Abstract: Dental hygiene compositions containing as antiplaque/antiseptic/deodorizing active ingredient highly pure alkali metal lauryl sulphate substantially free from non-lauryl alkyl salts.

Abstract: Dental hygiene compositions containing as antiplaque/antiseptic/deodorizing active ingredient highly pure alkali metal lauryl sulphate substantially free from non-lauryl alkyl salts.

Abstract: An invention providing a process for producing orally-usable products possessing low- or anti-cariogenic properties is disclosed. The process comprises preparing said products with, or adding thereto a saccharide having a substantial anti-cariogenicity. The saccharides preferred in the invention are isomaltosyl mono-, di-, tri-glucoses, and reduction products thereof; for example, panose, isomaltotriose, isomaltosyl maltose, isomaltotetraose, isomaltopentaose, and reduction products thereof, i.e., pannitol, isomaltotriitol, isomaltosyl maltitol, isomaltotetraitol, and isomaltopentaitol. Such saccharides can be used in the production of any products used orally, including foods and drinks in general, to impart thereto a substantial low- or anti-cariogenic property, as well as to sweeten them.

Abstract: A stable dextranase-containing oral composition having a good feeling upon use is disclosed which comprises a dextranase enzyme produced by the genus Chaetomium, one of fungi, and a stabilizing amount of an admixture comprising water-soluble salts of alkyl sulfates having 10, 12, 14, and 16 carbon atoms in the alkyl chain in the following proportion:______________________________________ C.sub.10 --alkyl sulfate salt 0-20%, C.sub.12 --alkyl sulfate salt 50-80%, C.sub.14 --alkyl sulfate salt 10-30%, and C.sub.16 --alkyl sulfate salt 0-15%, ______________________________________based on the weight of the admixture.

Abstract: 3-l-Menthoxypropane-1,2-diol having the formula: ##STR1##

Abstract: This invention is a cleansing agent specifically for wearers of partial and complete dentures, whose gums, hard and soft palates, tongue and all inner mouth surfaces require thorough cleaning when the partial or full dental appliances are removed from the mouth.

Abstract: A liquid hemostatic composition for local application to small hemorrhage in the dental field which comprises one or more astringents selected from the group consisting of aluminum chloride, tannic acid, ferric chloride, zinc chloride and potassium aluminum sulfate; one or more surfactants selected from the group consisting of cetyl pyridinium chloride, benzalkonium chloride, benzethonium chloride, chlorhexidine, chlorhexidine gluconate, lauryl sulfate, a polyoxyethylene sorbitan fatty acid ester, a polyoxyethylene fatty acid ester, a polyoxyethylene higher alcohol ether, a polyoxyethylene alkyl aryl ether, a polyoxyethylene lanolin derivative, a polyoxyethylene lanolin alcohol derivative, a polyoxyethylene castor oil derivative, a polyoxypropylene-polyoxyethylene alkyl ether and a polyoxyethylene alkylphenol-formaldehyde condensate; and a carrier or diluent selected from the group consisting of water and a mixture of water and one or more pharmaceutically acceptable water-soluble organic solvents.

Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated vinylaromatic homopolymers and copolymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and the periodic application thereof to teeth.

Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise condensation polymers of formaldehyde with naphthalene sulfonic acid as well as the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and the periodic application thereof of teeth.

Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated aromatic formaldehyde condensation polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and the periodic application thereof to teeth.

Abstract: Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated alkoxynaphthalenes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.

Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated poly(arylene ether sulfone) polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and the periodic application thereof to teeth.

Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain pharmaceutically acceptable salts of sulfonated alkylnaphthalenes. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.

Abstract: Compositions for preventing the attachment of dental plaque to the surfaces of the teeth comprise certain sulfonated poly(arylene ether sulfone) polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable nonabrasive gel vehicle comprising a selected polyoxypropylene/polyoxyethylene block copolymer as the principal gelling agent.

