Ferrous Patents (Class 424/648)
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Publication number: 20040029853Abstract: Compositions in solid form, such as powders, comprising a mixture of a ferrous salt and a hydroxypyrone may be used to increase the level of iron in a patient's bloodstream or to treat and/or prevent gastrointestinal infection.Type: ApplicationFiled: July 28, 2003Publication date: February 12, 2004Inventor: Michael Arthur Stockham
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Patent number: 6689392Abstract: A composition for controlling growth of pathological organisms on a plant, said composition comprises an effective amount of one or more of metal ion(s); one or more of chelating agent(s); and phosphorous acid, and/or salt or hydrate thereof, said composition is in an agriculturally compatible carrier or vehicle.Type: GrantFiled: January 29, 2002Date of Patent: February 10, 2004Assignee: Agricare Ltd.Inventor: Ran Lifshitz
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Publication number: 20040013730Abstract: The present invention relates to a non-hormonal, biocompatible, and biodegradable intravaginal device for the delivery of spermiostatic, spermicidal and anti-infectious agents. The present invention also relates to methods of contraception using such a device, as well as the prevention and treatment of sexually transmitted diseases and vaginal infections through the application of the device.Type: ApplicationFiled: July 31, 2003Publication date: January 22, 2004Inventors: Brij B. Saxena, Mukul Singh, Sidney Lerner
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Patent number: 6680073Abstract: This invention relates to a composition and method for the treatment of white line disease, including ailments such as Onychomycosis, sporotichosis, hoof rot, jungle rot, pseudallecheria boydii, scopulariopsis or athletes foot. The composition of the present invention is useful for the treatment of fungal infections such as Onychomycosis in warm blooded animals such as humans and horses. The method of the present invention is directed to the application of a therapeutic amount of the present composition.Type: GrantFiled: April 10, 2000Date of Patent: January 20, 2004Inventor: Bryon J. Tarbet
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Patent number: 6669966Abstract: Skin-growth-enhancing compounds and compositions including a therapeutically effective amount of at least one electron active compound, or a pharmaceutically acceptable derivative thereof, that has at least two polyvalent cations, at least one of which has a first valence state and at least one of which has a second, different valence state. Preferred compounds include Bi(III,V) oxide, Co(II,III) oxide, Cu(I,III) oxide, Fe(II,III) oxide, Mn(II,III) oxide, and Pr(III,IV) oxide, and Ag(I,III) oxide, or a combination thereof. These compounds may be in a crystalline state having metallic cations of two different valences, or electronic states, in the inorganic crystal. Also included are articles containing such compositions, such as wound dressings, and methods for facilitating or enhancing skin growth using these compounds, compositions, and articles, such as for the treatment or management of burns or skin grafts.Type: GrantFiled: October 20, 2000Date of Patent: December 30, 2003Assignee: Marantech Holding LLCInventor: Marvin S. Antelman
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Patent number: 6663852Abstract: The present invention relates to a new makeup kit comprising a first, goniochromatic pigment composition which is intended to form a base layer and a second, conventional pigment composition having one of the colors of the first pigment, the second composition being intended to form a surface layer comprising decorative motifs. Depending on the viewing angle, therefore, it is possible to see the said motifs appear or disappear. This kit is intended in particular for making up the nails, lips, cheeks or eyelids, or else the body. The invention also relates to a method of making up the human face, lips or body.Type: GrantFiled: August 15, 2002Date of Patent: December 16, 2003Assignee: L'OrealInventor: Jean-Christophe Simon
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Patent number: 6645531Abstract: The present invention is directed to pharmaceutical compositions that include a therapeutically effective amount of at least one electron active compound, or a pharmaceutically acceptable derivative thereof, that has at least two polyvalent cations, at least one of which has a first valence state and at least one of which has a second, different valence state. Preferred compounds include Bi(III,V) oxide, Co(II,III) oxide, Cu(I,III) oxide, Fe(II,III) oxide, Mn(II,III) oxide, and Pr(III,IV) oxide, and optionally Ag(I,III) oxide. These compounds may be in a crystalline state having metallic cations of two different valences, or electronic states, in the inorganic crystal. In addition, the invention relates to methods for prevention, management, or treatment of a condition using these compounds or pharmaceutical compositions including the same.Type: GrantFiled: October 20, 2000Date of Patent: November 11, 2003Assignee: Marantech Holding LLCInventor: Marvin S. Antelman
