Telescope Or Microscope Patents (Class 378/43)
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Patent number: 8076654Abstract: The present invention provides a surface inspection method and apparatus for inspecting a surface of a sample, in which a resistive film is coated on the surface, and a beam is irradiated to the surface having the resistive film coated thereon, to thereby conduct inspection of the surface of the sample. In the surface inspection method of the present invention, a resistive film having an arbitrarily determined thickness t1 is first coated on a surface of a sample. Thereafter, a part of the resistive film having the arbitrarily determined thickness t1 is dissolved in a solvent, to thereby reduce the thickness of the resistive film to a desired level. This enables precise control of a value of resistance of the resistive film and suppresses distortion of an image to be detected.Type: GrantFiled: May 19, 2008Date of Patent: December 13, 2011Assignee: Ebara CorporationInventors: Masahiro Hatakeyama, Kenji Watanabe, Takeshi Murakami, Tohru Satake, Nobuharu Noji
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Publication number: 20110266440Abstract: A method of investigating a sample using Scanning Electron Microscopy (SEM), comprising the following steps: Irradiating a surface (S) of the sample using a probing electron beam in a plurality (N) of measurement sessions, each measurement session having an associated beam parameter (P) value that is chosen from a range of such values and that differs between measurement sessions; Detecting stimulated radiation emitted by the sample during each measurement session, associating a measurand (M) therewith and noting the value of this measurand for each measurement session, thus allowing compilation of a data set (D) of data pairs (Pi, Mi), where 1?i?N, wherein: A statistical Blind Source Separation (BSS) technique is employed to automatically process the data set (D) and spatially resolve it into a result set (R) of imaging pairs (Qk, Lk), in which an imaging quantity (Q) having value Qk is associated with a discrete depth level Lk referenced to the surface S.Type: ApplicationFiled: April 29, 2011Publication date: November 3, 2011Applicant: FEI CompanyInventors: Faysal Boughorbel, Cornelis Sander Kooijman, Berend Helmerus Lich, Eric Gerardus Theodoor Bosch
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Patent number: 7970197Abstract: A block of tissue is imaged and used as a reference. Later slides formed from that tissue receive numbers, and are also imaged. The imaged slides are compared to the reference image to determine identification errors.Type: GrantFiled: October 30, 2007Date of Patent: June 28, 2011Assignee: Clarient, Inc.Inventor: Jose de la Torre-Bueno
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Patent number: 7928379Abstract: The invention concerns a phase plate for electron optical imaging, wherein the zero beam (4) is phase-shifted in order to obtain an image with optimum contrast through interference with the diffracted electron beams (5, 5?). The shading of diffracted electron beams (5, 5?) is kept to a minimum and shading that cannot be reconstructed from the obtained image data is prevented. This is achieved in that the electrode (1?) is designed as a shielded conductor (7), which is disposed to extend from a mounting (8) in a substantially radial direction towards the area of the zero beam (4), wherein the shielded conductor (7) has an end (9) in front of the area of the zero beam (4) such that a field (6) is formed between the conductor (7) and the shielding (10) surrounding it, which overlaps this area. The invention also concerns an imaging method for complete reconstruction of the image and an electron microscope (12) which is provided with the phase plate (1).Type: GrantFiled: October 26, 2007Date of Patent: April 19, 2011Assignee: CEOS Corrected Electron Optical Systems GmbHInventor: Joachim Zach
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Patent number: 7885448Abstract: A microscope array with staggered rows of magnifying imaging systems is used to scan a biological tissue sample in a single linear pass to produce an image and corresponding optical-density data. A conventional computerized algorithm is used to identify, isolate and produce segmented images of nuclei contained in the image. The OD values corresponding to nuclear chromatin are used to identify numerical patterns known to have statistical significance in relation to the health condition of the biological tissue. These patterns are analyzed to detect pre-neoplastic changes in histologically normal-appearing tissue that suggest a risk for the development of a pre-malignant and a potentially malignant lesion. This information is then converted to a visually perceptible form incorporated into the image of the tissue sample and is displayed for qualitative analysis by a pathologist.Type: GrantFiled: February 27, 2007Date of Patent: February 8, 2011Assignee: DMetrix, Inc.Inventor: Peter H. Bartels
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Patent number: 7822174Abstract: An x-ray microscope stage enables alignment of a sample about a rotation axis to enable three dimensional tomographic imaging of the sample using an x-ray microscope. A heat exchanger assembly provides cooled gas to a sample during x-ray microscopic imaging.Type: GrantFiled: April 20, 2006Date of Patent: October 26, 2010Assignee: The Regents of the University of CaliforniaInventors: Mark Le Gros, Carolyn A. Larabell
