Responsive To Liquid Level Patents (Class 422/106)
  • Patent number: 6426044
    Abstract: Racks having sample containers mounted therein are transported within an analytical system so that a robotic arm can remove the sample containers and deliver them to a desired location within the system. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. Sample tube racks are seated within the in-feed and are transported onto a cross-feed. The cross-feed comprises a movable track having a platform mounted thereto. The cross-feed moves the sample tube racks from a position behind the in-feed to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: July 30, 2002
    Assignee: Bayer Corporation
    Inventors: Beri Cohen, Thomas W. DeYoung, Krunoslav Esteban Draganovic, Paul E. Purpura
  • Patent number: 6413475
    Abstract: An automatic analysis apparatus with a liquid level detection function includes a pipetting device for pipetting a liquid sample from a sample cup to a reaction container by using a pipetting probe that serves as a first capacitor electrode. A sample cup holding means serves as a second capacitor electrode having a ground potential. The conductor material is arranged along a direction in which the pipetting probe moves down for pipetting and is separate from the pipetting device. The conductor material has the same ground potential as that of the sample cup holding means and also serves as a second electrode whereby at any one time either of the sample cup holding means and the conductive material serves as a second capacitor electrode in combination with the first capacitor electrode.
    Type: Grant
    Filed: October 29, 1998
    Date of Patent: July 2, 2002
    Assignee: Hitachi, Ltd.
    Inventors: Masato Ishizawa, Akira Inagaki, Ryuji Tao
  • Publication number: 20020081235
    Abstract: The invention relates to a method and apparatus for controlling the dissociation of water into hydrogen and oxygen, the method including contacting a quantity of aqueous liquid with a quantity of dissociation initiating material in a reaction vessel; monitoring the temperature and/or pressure in the reaction vessel; monitoring the surface area of dissociation initiating material in contact with the aqueous liquid; and controlling the surface area of dissociation initiating material in contact with the aqueous liquid in response to the temperature, pressure, or both, or changes therein, or both, in the reaction vessel.
    Type: Application
    Filed: July 13, 2001
    Publication date: June 27, 2002
    Inventors: Edward W. Baldwin, Russell P. White
  • Patent number: 6391192
    Abstract: An automated apparatus for introducing a mixed liquid base (lime) in a first container or tank (106, 106A) into a biological sludge in a second container (110, 110A and 110B) is described. The second container is used to house the sludge for a short period of time (2 to 12 hours) and then the liquid sludge is sent to a storage tank (112) for a longer period of time (6 months). The system (100) enables flushing of the lime supply conduits (108, 108A and 108B) with water to prevent clogging. The treated sludge is applied to soil as a fertilizer.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: May 21, 2002
    Assignee: HTI, Inc.
    Inventor: Roger Haag
  • Patent number: 6387251
    Abstract: An apparatus for dosing a granulated or powdered additive in the water of a water works includes a dosing assembly (10) with a water collecting tank (9) hydraulically connected to inflows (20, 21) of unmixed water and to an outflow of additive-mixed water (33) to the works. Unmixed water is tapped through a duct (41) from an inflow and fed to a substantially tubular manifold (18), upwardly connected to tank (19). The additive is delivered into manifold (18), in which the additive mixes with water tapped from the inflow through duct (41) and additive-mixed water discharges into collecting tank (19).
    Type: Grant
    Filed: August 28, 2000
    Date of Patent: May 14, 2002
    Assignee: Sintec S.r.l.
    Inventors: Luigi Marsiglietti, Sergio Milli, Giorgio Cesarini
  • Publication number: 20020015676
    Abstract: A process for producing a purified aqueous hydrogen peroxide solution, comprising passing a charged aqueous hydrogen peroxide solution containing impurities through a purifier tower packed with an ion exchange resin, a chelate resin or an adsorption resin to thereby purify the charged aqueous hydrogen peroxide solution, wherein there are provided a feed pump of given output capable of causing the charged aqueous hydrogen peroxide solution to flow to the purifier tower and further a flow sensor capable of sensing a flow rate of charged aqueous hydrogen peroxide solution being fed to the purifier tower and wherein the output of the feed pump is controlled in cooperation with the flow sensor so as to bring the charged aqueous hydrogen peroxide solution into contact with the ion exchange resin, chelate resin or adsorption resin while maintaining the flow of charged aqueous hydrogen peroxide solution at a constant rate.
    Type: Application
    Filed: May 14, 2001
    Publication date: February 7, 2002
    Applicant: SANTOKU CHEMICAL INDUSTRIES CO., LTD
    Inventors: Fujio Tanaka, Takashi Adachi, Toshimi Suzuki, Mutsuro Noguchi, Tomoaki Kobayashi
  • Patent number: 6322752
    Abstract: A method and apparatus for aspirating and dispensing precise volumes of liquid, e.g. whole blood, comprises an aspiration probe or needle having an internal volume precisely equal to a desired volume to be dispensed, and a computer-controlled shear valve for trapping aspirated liquid inside the probe for subsequent dispensing. A liquid sensor positioned downstream of the shear valve cooperates with a liquid level sensor on the probe tip to assure that the probe lumen is filled with the aspirated liquid.