Abstract: A toothpaste of improved rheological properties wherein drying and plug formation is reduced or prevented. The toothpaste contains a vehicle in which there is present about 45-85% by weight of liquid phase containing up to about 35% by weight of sorbitol and at least about 25% by weight of water and a solid phase including about 0.5-10% by weight of gelling agent. Drying and plug formation is reduced by including in the liquid phase about 5-20% by weight of polyethylene glycol having an average molecular weight between about 900 and 1600.

Abstract: A dentifrice comprising an impure insoluble sodium metaphosphate polishing agent is disclosed, the dentifrice using a mixture of anionic phosphates esters as a surface active agent, to reduce or prevent a tendency to cause sloughing or desquamation.

Abstract: Carbalkoxymethyl derivatives of rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.

Abstract: L-1-hydroxymethyl alkaneamide derivatives of .alpha.-L-aspartic acid have been prepared and have been discovered to be non-nutritive sweeteners having favorable chemical and physiological properties for use in compositions ingested orally.

Abstract: N-(4-O-.alpha.-D-glucopyranosyl-.beta.-D-glucopyranosyl)-3,4-dihydroxycinna mamide, nonakis (H-sulfate) (nonaester), nona-alkali metal or alkaline earth metal-salts, useful as modulators of the complement system, the intermediates thereof and the process of making such salts and intermediates.

Abstract: Polymers useful in compositions and methods for preventing the attachment of dental plaque to the surface of the teeth of mammals comprise certain sulfonated polyamino acids and salts thereof in a pharmaceutically acceptable vehicle and the periodic application thereof to teeth.

Abstract: Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated bis(naphthoxy)alkanes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.

Abstract: Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated bis(alkylphenoxy)alkanes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.

Abstract: Dental cream having a smooth texture with little tendency to form grain containing calcium carbonate polishing agent and sodium lauryl sulphate surface active agent having a broad distribution of alkyl groups containing 10-18 carbon atoms and as additive which reduces grain and alkali metal pyrophosphate or an anionic phosphate mono- and di-ester mixture.

Abstract: Dental cream having a smooth texture with little tendency to form grain containing calcium carbonate polishing agent and sodium lauryl sulphate surface active agent having a broad distribution of alkyl groups containing 10-18 carbon atoms and as additive which reduces grain an alkali metal pyrophosphate or an anionic phosphate mono- and di-ester mixture.

Abstract: Oral compositions which contain as a sweetening agent 6-methyloxathiazinone dioxide or an alkali metal or alkaline earth salt thereof in an amount of from about 0.05% to about 0.80%.

Abstract: The present invention relates to an improved method for cleansing of human teeth to help reduce and control dental plaque as an aid in preventing dental caries and periodontal disease. In particular, it relates to a viscous composition of particular characteristics and a process for application thereof to accomplish these objectives.

Abstract: A clear gel dentifrice containing "narrow cut" alkali metal lauryl sulphate in which the C.sub.12 content is at least 90% by weight of the total alkyl content and a fluorine providing compound. The dentifrice contains a further anionic surface active agent which is a substantially saturated higher aliphatic acyl amide of a lower aliphatic amino carboxylic acid salt, a substantially saturated higher fatty aliphatic alcohol alkylene oxide sulphate or a mixture of mono- and di- phosphate esters.

Abstract: A dentrifice in paste or powder form which contains, in addition to the usual constituents, at least one physiologically compatible, natural or synthetic dye and at least one high-foam surfactant and in which the dye and surfactant contents are so co-ordinated that colored foam produced by the user on brushing takes 20 seconds or more to become white or only pale in color so that this serves as an indication of the correct period of brushing necessary.

Abstract: A toothpaste composition contains an alkali metal aluminum silicate zeolite as the polishing agent base. The composition is non-corrosive to aluminum containers, polishes well without excessive abrasion and is compatible with dental fluorine compounds. A particularly suitable polishing agent is Zeolite A having the empirical formula Na.sub.12 (AlO.sub.2).sub.12.(SiO.sub.2).sub.12.27H.sub.2 O.