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Patent number: 7796725Abstract: An x-ray imaging system uses a synchrotron radiation beam to acquire x-ray images and at least one integrated x-ray source. The system has an imaging system including sample stage controlled by linear translation stages, objective x-ray lens, and x-ray sensitive detector system, placed on a fixed optical table and a mechanical translation stage system to switch x-ray sources when synchrotron radiation beam is not available.Type: GrantFiled: March 11, 2009Date of Patent: September 14, 2010Assignee: Xradia, Inc.Inventors: Ziyu Wu, Wenbing Yun, Peiping Zhu, Yuxin Wang, Qingxi Yuan, Andrei Tkachuk, Wanxia Huang, Michael Feser
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Patent number: 7792246Abstract: A method and apparatus for providing image data which can be used to construct a high resolution image of a region of a target object is disclosed. An embodiment of the method includes the acts of providing incident radiation from a radiation source at a target object, via at least one detector, detecting the intensity of radiation scattered by the target object and providing the image data responsive to the detected intensity without high resolution positioning of the incident radiation or a post target object aperture relative to the target object.Type: GrantFiled: April 15, 2005Date of Patent: September 7, 2010Assignee: Phase Focus LtdInventors: John Marius Rodenburg, Helen Mary Louise Faulkner
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Patent number: 7787588Abstract: The principle of reciprocity states that full-field and scanning microscopes can produce equivalent images by interchanging the roles of condenser and detector. Thus, the contrast transfer function inversion previously used for images from scanning systems can be applied to Zernike phase contrast images. In more detail, a full-field x-ray imaging system for quantitatively reconstructing the phase shift through a specimen comprises a source that generates x-ray radiation, a condenser x-ray lens for projecting the x-ray radiation onto the specimen, an objective x-ray lens for imaging the x-ray radiation transmitted through the specimen, a phase-shifting device to shift the phase of portions of x-ray radiation by a determined amount, and an x-ray detector that detects the x-ray radiation transmitted through the specimen to generate a detected image.Type: GrantFiled: July 21, 2009Date of Patent: August 31, 2010Assignee: Xradia, Inc.Inventors: Wenbing Yun, Michael Feser, Benjamin Hornberger
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Patent number: 7676258Abstract: A system and method for enhancing images of ex-vivo or in-vivo tissue produced by confocal microscopy, optical coherence tomography, two-photon microscopy, or ultrasound, is provided by applying to the tissue a solution or gel having an effective concentration of citric or other alpha-hydroxy acid which enhances tissue structures, such as cellular nuclei, in such images. Such concentration may be 3-20% acid, and preferably 5% acid.Type: GrantFiled: December 8, 2005Date of Patent: March 9, 2010Assignee: Lucid, Inc.Inventor: Jay M. Eastman
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Patent number: 7655923Abstract: A mesh (M) having an ellipsoid shape or a shape close to the ellipsoid shape is attached to an electrode (EL1) among electrodes (EL1 to ELn). Voltages of the later-stage electrodes (EL2 to ELn) are appropriately set. With this arrangement, a local negative spherical aberration generated by the mesh (M) is cancelled out with a positive spherical aberration. This optimizes an electric field distribution. As a result, this realizes an electrostatic lens whose acceptance angle is extended to about ±60°.Type: GrantFiled: November 9, 2004Date of Patent: February 2, 2010Assignees: National University Corporation Nara Institute of Science and Technology, Jeol, Ltd.Inventors: Hiroshi Daimon, Hiroyuki Matsuda, Makoto Kato, Masato Kudo
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Patent number: 7623620Abstract: There is provided a reflective X-ray microscope for examining an object in an object plane. The reflective X-ray microscope includes (a) a first subsystem, having a first mirror and a second mirror, disposed in a beam path from the object plane to the image plane, and (b) a second subsystem, having a third mirror, situated downstream of the first subsystem in the beam path. The object is illuminated with radiation having a wavelength <100 nm, and the reflective X-ray microscope projects the object with magnification into an image plane.Type: GrantFiled: November 8, 2004Date of Patent: November 24, 2009Assignee: Carl Zeiss SMT AGInventors: Hans-Jürgen Mann, Udo Dinger, Wilhelm Ulrich, Wolfgang Reinecke, Thomas Engel, Axel Zibold, Wolfgang Harnisch, Marco Wedowski, Dieter Pauschinger
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Patent number: 7583787Abstract: A device for improving resolution capability of an x-ray optical apparatus for an x-ray incident from a direction of incidence includes a mirror element including a mirror edge formed as a cylindrical shell section around an edge axis. The mirror element is spaced apart, in a radial direction, from a focal axis that is parallel to the direction of incidence. The edge axis is oriented at a first non-zero angle relative to the focal axis when viewed along a radial axis. The edge axis is oriented at a second non-zero angle relative to the focal axis.Type: GrantFiled: October 30, 2007Date of Patent: September 1, 2009Assignee: Astrium GmbHInventors: Albrecht Frey, Norbert Pailer, Jess Koehler