    Type: Grant
    Filed: September 8, 1999
    Date of Patent: November 27, 2001
    Assignee: Coulter International Corp.
    Inventors: Imran T. Siddiqui, Roberto del Valle, Santos Vargas, Pedro P. Cabrera
  • Patent number: 6212949
    Abstract: A fluid level sensor and a washer unit are provided for an automated immonoassay processing system. A washer head (13) is vertically movable by a drive (2) above a reaction tray (8) having fluid (15) in separate cells. The level sensor comprises two electrodes arranged along a fluid path within aspirator tips (6). The electrodes are held at different electrical potentials and are effectively insulated from each other. If fluid is aspirated along the fluid path then the electrodes are bridged. Control means (1) is arranged to detect any change in conductance between the electrodes thereby indicating the presence of fluid (15). The vertical height of the washer head is determined relative to the sample thereby enabling the device to determine the level of the fluid (15).
    Type: Grant
    Filed: September 1, 1998
    Date of Patent: April 10, 2001
    Assignee: Dynex Technologies (Guernsey) Ltd.
    Inventors: David John Inder, Paul Anthony Higgs, Peter John Le Feuvre
  • Patent number: 6149880
    Abstract: A hydrothermal reaction is performed on an aqueous medium without adding an oxidizing agent, and then another hydrothermal reaction is performed in the presence of an oxidizing agent, thereby reducing a chemical oxygen demand of the aqueous medium. An apparatus for performing a hydrothermal reaction has a fluid inlet being capable of introducing an oxidizing agent in a fluid form during a hydrothermal reaction.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: November 21, 2000
    Assignee: Ebara Corporation
    Inventors: Tsutomu Higo, Roberto Masahiro Serikawa, Kazuhiro Kondo
  • Patent number: 6100094
    Abstract: In the present invention, a disposable tip or a tip of a cleaning system is attached to a lower edge section of a nozzle, and the nozzle detects a liquid level by receiving fluctuation of a light close to the disposable tip or to an opening section at a lower end of the tip in the cleaning system, for instance, a light reflected from the liquid surface. In the present invention, not only the liquid level is detected, but also a liquid is filled in the disposable tip or the tip of a cleaning system detachably attached to the nozzle, a light is passed through the liquid in the disposable tip or the tip of a cleaning system, and a change of a light amount of the sucked liquid is detected, so that, for instance, a suction rate of the liquid, transparency thereof, contaminated by bubbles therein, clogging and a state wherein water has been exhausted are determined.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: August 8, 2000
    Assignee: Precision System Science Co., Ltd.
    Inventor: Hideji Tajima
  • Patent number: 6086832
    Abstract: An apparatus for evaluating a solid catalyst which can enlarge a range of an applied fluid used for an evaluation of a performance of the solid catalyst and can accurately evaluate the performance of the solid catalyst on a laboratory scale and a method of evaluating a solid catalyst using the apparatus are provided.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: July 11, 2000
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventor: Nobuyuki Ohta
  • Patent number: 6063634
    Abstract: A fluid assembly and a method are provided. In one embodiment, the fluid assembly is insertable into a container holding a first fluid to be supplied to a diagnostic instrument and comprises a first element, a second element, and a first conduit fluidly connected between the first element and the second element such that the first fluid in the container moves through the first conduit towards the diagnostic instrument. A second conduit containing a second fluid is fluidly connected between the first element and the second element. A pressure transducer is fluidly connected with the second conduit such that the second fluid is bounded within the second conduit by the first fluid and the pressure transducer. The pressure transducer monitors pressure of the second fluid to indicate a volume of the first fluid in the container.
    Type: Grant
    Filed: April 1, 1998
    Date of Patent: May 16, 2000
    Assignee: Abbott Laboratories
    Inventors: Chester Chomka, Ted Hanagan, Stacie Lynn Hoskins, Steven C. Peake, Arthur D. Rokusek, Scott G. Safar, John Willmes
  • Patent number: 6036928
    Abstract: A sterilizing machine facilitates the introduction of a bath liquid into empty crevasses in the article to be sterilized by evacuating a chamber holding the article to be sterilized prior to covering the article with a bath of liquid. The sterilizer equipment also applies a high pressure to the article to enhance killing of organisms contained therein.
    Type: Grant
    Filed: February 10, 1998
    Date of Patent: March 14, 2000
    Inventor: William A Barnstead
  • Patent number: 6027638
    Abstract: An improved automatic filtration and extraction device is disclosed which comprises a base defining at a top end a cavity area which tapers downwardly and inwardly from the top end to define a chamber for a portion and then defines a plurality of effluent outlets at the bottom end each extending from the chamber to an outer surface of the body. Seals are adapted to each of the effluent outlets and are moveable between a first closed position sealing the effluent outlet and a second open position to allow the passage of effluent through the effluent outlet. A filter is detachably and removably adapted over the cavity area. Various solvents are provided to the cavity area through a solvent provider. A circuit with programmable memory accesses and directs a sequence of events after an initial event. A vacuum connected to each of the effluent outlets each induces effluent flow through an effluent outlet while sealing all other outlets.
