Abstract: There is described a heating system for independently heating at least one sample recipient containing a sample, the sample recipient provided in a sample holder, comprising: a heating chamber having at least one opening and adapted to receive the sample holder; at least one microwave generator for generating microwaves; at least one microwave applicator inside the heating chamber connected to the at least one microwave generator, the at least one microwave applicator comprising an oven cavity portion for creating a mini microwave cavity around a single sample recipient in the sample holder, and for applying microwaves generated by the at least one microwave generator directly to the single sample recipient; and a control unit for controlling the at least one microwave generator.

Abstract: The invention relates to a closure system for a holder for a reaction vessel in an automatic analysis apparatus. The closure system comprises a lid secured movably on a retainer element, wherein the lid closes an opening of the holder in a closed position and opens it in an open position. The closure system further comprises a restoring element, which is designed in such a way that, depending on the position of the lid, it exerts a restoring force in the direction of the closed position or of the open position.

Abstract: A digital microfluidics system manipulates samples in liquid droplets within disposable cartridges and has disposable cartridges each with a bottom layer, a top layer and a gap therebetween. A base unit with cartridge accommodation sites and at least one electrode array with electrodes works with a cover plate at the sites and a control unit for controlling selection of the electrodes and for providing them with voltage pulses for manipulating liquid droplets within the cartridges by electrowetting. The cover plate has an electrically conductive material that extends parallel to the array. A selection of disposable cartridges and a method for manipulating samples in liquid droplets that adhere to a hydrophobic surface can be used with the system.

Abstract: There is provided a sample processing apparatus capable of detecting the push-up type sample container including a recess on the outer side of the bottom portion of the container and performing an appropriate sample processing while alleviating the load of the user with a simple configuration.

Abstract: An apparatus for holding a contact lens during in vitro testing includes a first support member, a second support member, an alignment rod, and a cage member. The first support member includes a first end cap and a body portion. The body portion includes grooves formed in a lateral surface extending from the first end cap. The alignment rod is configured for interconnecting the body portion and a second end cap of the second support member. The cage member is positionable about the body portion between the first and second end caps, and includes an inner surface, an outer surface, and a plurality of openings between the inner surface and the outer surface. The inner surface and the lateral surface cooperatively define an annular space therebetween and a plurality of fluid flow paths between the inner space and the openings. The annular space is configured for receiving the contact lens.

Abstract: A container for storing a biological sample is disclosed. The container includes a first chamber having a sidewall extending between an open end and a closed end, defining a first chamber interior adapted to receive a sample holder therein. The container also includes a second chamber having a sidewall extending between an open end and a closed end, defining a second chamber interior adapted to subsequently receive the sample holder therein. The second chamber interior is in fluid isolation from the first chamber interior. A removable closure encloses at least one of the open end of the first chamber and the open end of the second chamber while the sample holder is disposed within one of the first chamber interior and the second chamber interior. A first fluid may be disposed within the first chamber interior, and a second different fluid may be disposed within the second chamber interior.

Abstract: Embodiments of the invention relate to a clinical instrument analyzer system for the automatic analysis of patient samples. In one embodiment, the analyzer may be used to analyze bodily fluid samples, such as blood, plasma, serum, urine or cerebrospinal fluid, for example. Embodiments of the invention relate to an apparatus and method, for example, an immunoassay method, for separating out target molecules in a magnetic field and then analyzing those target molecules with a luminometer.

Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.

Abstract: The invention discloses a sample-support element for ultra-high vacuums comprising a main chamber and a supplementary chamber for the sample holder and the heating/cooling elements, which is pumped by a related pump line. This enables the reduction or total elimination of the negative effect related to the alteration of the residual atmosphere in ultra-high vacuums resulting from heating or cooling the surfaces of the sample holder.

Abstract: A thermal cycling instrument for PCR and other reactions performed on multiple samples with temperature changes between sequential stages in the reaction procedure is supplied with a thermal block to provide rapid changes and close control over the temperature in each sample vessel and a pressure plate incorporated into a motorized lid that detects anomalies in the reaction vessels or in their positioning over the thermal block, and automatically adjusts the plate position to achieve an even force distribution over the sample vessels.