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Publication number: 20090184252Abstract: Provided is an X-ray analyzer capable of significantly suppressing an influence of an external magnetic field on a transition edge sensor (TES). The X-ray analyzer includes: a TES (7) for detecting energy of a received X-ray as a temperature change and outputting the temperature change as a current signal; a superconducting magnetic shield (8) which contains the TES (7) and enters a superconducting state; and a room temperature magnetic shield (9) which covers the superconducting magnetic shield (8) and performs external magnetic field shielding until the superconducting magnetic shield (8) enters the superconducting state, in which the superconducting magnetic shield (8) and the room temperature magnetic shield (9) are concentrically arranged to have a cylindrical shape.Type: ApplicationFiled: December 23, 2008Publication date: July 23, 2009Inventors: Keiichi Tanaka, Akikazu Odawara, Satoshi Nakayama, Sumio Iijima, Shunji Bandow
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Patent number: 7551722Abstract: Disclosed are an X-ray target having a micro focus size and capable of producing X-rays of high intensity, and apparatuses using such an X-ray target. The X-ray target (1) has a structure in which a first cap layer (21), a target layer (22), and a second cap layer (23) are successively laminated, wherein the first and second cap layers (21 and 23) are each composed of a material which is lower in electron beam absorptivity than that of which the target layer (22) is composed. An X-ray generator using the X-ray target (1) can generate highly intense and nanofocus (several nm) X-rays (17). Using the X-ray generator, an X-ray microscope allows obtaining a high resolution transmission image, an X-ray diffraction apparatus allows obtaining an X-ray diffraction image of a very small area, and a fluorescent X-ray analysis apparatus allows making the fluorescent X-ray analysis of a minute area.Type: GrantFiled: April 8, 2005Date of Patent: June 23, 2009Assignee: Japan Science and Technology AgencyInventors: Ken-ichi Ohshima, Jinpei Harada
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Publication number: 20090135486Abstract: A method and objective apparatus are provided for implementing an enhanced phase contrast microscope. A focusing vortex lens, defined by a diffractive spiral zone plate (SZP) lens, is used for the objective for the phase contrast microscope. The SZP lens focuses and imparts a helical phase to incident illumination to image the specimen with spiral phase contrast. The spiral phase contrast microscope is sensitive to phase gradients in all sample axes. Replacing the objective of a microscope with the diffractive SZP lens of the invention immediately provides existing instruments with spiral phase contrast capability.Type: ApplicationFiled: September 17, 2007Publication date: May 28, 2009Inventor: Ian McNulty
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Patent number: 7499521Abstract: An imaging technology for fuel cells is based on x-ray microscopy. A metrology system images the electro-chemical interaction areas of solid-oxide fuel cells (SOFC) in-situ. This system takes advantage of both the penetrating power and elemental absorption contrast of hard x-ray radiation to image the internal interaction areas in a SOFC. The technology can further take advantage of the strong dependence of the x-ray absorption on material type and energy to distinguish the four major material types: cathode, electrolyte, air, and low-Z contaminants such as sulfur.Type: GrantFiled: January 4, 2007Date of Patent: March 3, 2009Assignee: Xradia, Inc.Inventors: Yuxin Wang, Wenbing Yun
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Publication number: 20090052619Abstract: [Object] To provide a Fresnel zone plate having a complex irradiation function capable of improving resolution even when the outermost opaque band width cannot be reduced and an X-ray microscope using the Fresnel zone plate. [Solution] A Fresnel zone plate 1 having a complex irradiation function according to the present invention has opaque bands 3 and transparent bands 4 arranged alternately in the radial direction from the center on a flat transparent substrate 2, and a transmission window 7 formed such that a portion of a plane wave vertically applied onto the upper surface vertically enters directly a sample 6 disposed below the Fresnel zone plate 1.Type: ApplicationFiled: April 18, 2006Publication date: February 26, 2009Inventor: Hisamitsu Endoh
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Patent number: 7486766Abstract: The present invention provides internal gain charge coupled devices (CCD) and CT scanners that incorporate an internal gain CCD. A combined positron emission tomography and CT scanner is also provided.Type: GrantFiled: February 25, 2008Date of Patent: February 3, 2009Assignee: Radiation Monitoring Devices, Inc.Inventors: Vivek V Nagarkar, Sameer V Tipnis
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Patent number: 7474729Abstract: A soft X-ray microscope includes a table (10); a housing (20) installed to the upper side of the table (10) and having a partition (22); a light source chamber (30) installed lower than the partition (22) of the housing (20) to project a light to liquid jetted under a high pressure to generate plasma; a mirror chamber (40), installed above the partition (22) of the housing (20), in which first and second mirror (410 and 430) are respectively installed to upper and lower sides of a holder (420) for storing a living sample, the soft X-ray generated by the plasma generated in the light source chamber (30) illuminates the living sample, and the soft X-ray penetrated the living sample is amplified to obtain an image in an image capturing chamber; and an image capturing chamber (50) installed to the upper side of the housing (20) to amplify a light image signal amplified through the mirror chamber (40) and to capture the light image on an external screen to allow distinguishing the light image from exterior.Type: GrantFiled: August 28, 2006Date of Patent: January 6, 2009Assignee: Wonkwang University Center for Industry-Academy CooperationInventors: Kwon-ha Yoon, Kyong-woo Kim