    Type: Grant
    Filed: May 11, 1998
    Date of Patent: February 22, 2000
    Inventor: Robert S. Johnson
  • Patent number: 6007787
    Abstract: A reaction vessel for processing liquid petroleum or chemical streams wherein the stream flows countercurrent to the flow of a treat gas, such as a hydrogen-containing gas, in at least one interaction zone. The reaction vessel contains vapor, and optionally liquid, passageways to bypass one or more packed beds, preferably catalyst beds. This permits more stable and efficient vessel operation.
    Type: Grant
    Filed: August 23, 1996
    Date of Patent: December 28, 1999
    Assignee: Exxon Research and Engineering Co.
    Inventors: Ramesh Gupta, David C. Dankworth, Dennis D. Fleming, Edward S. Ellis, James J. Schorfheide
  • Patent number: 5965447
    Abstract: A filling process for filling an analytic liquid in a container is optically accurately and automatically carried out using a laser beam. An automatic filling system is capable of automatically and continuously cleaning and drying the container in pretreating processes prior to an analysis.
    Type: Grant
    Filed: August 10, 1998
    Date of Patent: October 12, 1999
    Assignee: Shigetoshi Sekiyama
    Inventors: Shigetoshi Sekiyama, Toshikazu Ogawa, Shigeyuki Koike, Toyoki Sugiyama, Yasunobu Horiguchi
  • Patent number: 5942197
    Abstract: A reactor is provided for reacting a liquid with a treat gas in the presence of a catalyst, the reactor comprising a continuous wall enclosing a first reaction zone, wherein the first reaction zone includes a catalyst for causing a desired reaction between the liquid and the treat gas; a liquid inlet above the first reaction zone for allowing a portion of the liquid to enter the reactor; a gas inlet below the first reaction zone for allowing a portion of the treat gas to enter the reactor; a liquid outlet below the first reaction zone for allowing a reacted portion of the liquid to exit the reactor; a gas outlet above the first reaction zone for allowing a portion of the treat gas to exit the reactor; and a gas bypass device in the first reaction zone for allowing a portion of the treat gas to bypass a portion of the first reaction zone, the gas bypass device including a gas bypass regulating device for regulating the amount of treat gas which bypasses the first reaction zone.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: August 24, 1999
    Assignee: Exxon Research and Engineering Co
    Inventors: Ramesh Gupta, Jeffrey W. Frederick, Edward S. Ellis, David C. Dankworth, Dimitrios M. Tsangaris
  • Patent number: 5939031
    Abstract: A reactor is provided for reacting a liquid with a treat gas in the presence of a catalyst, the reactor comprising a continuous wall enclosing a first reaction zone, wherein the first reaction zone includes a catalyst for causing a desired reaction between the liquid and the treat gas; a liquid inlet above the first reaction zone for allowing an unreacted portion of the liquid to enter the reactor; a gas inlet below the first reaction zone for allowing an unreacted portion of the treat gas to enter the reactor; a liquid outlet below the first reaction zone for allowing a reacted portion of the liquid to exit the reactor; a gas outlet above the first reaction zone for allowing a reacted portion of the treat gas to exit the reactor; and a liquid bypass device in the first reaction zone for allowing a portion of the liquid to bypass a portion of the first reaction zone, the liquid bypass device including a liquid bypass regulating device for regulating the amount of liquid which bypasses the first reaction zone.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: August 17, 1999
    Assignee: Exxon Research and Engineering Co.
    Inventors: Edward S. Ellis, Jeffrey W. Frederick, Ramesh Gupta, David C. Dankworth, Dimitrios M. Tsangaris
  • Patent number: 5919706
    Abstract: In the present invention, a disposable tip or a tip of a cleaning system is attached to a lower edge section of a nozzle, and the nozzle detects a liquid level by receiving fluctuation of a light close to the disposable tip or to an opening section at a lower end of the tip in the cleaning system, for instance, a light reflected from the liquid surface. In the present invention, not only the liquid level is detected, but also a liquid is filled in the disposable tip or the tip of a cleaning system detachably attached to the nozzle, a light is passed through the liquid in the disposable tip or the tip of a cleaning system, and a change of a light amount of the sucked liquid is detected, so that, for instance, a suction rate of the liquid, transparency thereof, contaminated by bubbles therein, clogging and a state wherein water has been exhausted are determined.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: July 6, 1999
    Assignee: Precision System Science Co., Ltd.