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Publication number: 20030206969Abstract: Multivitamin/Multimineral supplements are provided for supplementing iron and desirable nutrients in the diet of mammals. The supplements include an iron-amino acid chelate, a form of iron more bioavailable than traditional iron salts. The supplements may further include a pharmaceutically accepted salt form of iron as well as other nutritional vitamins and minerals. The supplements are useful for providing iron for pregnant and lactating females as well as for persons suffering from anemia.Type: ApplicationFiled: February 27, 2003Publication date: November 6, 2003Applicant: Integrity Pharmaceutical CorporationInventors: Prasad Nidamarty, William R. Hurd, Roland J. Bydlon, William C. Williams, Michael Dempsey, Amy Erbskorn
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Publication number: 20030170315Abstract: The object of the present invention is to stabilize bioactivation of iron salt. Said object is attained by adding a magnesium salt to said iron salt. Said iron salt stabilized by said magnesium salt is useful as medicine to treat incurable diseases such as diabetes and growth promoting agent of animals and plants.Type: ApplicationFiled: December 4, 2002Publication date: September 11, 2003Inventor: Shinji Makino
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Patent number: 6579541Abstract: The invention relates to a method and composition for destroying or inhibiting proliferation of microbes using oxidative fluorinator compounds. Fluoride salts that do not dissociate completely in aqueous solutions, such as tri- or tetravalent transition metal fluorides, inert gas fluorides, or tri- or tetravalent rare earth fluorides, are effective antimicrobial agents even at levels up to about 20 ppm, when used alone or in conjunction with a strong oxidizer.Type: GrantFiled: March 16, 2001Date of Patent: June 17, 2003Assignee: Marantech Holding, LLCInventor: Marvin S. Antelman
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Patent number: 6576594Abstract: A method of controlling algae in a municipal water plant including the step of adding an algicide-flocculant solution including 25-50 wt % acidic flocculent, 0-10 wt % polymer flocculant aid, an algicide consisting essentially of copper having a concentration of 0.025-1.275 wt % in the form of a water soluble copper salt, balance water. The algicide-flocculant solution may be added to the water via a clarifier of the water plant, a basin of the water plant, or a mixing chamber. The mixing chamber may be located within the clarifier, adjacent to the basin, or upstream of the clarifier and/or the basin.Type: GrantFiled: June 18, 2001Date of Patent: June 10, 2003Assignee: Bay Chemical and Supply CompanyInventors: Thomas J. Nier, Tosby L. Linn
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Patent number: 6569353Abstract: The present invention provides a universal decontamination formulation and method for detoxifying chemical warfare agents (CWA's) and biological warfare agents (BWA's) without producing any toxic by-products, as well as, decontaminating surfaces that have come into contact with these agents. The formulation includes a sorbent material or gel, a peroxide source, a peroxide activator, and a compound containing a mixture of KHSO5, KHSO4 and K2SO4. The formulation is self-decontaminating and once dried can easily be wiped from the surface being decontaminated. A method for decontaminating a surface exposed to chemical or biological agents is also disclosed.Type: GrantFiled: June 11, 1998Date of Patent: May 27, 2003Assignee: Lynntech, Inc.Inventors: Anthony Giletto, William White, Alan J. Cisar, G. Duncan Hitchens, James Fyffe
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Patent number: 6565891Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among children.Type: GrantFiled: August 23, 2002Date of Patent: May 20, 2003Assignee: Tsar Health Private Ltd.Inventor: Ranjit Kumar Chandra
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Patent number: 6562378Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among adolescents.Type: GrantFiled: August 16, 2002Date of Patent: May 13, 2003Assignee: TSAR Health Private Ltd.Inventor: Renjit Kumar Chandra