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Patent number: 7469039Abstract: A device for generating an x-ray point source includes a target, and an electron source for producing electrons which intersect with the target to generate an x-ray point source having a size which is confined by a dimension of the target.Type: GrantFiled: August 2, 2006Date of Patent: December 23, 2008Assignee: International Business Machines CorporationInventors: Hendrik F. Hamann, Yves Martin, Theodore G. van Kessel, Hemantha K. Wickramasinghe
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Patent number: 7466796Abstract: An improved short-wavelength microscope is described in which a specimen sample is placed between a condenser zone plate lens and an objective zone plate lens so that the specimen is aligned with a diffraction order of the condenser zone plate lens that is greater than one and proximal to the condenser zone plate.Type: GrantFiled: August 5, 2005Date of Patent: December 16, 2008Assignee: Gatan, Inc.Inventor: Scott H. Bloom
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Publication number: 20080240347Abstract: A lens assembly for enhancing the depth of field of a short-wavelength microscopic system is disclosed. The lens assembly includes an objective zone plate lens, an encoding lens, an imaging detector and a decoding component connected to the imaging detector. The objective zone plate lens is oriented to receive short-wavelength radiation that has passed through a sample in a microscopic system. The encoding lens is oriented to receive the short-wavelength radiation that has passed through the objective zone plate lens and encode the radiation to output an encoded short-wavelength radiation. The imaging detector is oriented to receive the encoded short-wavelength radiation and convert it to a digital signal which is subsequently decoded by the decoding component to decode the encoding applied to the short-wavelength radiation.Type: ApplicationFiled: July 24, 2006Publication date: October 2, 2008Applicant: JMAR RESEARCH, INC.Inventor: Scott H. Bloom
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Patent number: 7427757Abstract: X-ray monochromators and electron probe micro-analysis (EPMA) systems using such monochromators are disclosed. A turretless x-ray monochromator may have a cassette of reflectors instead of a turret. The cassette stores a plurality of reflectors that can be inserted into a conventional Rowland circle monochromator geometry. A transfer mechanism selectively moves reflectors from the cassette to a reflector positioner. The use of the cassette allows each reflector to be placed closer to a source of x-rays, thereby allowing a larger solid angle for x-ray collection. An alternative x-ray monochromator uses a non-focusing reflector that can be fixed, scanned axially or scanned radially to provide large solid angle detection of x-rays at various energies with a single reflector.Type: GrantFiled: December 5, 2005Date of Patent: September 23, 2008Assignee: KLA-Tencor Technologies CorporationInventors: Gary R. Janik, Jeffrey A. Moore
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Patent number: 7414245Abstract: A scintillation based imaging system. The device utilizes a single-crystal inorganic scintillator to convert ionizing radiation to light in a spectral range or ranges within the visible or ultraviolet spectral ranges. The conversion takes place inside the single crystal material, preserving special resolution. The single crystal scintillator is sandwiched between a first plate that is substantially transparent to the ionization radiation and a second plate that is transparent to the visible or ultraviolet light. The ionization radiation is directed from the submicron source through a target to create a shadow image of the target inside the scintillator crystal. Several submicron sources of radiation are described. These include submicron x-ray and high-energy ultraviolet sources, submicron electron beam sources, submicron alpha particle sources, submicron proton sources, submicron positron sources and sub-micron neutron sources.Type: GrantFiled: April 20, 2006Date of Patent: August 19, 2008Inventor: Richard G. Trissel
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Patent number: 7412131Abstract: An optic device, system and method for making are described. The optic device includes a first solid phase layer having a first index of refraction with a first photon transmission property and a second solid phase layer having a second index of refraction with a second photon transmission property. The first and second layers are conformal to each other. The optic device may be fabricated by vapor depositing a first layer and then vapor depositing a second layer thereupon. The first layer may be deposited onto a blank or substrate. The blank or substrate may be rotated during deposition. Further, a computer-controlled shutter may be used to alter the deposition rate of material along an axis of the optic device. Alternatively, the optic device may be moved at varying speeds through a vapor stream to alter the deposition rate of material.Type: GrantFiled: January 2, 2007Date of Patent: August 12, 2008Assignee: General Electric CompanyInventors: Susanne Madeline Lee, Forrest Frank Hopkins
