Ammonia, Amine, Or Derivative Thereof (e.g., Urea, Etc.) Patents (Class 424/54)
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Patent number: 9345655Abstract: Aqueous oral compositions containing a cationic steroidal compound and a quaternary ammonium compound are suitable for treating conditions of the oral cavity.Type: GrantFiled: December 21, 2011Date of Patent: May 24, 2016Assignee: BRIGHAM YOUNG UNIVERSITYInventors: Joe Vazquez, Dandan Chen, Harsh M. Trivedi, Ammanuel Mehreteab, Laurence Du-Thumm, Gregory Szewzyk, Zhigang Hao
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Patent number: 9320696Abstract: Described herein are compositions comprising a MMP-13 inhibitor, and methods of using the same.Type: GrantFiled: October 2, 2014Date of Patent: April 26, 2016Assignee: Colgate-Palmolive CompanyInventors: Wei Wang, Virginia Barnes, Harsh M. Trivedi, Tao Xu
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Patent number: 9265712Abstract: A dental bleaching composition comprises a dental bleaching agent, polyvinylpyrrolidone, and at least 0.1% water. The bleaching composition may include a liquid component, flavoring agent, basic substance, and/or desensitizing agent as desired. Polyvinylpyrrolidone avoids acid etching and chelation of teeth that were problematic in bleaches using carbomer as a thickener. A delivery system for delivering the bleaching composition comprises the aforementioned dental bleaching composition in combination with a moisture-resistant barrier layer such as a dental tray or a flexible strip of material.Type: GrantFiled: September 22, 2014Date of Patent: February 23, 2016Assignee: Ultradent Products, Inc.Inventor: Tianming Chen
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Patent number: 9254255Abstract: A dental care product comprises an orally acceptable carrier or excipient, and a bacterial resistance copolymer, which comprises a zwitterionic block and a charged anchoring block, wherein the anchoring block binds to tooth surfaces by electrostatic attraction, and the zwitterionic block extends outwardly to reduce the attachment of bacteria to tooth surfaces.Type: GrantFiled: January 23, 2015Date of Patent: February 9, 2016Assignee: CHUNG-YUAN CHRISTIAN UNIVERSITYInventors: Yung Chang, Yu-Ju Shih, Bor-Shiunn Lee, Da-Ming Wang, Juin-Yih Lai
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Patent number: 9241885Abstract: Disclosed are oral care compositions, including therapeutic rinses, especially mouthrinses and methods of use to provide significantly enhanced antimicrobial activity, thereby reducing oral bacteria and promoting overall oral health. The present compositions are formulated to deliver increased bioavailable levels of cationic antimicrobials, particularly quaternary ammonium compounds such as cetylpyridinium chloride (CPC) and are useful for preventing and treating diseases or conditions of the oral cavity including dental plaque, caries, gingivitis, periodontal disease and breath malodor. The present compositions are formulated to be essentially free of anionic, nonionic or amphoteric surfactants, which have been found to have a negative effect on bioavailability of the quaternary ammonium compounds and thus, their antimicrobial efficacy.Type: GrantFiled: January 18, 2005Date of Patent: January 26, 2016Assignee: THE PROCTER & GAMBLE COMPANYInventors: Rebecca Lynn Roberge, Andrew Lee Wong
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Patent number: 9144578Abstract: The invention relates to a fixed-dose association of phytate and zinc in synergic proportions for use in the treatment of crystallization of hydroxyapatite. Advantageously, said association is in a molar ratio between the phytate and the zinc exceeding 4:1. The invention also relates to the use of said association for manufacturing a drug for the treatment, prophylaxis and/or prevention crystallization of hydroxyapatite in humans.Type: GrantFiled: February 19, 2013Date of Patent: September 29, 2015Assignee: Universitat de les Illes BalearsInventors: Felix Grases Freixedas, Joan Perello Bestard, Bernat Isern Amengual, Pilar Sanchis Cortes, Rafael M. Prieto Almirall, Antonia Costa Bauza
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Patent number: 9125899Abstract: The present invention relates to molecules which function as modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases (e.g. Rac, Cdc42 and Rho GTPases) and their use to treat diseases, including cancers (including solid tumors-medulloblastoma, ovarian, breast, head and neck, testicular, prostate among others and hematologic malignancies-B cell lymphoma, where these GTPases are overexpressed or hyperactivated), sporadic and genetic diseases where activation of Rho GTPases plays a pivotal role (Menkes disease, rheumatoid arthritis, atherosclerosis, diabetes (type 1), Huntington's disease and Alzheimer's disease) which are mediated through these proteins. Compounds according to the present invention may also be used as a therapy for the treatment of Entamoeba spp. or Acanthamoeba spp, infections, especially including Entamoeba histolytica.Type: GrantFiled: June 16, 2011Date of Patent: September 8, 2015Assignee: STC.UNMInventors: Angela-Wandinger Ness, Laurie Hudson, Larry Sklar, Zurab Surviladze, Tudor Oprea
