal planes, and a selective adjustment device for ensuring that rays of the light beam are parallel.

Abstract: Cuvette, comprising a first flat plate (1) and a second flat plate (2), both of which in a closed state of the cuvette are positioned so as to be situated opposite parallel to each other and at which there is at least one transparent first measuring surface (1.1) and at least one transparent second measuring surface (2.1), which define in pairs a measuring space (3), in which a liquid sample solution having a drop volume can be held by means of its surface tension and capillary forces. At least the second measuring surface (2.1) of each one of the measuring spaces (3) is a stepped surface, which has at least two plane-parallel partial measuring surfaces (2.1.1, 2.1.2), which are connected to each other by means of a setting surface (2.1.0), so that the partial measuring surfaces (2.1.1, 2.1.2) exhibit different vertical distances (b1, b2) from the first measuring surface (1.1).

Abstract: The present invention relates to a flow cell (10) comprising a fluid inlet (16) and a fluid outlet (18) separated by a sample flow-through chamber (12) comprising at least one UV-transparent window (22?), wherein the at least one UV-transparent window (22?) is made of a polymer material and has been subjected to Gamma radiation sterilisation. In one aspect, the flow cell is combustible.

Abstract: The invention relates to a nozzle for flow cytometry, the housing of which is tapering towards an outlet and in which a feed tube is arranged for a core flow liquid, the outlet opening of which is arranged at a distance from the outlet of the housing. The outlet of the housing forms the outlet of the nozzle. The housing of the nozzle extends from its outlet, which is arranged at its first end to its opposite second end, and has an inlet for a sheath flow liquid connected with the internal volume. The nozzle is characterized in that in the housing a leading element that promotes the alignment of particles extends from both sides of the feed tube.

Abstract: Methods, apparatus, devices and systems for mixing and dispensing multi-component materials. The mixing and dispensing may be performed using a mobile, enclosed dispenser that can be used to supply a mixed multi-component material at the point of use. In some embodiments, the components to be mixed into the multi-component material may be supplied in cartridges.

Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.

Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.

Abstract: Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.

Abstract: The present invention is an optical measurement system for measuring a liquid sample within a well. The system comprises a light source configured to transmit light though the well, a detector configured to measure optical signals derived from the transmitted light, and a tunable optical element. The tunable optical element is positioned between the light source and the well. The tunable optical element is operable to shape the light to compensate for distortions induced by a surface of the liquid sample. The detector is preferably located below the well for receiving a forward scatter signal indicative of at least one characteristic of the particles within the liquid sample.

Abstract: A testing device and a testing method for an optical film are disclosed. The testing device includes a carrier having a cavity, wherein the cavity is an enclosed space; a test condition providing module disposed in the enclosed space; wherein the optical film is disposed in the enclosed space and the test condition providing module is configured for providing a test condition simulating a real environment in a liquid crystal display module for the optical film. The testing device for an optical film is configured for testing the optical film to be tested.

Abstract: A chuck, a system including a chuck and a method for making a semiconductor device are disclosed. In one embodiment the chuck includes a first conductive region configured to be capacitively coupled to a first RF power generator, a second conductive region configured to be capacitively coupled to a second RF power generator and an insulation region that electrically insulates the first conductive region from the second conductive region.

Abstract: A method and apparatus for analyzing solubility of asphaltenes of a hydrocarbon fluid sample involves a sequence of operations including: i) performing microfluidic mixing operations that form a mixture that includes the hydrocarbon fluid sample, a solvent that dissolves asphaltenes and a precipitant that precipitates asphaltenes; ii) using microfluidic processes that result in precipitation of asphaltenes from the mixture resulting from i); iii) performing microfluidic filtering operations that remove precipitated asphaltenes resulting from ii) and passes permeate; and iv) performing optical spectroscopy on the permeate resulting from iii). The operations of i)-iv) can be repeated over iterations that vary the amount of solvent relative to the precipitant in the mixture. These iterations can cause varying fractional precipitation of asphaltenes in each given iteration.