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Patent number: 7406151Abstract: An x-ray microscope uses a microfocus x-ray source with a focus spot of less than 10 micrometers and a Wolter condenser having a magnification of about four or more for concentrating x-rays from the source onto a sample. A detector is provided for detecting the x-rays after interaction with the sample, and an x-ray objective is used to form an image of the sample on the detector. The use of the Wolter optic addresses a problem with microfocus sources that arise when the size of the focal spot that must then be imaged onto the sample with the condenser is smaller than the field of view.Type: GrantFiled: September 21, 2006Date of Patent: July 29, 2008Assignee: Xradia, Inc.Inventors: Wenbing Yun, Yuxin Wang, Michael Feser, Frederick W. Duewer
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Publication number: 20080159472Abstract: The present invention describes a device for improving the resolution capability of an x-ray optical apparatus for an x-ray (24) incident from a direction of incidence, which device comprises a mirror element (52, 54) with a mirror edge (52), the mirror edge (52) being formed around an edge axis (58) by a cylindrical shell section, the mirror element (52, 54) being arranged spaced apart in a radial direction (42) with respect to a focal axis (25) parallel to the direction of incidence by a focal point of the x-ray optical apparatus, and the mirror element (52, 54) being furthermore arranged rotated about an axis extending in the radial direction (42) with respect to the direction of incidence such that the edge axis (58) is tilted with respect to the direction of incidence.Type: ApplicationFiled: October 30, 2007Publication date: July 3, 2008Applicant: ASTRIUM GmbHInventors: Albrecht Frey, Norbert Pailer, Jess Koehler
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Patent number: 7394890Abstract: An x-ray imaging system uses particular emission lines that are optimized for imaging specific metallic structures in a semiconductor integrated circuit structures and optimized for the use with specific optical elements and scintillator materials. Such a system is distinguished from currently-existing x-ray imaging systems that primarily use the integral of all emission lines and the broad Bremstralung radiation. The disclosed system provides favorable imaging characteristics such as ability to enhance the contrast of certain materials in a sample, to use different contrast mechanisms in a single imaging system, and to increase the throughput of the system.Type: GrantFiled: November 8, 2004Date of Patent: July 1, 2008Assignee: Xradia, Inc.Inventors: Yuxin Wang, Wenbing Yun, Frederick William Duewer
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Publication number: 20080119060Abstract: Inspection systems and methods are disclosed. A preferred embodiment comprises an inspection system including a support for a reticle and a microscope including a lens system. The lens system includes at least one lens comprising at least one Fresnel element, wherein the at least one Fresnel element is non-circular.Type: ApplicationFiled: November 17, 2006Publication date: May 22, 2008Inventor: Francis Goodwin
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Patent number: 7342995Abstract: A specific macromolecule crystal evaluating device according to the present invention is equipped with a sample detecting stage for detecting a protein crystal in a sample container, an X-ray measuring stage that is spaced from the sample detecting stage and carries out X-ray diffraction measurement of the protein crystal, a feeding unit for feeding the sample container from the sample detecting stage to the X-ray measuring stage, and a central processing unit for recognizing the position of the protein crystal on the basis of the information achieved in the sample detecting stage and controlling the feeding unit on the basis of the position information to position the protein crystal to a sample disposing portion of the X-ray measuring stage.Type: GrantFiled: August 18, 2004Date of Patent: March 11, 2008Assignees: Rigaku Corporation, RIKENInventors: Takahisa Sato, Akihito Yamano, Shoichi Yasukawa, Hiroki Yoshida, Kensaku Hamada
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Patent number: 7289597Abstract: An optical axis adjusting mechanism for an X-ray lens, an X-ray analytical instrument and a method of adjusting an optical axis of an X-ray lens, capable of enhancing detection efficiency of an X-ray while preventing degradation of the device performance are provided. An optical axis adjusting mechanism for an X-ray lens to be implemented in an X-ray analytical instrument, includes an exit side adjusting mechanism for adjusting an exit side focal point of the X-ray lens to focus on an X-ray detector, and an entrance side adjusting mechanism for adjusting an entrance side focal point of the X-ray lens to focus on an analytical point of a sample, and the entrance side adjusting mechanism is disposed with a greater distance from the X-ray lens than a distance between the exit side adjusting mechanism and the X-ray lens.Type: GrantFiled: March 24, 2006Date of Patent: October 30, 2007Assignee: SII NanoTechnology Inc.Inventors: Norio Sasayama, Akikazu Okawara, Satoshi Nakayama
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Patent number: 7221731Abstract: To provide an X-ray microscopic inspection apparatus capable of performing non-destructive inspection with high resolving power within a very short period, and having advantageous functions such as a high precision electron probe control function, a CT function, an elemental analysis function, and a target switching function. The apparatus includes a magnetic superposition lens having a magnetic field generating portion disposed in the vicinity of an electron generating portion of an electron gun; reflected electron detecting means having a detecting portion disposed above the target for X-ray generation, for detecting a reflected electron from the target; and electron image generating means for performing imaging of a target surface utilizing the signals from the reflected electron detecting means, wherein the apparatus is arranged so that alignment including focus adjustment to the target for X-ray generation and astigmatism correction may be performed based on image information of the electron image.Type: GrantFiled: November 21, 2003Date of Patent: May 22, 2007Assignee: Tohken Co., Ltd.Inventors: Keiji Yada, Hiromi Kai, Yasushi Saito