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Publication number: 20150147361Abstract: The invention relates to the use of sphingosine based compounds, in particular phytosphingosine compounds, in the protection of hydroxyapatite containing materials such as teeth and bone. Such compounds are especially useful in the treatment and prevention of dental caries, dental erosion, dentine hypersensitivity and tartar (dental calculus) formation. Methods and devices are also provided for preventing biofilm formation using sphingosine based compounds. Compositions comprising sphingosine based compounds are also provided.Type: ApplicationFiled: April 26, 2013Publication date: May 28, 2015Applicant: Stichting VU-VUmcInventors: Floris Jacob Bikker, Engelmundus Cornelis Ignatius Veerman, Marianne Valentijn-Benz, Willem Van'T Hof
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Publication number: 20150132347Abstract: Oral formulations are provided for prevention and treatment of adverse oral conditions such as gingivitis, periodontal disease, removal of calculus to improve dental hygiene, and control of dental plaque and biofilm. Use of the formulations for prevention and treatment of other adverse oral conditions including inflammation and oxidative and/or free radical damage within the oral cavity are provided. Treatable conditions may relate to other conditions or diseases, including diabetes, AIDS and cancer. Oral formulations containing a biocompatible chelating agent, and a permeation enhancer such as methylsulfonylmethane (MSM) are disclosed. Components of the formulations are multifunctional and Generally Regarded As Safe.Type: ApplicationFiled: May 3, 2013Publication date: May 14, 2015Inventors: Rajiv Bhushan, Jerry Gin, Amit Goswamy
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Publication number: 20150125503Abstract: The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics wherein the amino acid at position (1) is changed to Ile or Gly, the amino acid at position (4) is changed to an Ala, the amino acid at position (4) is removed, the amino acid at position (5) is changed to an Ala, or wherein, as in the case of MU1140, the amino acid at position (13) is Arg, the Arg at position (13) is substituted with Asp, or combinations of two or more these changes or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: February 22, 2013Publication date: May 7, 2015Inventors: Jeffrey D. Hillman, James Leif Smith, Shawanda R. Wilson-Stanford
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Publication number: 20150079009Abstract: The present invention relates to the use of a combination of glycine, proline, and optionally a natural or synthetic film-forming polymer, and/or lysine and/or leucine, to prepare a composition for the treatment of mucositis induced by radiation or chemotherapy.Type: ApplicationFiled: November 25, 2014Publication date: March 19, 2015Inventors: Franco Conti, Francesco Saverio Dioguardi
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Patent number: 8980232Abstract: A dental care product comprises an orally acceptable carrier or excipient, and a bacterial resistance copolymer, which comprises a zwitterionic block and a charged anchoring block, wherein the anchoring block binds to tooth surfaces by electrostatic attraction, and the zwitterionic block extends outwardly to reduce the attachment of bacteria to tooth surfaces.Type: GrantFiled: November 23, 2010Date of Patent: March 17, 2015Assignee: Chung Yuan Christian UniversityInventors: Yung Chang, Yu-Ju Shih, Bor-Shiunn Lee, Ruoh-Chyu Ruaan, Da-Ming Wang, Juin-Yih Lai
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Patent number: 8980229Abstract: The invention encompasses compositions and methods for treating and modifying surfaces of teeth, which compositions include calcium and magnesium containing silicates or silica, cationic polymer modified silica or combinations thereof. The composition when applied to the teeth or a tooth surface deposit on such surfaces to repair acid damaged enamel and prevent further erosion of a tooth surface.Type: GrantFiled: April 1, 2009Date of Patent: March 17, 2015Assignee: Colgate-Palmolive CompanyInventors: Shira Pilch, James Gerard Masters