    Inventor: Hideji Tajima
  • Patent number: 5914047
    Abstract: A biohazardous liquid medical waste collection and treatment system provides on-site collection and treatment of surgical fluids. The system is mobile, and includes an upper unit and one or more lower units that are detachable from the upper unit. The upper unit includes a liquid disinfectant reservoir, liquid pump valves, and an electronic control unit which controls the operation of the pump valves. A disposable suction canister is mounted to the upper unit and collects liquid medical waste aspirated from a patient. A disposable tube set, including a motionless mixer, is connected to the disposable suction canister and the liquid disinfectant reservoir. Electronically controlled pumps (preferably peristaltic pumps) pump liquid waste from the suction canister along with the metered amount of liquid disinfectant from the liquid disinfectant reservoir through the motionless mixer and into a temporary storage receptacle on the lower unit.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: June 22, 1999
    Assignee: Grifco, LLC
    Inventor: Gerald R. Griffiths
  • Patent number: 5906943
    Abstract: The present invention is directed toward monitoring a thermally driven gas evolving chemical reaction with an acoustic apparatus. Signals from the acoustic apparatus are used to control a heater to prevent a run-away condition. A digestion module in combination with a robotic arm further automate physical handling of sample material reaction vessels. The invention is especially useful for carrying out sample procedures defined in EPA Methods SW-846.
    Type: Grant
    Filed: August 14, 1996
    Date of Patent: May 25, 1999
    Assignee: Battelle Memorial Institute
    Inventors: James R. Skorpik, Michael G. Dodson
  • Patent number: 5902548
    Abstract: An automatic chemistry analyzer is provided having a high throughput and a high reliability. The analyzer uses nephelometric and turbimetric analyzers to analyze a wide variety of parameters within liquid samples typically generated in, for example, a large medical testing laboratory. The machine employs a unique probe and stirring rod assembly mounted at a slight angle with one another using rack and pinion assemblies so that the lower end of the probe and the lower end of the stirring rod are in very close proximity to one another. This feature allows the machine to be used in unusually small reaction cuvettes. The analysis machine also includes an onboard control sample so that the machine can be programmed to periodically calibrate its analyzing equipment during the course of normal operation.
    Type: Grant
    Filed: August 13, 1998
    Date of Patent: May 11, 1999
    Assignee: Beckman Instruments, Inc.
    Inventors: Richard P. Watts, David L. Goodale, Michael L. Bell, Dang M. Ngo, Songai Tu, Michael Tran
  • Patent number: 5891330
    Abstract: A system for treating human waste in remote or portable toilet facilities, including a holding tank that stores waste; a heat reservoir that receives waste from the holding tank, heats the waste to kill fecal coliform bacteria therein present, and routes the heated bacteria-free waste back through the holding tank. The holding tank maintains the heated bacteria-free waste separate from the contaminated waste but passes residual heat from the bacteria-free waste to the untreated waste. In one embodiment, a centrifuge receives the bacteria-free waste from the holding tank, separates the liquid waste from the solid waste, and discharges the liquid waste from the system. In one embodiment, the waste is pumped through the system to be heated in incremental portions.
    Type: Grant
    Filed: February 6, 1996
    Date of Patent: April 6, 1999
    Inventor: Nathan Morris
  • Patent number: 5885532
    Abstract: There is provided a burette apparatus having a delivery tube connecting a fluid bag to a burette assembly, via a fluid entry spigot formed in an end cap assembly of the burette assembly, the end cap assembly having a bypass spigot connected to the delivery tube and usually closed by clip, to allow an override for adding liquid to the burette. The end cap assembly closes the upper end of the transparent, cylindrical burette body, into which extends a stainless steel tube extension of the fluid entry spigot, the lower end of the burette body being closed by a lower closure assembly having a check valve and a drip chamber. An outlet tube passes from the drip chamber to the patient via regulating clamp. A float assembly is located in the burette body including an extension rod provided with a resilient cup adapted to engage the open end of the stainless steel tube extension.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: March 23, 1999
    Assignee: Noonbeach Pty Ltd.
    Inventors: Angelo John Maltabes, Godried Ferdinand Belser
  • Patent number: 5874049
    Abstract: A chemical mixing system for mixing ingredients at desired concentrations concentration within a qualification range. Batches of the mixed chemical are mixed in a relatively small mix vessel and transferred to a relatively large mix drum. The concentration of the chemical within the mix drum is measured by a concentration monitor. If the measured concentration of the chemical in the mix drum is within the qualification range, the batches of chemical in the mix vessel are mixed to the desired concentration. If the measured concentration of the chemical in the mix drum is below the qualification range, the batches of chemical in the mix vessel are mixed to a high concentration which is greater than the desired concentration. If the measured concentration of the chemical in the mix drum is above the qualification range, the batches of chemical in the mix vessel are mixed to a low concentration which is less than the desired concentration.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: February 23, 1999
    Assignee: Applied Chemical Solutions, Inc.
    Inventors: Edward T. Ferri, Jr., J. Tobin Geatz, Randall L. Green
  • Patent number: 5866426
    Abstract: A sensor detects when a probe contacts liquid in a container due to a change in frequency of a probe oscillator. The sensor can have its output compared to a reference level to determine the presence or absence of liquid wherein the reference level is changed to follow the output of the detector. In one embodiment, it can be determined that liquid has been contacted when a count has been reached several times in a row (the count being a function of the probe output and changeable). In another embodiment of the invention, it can be determined that liquid has been contacted when a count has been reached within a certain threshold several times in a row, while still having the reference count change to follow the probe output (regardless of the threshold). A digital counter can be provided to determine the frequency of the probe oscillator. A reference counter can also be provided to tune the count (frequency) from the probe oscillator counter to thereby compensate for drift.