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Patent number: 7218703Abstract: To provide an X-ray microscopic inspection apparatus capable of performing non-destructive inspection with high resolving power equal to or less than 0.1 ?m in a very short period, and largely contributing to the nano-technology field. In the X-ray microscopic inspection apparatus having X-ray generating means for generating an X-ray by allowing an electron beam from an electron source to impinge on a target for X-ray generation, for inspecting an object to be inspected by utilizing the X-ray, a magnetic field superposition lens having a magnetic field generating portion disposed in the vicinity of an electron generating portion of an electron gun is included as a component element of the X-ray generating means. Further, the apparatus includes a liquid metal electron source using liquid metal or a thermal field emission electron source as the electron source, as a component element of the X-ray generating means.Type: GrantFiled: November 21, 2003Date of Patent: May 15, 2007Assignee: Tohken Co., Ltd.Inventors: Keiji Yada, Hiromi Kai, Yasushi Saito
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Patent number: 7183547Abstract: An element-specific imaging technique utilizes the element-specific fluorescence X-rays that are induced by primary ionizing radiation. The fluorescence X-rays from an element of interest are then preferentially imaged onto a detector using an optical train. The preferential imaging of the optical train is achieved using a chromatic lens in a suitably configured imaging system. A zone plate is an example of such a chromatic lens; its focal length is inversely proportional to the X-ray wavelength. Enhancement of preferential imaging of a given element in the test sample can be obtained if the zone plate lens itself is made of a compound containing substantially the same element. For example, when imaging copper using the Cu La spectral line, a copper zone plate lens is used.Type: GrantFiled: November 23, 2004Date of Patent: February 27, 2007Assignee: Xradia, Inc.Inventors: Wenbing Yun, Kenneth W. Nill
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Patent number: 7177389Abstract: An apparatus for imaging objects with x rays using an x-ray tube, refractive x-ray lens and area detector. Cross sectional images of individual planes within an object are achieved through tomographic and laminographic exposure and image processing. The use of refractive x-ray lenses to achieve high resolution eliminates the need for vanishingly small microspot x-ray sources to achieve high resolution that current x-ray tomographic and laminographic systems suffer.Type: GrantFiled: January 7, 2005Date of Patent: February 13, 2007Assignee: Adelphi TechnologyInventor: Charles K. Gary
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Patent number: 7173999Abstract: Soft X-rays are very suitable for the examination of biological samples by means of an X-ray microscope. The X-rays are generated by focusing an electron beam onto a fluid jet, thus producing a very small electron focus on the jet and hence a very small monochromatic X-ray spot. The electron spot can be obtained by means of a standard electron microscope (a SEM) or by means of a standard electron gun for a cathode ray tube (a CRT gun). The imaging optical elements in the X-ray microscope may be Fresnel zone plates.Type: GrantFiled: December 19, 2000Date of Patent: February 6, 2007Assignee: Koninklijke Philips Electronics N.V.Inventor: Bart Buijsse
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Patent number: 7170969Abstract: A radiation condenser system for an X-ray microscope allows for the efficient collection and relay of radiation from a source to the sample. It generates a converging hollow cone of radiation that can be used in the imaging of a sample or target using a zone plate lens. This system comprises a capillary tube for receiving and focusing radiation onto a sample. A center stop is provided for blocking radiation being transmitted along an axis of the capillary tube.Type: GrantFiled: November 7, 2003Date of Patent: January 30, 2007Assignee: Xradia, Inc.Inventors: Wenbing Yun, Frederick William Duewer, Yuxin Wang
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Patent number: 7155049Abstract: An imaging apparatus is disclosed. The imaging apparatus includes a motorized stage, a camera focussed relative to the stage, and a processor coupled to the camera. The processor contains instructions which, when executed by the processor, cause the processor to capture an image incident on the camera, convert the image into a plurality of pixels having a characteristic such as intensity, establish the characteristic for each pixel; and determine which pixels contain a target image based on the characteristic of the pixels. Another imaging apparatus includes a motorized stage, a camera having a lens directed toward the motorized stage, and a processor coupled to the camera.Type: GrantFiled: July 31, 2001Date of Patent: December 26, 2006Assignee: Trestle Acquisition Corp.Inventors: Arthur W. Wetzel, John R. Gilbertson, II, Jeffrey A. Beckstead, Patricia A. Feineigle, Christopher R. Hauser, Frank A. Palmieri, Jr.