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Patent number: 8980233Abstract: Disclosed is a dentifrice composition comprising an orally acceptable vehicle, an abrasive particulate and a surfactant system comprising an anionic surfactant comprising a C8-C16 fatty acid glutamate salt and a nonionic surfactant comprising a C8-C16 alkyl glucoside.Type: GrantFiled: October 31, 2013Date of Patent: March 17, 2015Assignee: Tom's of Maine, Inc.Inventors: Tammy Swett, Julie Venell, Chantal Bergeron, Mark Dobrovolny, Stefan Gafner
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Patent number: 8974805Abstract: The present invention relates to a dental cleanser composition for improving adhesion to teeth, and more particularly to, a dental cleanser composition which functions to remove not only a smear layer from the dentin surface of an exposed tooth root, but also oral bacteria, and thus is effective in improving adhesion to teeth in periodontal surgery. The present invention provides a dental cleanser composition containing sodium ethylene diaminotetraacetate and octyl phenol ethoxylate which is a surfactant. Sodium ethylene diaminotetraacetate in the composition functions to remove a smear layer on the tooth root surface and has antibacterial activity, and octyl phenol ethoxylate in the composition functions to lipopolysaccharide. Thus, the composition improves adhesion to teeth in periodontal surgery.Type: GrantFiled: February 28, 2011Date of Patent: March 10, 2015Assignee: Nano Intelligent Biomedical Engineering CorporationInventors: Chong-Pyoung Chung, Yoon-Jeong Park, Jue-Yeon Lee
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Patent number: 8968710Abstract: A topical anesthetic is provided containing about 3 wt % to 10 wt % tetracaine in a vehicle suitable for administration to the skin or mucosa. The vehicle for transporting the tetracaine includes a water soluble mucoadhesive or a combination of mucoadhesives such as a high molecular weight poly(ethylene oxide) homopolymer and a cellulose polymer. The vehicle also includes propylene glycol. The tetracaine is ground into a powder and is suspended in a plasticized hydrocarbon gel which completes the vehicle.Type: GrantFiled: January 6, 2014Date of Patent: March 3, 2015Inventors: Alan J. Wickenhauser, Stephen E. Peipert
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Patent number: 8968709Abstract: Dental compositions are provided comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof: wherein n is an integer from about 2 to about 5.Type: GrantFiled: July 10, 2008Date of Patent: March 3, 2015Assignee: 3M Innovative Properties CompanyInventors: Jie Yang, Bhaskar V. Velamakanni, Sumita B Mitra, Alphonsus V. Pocius, John J. Stofko, Jr., Jeremy M. Yarwood
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Patent number: 8955528Abstract: The instant application is an all-natural denture cream designed to remove stains, clean, disinfect, and shine the denture with minimal effort within seconds There is also an added double headed brush that can be used with the cream, with a curved easy grip feature that will allow for easy cleaning experience. The brush is designed to reach those hard to access spots of the denture that could not be otherwise accessed by the fingers alone.Type: GrantFiled: June 30, 2014Date of Patent: February 17, 2015Inventors: Guillermo Escobar, Jorge Leonardo Valderrama
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Publication number: 20150044147Abstract: The composition for management of periodontal diseases includes a gel matrix having a polymer system and a plurality of microspheres dispersed in the polymer system. The polymer system contains about one-half a dose of medicament, while the microspheres contain the remainder. Upon administration of the composition into the periodontal cavity, the medicament in the polymer system provides an initial therapeutic benefit, while the remainder of the medication is released over time via degradation of the microspheres. This biphasic pattern of medicament delivery provides increased efficacy of the medicament through sustained delivery of the same.Type: ApplicationFiled: October 22, 2014Publication date: February 12, 2015Inventors: NOHA MOHAMED ZAKI RAYAD, IBRAHIM MAGHRABI, MOHAMED MOSTAFA HAFEZ MAHMOUD
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Patent number: 8951509Abstract: The invention relates to novel optionally quaternized or protonated condensation polymers having at least one heterocyclic end-group connected to the polymer backbone through a unit derived from an alkylamide, the connection comprising an optionally substituted ethylene group and to the use thereof in body care products and household products.Type: GrantFiled: February 23, 2007Date of Patent: February 10, 2015Assignee: DSM IP Assets B.V.Inventors: Raphael Beumer, Franciscus Derks, Christine Mendrok