Abstract: Disclosed are compositions, devices, and methods for loading molecules of interest onto a substrate by contacting beads having molecules of interest attached to them with the substrate, for example by providing a field that brings the beads into proximity or contact with the substrate and moves the beads with respect to the substrate. Such molecules of interest can be deposited onto substrates for single-molecule analysis.

Abstract: The invention relates to a rotatable device (1) for transporting reaction vessels in an automatic analysis apparatus, said device (1) comprising a circular base plate (16), and a number of holders (2) which are connected to the base plate (16), are preferably made of a plastic and comprise the receiving positions (4, 6) for the reaction vessels.

Abstract: Multiplex binding assay assemblies are disclosed. The assemblies generally include at least one assay bar that includes a top side, a bottom side, and at least one well accessible from the top side of the assay bar. Each well includes a side surface, a bottom surface, an open top end, and at least one secondary container, with each secondary container including a capillary tube that (i) begins at a location within an interior volume of the well and (ii) ends at a location beneath the bottom surface of the assay bar. The assemblies further include a dispenser bar that is adapted to be positioned adjacent to the top side of the assay bar, which includes one or more reservoirs that are configured to provide one or more reagents to the at least one secondary container located in each well of the assay bar.

Abstract: Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In one embodiment, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge.

Abstract: An adapter for use with a hand-held electronic device for use in detecting the optical properties of a sample. The adapter includes a backing plate having an integral surface that secures the adapter to the electronic device. The adapter also includes a sample housing having a sample holder and a cap. The sample holder is configured to receive the placement of a sample and/or a sample vessel. The backing plate includes an orifice that allows the passage of light from the sample to the detector of the electronic device. The backing plate may also include another orifice that allows for light emitted from an emitter of the electronic device to enter into the sample holder. The sample holder may also include reflective surfaces that direct light to/from the sample as well as filters that filter the wavelength of light sent to sample and/or detected by the detector.

Abstract: The present invention relates to a test specimen holding device for inspecting a sterilization- and/or cleaning process. The holding device comprises: a substantially spherically shaped body comprising at least one through opening for a cleaning- and/or sterilization agent to enter the body, at least one receptacle to receive and/or to keep at least one test specimen inside the body.

Abstract: A microstructured measurement chip (1) for optical measurement of properties of artificial or biological membranes (40), having a lower, translucent support layer (10) and at least one non-translucent main layer (20) disposed on top of the former, which layer has depressions (30) configured as measurement chambers, having an upper opening (25) and one or multiple inner side walls (26). In order to improve the measurement chip (1) in such a manner that biological systems can be measured with greater measurement accuracy and higher throughput, it is proposed that the side wall or the side walls (26) of the measurement chambers (30) have depressions (27) and/or elevations (28). The invention furthermore relates to a holder (200) for the measurement chips (1) as well as to a method for the production of the measurement chips (1) from a silicon wafer (300).

Abstract: A protective cap 2 is engaged with a latch 10 of a diluent container 5 so as to fix the diluent container 5 at a liquid holding position of a diluent container containing section 11. The engagement is released when the protective cap 2 is set to an open position against the engagement so as to expose an inlet 13. When the protective cap 2 is shifted from the open position to a closed position, the protective cap 2 pushes the diluent container 5 into a liquid discharge position. Thus, it is possible to preserve a diluent for a long period of time and to easily open the diluent container 5 without having to complicate the structure of an analysis apparatus.

Abstract: A clamp for an Erlenmeyer flask or other laboratory containers or racks uses nickel-coated, rare earth magnets to secure the clamp to a platform for a laboratory shaker. The base of the clamp has downwardly extending positioning bosses that seat in holes or indentations on the shaker platform to prevent horizontal sliding of the clamp when the shaker is in use. A removable and replaceable, elastomeric cover for the base of the flask clamp provides cushioning and prevents spinning of the flask when the shaker is in use.

