Abstract: Provided is a spectrophotometric device including a base plate including a first surface to accommodate a sample thereon, a rotatable plate including a second surface corresponding to and spaced a certain distance apart from the first surface, a test beam radiator connected to the first surface through a first beam guide to radiate a test beam to the sample accommodated on a beam path between the first and second surfaces, a spectrophotometer connected to the second surface through a second beam guide to analyze spectroscopic properties of the sample by analyzing a characteristic beam having passed through the sample accommodated on the beam path, and a state determiner provided near the beam path to determine whether the sample accommodated between the first and second surfaces is in a state in which analysis of optical properties is enabled.

Abstract: A sample classification device including a carrier, a first detection module, and a sample pipeline is provided. The first detection module includes a first light-emitting device, a second light-emitting device, and a first optical sensing device. The first light emitting device is located on the carrier and used to emit light of a first wavelength. The second light emitting device is located on the carrier and used to emit light of a second wavelength. The first wavelength is different from the second wavelength. The first optical sensing device is located on the carrier and between the first light emitting device and the second light emitting device. The sample pipeline is located above the carrier and passes above the first optical sensing device.

Abstract: The disclosure provides a system, compositions, and methods for detecting ovarian cancer cells by photoacoustic flow cytometry.

Abstract: The present invention relates generally to a slope spectroscopy standards and methods of making slope spectroscopy standards, specifically standards and methods of developing standards specifically for variable pathlength (slope) measurements.

Abstract: A method performed by one or more devices is disclosed. The method includes obtaining a geometry information item representative of a spatial location of a plurality of points of a surface of a textile (52), determining at least one treatment parameter for treating the textile (52) at least partially based on a geometry information item, and outputting or triggering an output of the at least one treatment parameter.

Abstract: A structure of a flow cell assembly for a chromatography detector is used to generate a chromatograph of a sample, and includes a capillary extending in one direction, a housing that houses at least part of the capillary and a ferrule that holds the capillary in the housing. The capillary includes an inner tube formed of a material having a refractive index lower than that of water, and an outer tube formed of a material having strength higher than that of the material of the inner tube and has an outer diameter that is equal to or smaller than 5 mm. An outer peripheral surface of the inner tube and an inner peripheral surface of the outer tube adhere to each other, and a flow path through which a mobile phase including a sample flows is formed in the inner tube.

Abstract: An imaging system connected to an occupant monitoring system includes communications with an apparatus for measuring gas or airborne compound concentrations in a vehicle cabin. The apparatus includes a housing configured as a flow tube in fluid communication with ambient air in the vehicle cabin. A spectrometer is mounted within the housing and subject to ambient air flow through the housing, and the spectrometer is connected to a light source and receives reflected light from the air flow to detect by spectrum analysis the concentration of target gases and/or airborne compounds. The spectrometer identifies spectral changes in the light and reflected light within the ambient air flow. The spectrometer communicates with computerized vehicle control systems, and runs software stored to calculate the concentration of target gases and/or airborne compounds from the spectral changes.

Abstract: A concentration measuring device 100 comprises: a measurement cell 4 having a flow path, a light source 1, a photodetector 7 for detecting light emitted from the measurement cell, and an arithmetic circuit 8 for calculating light absorbance and concentration of a fluid to be measured on the basis of an output of the photodetector, the measurement cell includes a cell body, a window portion 3 fixed to the cell body so as to contact the flow path, and a reflective member 5 for reflecting light incident on the measurement cell through the window portion, the window portion is fixed to the cell body 40 by a window holding member 30 via a gasket 15, an annular sealing protrusion 15a is provided on a first surface of the gasket for supporting the window portion, and an annular sealing protrusion 42a is also provided on a support surface 42 of the cell body for supporting the second surface opposite to the first surface of the gasket.

Abstract: A thermal desorber assembly includes a housing and a desorption heater element mounted in the housing with a sample cavity defined between the desorption heater element and an inner wall of the housing. An outlet port is defined in the housing. A flow channel connects the sample cavity in fluid communication with the outlet port for conveying analytes from the sample cavity to the outlet port for introducing the analytes to a spectrometer.