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Patent number: 6541038Abstract: A method for treating wood, characterized by impregnating wood with a metal-containing treating agent containing lignin and/or lignin derivatives and a metal, a metal compound, and/or a metal ion and oxidizing and/or macromolecularizing of the lignin and/or lignin derivatives in the wood to fix the metal component in the wood, and wood and woody materials obtained by the treating method. According to the method of the present invention, while effectively utilizing lignins, lignosulfonic acids, or lignosulfonic acid salts, leaching of the metal component can be suppressed to a low level to thereby retain the effects due to the incorporation of the metal components for a prolonged period.Type: GrantFiled: May 25, 2000Date of Patent: April 1, 2003Assignee: SDS Biotech K.K.Inventors: Keijitsu Tanaka, Hirobumi Aoki, Takashi Echigo
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Patent number: 6521265Abstract: A method of arresting the flow of blood and other protein containing body fluids flowing from an open wound and for promoting wound healing. In the method, a substantially anhydrous compound of a salt ferrate is provided for a unique use which, when hydrated after mixing with a victim's own blood or other aqueous media, produces Fe+++ thereby promoting clotting when applied in a paste form to the wound for a time sufficient to arrest substantial further blood and other body fluid flow from the wound. The compound is formed of a ferrate (VI) salt taken from the group consisting of H, Li, Na, K, Rb, Cs and Fr. However, to decrease or eliminate stinging sensation, the compound may be formed having a ferrate (VI) salt taken from the group consisting of Be, Mg, Ca, Sr, Ba, Ra, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Ge, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, In, Sn, Hf, Ta, W, Re, Os, Ir, Pt, Au, Hg, TI, Pb, Bi, Al, As, NH4 and N(C4H9)4.Type: GrantFiled: June 13, 2000Date of Patent: February 18, 2003Assignee: Biolife, L.L.C.Inventor: James A. Patterson
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Patent number: 6517849Abstract: This application relates to antiviral tissue paper comprising pyrrolidone carboxylic acid as an antiviral agent. When added to tissue paper pyrrolidone carboxylic acid has the ability to kill certain strains of viruses which come into contact with the tissue. In addition to its antiviral efficacy, pyrrolidone carboxylic acid tends to be mild to the skin thus mitigating the potential for skin irritation. Furthermore, upon transfer to the skin, pyrrolidone carboxylic acid assists in retention of the natural moisture of the skin while continuing to kill deleterious viruses.Type: GrantFiled: September 12, 2000Date of Patent: February 11, 2003Assignee: The Procter & Gamble CompanyInventors: Geoffrey Eugene Seger, Kimberly Ann Biedermann, Kamilah Apewaiye Gbadamosi, Stephen Robert Kelly, Paul Thomas Weisman
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Publication number: 20020168321Abstract: The invention relates to injectable compositions for increasing the image contrast between specific organ areas in the magnetic resonance imaging (MRI) of human and animal patients. This enables better differentiation of neighboring tissue portions. Methods of the preparation of such compositions and their use in the MRI of living subjects are also disclosed.Type: ApplicationFiled: August 10, 1999Publication date: November 14, 2002Inventors: HERVE TOURNIER, ROLAND HYACINTHE
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Patent number: 6465511Abstract: The use of transition metal complexes in the treatment of septic shock, in particular the hypotension associated therewith and pharmaceutical formulation comprising such complexes are disclosed. The use of such transition metal complexes in the treatment of other conditions caused by pathological NO production are also disclosed.Type: GrantFiled: August 27, 1997Date of Patent: October 15, 2002Assignee: Molichem Medicines, Inc.Inventors: Wieslaw Mieczyslaw Kazmierski, Luis Molina
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Publication number: 20020141964Abstract: A hemostatic agent for arresting the flow of blood and other protein containing body fluids flowing from an open wound and for promoting wound healing. One embodiment is directed to a substantially anhydrous admixture of an oxyacid salt and a hydrophilic proton donor which will hydrate in the presence of blood and body fluid to produce cations to promote blood clotting. The preferred oxyacid salts are alkali and alkaline earth salts of transition metals and halogen oxyacids with oxidizing capabilities sufficient to accelerate blood clotting. Another embodiment of the invention includes the compound containing an oxysalt plus a hydrophilic polymer such as carboxy methylcellulose, polyvinyl, alcohol, an alginate, and all soluble gums. Still another embodiment of the invention includes the compound formed of an oxyacid salt in combination with a hydrophilic proton donor and a solid desiccant which further accelerates blood coagulation reaction rates.Type: ApplicationFiled: January 19, 2001Publication date: October 3, 2002Inventors: James A. Patterson, John A. Thompson, Talmadge Kelly Keene