Abstract: A dentifrice useful for remineralizing subsurface carious lesions of dental enamel which contains sources of calcium ions and phosphate ions as well as fluoride ions and further includes as agent to stabilize against precipitation of the calcium and phosphate ions, an antinucleating agent such as ethylenediamine tetramethylenephosphonic acid or water soluble salt thereof, the pH of the dentifrice being about 5-9, preferably close to physiological conditions, such as about 6.8-7.5.

Abstract: Dentifrice possessing superior cleaning and polishing characteristics containing as the essential ingredients at least one hard abrasive in an amount to provide a radioactive enamel abrasion to the dentifrice of above about 400, such as calcined alumina, zirconium silicate, and the like, and a non-toxic zinc compound in an amount to provide at least about 0.0065% by weight of zinc to the dentifrice.

Abstract: This invention discloses compositions effective in inhibiting or reducing plaque in the oral cavity. Chewing gums are a preferred vehicle for delivering the plaque inhibiting benefit of the present invention.

Abstract: An oral composition effective to promote oral hygiene containing as an anticalculus agent a water soluble oligomer of the formula ##STR1## wherein M is a water soluble orally acceptable cation;R.sub.1, r.sub.2, r.sub.3 and R.sub.4 are independently H, methyl or ethyl;Y is at least one hydrophilic member of the group consisting of --COOM.sub.1, --CONH.sub.2, and --CH.sub.2 OH:X is at least one hydrophobic member of the group consisting of --CN, --COOR, --COOR.sub.5 OR, --CONHR, --COONHR.sub.5 COR, and --OOCR;M.sub.1 is H or M;R is C.sub.1-8 alkyl;R.sub.5 is C.sub.1-4 alkylene;A is 0-7; andA+b is about 4-15.

Abstract: This invention discloses compositions effective in inhibiting or reducing plaque in the oral cavity. Chewing gums are a preferred vehicle for delivering the plaque inhibiting benefit of the present invention.

Abstract: A physiologically acceptable, germicide free antibacterial liquid mouthwash and methods for its use is disclosed. The mouthwash comprises water, ethanol, an essential oil flavor mixture and about 0.1 to about 0.6 percent of an alkyl sulfate anionic surfactant mixture of C.sub.12 and C.sub.14 sulfates wherein the ratio of C.sub.12 to C.sub.14 alkyl sulfates is in the range of about 75:1 to about 1:1. Additional ingredients which may be incorporated within specific ranges include nonionic emulsifiers, humectants, alkali metal halides, buffering salts, sweetening agents and colorants.

Abstract: A novel composition to prevent and control mouth odor, which is also effective in preventing calculus, plaque, caries and periodontal disease containing as the essential agent, a zinc-polymer combination formed by the reaction or interaction of a zinc compound with an anionic polymer containing carboxylic, sulfonic and/or phosphonic acid radicals.

Abstract: There is disclosed an oral product containing a new and improved surfactant system that is non-toxic, edible and surprising substantially tasteless.

Abstract: Novel N-tricyclic derivatives of azetidine are disclosed of the general formula ##STR1## where A is a C.sub.1 -C.sub.3 alkylene group, a C.sub.2 -C.sub.3 alkenylene group or a cyclopropylene group, the remaining substituents being defined in the specification. Such compounds are useful for their anti-depressant, anti-convulsant and anxiolytic activities. The compound 1-[5-(10, 11-dihydro-5H-dibenzo [a,d]cyclopheptenyl)]-3-methyl-amino-azetidine is illustrative.