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: February 2, 1999
    Assignee: Akzo Nobel N.V.
    Inventor: Stuart R. Ball
  • Patent number: 5851384
    Abstract: An apparatus for automatically delivering hemodialysis solution to a plurality of hemodialysis machines includes a plurality of supply tanks adapted to be fluidly communicated with a corresponding one of the hemodialysis machines. Each of the supply tanks has a bottom portion provided with a connecting port. A main tank contains the hemodialysis solution therein and is formed with an outlet port. A solution delivery system includes a main delivery pipe which has an inlet section connected to the outlet port of the main tank and provided with an electromagnetic delivery control valve and a delivery pump, and a plurality of main branch pipes. Each of the main branch pipes has an input portion connected fluidly to the main delivery pipe and an output portion connected fluidly to the connecting port of a respective one of the supply tanks. Each of the main branch pipes is provided with an electromagnetic main branch valve.
    Type: Grant
    Filed: June 20, 1996
    Date of Patent: December 22, 1998
    Inventor: Tsong-Nan Shen
  • Patent number: 5799877
    Abstract: A means and method for spraying liquid and gas onto and across a particulate bed includes a horizontal liquid distribution tray disposed over the bed containing a plurality of gas and liquid spray distributors extending through the tray. The distributors include separate gas and liquid conduits or pipes having an entrance on top and an exit below, with the exits proximate each other underneath the tray. The conduits are coaxial with a portion of the gas conduit surrounded by the liquid conduit to define an annular space between them for the liquid to flow downwardly through. The gas flows down through the gas conduit, exiting as a gas core surrounded by the downflowing liquid. The gas expands and contacts the surrounding liquid to spray it on the matter below. A liquid spray generating device is located below the gas and liquid exit. Siphon caps automatically provide pulse flow of the liquid.
    Type: Grant
    Filed: January 3, 1996
    Date of Patent: September 1, 1998
    Assignee: Exxon Research and Engineering Company
    Inventors: Ramesh Gupta, Jeffrey W. Frederick
  • Patent number: 5780306
    Abstract: The invention relates to a system for mixing a liquid with another liquid or a solid material by blowing a gas onto the surface of the liquid. The invention further relates to a system for implementing said method. Gas is blown onto the surface of the liquid from a distance which can be adjusted by determining the level of the liquid. A system of the invention, hence, comprises a device for blowing a gas onto the surface of a liquid and a device for detecting the level of a liquid.
    Type: Grant
    Filed: November 7, 1996
    Date of Patent: July 14, 1998
    Assignee: Boehringer Mannheim GmbH
    Inventors: Hans Schels, Karl-Heinz Mann, Horst Menzler, Leonhard Geissler, Georg Kuffer
  • Patent number: 5762804
    Abstract: Apparatus can prewet at least one filter with a supply of liquid and a supply of wetting agent. The apparatus has a container for holding at least the one filter. The apparatus also has a flow arrangement including a circulating subsystem and flushing subsystem. The circulating subsystem is connected to the container and the supply of wetting agent for: (a) circulating the wetting agent through the container during an initial phase, and (b) draining the wetting agent during a subsequent phase back to the supply of liquid. The flushing subsystem is connected to the container and is adapted to be coupled to the supply of liquid for flushing the liquid through the container. After loading a filter into the container, wetting agent is circulated through the container in the initial phase. Then the wetting agent is drained back to the supply of liquid in the subsequent phase. The liquid is flushed through the container without reopening the container, before removing the filter from the container.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: June 9, 1998
    Inventor: Martin J. Striefler
  • Patent number: 5695942
    Abstract: There is disclosed an automated apparatus and process for immunocytochemical staining of biological materials using ligand pairing. The apparatus includes an array of sample cells interconnected with reagent supply and drainage lines. Each cell encloses a fluid chamber into which a sample substrate is inserted. The face of the substrate onto which a biological sample is mounted faces into a fluid well. The cell includes a cell head having a chamber to receive therein a solid support matrix releasably containing a ligand to be contacted with the sample. The chamber in the cell head is in flow communication with the fluid well so that when the ligand is released from the matrix it flows into the fluid well thereby contacting the mounted biological sample. The ligand support matrix may be gelatin or wax.