Abstract: A method is provided for testing a diffusely reflective liquid for color strength, said liquid comprising particles in a carrier medium, e.g. white emulsion paint based on titanium dioxide. The method comprises measuring in situ a lightness parameter of the liquid, of the carrier medium and of the liquid diluted with amounts of carrier medium; and determining from said measurements a dilution parameter indicating the amount of carrier medium needed to produce a predetermined reduction in the lightness parameter of the liquid, said dilution parameter providing an indication of color strength. The lightness parameter may be L* in the CIE L*, a*, b* color space, and the test may be carried out using a diffuse reflection probe (10) configured to direct light from said probe (10) into the liquid and configured to collect a portion of the light from the probe (10) diffusely reflected by the paint for determining the lightness parameter. The results may be used for process control e.g. in emulsion paint manufacture.

Abstract: An automatic analyzer cartridge spinnable around a rotational axis has a fluid chamber for receiving a fluid, an aliquoting chamber, a duct connecting the fluid chamber and the aliquoting chamber, a downstream fluidic element, a siphon for siphoning the fluid from the aliquoting chamber to the downstream fluidic element, a fluidic structure for processing a biological sample into the processed biological sample, and a measurement structure for enabling measurement of the processed biological sample. The siphon has a siphon entrance in the aliquoting chamber and a siphon exit in the downstream fluidic element, wherein the siphon has a bend, wherein the bend is the portion of the siphon closest to the rotational axis, wherein the siphon entrance starts at the bend, wherein the siphon entrance extends to a lower portion of the aliquoting chamber. This enables multiple aliquots of fluid to be removed from the aliquoting chamber by the siphon.

Abstract: Aspects of the present disclosure include methods for producing an output laser beam having two or more angularly deflected laser beams (e.g., for irradiating a sample in a flow stream) with a predetermined intensity profile. Systems for practicing the subject methods having a laser, an acousto-optic device, a radiofrequency generator and a controller for adjusting the amplitude of the radiofrequency drive signals to produce an output laser beam of angularly deflected laser beams with a predetermined intensity profile are also described.

Abstract: The present invention discloses an automatic fecal occult blood detector for detecting a sample kit, comprising: a feed passage and a discharging passage which are provided in parallel and convey a sample kit separately; a transfer platform configured between the feed passage and the discharging passage; a push rod configured to push the sample kit on the feed passage onto the discharging passage through the transfer platform; and an image capturing device provided on one side of the discharging passage to acquire the color band information presented on a test strip. In the present invention, the parallel arrangement of the feed passage and the discharging passage shortens the whole length of the automatic detector, meeting the requirement that the color band information of the test strip is automatically acquired after the sample kit is left in the device a certain time.

Abstract: A flow cell including a flow cell bod having a flow path formed therein; an optically transmissive member disposed at a part wherein light from the light source is incident into, or emitted from, the flow path; a shock absorbing member that is disposed between the optically transmissive member and the cell body; an elastic member, made from a metal material, for pressing the optically transmissive member toward the cell body side; and a fastening tool, attached to the cell body, for positioning the elastic member.

Abstract: A method of testing an electrode paste for producing an electrode for a secondary battery includes preparing an electrode paste obtained by kneading at least active material particles and water dispersible binder particles in an aqueous solvent; performing centrifugation on the electrode paste and collecting a supernatant containing the binder particles, and a free active material; and measuring an absorbance of the supernatant at an evaluation wavelength by using a spectrophotometer, wherein the evaluation wavelength is determined based on a relationship between an average particle size of the binder particles and the absorbance of the supernatant such that a proportion of an absorbance resulting from the binder particles in the absorbance of the supernatant becomes equal to or less than 30%, the relationship being determined in advance; and determining a quality of the electrode paste, based on the absorbance of the supernatant at the evaluation wavelength.

Abstract: Described are systems, devices, and methods which related to various aspects of assays for detecting and/or determining a measure of the concentration of analyte molecules or particles in a sample fluid. In some cases, the systems employ an assay consumable comprising a plurality of assay sites. The systems, devices, and/or methods, in some cases, are automated. In some cases, the systems, devices, and/or methods relate to inserting a plurality of beads into assay sites, sealing assay sites, imaging assay sites, or the like.

Abstract: A specimen collection cup has a container. The container has a wall and a floor and is configured for receiving and retaining a specimen. A section of the wall is transparent. Further, the container has a tab coupled to an inside surface of the wall that creates a slot for receiving a test card having a reagent pad affixed thereto. The tab is coupled to the inside surface of the wall such that when the test card is inserted in the slot indicia on the test card is aligned with the transparent section.