Abstract: Apparatus (2) for testing a liquid specimen, which apparatus (2) comprises a container (4) for the liquid specimen, a response chart (6) which is operable in response to contact with the liquid specimen, and a result chart (8) for use with the response chart (6), and the apparatus (2) being such that: (i) the container (4) comprises a body portion (10), a lid (12), a test chamber (14), and openable means (16) which is adapted to be broken in order to allow the liquid specimen to pass from the body portion (10) into the test chamber (14); (ii) the response chart (6) comprises response portions (18) which are contacted by the liquid specimen, which become differently colored to indicate different characteristics present in the liquid specimen, and which are read at predetermined time intervals; (iii) the result chart (8) comprises result sectors (22), each result sector (22) is for indicating the result of a different test for the liquid specimen, and each result sector (22) has a plurality of differently color

Abstract: Laboratory spatula having stalk regions with a hollow first end and a hollow second end and at manipulating regions may be used for collecting, transporting or storing a material. A manipulating region may be configured as a shovel region, a scoop region, a whisk region, a punch region, a sieve region, a loop region, a cutting edge, a spreading region, a grinding region, a hook region, a scraper region, a tweezer region, a grasper region, or a pick region. The spatula may be lightweight and disposable, and may be any appropriate size including micro size, a regular size, or a macro size. The spatula may also have an anti-stick surface. The spatula may be calibrated, and may include calibration marks or additional features.

Abstract: Described are devices for retaining a nonporous substrate, as well as methods for their use, the devices comprising a housing for receiving the nonporous substrate, a removable well insert attached to the housing and adjacently coplanar to the substrate, the well insert having at least one opening that, together with the substrate, defines a well, and means for exerting a force against the substrate such that the substrate engages the well insert with sufficient force to attain a fluid-tight seal in the well.

Abstract: A device for the photometric examination of samples has a sample-holder apparatus for at least two sample vessels, and a measuring apparatus and a moveable apparatus. The sample-holder apparatus is designed to be stationary, and the measuring apparatus is arranged on the moveable apparatus such that it can be displaced by means of the moveable apparatus.

Abstract: Multiplex binding assay assemblies are disclosed. The assemblies include at least one assay bar that has a top side, a bottom side, and at least one well accessible from the top side of the assay bar, with each well including a side surface, a bottom surface, an open top end. Each well also includes at least one secondary container, with each secondary container including a capillary tube that (i) begins at a location within an interior volume of the well and (ii) ends at a location beneath the bottom side of the assay bar. The assemblies further include a guiding track, which includes a set of two rails, with each rail having its own separate groove. Such grooves are configured to run parallel to each other with a distance between such grooves, with a first groove configured to receive a protruding element (or an end) of a first side of the assay bar, and a second groove configured to receive a protruding element (or an end) of a second side of the assay bar.

Abstract: The invention provides an apparatus and a method of processing a biological and/or chemical sample in a liquid droplet. The apparatus comprises a processing compartment, which is defined by a reservoir and an immobilization member. The processing compartment is further adapted to accommodate a medium, which is immiscible with the liquid droplet, and of a lower surface energy than the liquid of the liquid droplet. The reservoir is defined by a circumferential wall and a base. The immobilization member is arranged within the reservoir and comprises a surface that is patterned in such a way that it comprises at least one predefined immobilization area. The predefined immobilization area within the patterned surface is of a higher surface energy than the medium. The liquid droplet is disposed onto the predefined immobilization area, whereby the liquid droplet is immobilized thereon via hydrophilic-hydrophilic or hydrophobic-hydrophobic interactions.

Abstract: Container holder suitable for receiving and holding a container, said container holder comprising a base frame for receiving said container, and at least one supporting member; characterized in that said at least one supporting member is pivotally mounted on the base frame such as to pivot between first position in the absence of container and a second position when the container is received in the base frame; the container holder further comprises a displaceable element movably mounted in the base frame such as to move along a predetermined distance that is proportional to the pivotal angle of said at least one supporting member; and in that a displacement sensor responsive to the predetermined distance of the displaceable element such as to detect at least determine its diameter when received in the container holder.