    Type: Grant
    Filed: February 28, 1995
    Date of Patent: December 9, 1997
    Assignee: Histaggen Incorporated
    Inventors: A. James Farmilo, Ronald H. Stead
  • Patent number: 5693877
    Abstract: In order to prevent a catalyst for an internal combustion engine from experiencing decreased efficiency by deterioration after long time use of the catalyst, the decreased efficiency of the catalyst is determined, and the internal engine is controlled based on results of the determination so as to maintain high efficiency of the catalyst. The catalyst is installed in an exhaust pipe of the engine. Sensors for detecting conditions of exhaust gas both at a upstream side and a downstream side of the catalyst are provided, respectively. As for the sensor, for example, an oxygen sensor whose output varies stepwise at .lambda.=1, or a sensor whose output varies in proportion to air-fuel ratio can be used. Detected values of the sensors are taken into a control unit, catalyst efficiency and deteriorating degree of the catalyst are estimated by comparison of the detected values, and the engine is controlled so that the catalyst efficiency is maximized.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: December 2, 1997
    Assignee: Hitachi, Ltd.
    Inventors: Minoru Ohsuga, Mamoru Fujieda, Nobuo Kurihara
  • Patent number: 5672316
    Abstract: A microwave-heatable pressure reactor is provided for continuous or discontinuous treatment of liquid. The liquid is conveyed by means of a high-pressure pump in a pipeline which extends into a microwave-heatable zone of the pressure container into which it finally lets out through the free opening with a volume of pipe sufficient for the treatment of a desired quantity of liquid.
    Type: Grant
    Filed: March 7, 1995
    Date of Patent: September 30, 1997
    Inventor: Gunter Knapp
  • Patent number: 5670945
    Abstract: A self-monitoring hand-sanitizing station having a basin capable of holding an antiseptic solution to be situated near the entrance to a food handling area. A first proximity detector determines when an individual is approaching both the basin and the entrance. The basin contains a first moisture-proof switch and a second moisture-proof switch the activation of which switches must be done simultaneously; these switches are so situated that a user cannot accomplish such simultaneous activation with a single hand. A second proximity detector determines when an individual has passed beyond the basin toward the entrance.
    Type: Grant
    Filed: September 19, 1996
    Date of Patent: September 23, 1997
    Inventor: Alan R. Applonie
  • Patent number: 5665601
    Abstract: An aspirator/dispenser of liquid has a sensor for sensing contact with the liquid by the dispense vessel, which uses constant pressure air expelled out the tip of the dispense vessel. The sensor is improved in that the line of air pressure feeding into the vessel is vented in parallel with the vessel, to the atmosphere, so that the spike of pressure occurring when the vessel encounters the liquid, is released out the vent, rather than the vessel, thus avoiding bubble formation in the liquid.
    Type: Grant
    Filed: January 22, 1996
    Date of Patent: September 9, 1997
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventor: Kathleen Ellen Kilmer
  • Patent number: 5648727
    Abstract: A capacitive fluid level sensing pipette probe adapted to be used in an automated random access immunoassay analyzer is provided. The pipette probe comprises an elongated shaft having a conductive tip. An integrated circuit chip containing capacitive sensing circuitry is positioned on the pipette probe itself, or in very close proximity. With this arrangement, the sensing circuitry moves with the pipette probe as it is raised and lowered into and out of a vessel containing a liquid. Thus, errors associated with capacitance caused by flexing connector cables is eliminated. Flex tape wiring may be used to carry data from the capacitive sensing circuitry on the pipette probe to the processing board of the automated immunoassay analyzer.
    Type: Grant
    Filed: October 24, 1995
    Date of Patent: July 15, 1997
    Assignee: DPC Cirrus Inc.
    Inventors: William T. Tyberg, John W. Jones
  • Patent number: 5632960
    Abstract: A chemical mixing system for mixing ultra pure water and concentrated HF to a desired concentration within a qualification range. Batches of the mixed chemical are mixed in a relatively small mix vessel and transferred to a relatively large mix drum. The concentration of the chemical within the mix drum is measured by a concentration monitor. If the measured concentration of the chemical in the mix drum is within the qualification range, the batches of chemical in the mix vessel are mixed to the desired concentration. If the measured concentration of the chemical in the mix drum is below the qualification range, the batches of chemical in the mix vessel are mixed to a high concentration which is greater than the desired concentration. If the measured concentration of the chemical in the mix drum is above the qualification range, the batches of chemical in the mix vessel are mixed to a low concentration which is less than the desired concentration.
    Type: Grant
    Filed: November 7, 1995
    Date of Patent: May 27, 1997
    Assignee: Applied Chemical Solutions, Inc.
    Inventors: Edward T. Ferri, Jr., J. Tobin Geatz, Randall L. Green
  • Patent number: 5582798
    Abstract: A volume sensing device for determining the volume of liquid present in a standard plastic disposable pipette during a pipetting operation, which operation can be an aspiration or dispensing of liquid. The device comprises a cylinder made of hard synthetic material into which a disposable pipette is lowered at a predetermined velocity. The pipette which is being lowered into the cylinder holds an amount of liquid the volume of which the volume sensing device approximately determines. A pair of metal rings are coaxially mounted near the top end of the plastic cylinder. The pair of metal rings are preferably mounted in mating machined recesses of the plastic cylinder. This pair of metal rings is separated from each other by a small gap which forms the dielectric material of a capacitative circuit when the upper ring is connected to one portion of this circuit and the lower ring is connected to an other portion of the capacitative circuit.