Abstract: A photonic gas sensor and a method for producing a photonic gas sensor are disclosed. In an embodiment a photonic gas sensor includes a component housing with at least one cavity, a radiation-emitting semiconductor chip arranged in the cavity and configured to transmit electromagnetic radiation in a first wavelength range, a radiation-detecting semiconductor chip arranged in the cavity and configured to detect electromagnetic radiation in a second wavelength range and an active sensor element having a fluorescent dye configured to emit electromagnetic radiation in the second wavelength range upon being excited by electromagnetic radiation in the first wavelength range, wherein an intensity of the emitted electromagnetic radiation in the second wavelength range changes reversibly in presence of a gas to be detected.

Abstract: Aspects of the present disclosure include a particle sorting module having an opening that is configured for visualizing droplets of a deflected flow stream. Particle sorting modules according to certain embodiments include a housing having a proximal end, a distal end and a wall therebetween having an opening positioned in the wall that is configured for aligning the flow stream with one or more sample containers at the distal end. Systems and methods for aligning a flow stream with one or more sample containers and sorting particles of a sample (e.g., a biological sample) are also provided. Kits having one or more of the particle sorting modules suitable for coupling with a particle sorting system and for practicing the subject methods are also described.

Abstract: A liquid ejection device includes: a liquid ejection unit with an ejection port surface provided with an ejection port from which liquid is ejected and configured to eject the liquid onto a substrate at an ejection position; an image capturing mechanism configured to face the ejection port surface of the liquid ejection unit and to capture an image of the ejection port surface at a maintenance position different from the ejection position; and a lighting unit configured to irradiate the ejection port surface at multiple incidence angles with respect to the ejection port surface in an operation of capturing an image of the ejection port surface by the image capturing mechanism.

Abstract: A sensor arrangement for evaluating agricultural material, the arrangement comprising: a housing having an opening, the opening configured with a window transparent to electromagnetic waves; a detector arranged in the housing for detecting electromagnetic waves coming in through the window; a flexible seal element disposed between the window and the housing; and a compression member proximate at least one of the opening, the housing, the window and the seal element, the compression member configured to press the window against the seal element to seal off the housing.

Abstract: An object such as a cell colony may be picked from a plurality of objects by acquiring an image of the objects and an image of a pipette tip. The image of the objects is analyzed to select an object of interest. The selected object is associated with a coordinate position. Based on the coordinate position, the pipette tip is positioned over the selected object. An image of the pipette tip is then acquired and analyzed. The pipette tip is associated with a coordinate position. A positional error between the coordinate position of the selected object and the coordinate position of the pipette tip is determined. Based on the positional error, the pipette tip and/or a sample holder supporting the objects is moved to align the pipette tip over the selected object, by matching the coordinate position of the pipette tip with the coordinate position of the selected object.

Abstract: One or more homogenizing elements are employed in a flow through, multi-detector optical measurement system. The homogenizing elements correct for problems common to multi-detector flow-through systems such as peak tailing and non-uniform sample profile within the measurement cell. The homogenizing elements include coiled inlet tubing, a flow distributor near the inlet of the cell, and a flow distributor at the outlet of the cell. This homogenization of the sample mimics plug flow within the measurement cell and enables each detector to view the same sample composition in each individual corresponding viewed sample volume. This system is particularly beneficial when performing multiangle light scattering (MALS) measurements of narrow chromatographic peaks such as those produced by ultra-high pressure liquid chromatography (UHPLC).

Abstract: A microfluidic apparatus is provided. The microfluidic apparatus includes an electrochromic layer including a plurality of individually independently addressable regions; a microfluidic layer defining a microfluidic channel for allowing a microfluid to pass therethrough; and a plurality of photodetectors configured to detect light transmit through the microfluid.

Abstract: Disclosed is an optical flow cell (300?) comprising: a housing (910) forming; an enclosed and elongated fluid channel (920) arranged along a first axis (923); a first light guide (961) and a second light guide (962) generally concentrically arranged along a second axis (970) and on opposite side walls of the fluid channel, said first and second light guides having ends (961c,962c) removed in situ to provide a sensing gap (d).