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Patent number: 7136539Abstract: The present invention is a method and apparatus for drug sample identification, including a scale for weighing a drug sample and an imaging module for capturing digital images of the drug sample, from at least two different visual perspectives simultaneously, and an transmitting the collected data and images, via an interface, to a computer for storage and association with an image database.Type: GrantFiled: July 25, 2002Date of Patent: November 14, 2006Inventor: John A. Weyl
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Patent number: 7119953Abstract: A phase contrast x-ray microscope has a phase plate that is placed in proximity of and attached rigidly to the objective to form a composite optic. This enables easier initial and long-term maintenance of alignment of the microscope. In one example, they are fabricated on the same high-transmissive substrate. The use of this composite optic allows for lithographic-based alignment that will not change over the lifetime of the instrument. Also, in one configuration, the phase plate is located between the test object and the objective.Type: GrantFiled: December 27, 2002Date of Patent: October 10, 2006Assignee: Xradia, Inc.Inventors: Wenbing Yun, Yuxin Wang
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Patent number: 7039157Abstract: An X-ray microscope apparatus includes an X-ray generator, a photocathode disposed on a path of X-rays for producing electrons when irradiated with X-rays generated by the X-ray generator, an electron image enlarging device having an acceleration anode for accelerating electrons produced by the photocathode and a magnetic lens for enlarging and focusing an electron beam of electrons emitted by the photocathode, an electron beam detecting device for detecting the electron beam focused thereon by the electron image enlarging device; and an image processing device for processing an electron image formed by the electron beam detecting device. The X-ray microscope apparatus can be formed in compact construction.Type: GrantFiled: July 7, 2003Date of Patent: May 2, 2006Assignee: Kawasaki Jukogyo Kabushiki KaishaInventors: Sadao Fujii, Mikio Muro, Eiji Sato
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Patent number: 7023953Abstract: An optical apparatus and method guide EUV radiation to a predetermined surface. A radiation source supplies EUV radiation having a certain dispersion angle. An illumination optical system having a reflective integrator forms a secondary radiation source having a predetermined shape based on the EUV radiation supplied from the radiation source. A projection optical system is arranged in an optical path between a reflective mask and the predetermined surface and forms an image of the reflective mask onto the predetermined surface based on the EUV radiation from the reflective mask. The secondary radiation source having the predetermined shape has a shape that is a substantially circular shape, an annular shape, or a multipolar shape.Type: GrantFiled: October 20, 2003Date of Patent: April 4, 2006Assignee: Nikon CorporationInventor: Hideki Komatsuda
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Patent number: 7023954Abstract: A method for X-ray analysis of a sample includes aligning an optical radiation source with an X-ray excitation source, so that a spot on the sample that is irradiated by an X-ray beam generated by the X-ray excitation source is illuminated with optical radiation generated by the optical radiation source. Optical radiation that is reflected from the sample is used to generate a first signal, which is indicative of an alignment of the spot on the sample. The X-ray beam is aligned, responsively to the first signal, so that the spot coincides with a target area of the sample. X-ray photons received from the spot on the sample, after aligning the X-ray beam, are used in generating a second signal that is indicative of a characteristic of the target area.Type: GrantFiled: September 29, 2003Date of Patent: April 4, 2006Assignee: Jordan Valley Applied Radiation Ltd.Inventors: Tzachi Rafaeli, Isaac Mazor
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Patent number: 6996207Abstract: X-ray microscope comprise extended X-ray source, as well as means for placement of test object 3 and recording means, and located between them X-ray capillary lens. Channels of the latter are diverging towards recording means. Means for placement of the test object is located between extended X-ray source and lesser end side of the X-ray capillary lens. The device is characterized in that the walls of the channels (14, 16) for radiation transmission have a coating or are made of material absorbing or scattering X-ray radiation, and have lateral surface shape of truncated cone or pyramid, or that of cylinder or prism. With specified choice of the material, phenomenon of total external reflection is excluded, while rectilinearity of longitudinal axes of the channels ensures their functioning as collimators. Therefore, channels capture radiation only from the fragments of the test object 3 situated exactly opposite their entrances.Type: GrantFiled: March 5, 2002Date of Patent: February 7, 2006Inventor: Muradin Abubekirovich Kumakhov