Abstract: The present invention relates to a vial (10) for receiving goods (30) in a leak-proof arrangement, with a body (14) and a cap (12) connected via a hinge (16), the vial including a mold (26) for receiving lamellar goods (30), with the mold having a height which is less than the length of lamellar goods wherein a cavity (40) is formed between said mold receiving the stack of lamellar goods and the container body which cavity (40) receives desiccant material (44).

Abstract: A biotip according to an embodiment of the invention moves a reaction mixture along a longitudinal direction under the force of gravity. The biotip includes a chamber formed of a transparent material and filled with a liquid having a smaller specific gravity than the reaction mixture and immiscible with the reaction mixture, and a seal that seals the chamber. The liquid has a volume resistivity of greater than 0 ?·cm and 5×1013 ?·cm or less.

Abstract: Provided is a rack transport system that horizontally slides a rack tray holding and storing a plurality of specimen containers, allowing the rack tray to be safely placed on a rack tray set section. For this purpose, a rack transport system (8) using a rack tray (10) having a rack dropout-preventing mechanism (10b) includes a rack tray set section (8A) that has a lock canceling mechanism (8i) of the rack dropout-preventing mechanism and on which the rack tray that arranges and holds a plurality of racks (9) supporting a plurality of specimen containers (9a) is placed, and a projection section (8h) serving as a lock canceling button of the rack dropout-preventing mechanism is formed at a position where the rack tray that holds and stores the plurality of racks supporting the plurality of specimen containers is slid to be able to be set in the rack tray set section.

Abstract: Magnetic microplate assemblies are disclosed for assaying of biological activated magnetic particles from a supernatant. The assemblies include a magnetic microplate holder and a microplate including a plurality of wells for retaining the magnetic particles. The microplate holder includes a plurality of magnets for attracting the magnetic particles to the wells and a plurality of detents for securing the microplate in the holder. The detents allow the microplate to be tightly retained in the holder when the assembly is turned over to discard supernatant and wash buffer applied to rinse supernatant from the magnetic particles.

Abstract: A plate handling system for a sampling device with a drawtube that includes a vertical actuation system that adjusts the vertical distance between the drawtube and a sample tray, a horizontal linkage system that positions a sample tray in a horizontal plane, and a drive system that drives the rotational motion of the horizontal linkage system. The horizontal linkage system includes a base arm that rotates about a base joint, and a sample arm that rotates about a sample arm joint on the base arm.

Abstract: An apparatus for irradiating a liquid sample with acoustic energy to generate cavitation in the liquid sample is provided. The apparatus includes a source and is adapted to receive a cartridge in such a way, that the apparatus focuses the HIFU waves emitted from the source onto a liquid air interface that is present within the cartridge. This focusing is performed when the cartridge is inserted into a receiving section of the apparatus.

Abstract: The present invention concerns a breakable multi-specimen storage vessel. The vessel comprises a tubular container comprising a lower end and an upper end. At least said upper end has an open end opening. The length of said container is continuously formed and provided with break portions at predetermined positions alongside thereof. Said container is adapted to be broken into a plurality of specimens. Further, an external surface of said container may be provided with a screw thread. Said screw thread is provided extending longitudinally along substantially the entire length of said tubular container and said internal surface is substantially smooth. The invention further relates to a break tool for breaking off specimens from a multi-specimen storage vessel such as a storage vessel according to the invention.

Abstract: A chemical analyzer, a method for sample-based analysis, a device for handling cuvette assemblies including a rotatable incubator with at least one curved opening for receiving a new cuvette assembly, an analyzer arranged around the incubator for analyzing contents of the new cuvette assembly, and a loading device adapted to carry the new cuvette assembly while initially being aligned in a straight manner before being loaded. The loading device includes a feed funnel having a first end for receiving the new cuvette assembly initially aligned in the straight manner into the feed funnel, and a second end for feeding the new cuvette assembly into the at least one curved opening, the second end having a curvature which corresponds to the curvature of the curved opening, the second end for bending the initially straight new cuvette assembly and fitting the new cuvette assembly into the at least one curved opening.