Abstract: Oral compositions containing an anticalculus agent selected from the group consisting of compounds having the following structural formulas: ##STR1## wherein X, X', Y, and Y' are selected from the group consisting of H, OH, SO.sub.3 Na, and CH.sub.2 N(CH.sub.2 COOH).sub.2 and additionally wherein at least two of the substituents X, X', Y, and Y' must be hydroxyls, and at least one of the further of said substituents must be OH, SO.sub.3 Na, or CH.sub.2 N (CH.sub.2 COOH).sub.2. The preferred anthraquinoid derivatives are Alizarin red S monohydrate, Alizarin complexone dihydrate, purpurin, and purpurin sulfonate.

Abstract: Compositions are disclosed having a physiological cooling action on the skin. The compositions contain as the active ingredient certain acyclic secondary and tertiary sulphoxides and sulphones.

Abstract: The addition of organo germanium compounds having the formulaR.sub.3 GeX or (R.sub.3 Ge).sub.2 Ywherein R is an aliphatic or cycloaliphatic hydrocarbon group and X is an anion, such as carboxylate, sulphonate, halogen or hydroxyl, and Y is oxygen, sulphur, or sulphate, to conventional agents used in oral hygiene will significantly reduce the formation of plaque on teeth and thus reduce the incidence of caries. The preferred germanium compounds are the tri-n-butyl and tri-n-pentyl. The fluoride ion is the preferred anion because of its known anti-caries properties.

Abstract: Compositions, particularly edible compositions, oral compositions and flavor compositions, containing a compound imparting a cooling sensation, said compound being a hydroxymethyl or hydroxyethyl derivative of para-menthane, for example 2-hydroxymethylmenthol.

Abstract: A liquid or pasty putrefaction resistant thixotropic gel dentifrice that is stable against phase separation of solid abrasive dentifrice particle ingredients which consists of 0.3 to 2% by weight of a polysaccharide having a number average molecular weight of not less than 100,000 and the molecule of said polysaccharide containing D-glucose, D-mannose, D-galactose and D-glucuronic acid in the molar ratio of about 3:3:1:2.

Abstract: An effervescent dentifrice in chewable tablet form particularly effective in controlling Bacillus Acidophilios comprising a compressed homogenous mixture of an acid neutralizer, a cariespreventative, an acid, a wetting agent, and flavoring and sweetening agents. Upon crushing the dentifrice tablet in the mouth, a pleasant-tasting, effective microbicide is released.

Abstract: An essentially non-aqueous oral hygiene product is disclosed comprising an alcohol base, a combination of viscosity adjusters, e.g., polyvinylpyrrolidone and glycerin; a detergent such as sodium lauryl sulfate; a sweetening agent such as saccharin, and a flavor additive. The combination of viscosity adjusters imparts a suitable viscosity and body to the product to enable it to adhere to a toothbrush and be readily dispersible in water to be used as a mouthwash.

Abstract: A mouthwash solution and method for treating both the lower and upper throat. The aqueous solution contains dioctyl sodium sulfosuccinate as the active ingredient. The treatment of the lower throat involves holding a small amount of the solution in the mouth for a short period of time. The treatment for the upper throat area is to hold a small amount of the solution in the mouth, lie down with the head back, swallow several times, and hold the head in position for a short period of time.

Abstract: There is disclosed a substantially anhydrous dentifrice which contains a dipeptide sweetener in combination with an acid anhydride. There is also disclosed a method of making the same.

Abstract: A liquid or pasty dentifrice comprising, uniformly incorporated therein, a polysaccharide as a thickening and suspending agent, said polysaccharide having a number average molecular weight (Mn) of not less than 100,000 and the molecule of said polysaccharide containing D-glucose, D-mannose, D-galactose and succinic acid in the approximate molar ratio of 1 : 0.03 : 0.1 : 0.2. The polysaccharide is obtained by cultivating Alcaligenes faecalis var. myxogenes in a culture medium containing at least one member selected from the group consisting of lactic acid, pyruvic acid, succinic acid, fumaric acid, malic acid and esters thereof and saccharide.