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Patent number: 6451294Abstract: The present invention relates to a new makeup kit comprising a first, goniochromatic pigment composition which is intended to form a base layer and a second, conventional pigment composition having one of the colors of the first pigment, the second composition being intended to form a surface layer comprising decorative motifs. Depending on the viewing angle, therefore, it is possible to see the said motifs appear or disappear. This kit is intended in particular for making up the nails, lips, cheeks or eyelids, or else the body. The invention also relates to a method of making up the human face, lips or body.Type: GrantFiled: April 12, 1999Date of Patent: September 17, 2002Assignee: L'OrealInventor: Jean-Christophe Simon
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Patent number: 6447794Abstract: A stomach-action molluscicide including a metal complexone as an active ingredient The term “complexone” as used herein refers to an organic ligand containing at least one iminodiacetic group —N(CH2CO2H2)2 or two aminoacetic groups —NHCH2CO2H which form stable complexes with most cations. Preferably, the complexone is a derivative of ethylenediaminetetraacetic acid.Type: GrantFiled: July 9, 2001Date of Patent: September 10, 2002Inventor: Colin Leslie Young
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Patent number: 6444218Abstract: The present invention provides an improved soft chewable multivitamin tablet in which vitamin C is separated from calcium pantothenate and/or minerals such as iron, copper, zinc and mixtures thereof in a core or multilaminate form and a process for preparing the same. The soft chewable multivitamin tablet of the present invention maintains its stability over a long-storage time in terms of the content and potency of vitamins while overcoming the problems of incompatibility, bad mouthfeel and palatability.Type: GrantFiled: June 8, 2001Date of Patent: September 3, 2002Assignee: Sam-A-Pharmaceuticals Co. Ltd.Inventors: Yoon Dong Han, Jong Bum Park
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Patent number: 6440450Abstract: The present invention provides an improved soft chewable multivitamin tablet in which vitamin C is separated from calcium pantothenate and/or minerals such as iron, copper, zinc and mixtures thereof in a core or multilaminate form and a process for preparing the same. The soft chewable multivitamin tablet of the present invention maintains its stability over a long-storage time in terms of the content and potency of vitamins while overcoming the problems of incompatibility, bad mouthfeel and palatability.Type: GrantFiled: May 19, 1999Date of Patent: August 27, 2002Assignee: Sam-Pharmaceutical Co., Ltd.Inventors: Yoon Dong Han, Jong Bum Park
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Patent number: 6423351Abstract: The invention provides methods for inhibiting oxidative degradation of pharmaceutical formulations comprising at least one oxidation-susceptible active drug ingredient which methods comprise adding an oxidation-inhibiting amount of a ferrous ion source, preferably in the form of a pharmaceuticalexcipient, to the formulation. The invention further provides pharmaceutical formulations comprising at least one oxidation-susceptible active drug ingredient and an oxidation-inhibiting amount of a ferrous iron source, preferably in the form of a pharmaceuticalexcipient. The invention still further provides for the use of a ferrous ion source as an anti-oxidant in pharmaceutical formulations.Type: GrantFiled: March 9, 2001Date of Patent: July 23, 2002Assignee: Pfizer Inc.Inventor: Hai Wang
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Patent number: 6423350Abstract: An inorganic antimicrobial composition has the formula AB2O4, wherein A and B are low temperature far infrared irradiating metals, A is Mg, Zn, Mn, Ni, Co, or Fe(II), B is Al, Cr(III), Mn(III) or Fe(III), and O is oxygen. An antimicrobial article is made by coating said composition on a porous honeycomb-shaped substrate. An organic antimicrobial article is made from a quaternary ammonium salt coated on a porous honeycomb-shaped substrate. Processes of making the antimicrobial articles are provided.Type: GrantFiled: February 7, 2001Date of Patent: July 23, 2002Assignee: Parker Holding Services Corp.Inventors: Yen-Kuen Shiau, Chung-Hsun Wu