Abstract: The invention relates to a device for the earning out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterised by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.

Abstract: In one aspect, a diagnostic test system includes a receptacle, optical detectors, and a logic circuit. Each of the optical detectors has a corresponding view in the receptacle and produces an electrical signal at a respective detector output in response to light from the corresponding view. The logic circuit includes logic inputs that are respectively coupled to the detector outputs and that produce an output logic signal corresponding to a logical combination of signals received at the logic inputs. In another aspect, respective detection signals are produced in response to light received from respective ones of multiple views of the test strip, and at least one output logic signal corresponding to a respective logical combination of the detection signals is generated.

Abstract: Provided is an immobilization device for fitting a connecting member of a chip and a connecting member of a cover together, where a spatial clearance between the chip and cover is small. The immobilization device includes a substrate (102), a cover means (101) including a fitting means to fit with a chip (103) placed on the substrate (102), a rotating arm means (201) rotatably joined to a first joining means (301) of the substrate (102) and to a second joining means (302) of the cover means (101), and a parallel maintaining means (203) for fitting the fitting means and the chip (103) together with the fitting means and the chip (103) maintained in substantially parallel by the first joining means (301) or the second joining means (302) moving along a chip surface or a plane parallel to the chip surface. The fitting means rotates freely against the chip (103).

Abstract: A device for the accommodation of a solid in a measuring cell (24), in which the release of the solid can be determined in a solution medium flowing through the measuring cell (24), has an insert (1) which can be introduced into the measuring cell (24) and which has a recess for the accommodation of a pressed disc (31). The recess for the accommodation of the pressed disc (31) is arranged on a side (16) of the insert (1) which faces the inflowing solution medium. A wall surface (32) of the insert (1) which surrounds the recess for the accommodation of the pressed disc (31) is tilted in the flow direction, so that the inflowing solution medium is transported laterally away from the pressed disc (31). The insert (1) has a housing (2) with a hole (3) through it, a sleeve (4) for the accommodation of the pressed disc (31), which can be accommodated in the hole (3), and a closure device (10). The housing (2) and the closure device (10) essentially consist of a plastic material and the sleeve (4) consists of metal.

Abstract: The disclosure relates to a cassette, frame and mold for holding a tissue sample during an embedding and mircotoming process, and related methods. The cassette is sectionable in a microtome and includes a body with a bottom wall and a plurality of side walls. First and second side walls are generally V-shaped to present an apex of the “V” to the microtome blade. A lid of the cassette is stiffer than the bottom wall of the cassette to assist with positioning the tissue sample. The side walls of the cassette are perforated so as to significantly reduce the amount of cassette material that must be cut by the microtome blade. In one embodiment, to additionally reduce blade wear the ribs on one side wall are offset lengthwise relative to the ribs on an opposite side wall. An upper flange of the cassette includes depressions configured to register with detents in the frame.

Abstract: The present invention relates to the use of a container, made of an inorganic additive containing plastic material, for reducing physical/chemical interaction between the container and an oil, fat and/or wax containing formulation contained therein.

Abstract: A micro vial assembly for performing microwave-assisted chemical reactions on small reaction mixture volumes is disclosed, wherein a reaction vessel (10) is sealed through a diaphragm (30) that is capped over an open end of the reaction vessel. The reaction vessel mouths in an end plane of a sleeve (20) surrounding the reaction vessel, the diaphragm being clamped for sealing the open end of the vessel by means of a cap (40) which is secured to the sleeve. The sleeve provides a radial extension of the reaction vessel in order to bridge the radial distance between a wall of the reaction vessel and other components in a system for performing microwave-assisted chemical reactions.