    Type: Grant
    Filed: February 23, 1995
    Date of Patent: December 10, 1996
    Assignee: Cyberlab Inc.
    Inventor: Walter Meltzer
  • Patent number: 5550059
    Abstract: A fluid sensing pipette includes an outer conductive tube forming a first electrode and an inner conductive tube forming a second electrode. The inner conductive tube is disposed concentrically within the outer conductive tube. To insulate the inner conductive tube from the outer conductive tube, the inner conductive tube is coated with a thin, uniform, and consistent Parylene coating. A hydrophobic polymeric tube is disposed concentrically within the inner conductive tube to prevent cross-contamination between different biological samples aspirated into the pipette. The inner and outer conductive tubes are separately coupled to a level detection circuit which permits the pipette to detect entry of the pipette into a conductive fluid. The level detection circuit determines the impedance between the first and second electrodes and produces a control signal in response to the impedance falling below a predetermined threshold.
    Type: Grant
    Filed: December 16, 1994
    Date of Patent: August 27, 1996
    Assignee: Bayer Corporation
    Inventors: David L. Boger, Doraiswami Jaichandra, Donald L. Jaworski, Joseph E. Perry
  • Patent number: 5496447
    Abstract: A distilling apparatus for distillation of water, including a condensing chamber divided into an upper holding space for receiving water from a water source and a lower holding chamber for condensing steam into water, a heating chamber controlled to heat water from the upper holding space into steam and having a steam outlet connected to the lower holding space for guiding steam into the lower holding space for condensing, a hot water chamber, which receives condensed water from the lower holding space of the condensing chamber, and a cold water chamber, which receives distilled water from the hot water chamber and cools it down by an electronic cooler.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: March 5, 1996
    Inventor: Chin-Tu Wang
  • Patent number: 5494637
    Abstract: Endoscope washer and washing method for providing an endoscope washer which self-disinfects the washing basin and the fluid tubes automatically, each time an endoscope is washed and disinfected. The endoscope washer includes a washing and disinfecting basin having an endoscope holding portion for holding an endoscope and a washing fluid well for storing a washing fluid. The washer also including a water supply pipe, connected to a first water supply tube and a second water supply tube, for supplying a washing fluid to the endoscope holding portion and the washing fluid well. The washer also has a disinfectant tank for supplying a disinfectant to the endoscope holding portion and the washing fluid well through the water supply pipe, to provide a self-washing function for washing and disinfecting both the endoscope and the pipes, e.g., the water supply pipes, at the same time.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: February 27, 1996
    Assignee: Olympus America Inc.
    Inventor: David E. Barlow
  • Patent number: 5443792
    Abstract: A pipetting device contains a pipetting needle connected to metering device for transferring a volume of liquid from a primary vessel to a secondary vessel. Primary vessel and secondary vessels are disposed on the same or different vessel carrier units, and each vessel has a clearly defined position relative to the vessel carrier unit. Additionally, a device is provided for controlling conveyance of the pipetting needle in three directions. The controlling device controls the metering device and the conveyance device. The pipetting device independently determines coordinates of the pipetting positions for each vessel carrier unit. For each vessel carrier unit at least one reference member, which is part of the vessel carrying unit or is directly and permanently connected thereto, may be provided. These vessel carrier units have flat surfaces which are accessible to sensing the pipetting needle.
    Type: Grant
    Filed: October 19, 1994
    Date of Patent: August 22, 1995
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Jurg Buhler
  • Patent number: 5437842
    Abstract: A foam control system is provided for eliminating foam in a process fluid system, such as foam generated in the course of blanching steps and the like involving processing of potatoes or other food products. The foam control system includes one or more capacitive type proximity probes for detecting the presence of foam in a corresponding number of process fluid systems or tanks, and for automatically supplying a spray of a selected defoamer agent to the tank. The defoamer agent spray is supplied to the tank for a selected time interval, with a portion of the spray being directed at the associated detector probe to insure clearing of foam from the probe.
    Type: Grant
    Filed: March 28, 1991
    Date of Patent: August 1, 1995
    Assignee: J. R. Simplot Company
    Inventors: Richard B. Jensen, H. Jeff Kronenberg
  • Patent number: 5387396
    Abstract: With a view to improving the heat transfer in exothermic reactions and simplifying the construction of the cooling system of the reactor, in particular a stirrer reactor, vertical boiling tubes which are sealed at the bottom are provided, above which is arranged a condensate collecting and liquid distributing chamber in which a sufficient layer of cooling liquid is constantly maintained by means of a liquid level regulator. Cooling fluid and the vapor produced flow in direct contact with each other as they are carried in counter current through the boiling tubes which have only single walls. The vapor passes through the layer of cooling fluid and is continuously discharged and preferably recovered. The condensate is preferably returned to the cooling system.