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Patent number: 6420312Abstract: An algicide-flocculant solution for use in treating raw water in a municipal water plant to control algae, the algicide-flocculant solution including 25-50 wt % of an acidic flocculant, 0-10 wt % of a polymer flocculant aid, an algicide of essentially copper having a concentration of 0.025-1.25 wt % in the form of a water soluble capper salt, and balance water. Uniform mixing of the flocculant into the raw water simultaneously uniformly mixes the algicide of the algicide-flocculant solution into the raw water. The acidic flocculant is preferably aluminium sulfate, iron sulfate, iron chloride or mixtures thereof. The water soluble copper salt is preferably copper sulfate, copper chloride, copper nitrate, copper acetate or mixtures thereof. Moreover, the flocculant aid is a high molecular weight quaternary amine such as diallyldimethylammonium chloride.Type: GrantFiled: June 11, 2001Date of Patent: July 16, 2002Assignee: Bay Chemical and Supply CompanyInventors: Thomas J. Nier, Tosby L. Linn
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Patent number: 6413551Abstract: A termiticide which comprises at least one compound which in the presence of a termite produces a termiticidally effective amount of hydrogen sulfide.Type: GrantFiled: January 26, 2001Date of Patent: July 2, 2002Inventor: David William Holloway
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Patent number: 6406532Abstract: A titanium dioxide powder/iron oxide mixed oxide which is prepared from FeCl3 and TiCl4 using a pyrogenic, especially a flame hydrolytic method. A further possibility is to coat pyrogenically, especially flame hydrolytically prepared titanium dioxide with iron oxide in aqueous dispersion. Both of these titanium dioxide powders which contain iron oxide may be used as a UV absorber in sunscreens.Type: GrantFiled: September 14, 1995Date of Patent: June 18, 2002Assignee: Degussa AktiengesellschaftInventors: Werner Hartmann, Dieter Kerner
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Publication number: 20020064567Abstract: Antiviral and antifungal compositions comprise a ferrous salt and a plant extract of pomegranate rind, Viburnum plicatum leaves or flowers, tea leaves or maple leaves in aqueous solution.Type: ApplicationFiled: October 11, 2001Publication date: May 30, 2002Inventors: Sabah Abdel Amir Jassim, Stephen Paul Denyer, Gordon Sydney Anderson Birnie Stewart
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Patent number: 6350474Abstract: The invention deals with phosphate water solution with cold solidification capacity. Phosphate composition containing iron oxide solution in acid, water, advantages from the following properties; it contains orthophosphorus acid and in addition metal powder. Phosphate composition is ecologically pure product, non toxic, non cancerogenic, non-allergic. It has antimicrobial, antivirus and fungicidal properties. Phosphate composition can be applied within medicine: surgery, dermatology, dentistry, oncology, pharmacology and other branches. In agriculture use: as a means of curing plant diseases, within veterinary—as a means for preventive maintenance and curing of animal diseases, within construction—as an anticorrosive, fire-resistant, hydro-electric isolating covers, ceramic tiles, concretes, which protect against radiation, as well as for producing other composite materials.Type: GrantFiled: June 7, 1999Date of Patent: February 26, 2002Inventors: David Dzneladze, Andro Dzneladze, Nargisa Jabishvili
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Publication number: 20010047034Abstract: The invention provides methods for inhibiting oxidative degradation of pharmaceutical formulations comprising at least one oxidation-susceptible active drug ingredient which methods comprise adding an oxidation-inhibiting amount of a ferrous ion source, preferably in the form of a pharmaceuticalexcipient, to the formulation.Type: ApplicationFiled: March 9, 2001Publication date: November 29, 2001Inventor: Hai Wang
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Patent number: 6306384Abstract: The present invention relates to a method for preventing or treating skin damage which comprises applying to the skin a composition containing an effective amount of a cosmetically or pharmaceutically acceptable compound capable of acting as an electron donor, simultaneously or substantially simultaneously with the application of a composition containing an effective amount of a cosmetically or pharmaceutically acceptable compound capable of acting as an electron acceptor, whereby an exchange of electrons between the electron donor and electron acceptor results in generation of an electrical current on the skin.Type: GrantFiled: October 1, 1996Date of Patent: October 23, 2001Assignee: E-L Management Corp.Inventors: Konstantinos M. Lahanas, Daniela Toma, Joseph Gubernick, Gheorghe Cioca