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Publication number: 20150004105Abstract: Oral care compositions comprising one or more active agents and hydroxypropyl cellulose, and that are liquid at or below room temperature and which form a two-phase cloudy system at body temperature. In certain embodiments the active agent is a mineralizing agent, an anti-caries agent, an anti-inflammatory agent, an antibacterial agent, an antifungal agent, an anti-malodour agent or a mixture thereof.Type: ApplicationFiled: December 11, 2012Publication date: January 1, 2015Inventors: Mark Ieuan Edwards, Simon King, Nisha Patel
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Publication number: 20140369941Abstract: Described herein are aqueous oral compositions comprising cationic steroidal compound and a quaternary ammonium compound; and methods for making and using the same.Type: ApplicationFiled: December 21, 2011Publication date: December 18, 2014Applicant: BRIGHAM YOUNG UNIVERSITYInventors: Joe Vazquez, Dandan Chen, Harsh M. Trivedi, Ammanuel Mehreteab, Laurence Du-Thumm, Gregory Szewczyk, Zhigang Hao
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Publication number: 20140348762Abstract: Described herein are methods for identifying a mammal having a heightened susceptibility to enamel erosion, together with kits therefor and uses and methods related thereto.Type: ApplicationFiled: December 20, 2011Publication date: November 27, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Lynette Zaidel, Steven Miller, Guy Carpenter, Gordon Proctor, David Bartlett, Rebecca Moazzez
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Publication number: 20140348760Abstract: Described herein are oral care compositions comprising (i) a magnesium alkali metal silicate complex clay, and (ii) an orally acceptable anionic polymer, in a dentifrice base, which compositions are useful for alleviating dental sensitivity. Also provided for, are methods of making and using the compositions described herein.Type: ApplicationFiled: December 21, 2011Publication date: November 27, 2014Applicant: Colgate-Palmolive CompanyInventors: Suman Chopra, Lin Fei, Rahul Patel
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Publication number: 20140341820Abstract: Described herein are compositions comprising zirconium amino acid complexes suspended in a hydrophobic carrier; and methods of making and using the same.Type: ApplicationFiled: December 21, 2011Publication date: November 20, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Venda Porter Maloney, Suman Chopra, Sergio Leite, Long Pan, Rahul Patel
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Patent number: 8889106Abstract: A non-alcohol mouthwash composition without chemical antibacterial medicament is disclosed. The non-alcohol mouthwash composition includes from 0.03% to 1.5% of ?-polyglutamic acid (?-PGA) and from 0.5% to 4% of surfactant, all percentages based on the total weight of the mouthwash composition. The non-alcohol mouthwash composition preferably includes from 0.4% to 1.5% by weight, or more preferably from 0.8% to 1.3% by weight, of ?-PGA. Containing no chemical antibacterial medicament, the non-alcohol mouthwash composition can effectively inhibit bacterial growth in the oral cavity without irritating the oral mucosa.Type: GrantFiled: June 28, 2013Date of Patent: November 18, 2014Inventors: Feng-Huei Lin, Chun-Pin Lin, Hsuan-Yu Chen, Tzu-Piao Tang, Hsu-Wei Fang, Chung-King Hsu, Chia-Ming Chang
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Patent number: 8883179Abstract: Described herein are compositions comprising a MMP-13 inhibitor, and methods of using the same.Type: GrantFiled: December 21, 2010Date of Patent: November 11, 2014Assignee: Colgate-Palmolive CompanyInventors: Wei Wang, Virginia Barnes, Harsh M. Trivedi, Tao Xu
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Publication number: 20140322307Abstract: The present invention refers to a peptide of general formula (I) R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2, cosmetic compositions which comprises said peptide, method of preparation of said peptides and its use in the treatment and/or prevention of itching, inflammation, pain, diseases and/or disorders of the respiratory airways.Type: ApplicationFiled: October 31, 2012Publication date: October 30, 2014Inventors: Antonio Vicente Ferrer Montiel, José María García Antón, Raquel Delgado González