    Type: Grant
    Filed: May 22, 1991
    Date of Patent: February 7, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hermann Dallmeyer, Harald Stein
  • Patent number: 5380485
    Abstract: Apparatus for conducting and controlling chemical reactions, wherein idealistic reaction conditions are achieved automatically for chemical reaction systems in a reaction vessel. The apparatus includes a pH-sensor, a temperature sensor and a vacuum sensor in the reaction vessel. The apparatus also includes electronic scales to measure the weight change in additive liquid containers linked with liquid flow mechanisms to supply additive liquids into the reaction vessel. A cooling mechanism is provided to cool the reaction vessel and a vacuum mechanism is provided to degas the inner space of the reaction vessel. A CPU is arranged to control the liquid flow mechanisms, the cooling mechanism and the vacuum mechanism based on calculated values derived from signals issued by the sensors and the scales.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: January 10, 1995
    Assignee: Todoroki Sangyo Kabushiki Kaisha
    Inventors: Shizuo Takahashi, Takao Kobayashi
  • Patent number: 5352415
    Abstract: A novel control system is provided to control the liquid levels in a reactor-flasher combination used particularly for the carbonylation of methanol to acetic acid. Liquid level control is achieved by proportional controllers or other controllers which do not continuously seek zero off-set from the desired level and which proportionally change the liquid flow rates from the respective reactor and flasher. An adjustment can be made to the level controllers to change the liquid flow rates by a function generator which adjusts the flow rate, according to an empirically derived function which correlates changes in methanol feed rate to liquid flow rates from the reactor and flasher.
    Type: Grant
    Filed: September 29, 1993
    Date of Patent: October 4, 1994
    Assignee: Hoechst Celanese Corporation
    Inventor: Shinya Ochiai
  • Patent number: 5312594
    Abstract: A method and apparatus for treating nuisance odor streams is provided. One embodiment of the invention is directed to a method and apparatus in which deodorizing chemical agents are applied to an evaporative reaction pack situated within a gas chamber having an air stream running therethrough. The evaporative reaction pack provides a reaction zone within which the chemical agent is evaporated to facilitate a gas-gas or vapor phase interaction between the chemical agent and odoriferous compounds contained in the air stream. Another aspect of the present invention relates to a method and apparatus for batch processing of sewage within a wet well to prevent the formation of undesired compounds. In one embodiment, a predetermined amount of chemical agent, sufficient for treating the amount of sewage that the well can hold, is added to an evacuated wet well in coordination with the pumping of sewage from the wet well.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: May 17, 1994
    Assignee: Nutech Environmental Corp.
    Inventors: Jon D. Heller, Kenneth J. Heller, Timothy Reeves
  • Patent number: 5275951
    Abstract: An apparatus is provided which includes a reaction cartridge having a plurality of reaction wells having different reagents disposed thereon, at least one well adapted to receive a sample, a well containing particles adapted to bind to the sample and which have the capability of being separated from cells which are not bound to the separation particles and at least one fluorophore adapted to bind to a specific type of cell in the sample, and a wash area adapted for washing a probe. An image forming device is provided to detect images which indicate whether specific reactions have occurred in each of the reaction wells. The apparatus also includes a mechanism for dispensing and aspirating liquids including a mechanism for detecting liquid levels. The device further includes logic for analyzing the information received from the image detection apparatus and processing the information to generate a visual indication of the results of the assays being performed.
    Type: Grant
    Filed: September 3, 1992
    Date of Patent: January 4, 1994
    Assignee: Abbott Laboratories
    Inventors: Herbert S. Chow, John J. Kotlarik, Mieczyslaw Wroblewski, Thomas J. Wilson, Jimmy D. McCoy
  • Patent number: 5271902
    Abstract: A quantitative liquid sampling instrument comprises a main body of a pipet device which includes a pipet tip having an opening at its lower end for sucking and discharging a liquid. The pipet tip being in a shape of a tube shell having a cavity for holding a liquid sucked therein through the opening and being made of a transparent or semi-transparent material. The main body further comprising a device for applying a gas pressure for sucking or discharging the liquid to or from the inside of the cavity of the pipet tip.
    Type: Grant
    Filed: December 2, 1991
    Date of Patent: December 21, 1993
    Assignee: Tosoh Corporation
    Inventors: Toshiaki Sakka, Yukio Mitsuhisa
  • Patent number: 5254244
    Abstract: A mixer-settler is provided which is modulatable and permits use, manipulation and maintenance within a tight, shielded enclosure using a telemanipulator. The mixer-settler is constituted by several modules (M1, M2, M3), which can be reciprocally dismantled by using tight connecting means (19, 20, 21). The inlets and outlets (17, 18) for the heavy and light phases are located on the front face (40) of each module. Regulating members (9, 10, 11) issue onto the upper surface of each module close to the front face (40). Preferably, shield windows (12) make it possible in each case to see the interphase of a stage comprising a mixing chamber (1) and a settling chamber (2). This is completed by a motorization assembly (3) placed above the module. Application to the treatment of radioactive liquids.
    Type: Grant
    Filed: August 20, 1992
    Date of Patent: October 19, 1993
    Assignee: Cogema Compagnie Generale des Matieres Nucleaires
    Inventor: Rodolph Chomel