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Patent number: 6306201Abstract: This invention relates to a bivalent iron compound comprising a bivalent iron salt, an amino acid and a reducing material. It is known that bivalent iron salts exhibit specific effects in wide applications, for example, agricultural applications such as modification of soil quality, fishing applications such as quality preservation of fishes, medical applications such as treatment of diseases and industrial applications such as prevention of metal corrosion and purification of waste water and exhaust gas. However, the conventional bivalent iron salts suffer a problem that they cannot exhibit such effect for extended periods. This invention was successful in chemically stabilizing the bivalent iron salts by adding amino acids and reducing materials so as to sustain the effects inherent in the bivalent iron salts and to enable utilization thereof in industrial applications.Type: GrantFiled: June 7, 1999Date of Patent: October 23, 2001Assignee: I.B.E. Company, Ltd.Inventor: Shinzi Makino
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Patent number: 6287541Abstract: The invention relates to an oral care composition with antiplaque agents. The antiplaque agents are complexes of divalent copper, zinc, iron or tin, or trivalent iron with a specific class of cyclic &agr;-hydroxyketones. A typical example is the copper (II)-ethylmaltol complex. These complexes are more active antiplaque agents that e.g. copper-hinokitiol complexes.Type: GrantFiled: September 23, 1999Date of Patent: September 11, 2001Assignee: Chesebrough-Pond's USA Co., divison of Conopco, Inc.Inventors: Jonathan E. Creeth, Keiran Molloy, Philip Wright
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Patent number: 6288116Abstract: L-arginine found essential to enhance the glomerular function of the kidneys is used to formulate a low viscosity, calorie-dense, nutritional product for a person having renal failure. In a product free of citric acid or citrates, for oral ingestion, the taste of arginine is counteracted by lactic, malic or adipic acid; in a formulation for tube-feeding, citric acid and citrates in a specified ratio controls the product's stability. The ratio of calcium to phosphorus is controlled, as is the caloric distribution and water content; the amounts of vitamins and minerals included provide a nutritionally complete formulation.Type: GrantFiled: May 13, 1998Date of Patent: September 11, 2001Assignee: Novartis Nutrition AGInventors: Carol Jo Lowry, Kathy Marie Sass
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Publication number: 20010019727Abstract: A biocidal material comprising, as an active ingredient, a compound represented by General Formula (1)Type: ApplicationFiled: December 13, 2000Publication date: September 6, 2001Applicant: Secretary, Agency of Industrial Science and Technology & Tomita Pharmaceutical Co., Ltd.Inventors: Yoji Makita, Osamu Ikai, Kenta Ooi, Akinari Sonoda, Masahito Taya, Motomu Nishioka, Akira Ookubo, Mikiko Mihara
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Patent number: 6251417Abstract: An inorganic antimicrobial composition has the formula AB2O4, wherein A and B are low temperature far infrared irradiating metals, A is Mg, Zn, Mn, Ni, Co, or Fe(II), B is Al, Cr(III), Mn(III) or Fe(III), and O is oxygen. An antimicrobial article is made by coating said composition on a porous honeycomb-shaped substrate. An organic antimicrobial article is made from a quarternary ammonium salt coated on a porous honeycomb-shaped substrate. Processes of making the antimicrobial articles are provided.Type: GrantFiled: July 19, 1999Date of Patent: June 26, 2001Inventors: Yen-Kuen Shiau, Chung-Hsun Wu
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Patent number: 6248369Abstract: A water soluble copper salt, preferably cupric sulfate pentahydrate, is mixed with water. A small quantity of an acidic flocculant is added to the copper sulfate solution to acidify the water and promote dissolving of the copper sulfate in the water. A 25-50% water solution of an acidic flocculant, with or without a cationic polymeric flocculant aid, is prepared and pumped into a processing vessel or tank. The acidified copper sulfate solution is added to the tank and mixed with the acidic flocculant. The algicide-flocculant solution is transported to a municipal water plant and added to raw water in the clarifier to drop out particulates in the incoming water and control algae in the clarifier.Type: GrantFiled: April 6, 1998Date of Patent: June 19, 2001Assignee: Bay Chemical and Supply CompanyInventors: Thomas J. Nier, Tosby L. Linn
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Patent number: 6221403Abstract: A topical composition for impregnating a bandage comprises zinc oxide in a stable oil in water emulsion. The emulsion comprises one or more fats or oils, one or more emulsifying agents, at least one water soluble gum and water. No preservative is required.Type: GrantFiled: February 8, 1995Date of Patent: April 24, 2001Assignee: Seton Healthcare Group PLCInventor: Michael Robert Nesbit
