Abstract: The present invention relates to a method of identifying types of body fluids in a sample. This method involves providing a sample potentially containing one or more types of body fluids. The sample is subjected to Raman spectroscopy to produce a Raman spectroscopic signature for the sample. The Raman spectroscopy signature is identified to ascertain the types of body fluids in the sample. A method of establishing a reference Raman spectroscopic signature for specific types of body fluids is also disclosed as is a library of such reference signatures is also disclosed.

Abstract: A method for controlling color in printing technology machines, includes measuring color measured values without/with a UV filter and converting them with a computer to color measured values measured with/without a UV filter. The color measured values measured without/with a UV filter are recorded by a color measurement instrument on a substrate. The spectral remission values of the substrate measured with and without a UV filter are supplied to the computer and the computer converts color measured values measured without/with a UV filter to color measured values measured with/without a UV filter taking into account these supplied spectral remission values of the substrate, and uses them to control the color in the printing technology machine. A printing technology machine having a computer for carrying out the method, is also provided.

Abstract: The appearance of a color print viewed under UV illumination is predicted using a target comprising color patches each printed using a known coverage of printer colorant(s). In one case, the target is illuminated using a UV light source and an electronic image of the target is captured using a digital camera or the like. In another case, a spectrophotometer is used both with and without a UV cutoff filter to measure the target. The captured image data or the spectrophotometric measurements are used to derive a UV printer characterization model that relates any arbitrary combination of printer colorants to a predicted UV color appearance value. Metameric colorant mixture pairs for visible light and UV light viewing can be determined using the UV model together with a conventional visible light printer characterization model. A visual matching task is used to determine a correction factor for the UV printer characterization model.

Abstract: An optical sensor, sensing system and method of sensing employ a half-core hollow optical waveguide adjacent to a surface of an optical waveguide layer of a substrate. The half-core hollow optical waveguide and the adjacent optical waveguide layer cooperatively provide both an optical path that confines and guides an optical signal and an internal hollow channel. The optical path and channel extend longitudinally along a hollow core of the half-core hollow optical waveguide. The system further includes an optical source at an input of the optical path and an optical detector at an output of the optical path. A spectroscopic interaction between an analyte material that is introduced into the channel and an optical signal propagating along the optical path determines a characteristic of the analyte material.

Abstract: Apparatus for searching for and detecting defects on parts that are substantially inaccessible, being located behind a wall, the apparatus comprising a first endoscope for illumination in visible light and for observation, the first endoscope and pipes for feeding and spraying penetration test substances being housed together in a rod which can be passed through an orifice in the wall in order to examine a part, the apparatus further comprising a second endoscope independent of the first endoscope and the rod for illuminating in ultraviolet light and for observing the portion of the part that has been treated by the penetration test substances.

Abstract: To provide a device for pasting a film exhibiting dichroism and a film exhibiting birefringence at an arbitrary angle with high precision. The device for pasting a film exhibiting dichroism and a film exhibiting birefringence at an arbitrary angle comprises a detector for detecting the angle of an axis where absorption is maximum or minimum in the plane of a film exhibiting dichroism, and a detector for detecting the slow axis in the plane of a film exhibiting birefringence. An angle between the film exhibiting dichroism and the film exhibiting birefringence is controlled using the detector for a film exhibiting dichroism and the detector for a film exhibiting birefringence.

Abstract: The same analytic data is combined in response to different relative phases. The resulting combinations are detected. The combination associated with the maximum magnitude is then selected for further processing. As a result, the complex data is processed across a variety of possible temporal discontinuities using candidate or possible phase shifts. The phase shift with the least cancellation and the associated combination is selected to minimize motion artifact cancellation.

Abstract: Apparatus for searching for and detecting defects on parts that are substantially inaccessible, being located behind a wall, the apparatus comprising a first endoscope for illumination in visible light and for observation, the first endoscope and pipes for feeding and spraying penetration test substances being housed together in a rod which can be passed through an orifice in the wall in order to examine a part, the apparatus further comprising a second endoscope independent of the first endoscope and the rod for illuminating in ultraviolet light and for observing the portion of the part that has been treated by the penetration test substances.

Abstract: A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.

Abstract: A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.

Abstract: A method and device for fluorimetric determination of a biological, chemical or physical parameter of a sample utilize at least two different luminescent materials, the first of which is sensitive to the parameter, at least with respect to luminescence intensity, and the second of which is insensitive to the parameter, at least with respect to luminescence intensity and decay time. The luminescent materials have different decay times. The time- or phase behaviour of the resulting luminescence response is used to form a reference value for determination of a parameter.

Abstract: Methods for detection and analysis of allosteric receptor/ligand binding by changes in surface refractive index are provided. When analyzed by surface plasmon resonance, binding of such allosteric binding agents to their ligands may result in a negative deviation in the optical response (i.e., a decrease in resonance angle) or in an increase in the optical response (i.e., an increase in resonance angle) depending on the binding properties of the selected allosteric receptor. Other methods for analysis of surface refractive index are also useful in the invention. The methods of the invention are particularly useful for small ligands which would not be expected to produce detectable changes in refractive index because they do not add significant mass upon binding.

Abstract: Disclosed is a method for obtaining feedback to drive a servo system for aligning and maintaining alignment in optical systems that bring light to an in vivo skin sample, for adjusting the focus of the optical system, and for adjusting the net depth of focus of the optical system within the in vivo system under characterization. The invention additionally provides a method for obtaining feedback to drive a servo system for aligning and maintaining alignment in optical systems that collect light from an in vivo skin sample, and for adjusting the focus of the optical system. These methods comprise adjusting the angle of incidence of electromagnetic radiation and/or providing a shielding lens to block scattered incident light, or otherwise limiting the field of view of the Raman scattered radiation collection system to exclude optical surfaces of the excitation delivery portion of the optical system. Also provided is a method for identifying spectroscopic depth markers in tissues.

Abstract: The technical field of the invention is that of searching for or analyzing materials, in particular liquids, by optical means. The method of optically measuring the transparency of a liquid uses a turbidity analyzer comprising at least one emitter of light passing through an optical interface piece providing an interface with the liquid illuminated in this way, and at least one measurement cell receiving a fraction of said light via a second optical interface piece, said fraction having traveled a given distance through said liquid. According to the method of the invention: ultrasound waves are generated in the vicinity of the emitting and receiving optical/liquid interfaces of said optical pieces in contact with said liquid; gaseous microcavities are thus created in the liquid and said interface surfaces are cleaned when said microcavities implode; and the emission of said ultrasound waves is stopped and the light received by the cell is measured.