Abstract: A mobile device based multi-analyte testing analyzer for use in medical diagnostic monitoring and screening, and a method of manufacturing the same are disclosed. A reflectance based, colorimetric test strip reader for use with a mobile device having a jack plug receiving socket, said test strip reader adapted for removably receiving a test strip having a test strip longitudinal axis, comprising a housing; a jack plug operably coupled to and extending from said housing and adapted for operable coupling with said jack plug receiving socket; a test strip adapter including structure defining a test strip receiving channel; a light source oriented within said housing for directing light toward said test strip receiving channel to illuminate a test strip arranged within said test strip adapter; and a light sensor oriented within said housing to sense light reflected from a test strip carried by said test strip receiving channel.

Abstract: A cassette for loading into a bay of an analyzer device, the cassette having a supply chamber for a test tape, an uptake chamber to receive used tape and a test zone between the chambers, where the tape is positioned at a test site for testing purposes, wherein the cassette includes a frame that extends across the test zone on a loading side of the tape, the frame being in a protective position relative to the tape, parallel to and aligned with the tape in the test zone, to protect the tape as the cassette is inserted into the bay of the analyzer device.

Abstract: Systems, devices and methods are provided for performing tissue removal and analysis based on the in-situ optical analysis of tissue and of liquid collected from the tissue region. In one example embodiment, a tissue removal and analysis probe includes an elongate tissue removal device, an optical fiber, and a fluid fillable conduit, where distal ends of the optical fiber and the conduit are in communication with an external region that is adjacent to a distal functional portion of the tissue removal device. The results of optical analysis one of both of external tissue and collected fluid may be employed to determine whether or not tissue removal is to be carried out. Various devices may be interfaced with the conduit for optical analysis of the collected fluid. In one example embodiment, the tissue removal device may be movable relative to the optical fiber and conduit.

Abstract: An apparatus (150) comprises a first detection chamber (130) for receiving microorganisms and configured to allow detection of the microorganisms via detection of scattered light from the first detection chamber (130); a medium (120) configured to permit passage of microorganisms from a sample (110) through the medium (120) into the first detection chamber (130); and at least one second detection chamber (140) configured to allow detection of the microorganisms via detection of scattered light from the at least one second detection chamber (140).

Abstract: Provided herein are coded fluid paths. Also provided herein are devices and systems containing one or more of the coded fluid paths. Also provided herein are methods of using the coded fluid paths, devices, and systems provided herein.

Abstract: This disclosure relates generally to a sampling device, and more particularly, a sampling device that facilitates spectroscopic measurements with a variable path length and the necessary software controlled algorithms and methods for such a device.

Abstract: Neutron dosimetry is performed using a water-based chemical dosimeter measurement of radiation-induced reduction of hexavalent Cr (VI) to trivalent Cr (III) in the presence of sodium formate at pH 9.2. Neutron absorbance material (Gd-157) increases the neutron interaction with the dosimeter. When a monoenergetic beam with 0.025 eV energy was used as a thermal neutron source 1 mol/dm3 of Gadolinium gave the best outcome while surrounding the dosimeter with 1 cm Gadolinium sheets. The dosimeter was giving acceptable readings when using thermal neutrons.

Abstract: A method of fabricating a variable diameter fiber includes providing a fiber optic cable, focusing a laser beam at a predetermined location inside the fiber optic cable, and creating a damage site at the predetermined location. The method also includes focusing the laser beam at a series of additional predetermined locations inside the fiber optic cable and creating a plurality of additional damage sites at the additional predetermined locations. The damage site and the additional damage sites define a variable diameter profile. The method further includes exposing the fiber optic cable to an etchant solution, preferentially etching the damage site and the plurality of additional damage sites, and separating a portion of the fiber optic cable to release the variable diameter fiber.

Abstract: A Raman probe provided includes a light source part configured to emit light on a sample, and further configured to adjust at least one of an incident angle of the light, a position of an emission point of the light, and a focal point of the light source part, a light collector configured to collect Raman scattered light from the sample, and further configured to adjust a field of view of Raman measurement and a focal point of the light collector, and a photodetector configured to receive the collected Raman scattered light, wherein the light source part comprises a reflection mirror configured to rotate to adjust the position of the emission point of the light.