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Patent number: 8871183Abstract: A composition for improving oral health and methods of using and forming the composition are disclosed. The composition includes one or more active ingredients and a carrier. The composition is configured to maintain the active ingredient(s) with a surface of an oral cavity for an extended period of time to promote oral health and hygiene.Type: GrantFiled: May 15, 2007Date of Patent: October 28, 2014Assignee: Zicare, LLCInventors: Tim Clarot, Regina Miskewitz
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Publication number: 20140314819Abstract: The present disclosure provides methods and compositions for treating or reducing a dental condition in an animal, particularly in canine and feline companion animals. Compositions useful in the disclosed methods comprise an effective amount of lactic acid. The disclosed compositions may also contain oral health promoting effective amounts of at least one antioxidant. Dental conditions treated or reduced according to the disclosed methods include dental plaque, calculus, tooth staining, halitosis, stomatitis, gingivitis, periodontitis, and combinations thereof.Type: ApplicationFiled: August 30, 2012Publication date: October 23, 2014Applicant: HILL'S PET NUTRITION, INC.Inventors: Dale S. Scherl, Dennis Jewell, Philip W. Toll, Kevin A. Hahn
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Publication number: 20140305461Abstract: Described herein are aqueous oral care compositions comprising (a) an effective amount of a basic amino acid in free or orally acceptable salt form; and (b) a polymer system comprising (i) a cellulosic polymer, (ii) a gum polymer, and (iii) a polyacrylate polymer or co-polymer; and methods of making and using the same.Type: ApplicationFiled: December 15, 2011Publication date: October 16, 2014Applicant: Colgate-Palmolive CompanyInventors: Paloma Pimenta, Davide Miksa, Shira Pilch, Aarti Rege, Richard Sullivan
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Publication number: 20140308217Abstract: Described herein are oral care compositions comprising (i) an orally acceptable gallium salt and (ii) a basic amino acid polymer, in amounts effective to disrupt biofilm; and methods of making and using the same.Type: ApplicationFiled: December 15, 2011Publication date: October 16, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Lyndsay Schaeffer-Korbylo, Christine Cuiule, Laurence Du-Thumm
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Publication number: 20140286881Abstract: This document provides methods and materials for providing teeth with a white appearance. For example, methods and materials for contacting teeth with one or more fluorescence emitting polypeptides (e.g., a blue fluorescent protein (BFP)) to provide the teeth with a whiter appearance are provided.Type: ApplicationFiled: June 11, 2014Publication date: September 25, 2014Applicant: SafeWhite LLCInventors: Scott Joseph Bridgeman, Richard Simon Brody, Thomas Joel Zupancic
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Publication number: 20140286880Abstract: The invention provides ethanol-free liquid oral care compositions comprising cetyl pyridinium chloride which do not have an unacceptably bitter taste, e.g. mouthwashes, toothpastes, throat sprays, and breath sprays that are substantially free of ethanol, e.g., comprising (i) an antimicrobially effective amount of cetyl pyridinium chloride (CPC), (ii) one or more flavoring oils which are substantially insoluble in water at room temperature, and (iii) water, wherein the ratio of the CPC to the one or more flavoring oils is from 1:1.5 to 1:2.5, as well as methods of making and using the same.Type: ApplicationFiled: November 9, 2011Publication date: September 25, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Robert Vogt, Karsten Kohrs, Evangelia S. Arvanitidou, Fernando Perna
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Publication number: 20140271501Abstract: The present disclosure relates to methods and compositions administered to the lymphatic tissue of an animal to prevent or reduce the incidence of disease or disease symptoms caused by one or more disease causing entities. Tonsillar compositions can be administered to the lymphatic tissue in the oral/nasal region of the animal and can include avian antibodies from eggs of hens inoculated with one or more target disease causing entities. Treating the lymphatic tissue in the oral/nasal region with the compositions described herein can reduce or prevent the disease causing entities from adhering to the lymphatic tissue resulting in reduced infection rates. The present disclosure also relates to oral compositions that can be used to reduce or eliminate oral pathogens in animals.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Camas IncorporatedInventors: Bradley M. Mitteness, Connie Phillips