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Patent number: 6907137Abstract: The method for adapting the lateral and temporal resolution of a microscope image allows the detection of temporal changes in the image content, and switches over to another transmission mode on the basis of the result of the determination. The arrangement for adapting the lateral and temporal resolution of a microscope image comprises means for detecting the changes in the image content of a microscopic image. Also provided are electronic means for limiting the image content. Further means make it possible to switch over automatically to a suitable transmission mode. The means for detecting the change is an image data processing means (22) that ascertains salient image points and their positions within a defined image window. In addition, a comparison element (36) is provided and is connected to a switchover means (33).Type: GrantFiled: June 25, 2001Date of Patent: June 14, 2005Assignee: Leica Microsystems Wetzlar GmbHInventor: Helmut Ruehl
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Patent number: 6898270Abstract: An X-ray optical system with an X-ray source (Q) and a first graded multi-layer mirror (A), wherein the extension Qx of the X-ray source (Q) in an x direction perpendicular to the connecting line in the z direction between the X-ray source (Q) and the first graded multi-layer mirror (A) is larger than the region of acceptance (F) of the mirror (A) at a focus (Oa) of the mirror (A) in the x direction, is characterized in that a first collimator (bl) is disposed at a focus of the first graded multi-layer mirror (A) between the X-ray source (Q) and the mirror (A) whose opening in the x direction corresponds to the region of acceptance of the first graded multi-layer mirror (A) and the separation qzA between first collimator (bl) and X-ray source (Q) is: qzA=Qx/tan ?x, wherein ?x is the angle subtended by the first graded multi-layer mirror (A) in the x direction, as viewed from the first collimator (bl).Type: GrantFiled: December 9, 2002Date of Patent: May 24, 2005Assignee: Bruker Axs GmbHInventors: Joachim Lange, Detlef Bahr, Kurt Erlacher
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Patent number: 6894837Abstract: Imaging system for a microscope based on extreme ultraviolet (EUV) radiation. The present invention is directed to a reflective imaging system for an x-ray microscope for examining and object in an object plane, wherein the object is illuminated by rays of a wavelength of less than 100 nm, particularly less than 30 nm, and is imaged in a magnified manner in an image plane. In the imaging system, according to the invention, for a microscope based on extreme ultraviolet (EUV) radiation with wavelengths in the range of less than 100 nm, with a magnification of 0.1× to 1000× and a structural length of less than 5 m, at least one of the imaging optical elements 2 and 3 in the beam path has a diffractive-reflective structure which is arranged on a spherical or plane area and has a non-rotationally symmetric, asymmetric shape. The arrangement according to the invention provides an imaging system which avoids the disadvantages of the prior art and ensures a high imaging quality.Type: GrantFiled: July 24, 2003Date of Patent: May 17, 2005Assignee: Carl Zeiss Microelectric Systems GmbHInventors: Hans-Juergen Dobschal, Thomas Scheruebl, Robert Brunner, Norbert Rosenkranz, Joern Greif-Wuestenbecker
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Patent number: 6859516Abstract: The invention is based on a method for examining structures on a semiconductor substrate. The structures are imaged with X-radiation in an X-ray microscope. The wavelength of the X-radiation is established as a function of the thickness of the semiconductor substrate in such a way that both a suitable transmission of the X-radiation through the semiconductor substrate and a high-contrast image are obtained. As a result, the structures can be observed continuously with short exposure times, high resolution and even while they are in operation.Type: GrantFiled: February 14, 2001Date of Patent: February 22, 2005Assignee: Leica Microsystem Lithography GmbHInventors: Gerd Schneider, Bastian Niemann, Dirk Hambach
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Publication number: 20040264637Abstract: A miniature, ultra-high resolution, and color scanning microscope using microchannel and solid-state technology that does not require focus adjustment. One embodiment includes a source of collimated radiant energy for illuminating a sample, a plurality of narrow angle filters comprising a microchannel structure to permit the passage of only unscattered radiant energy through the microchannels with some portion of the radiant energy entering the microchannels from the sample, a solid-state sensor array attached to the microchannel structure, the microchannels being aligned with an element of the solid-state sensor array, that portion of the radiant energy entering the microchannels parallel to the microchannel walls travels to the sensor element generating an electrical signal from which an image is reconstructed by an external device, and a moving element for movement of the microchannel structure relative to the sample.Type: ApplicationFiled: June 30, 2003Publication date: December 30, 2004Applicant: National Aeronautics and Space AdministrationInventor: Yu Wang