Abstract: According to one embodiment, an automatic analyzer includes a magnetic field generator, a photometric unit, a measurement unit, and a decision unit. The magnetic field generator causes magnetic separation in a reaction liquid stored in a cuvette by magnetic particles. The photometric unit includes a light source unit configured to generate light, and a detection unit configured to detect the light generated by the light source unit and generate an output signal corresponding to the detected light. The measurement unit measures a measurement item based on the output signal. The decision unit decides the use range of the output signal to be used to measure the measurement item in accordance with spatial unevenness of the magnetic separation by the magnetic field generator.

Abstract: The present application is directed to a process for calibrating a detection apparatus, especially an ion mobility spectrometer, using isoflurane (CAS Reg. No. 26675-46-7) as a chemical standard whereby calibrating the detection apparatus for a known target chemical is based on an evaluation of the experimental data collected for the negative isoflurane monomer ion against the experimental data collected for the negative isoflurane dimer ion.

Abstract: An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate reduced sample read time and rapid reading of multiple light wavelengths.

Abstract: An apparatus for detecting macromolecules in a biological fluid is discloses which includes a first substrate and a second substrate. The first substrate includes a plurality of sampling apertures, at least some of which have different diameters. The sampling apertures are configured to screen and isolate the macromolecules in the biological fluid. The second substrate is stacked with the first substrate and includes a plurality of detectors vertically corresponding in position to the sampling apertures. Each of the detectors is configured to detect whether one of the macromolecules is present in a corresponding one of the sampling apertures and produce a detection output signal. A method for detecting macromolecules in a biological fluid is also disclosed. The apparatus has high integration and simple manufacturability, while the method is easy to use.

Abstract: A spectrometer includes a light detection element provided with a light passing part and a light detection part, a support fixed to the light detection element such that a space is formed between the light passing part and the light detection part, a first reflection part provided in the support and configured to reflect light passing through the light passing part in the space, a second reflection part provided in the light detection element and configured to reflect the light reflected by the first reflection part in the space, and a dispersive part provided in the support and configured to disperse and reflect the light reflected by the second reflection part to the light detection part in the space.

Abstract: An analytical laboratory system and method for processing samples is disclosed. The system includes a manager unit, as well as an aliquotter unit and a centrifuge unit.

Abstract: An apparatus for measuring a deposition rate includes a light source unit in a deposition region between a deposition source and a substrate in a vacuum chamber, the light source unit emits a monochromatic light toward a deposition material released from the deposition source, a photosensor unit that measures at least one of light absorption, scattering, and emission in the deposition region when light emitted from the light source unit passes through the deposition region, and a multi-pass forming unit defining a multi-pass path between the light source unit and the photosensor unit.

Abstract: A particle sensor is provided. The particle sensor includes a light projector that projects light to a detection area. A light receiver receives scattered light. The scattered light is light from the light projector that has been scattered by particles in the detection area. A first support supports the light receiver. A second support supports the light projector and has a linear expansion coefficient different from a linear expansion coefficient of the first support. The first support includes a first placement region in which the light receiver is disposed and a second placement region in which the second support is disposed. The first placement region and the second placement region are located at different distances from at least one of an optical axis of the light projector and an optical axis of the light receiver.

Abstract: Provided is an optical analyzer for performing a feedback control on the amount of light emitted from an LED as a light source, in which the configuration of an optical system is made simple and the degree of freedom in optical system arrangement is secured. An optical member 2 for focusing most of light while discharging part of the light as unfocused light is provided on an optical path from a light casting unit 1 to a sample cell 3. The optical member 2 can be achieved with a simple configuration, for example, two ball lenses spaced apart by a predetermined distance from each other. The light focused by the optical member 2 is cast as measurement light into the sample cell 3. Meanwhile, a second photodetector 5 is arranged at a position where the unfocused light reaches.

Abstract: A detection plate includes a track region having a bottom surface having a groove provided therein, and a well apart from the track region. The well has a bottom surface. The bottom surfaces of the track region and the well are disposed substantially on a plane. This detection plate detects a specimen rapidly and highly accurately with a simple structure.