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Publication number: 20140271500Abstract: This document provides methods and materials for providing teeth with a white appearance. For example, methods and materials are provided for contacting teeth with one or more fluorescence emitting polypeptides (e.g., a blue fluorescent protein (BFP)) and adhesive molecules (e.g., mussel adhesive polypeptides) to provide the teeth with a whiter appearance.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: SafeWhite LLCInventors: Richard Simon Brody, Thomas Joel Zupancic, Nicole Hoefer, Uday B. Sandbhor
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Publication number: 20140242001Abstract: The invention provides novel dental film-forming compositions, comprising i. an acrylate/octylacrylamide copolymer, ii. one or more alkyl cellulose ethers, and iii. a solvent, and optionally further comprising whitening materials and/or active agents, together with method for using the same.Type: ApplicationFiled: November 7, 2011Publication date: August 28, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Shyamala Pillai, Guofeng Xu
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Publication number: 20140234233Abstract: Described are associative thickeners based on compounds which comprise at least one hydrophobically modified polyether dendron end group.Type: ApplicationFiled: April 28, 2014Publication date: August 21, 2014Applicant: BASF SEInventors: Holger Türk, Volker Wendel, Anna Cristadoro, Rabie Al-Hellani, Bernd Bruchmann
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Patent number: 8795638Abstract: This invention pertains to dental care compositions with antimicrobial benefits. In particular, the invention provides for compositions of oral tissue-adherent salts that release biocidal ions on a controlled release basis and thereby provide and maintain an essentially uniform concentration of biocidal ions above the MBC or MIC of the target bacteria at the site of application in the mouth for an extended period of time. The compositions are useful for treating or preventing oral diseases resulting from bacteria, fungal or yeast infections, such as caries, gingivitis, periodontal disease and candidiasis.Type: GrantFiled: October 6, 2011Date of Patent: August 5, 2014Assignee: Nevada Naturals Inc.Inventors: Anthony Errol Winston, Richard F. Stockel, Anthony Joseph Sawyer
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Publication number: 20140212459Abstract: The invention relates to 10H-benzo[g]pteridine-2,4-dione derivatives, to the production thereof, and to the use thereof.Type: ApplicationFiled: June 22, 2012Publication date: July 31, 2014Inventors: Tim Maisch, Andreas Späth
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Publication number: 20140186275Abstract: Agents and methods are provided for toothpaste for an electric toothbrush. The oral and dental care and cleaning agent includes at least one anionic surfactant and at least one amphoteric surfactant. A weight ratio of the at least one anionic surfactant to the at least one amphoteric surfactant(s) is ?6.Type: ApplicationFiled: March 6, 2014Publication date: July 3, 2014Applicant: HENKEL AG & CO. KGGAInventors: Christel Adomat, Nicole Duschek, Claudia Hundeiker
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Publication number: 20140186273Abstract: A composition for re-constructing enamel-coated substrates such as a tooth which includes an amelogenin, chitosan, and water. The composition may also include compounds providing calcium and phosphate ions. Methods using the composition are also provided.Type: ApplicationFiled: December 27, 2013Publication date: July 3, 2014Applicant: University of Southern CaliforniaInventors: Janet MORADIAN-OLDAK, Qichao RUAN
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Patent number: 8758729Abstract: The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present invention also relates to methods for preventing or treating periodontal disease and caries which include delivering a therapeutically effective amount of an oral composition containing a polyguanidine compound into an oral cavity.Type: GrantFiled: May 18, 2009Date of Patent: June 24, 2014Assignee: Colgate-Palmolive CompanyInventors: Andrew Nowak, Shira Pilch, Jim Masters
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Publication number: 20140170082Abstract: The present invention provides a novel method for improving the flavor of a food, drink, pharmaceutical product, oral care product, or the like. One aspect of the present invention is a method for improving the flavor of a food, drink, pharmaceutical product or oral care product, the method including the step of adding 0.1 to 10000 ppb of ?-aminobutyric acid and 0.01 to 10000 ppb of naringenin to the food, drink, pharmaceutical product, or oral care product.Type: ApplicationFiled: July 12, 2012Publication date: June 19, 2014Applicant: TAKASAGO INTERNATIONAL CORPORATIONInventors: Yoshikazu Toyohara, Tadahiro Hiramoto, Naoto Omotani