Abstract: A rack used in a device for preparing or analyzing a sample is provided. The rack includes, but is not limited to, a base, a plurality of walls extending from the base, a plate extending between the plurality of walls opposite the base, and a wireless power conductor. The plate includes, but is not limited to, a plurality of cavities. Each cavity of the plurality of cavities is configured to hold a receptacle that is configured to hold a liquid for analysis of a sample or each cavity of the plurality of cavities is configured to hold the liquid for analysis of the sample. The wireless power conductor is mounted to the base and is configured to receive energy by electromagnetic induction from a second wireless power conductor.

Abstract: Magnetic microplate assemblies are disclosed for assaying of biological activated magnetic particles from a supernatant. The assemblies include a magnetic microplate holder and a microplate including a plurality of wells for retaining the magnetic particles. The microplate holder includes a plurality of magnets for attracting the magnetic particles to the wells and a plurality of detents for securing the microplate in the holder. The detents allow the microplate to be tightly retained in the holder when the assembly is turned over to discard supernatant and wash buffer applied to rinse supernatant from the magnetic particles.

Abstract: In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a base with first and second ends, a concave recess in the first end, a second end receiving surface, and a sidewall extending between the ends. An electrode may be provided on the receiving surface with an electrochemically-active region coupled to the electrode. A conductor in electrical contact with the electrode may extend along the sidewall and may be adapted to be in electrical contact with a first contact of an analyte meter. Manufacturing methods and systems utilizing and dispensing the analyte sensors are provided, as are numerous other aspects.

Abstract: A decapping/recapping device for removing closures from sample tubes and for reclosing sample tubes with the same closures is presented. The device comprises individual closure holders, each holder comprising a passive closure gripper for holding a closure, at least one actuator for actuating the passive closure gripper when removing a closure from a tube or reclosing a tube with its respective closure and at least one tube gripper cooperating with the at least one actuator for biasing a tube and its closure away from each other when removing the closure and for biasing the tube and its closure towards each other when reclosing the tube. One actuator is coupled to one passive closure gripper of a closure holder when removing a closure from a tube or when reclosing a tube with its respective closure and is decoupled from a passive closure gripper when the closure holder is holding a closure.

Abstract: The present invention relates to a reagent slot, a sample tray and a combination kit used in biochemical test; this reagent slot is used to be mounted in the sample tray. Specifically, the reagent slot has a main frame which has plural holding holes, and the sample tray includes a plate portion, which is equipped with plural inserting holes and plural inserting slots, and a support portion which is used to support the plate portion.

Abstract: A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored in a specimen container (150) and sampling it in a first container (153), a step for optically measuring the specimen in the first container, a step for sampling the specimen in a second container (154) and preparing a specimen for measurement by mixing the specimen with a reagent in the second container, and a step for analyzing the specimen for measurement according to the results of the optical measurement of the specimen.

Abstract: A device for holding a medical test strip is provided. The device comprises a receiving casing having an opening for receiving the medical test strip and a first stopping portion protruding from an upper surface of the receiving casing; an ejection base having a cover and a pusher beneath the cover, the cover downwardly extending a second stopping portion for sliding against the upper surface of the receiving casing; and an elastic member located between the receiving casing and the ejection base. When the pusher moves toward the opening by an external force to eject the test strip from the opening, the elastic member is compressed and the second stopping portion slides away from the first stopping portion. When the external force disappears, the second stopping portion slides toward the first stopping portion by a resilient force of the elastic member until the first stopping portion and the second stopping portion are engaged.

Abstract: The present invention relates generally to the field of analysis, for example biological analysis.

Abstract: A filtration syringe having at least a first and second chamber separated by a fluid permeable membrane, which may be selectively permeable to solids of a certain size, allows aspirated particle-filled fluid to be filtered within the syringe. A centrifuge tube apparatus is also provided for centrifuging a sample collected in a syringe, the apparatus comprising: a syringe comprising at one end a narrowed outlet and means for connection to a needle and at the opposing end a partially inserted syringe plunger; and a syringe holder having an interior for accepting the syringe, wherein the interior comprises at least one ledge for resting the syringe in an inverted position within the holder to prevent further insertion of the plunger during centrifugation, further wherein the syringe holder is sized for insertion in a centrifuge rotor.