Abstract: Apparatuses, methods, and software products for analyzing liquids dispensed from a chemical dispensing system. Beams of light having different wavelengths are passed through a liquid dispensed by the dispensing system. The intensity of each beam of light is measured after passing through the liquid. A transmission coefficient is determined by comparing the intensity of the beam of light to a calibration parameter obtained by passing the beam of light through an unadulterated diluent. The transmission coefficients for the beams of light are then compared to corresponding transmission coefficients obtained for one or more known reference solutions to determine one or more characteristics of the liquid being dispensed from the chemical dispensing system.

Abstract: Embodiments of the present invention include a device for removing energy from a beam of electromagnetic radiation. Typically, the device can be operatively coupled to a turbidity measuring device to remove energy generated by the turbidity measuring device. The device can include a block of material having one of a plurality of different shapes coated in an energy absorbing material. Generally, the device can include an angled or rounded energy absorbing surface where the beam of electromagnetic radiation can be directed. The angled or rounded energy absorbing surface can configured to deflect a portion of the beam of electromagnetic radiation to a second energy absorbing surface.

Abstract: Disclosed herein are seals for liquid-tight bonding of an optical window comprising a Bi—In alloy. Also disclosed are optical cells comprising the Bi—In alloy seals to provide a liquid-tight seal between a cell housing and a drilled optical window.

Abstract: A sample cell apparatus for use in spectroscopic determination of an analyte in a body fluid sample includes a first plate member made from an optically clear material and a second plate member made from an optically clear material and opposing the first plate member. A channel extending into a surface of the first plate member and an opposing surface of the second plate member houses a floating seal. The floating seal surrounds a fluid chamber that retains a sample of body fluid for optical measurement. The fluid chamber may be opened for flushing by separating the first plate member from the second plate member. During measurements the fluid chamber is closed to define a repeatable optical path-length therethrough by urging the first plate member against the second plate member without compressing the floating seal between the first plate member and the second plate member.

Abstract: Approximations to distinguish between X sperm and Y sperm are obtained by detecting light scattered into a pre-set angular range. The scattered light is scattered in turn by nuclei of sperm moving single-file in a sample container. The sperm are not modified prior to the light scattering and are not modified by the light scattering. Approximations are improved by at least a second detection of scattered light.

Abstract: The invention relates to a device (1) for the light spectroscopic analysis of a small amount of a liquid sample, comprising a receiving point (3) for receiving small amounts of the liquid sample, and light conductors (5, 6) which guide light of a light source to the sample and guide signal light from the sample in the direction of a detector, and is characterised in that an illumination source (7) is arranged below the receiving point (3), and a region (8) below the receiving point (3) which is permeable for the light of the illumination source (7), is provided such that the illumination light illuminates the receiving point (3).

Abstract: This disclosure relates generally to a sampling device, and more particularly, a sampling device that facilitates spectroscopic measurements with a variable path length and the necessary software controlled algorithms and methods for such a device.

Abstract: The present invention provides a heavy metal detecting device and the fabricating method thereof. The heavy metal detecting device includes a substrate and a nano-metal-particle array. The fabricating method of the heavy metal detecting device includes following steps of: (S1) preparing a substrate, cleaning the substrate with a first liquid, and drying the substrate with a first gas; (S2) soaking the substrate in a first solution; (S3) after soaking the substrate for a first period of time, cleaning and drying the substrate with the first liquid and the first gas respectively; (S4) soaking the substrate in a pre-synthesized nano-metal-particle solution; and (S5) after soaking the substrate for a second period of time, cleaning and drying the substrate with a second liquid and the first gas respectively. Compared to the prior arts, the heavy metal detecting device of the present invention has the advantages of simplicity and rapidity.

Abstract: A method of evaporation control of a sample which is stored in a thermally insulated state is configured for preventing evaporation or denaturing of the samples and specimens. The method includes carrying the samples contained in individual containers out from a cold container having a capability of cold storage. An elapsed time that each sample container has been removed from the cold container is measured and is compared with a preset time. If the elapsed time is less than the preset time, the sample container can be returned to the cold container. An alarm is output if the elapsed time exceeds the preset time.