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Publication number: 20140161744Abstract: In a personal care daily practice, common human malodor in breath can be treated and eliminated or substantially reduced through the use of a treatment comestible, lozenge, chewing gum or scraper prepared by combining a hardenable natural or artificial sweetener or gum base with an amount of activated carbon effective in reducing such malodors.Type: ApplicationFiled: December 5, 2013Publication date: June 12, 2014Applicant: Vapor Shield Inc.Inventor: David M. PHILLIPS
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Publication number: 20140161745Abstract: The present invention relates to a kit of parts for detection and removal of carious dentin tissue comprising: (i) one or more compounds being a hydrazine derivative, and (ii) means for chemical treatment of carious dentin tissue. Further, the invention concerns a preparation containing an active, caries-dissolving two-component liquid in the form of a first active, caries-dissolving component and a second component which reduces the aggressiveness of the active component to mucous membranes, a viscosity increasing substance and one or more compounds being a hydrazine derivative. The hydrazine derivative labels carious dentin tissue selectively and substantially irreversibly in the presence of healthy dentin tissue, which is useful in the context of caries removal.Type: ApplicationFiled: June 15, 2012Publication date: June 12, 2014Applicant: RLS GLOBAL ABInventors: Ulrica Almhöjd, Åke Nilsson
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Publication number: 20140161743Abstract: Disclosed is a dentifrice composition comprising an orally acceptable vehicle, an abrasive particulate and a surfactant system comprising an anionic surfactant comprising a C8-C16 fatty acid glutamate salt and a nonionic surfactant comprising a C8-C16 alkyl glucoside.Type: ApplicationFiled: October 31, 2013Publication date: June 12, 2014Applicant: Tom's of Maine, Inc.Inventors: Tammy Swett, Julie Venell, Chantal Bergeron, Mark Dobrovolny, Stefan Gafner
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Publication number: 20140141389Abstract: A method of treating gum disease using a soft tissue diode laser which generates a beam of light having a wavelength in the visible portion of the electromagnetic spectrum (400 nm-700 nm) at a laser power of 0.5 to 1.2 watts, used with intermittent stops to control tissue temperature, to decontaminate the gum tissue and biostimulate the periodontium nonsurgically when used with a substrate, thus preventing the long junctional epithelium from migrating into the sulcus, preserving tissue height, and regenerating periodontium, the method comprising: placing the tip of the laser inside the sulcus; penetrating the entire sulcus by moving the laser light with intermittent stops to control tissue temperature vertically and horizontally throughout the sulcus; and placing a substrate in the sulcus prior to a blood clot forming, thus regenerating periodontium in the sulcus.Type: ApplicationFiled: April 16, 2013Publication date: May 22, 2014Inventor: Margaret V. Kalmeta
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Publication number: 20140134115Abstract: The present invention relates to oral compositions, comprising select phospholipid surfactants. Methods for using the compositions are also disclosed.Type: ApplicationFiled: November 13, 2012Publication date: May 15, 2014Applicant: McNeil-PPC, Inc.Inventors: Patricia L. Golas, Carolyn J. Mordas
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Publication number: 20140127144Abstract: A compound of formula (I) is used to modify the taste or flavour of a flavour composition or consumable product, wherein R1 is H, or a substituted, unsubstituted, branched or unbranched C1-C5 alkyl group and, NHR2 is a residue of an amino acid, is selected from Alanine (Ala), cysteine (Cys), Aspartic acid (Asp), phenylalanine (Phe), glutamic acid (Glu), histidine (His), isoleucine (Ile), lysine (Lys), leucine (Leu), methionine (Met), asparagines (Asn), glutamine (Gln), arginine (Arg), serine (Ser), theronine (Thr), valine (Val), tryptophan (Trp), tyrosine(Tyr) and Glycine (Gly), with the proviso that the compound is not N-acetyl glycine. Also disclosed are flavour compositions and consumable products containing such compounds.Type: ApplicationFiled: January 9, 2014Publication date: May 8, 2014Applicant: Givaudan S. A.Inventors: Xiaogen YANG, Elisabetta LUBIAN, Harry RENES, Alexander P. TONDEUR, Stephan HAIBER, Xinping LIU, Xun FU