Abstract: An automatic analyzer cartridge, spinnable around a rotational axis, has aliquoting and metering chambers, a connecting duct there between, and a vent connected to the metering chamber and nearer to the rotational axis than the metering chamber. The metering chamber has side walls that taper away from a central region. Capillary action next to the side walls is greater than in the central region. A circular arc about the rotational axis passes through a duct entrance in the aliquoting chamber and a duct exit in the metering chamber. The cartridge has a downstream fluidic element which is part of a fluidic structure for processing a biological sample into the processed biological sample. A valve connects the metering chamber to the fluidic element, which is fluidically connected to the fluidic structure. The fluidic structure receives the biological sample and has a measurement structure for enabling measurement of the processed biological sample.

Abstract: Disclosed is a sample analyzer configured to analyze a concentration of a target material contained in a sample based on a value representing a slope of a regression line which is based on data values included in an interval from a start point to an endpoint. The start point is detected by a predetermined method and the endpoint is detected by a predetermined method.

Abstract: An optical sensor may have multiple detection channels to detect different characteristics of a fluid. For example, an optical sensor used in industrial cleaning and sanitizing applications may have multiple detection channels to detect when a system is both clean and properly sanitized. In one example, an optical sensor includes an optical emitter that directs light into a fluid, a first optical detector that detects light transmitted through the fluid, a second optical detector that detects light scattered by the fluid, and a third optical detector that detects fluorescent emissions emitted by the fluid. The optical emitter and optical detectors can be positioned around an optical analysis area. The optical sensor may include filters that control the characteristics of light detected by each of the optical detectors.

Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.

Abstract: An optical blood monitoring system and corresponding method avoid the need to obtain a precise intensity value of the light impinging upon the measured blood layer during the analysis. The system is operated to determine at least two optical measurements through blood layers of different thickness but otherwise substantially identical systems. Due to the equivalence of the systems, the two measurements can be compared so that the bulk extinction coefficient of the blood can be calculated based only on the known blood layer thicknesses and the two measurements. Reliable measurements of various blood parameters can thereby be determined without certain calibration steps.

Abstract: A display is provided for an automatic analyzer to display statistics such as measurement results. A width of a display in a window that displays statistics may be adjusted and the amount of information to be displayed on the display is changed according to a level of detail of the information which the operator wants to confirm. Sample information, measurement results, and detailed information related to the measurement results are simultaneously displayed without a subwindow being displayed in overlapped form in the limited display area.

Abstract: A socket includes a first base member that includes a module mount unit allowing a module including an imaging device and an object to be placed thereon and an electric connector that electrically connects the imaging device to an external apparatus, a second base member having an opening, and an engagement unit that causes the first base member to be engaged with the second base member under a condition that the module placed on the module mount unit is sandwiched by the first and second base members. When the first base member is engaged with the second base member by the engagement unit under a condition that the module placed on the module mount unit is sandwiched by the first base member and the second base member, the electric connector is electrically connected to the imaging device, and the object receives illumination light from a light source through the opening.

Abstract: Systems, including apparatus and methods, for the microfluidic manipulation, dispensing, and/or sorting of particles, such as cells and/or beads. The systems may include a shaped focusing chamber and/or a branched diverting mechanism.

Abstract: A pressure adjusting device includes a housing with a cylinder. A piston moves within the cylinder in an axial direction. A pulse motor is fixed to the housing. A switch provided on a surface of the cylinder is actuated by movement of the piston in the cylinder in the axial direction. The switch includes a fixed contact point and a moveable contact point. The piston presses the movable contact point to abut against the fixed contact point when the piston moves from a position other than the initial position to the initial position so that the movable contact point electrically contacts the fixed contact point.

Abstract: In some examples, an image sensor system comprises a source module including a source housing having a source window and a source shielding member, the source module to emit a detection signal through the source window. the source shielding member surrounding the source window and extending in an outward direction from the source window. The image sensor system further comprises a detection module including a detection housing having a detection window and a detection shielding member, the detection module spaced apart from the source module and to detect the detection signal emitted from the source module and passed through the detection window, the detection shielding member surrounding the detection window and extending in an outward direction from the detection window.