Abstract: A multi-channel device includes up to three channels for optical testing of liquid samples. The liquid sample(s) may include surface water, drinking water, processed water or the like. The multi-channel device may include a turbidity channel and a color channel that measure turbidity and color, respectively, of a liquid sample using spectrographic analysis. The multi-channel device may also include a colorimetric channel that measures the concentration of various analytes in a liquid sample, such as free chlorine, total chlorine, copper and phosphate.

Abstract: Systems for analyte detection are disclosed. The system includes absorption channels positioned along a surface of an object. The absorption channels are configured to trap an analyte. The system further includes a sensor embedded in the object and configured to detect the presence of the analyte. The sensor includes a light source configured to transmit light and a detector configured to detect a change in an intensity of light transmitted by the light source. The sensor further includes a cable configured to connect the light source to the detector, wherein the cable comprises detection regions, and wherein the detection regions include a portion of the cable exposed to the analyte in the absorption channel.

Abstract: A system and method for determining characteristics of a multiphase flow in a well/pipe are disclosed. The disclosed system and method use an optical immersion probe including a flow gap across which two or more types of radiation are transmitted in order to measure absorptions of two or more substances within the multiphase flow. Primarily, broadband ultraviolet (UV) and/or near infrared radiations (NIR) are utilized with the probe to gather absorption data at and/or around at least one of the water peaks and at and/or around one or more oil or oil-condensate peaks. This data may be utilized to calculate the water-cut of the multiphase flow over a wider range of gas volume fractions. Additionally, pressure ports having pressure sensors being located on the optical immersion probe for determining the impact pressures and flow rates of different phases of the multiphase flow may also be used.

Abstract: There are provided an SPR sensor cell and sensor, both having very excellent detection sensitivity. The SPR sensor cell includes: an under-cladding layer; a core layer, at least a part of the core layer being adjacent to the under-cladding layer; and a metal layer covering the core layer. The core layer includes a uniform layer and a gradient layer arranged between the uniform layer and the under-cladding layer; a refractive index NCO of the uniform layer satisfies a relationship of 1.34?NCO<1.44; a refractive index NCL of the under-cladding layer and the refractive index NCO of the uniform layer satisfy a relationship of NCO?NCL?0.020; and a refractive index of the gradient layer gradually increases from an under-cladding layer side to a uniform layer side in a thickness direction of the gradient layer within a range of from more than the NCL to less than the NCO.

Abstract: An apparatus for measuring fluid characteristics includes: a solid transparent body including a plurality of internally reflective surfaces defining a n-sided base having a polygonal shape and having at least three sides, each reflective surface forming a side of the polygonal shape, the plurality of surfaces configured to direct the electromagnetic radiation beam along a path within the solid transparent body from an entry area to an exit area on the solid transparent body; an electromagnetic radiation source coupled to the entry area on the solid transparent body; and a detector coupled to the exit area on the solid transparent body and configured to receive at least a fraction of the reflected electromagnetic radiation beam, the detector configured to generate a signal based on the received electromagnetic radiation beam and transmit the signal to a processor for at least one of analysis of material characteristics and data storage.

Abstract: A portable analytical device including at least one optical unit and optionally an adapting device are provided. The optical unit includes a light beam receiving area, a sample holder, a light beam exiting area, and a lens component. The adapting device holds the optical unit and an external hand-held computing device (EHCD), such that the optical unit is coupled to the EHCD.

Abstract: Disclosed is a double-sided grating waveguide biosensor. The double-sided grating waveguide biosensor is used to sense the properties of a sample solution. The double-sided grating waveguide biosensor comprises a sequential stack of a plastic grating having a grating part, a waveguide layer having a double-sided grating structure, and a channel chip. Furthermore, the sample solution is guided into the channel chip; the light beam is coupled into the waveguide layer via the double-sided grating structure, propagates in the waveguide layer, and penetrates outward. The double-sided waveguide biosensor detects the properties of the sample solution via a variation of a light beam intensity of the outgoing light beam.

Abstract: Substrates and methods for in vitro determination of sunscreen protection factors (SPF) are disclosed.

Abstract: A system and method for mounting a section onto a substrate, the system comprising: a fluid channel including: a fluid channel inlet that receives the section, processed from a bulk embedded sample by a sample sectioning module positioned proximal the fluid channel inlet, a section-mounting region downstream of the fluid channel inlet, and a fluid channel outlet downstream of the section-mounting region; a reservoir in fluid communication with the fluid channel outlet; and a manifold, fluidly coupled to the reservoir, that delivers fluid from the reservoir to the fluid channel inlet, thereby transmitting fluid flow that drives delivery of the section from the fluid channel inlet toward the section-mounting region.

Abstract: An absorption cell for microfluidic chemical analysis made from tinted or colored polymers, for example polymethylmethacrylate (PMMA), in which microfluidic channels are cut. Light is coupled into the absorption cell via two windows (typically 200 um thick) that are retained at either end of the channel. Absorption is measured using a light source, such as a light emitting diode (LED) and a photodiode butted against the windows. Spurious scattered and/or reflected light is absorbed by the colored polymer over the length of the measurement cell, while very little light loss occurs at the coupling windows.

Abstract: Optical computing devices are disclosed. One optical computing device includes an electromagnetic radiation source that emits electromagnetic radiation into an optical train to optically interact with a sample and at least one integrated computational element, the sample being configured to generate optically interacted radiation. A sampling window is arranged adjacent the sample and configured to allow transmission of the electromagnetic radiation therethrough and has one or more surfaces that generate one or more stray signals. A first focal lens is arranged to receive the optically interacted radiation and the one or more stray signals and generate a primary focal point from the optically interacted radiation. A structural element defines a spatial aperture aligned with the primary focal point such that the optically interacted radiation is able to pass therethrough while transmission of the one or more stray signals is substantially blocked by the structural element.

Abstract: A liquid sample analyzer includes a flow cell, a light source, and a lamp temperature management system. The flow cell is configured to receive a flow of a liquid sample from a liquid sample source. The light source includes a lamp configured to emit light to illuminate the flow of the liquid sample in the flow cell. The lamp temperature management system includes: an air flow generator operable to generate a turbulent air flow to cool the lamp; a thermally conductive primary housing encapsulating the lamp such that a primary air gap is provided between the primary housing and the lamp; and a thermally conductive secondary housing surrounding the primary housing and configured to deflect the turbulent air flow away from the primary housing.

Abstract: An optical sensor may include a sensor head that has an optical window for directing light into a flow of fluid and/or receiving optical energy from the fluid. The optical sensor may also include a flow chamber that includes a housing defining a cavity into which the sensor head can be inserted. In some examples, the flow chamber includes an inlet port defining a flow nozzle that is configured to direct fluid entering the flow chamber against the optical window of the sensor head. In operation, the force of the incoming fluid impacting the optical window may prevent fouling materials from accumulating on the optical window.

Abstract: An apparatus for taking an accurate photometric measurement of a liquid by way of forming a specimen volume of a controlled optical path length for use with photometric measurement equipment is disclosed herein. In some embodiments, the apparatus comprises a transparent body configured for displacing a volume of a fluid and at least one support element wherein the support element is configured to maintain the transparent body at a location such that specimen fluid may enter a void volume to form a specimen volume of a controlled optical path length. In some embodiments, the apparatus comprises a plurality of transparent bodies interconnected by a web such that the transparent bodies are maintained at a spacing arrangement which allows for them to be inserted into the wells of a microplate in order to create a plurality of specimen volumes of a controlled optical path length.

Abstract: An optical system for acquiring fast spectra from spatially channel arrays includes a light source for producing a light beam that passes through the microfluidic chip or the channel to be monitored, one or more lenses or optical fibers for capturing the light from the light source after interaction with the particles or chemicals in the microfluidic channels, and one or more detectors. The detectors, which may include light amplifying elements, detect each light signal and transducer the light signal into an electronic signal. The electronic signals, each representing the intensity of an optical signal, pass from each detector to an electronic data acquisition system for analysis. The light amplifying element or elements may comprise an array of phototubes, a multianode phototube, or a multichannel plate based image intensifier coupled to an array of photodiode detectors.