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Patent number: 6203821Abstract: An active water is disclosed, comprising water having a substance containing a divalent and trivalent iron salt component and an organogermanium compound and/or a seawater concentrated solution contained therein, the active water of the invention possessing superior functions including pharmacological and physiological functions and being effective for the medicinal use.Type: GrantFiled: May 27, 1997Date of Patent: March 20, 2001Inventor: Ryodo Kijima
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Patent number: 6200607Abstract: A pharmaceutical product comprises the use of a combination of tyrosine and iron for separate, sequential or simultaneous administration for the treatment of Parkinson's disease or depression. In a preferred embodiment the product also contains at least one of a vitamin B6 (e.g. pyridoxine), a folate (e.g. folic acid), a vitamin B3 (e.g. nicotinamide), or zinc. The product enables the natural biosynthesis, secretion, transport and action of dopamine.Type: GrantFiled: September 13, 1999Date of Patent: March 13, 2001Inventor: Keith Bridgeman
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Patent number: 6197815Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.Type: GrantFiled: March 18, 1998Date of Patent: March 6, 2001Assignee: J.H. Biotech, Inc.Inventor: Hsinhung John Hsu
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Patent number: 6187316Abstract: Antiviral and antifungal compositions comprising a mixture of a ferrous salt and an aqueous plant extract of pomegranate rind, Viburnum plicatum leaves or flowers, tea leaves or maple leaves are disclosed.Type: GrantFiled: August 25, 1998Date of Patent: February 13, 2001Assignee: Merck Patent GmbHInventors: Sabah Abdel Amir Jassim, Stephen Paul Denyer, Gordon Sydney Anderson Birnie Stewart
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Patent number: 6187347Abstract: A composition and method of arresting the flow of blood and other protein containing body fluids flowing from an open wound and for promoting wound healing. In the method, a substantially anhydrous compound of a salt ferrate is provided for a unique use which will hydrate in the presence of blood and body fluid to produce Fe+++ thereby promoting clotting when applied to the wound for a time sufficient to arrest substantial further blood and other body fluid flow from the wound. The compound is formed of a salt taken from the group consisting of H, Li, Na, K, Rb, Cs and Fr. However, to decrease or eliminate stinging sensation, the compound may be formed having a salt taken from the group consisting of Be, Mg, Ca, Sr, Ba, Ra, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Ge, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, In, Sn, Hf, Ta, W, Re, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Al, As, NH4 and N(C4H9)4.Type: GrantFiled: February 9, 2000Date of Patent: February 13, 2001Assignee: EcoSafe, LLC.Inventors: James A. Patterson, James W. Reding, John A. Thompson, James V. Benson
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Patent number: 6103126Abstract: The present invention concerns the use of an adsorbent material modified with polynuclear metal oxyhydroxides for the selective elimination of inorganic phosphate from liquids, in particular from body fluids containing protein such as whole blood, plasma, liquid contents of the intestine as well as from dialysis fluid, as well as a process for the production of a pharmaceutical agent for oral application for the selective removal of inorganic phosphate in which an adsorbent material used according to the present invention, as such or pressed into powder form, is coated with a layer resistant to gastric acid or dispensed into an acid-resistant capsule. In order to selectively eliminate inorganic phosphate in an extracorporeal perfusion system, a body fluid such as whole blood or plasma is passed over one of the adsorbent materials.Type: GrantFiled: September 1, 1998Date of Patent: August 15, 2000Assignee: SeBo GmbHInventors: Karl-Siegfried Boos, Dietrich Seidel, Klaus Spengler, Gudrun Henke, Andreas Rauh
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Patent number: 6048515Abstract: Modular iron-containing nanoparticles are disclosed, as well as their production and use in diagnosis and therapy. The nanoparticles are characterised in that they have an iron-containing core, a primary coat (synthetic polymer) and a secondary coat (target polymer), and optional auxiliary pharmaceutical substances, pharmaceuticals and/or adsorption mediators.Type: GrantFiled: June 25, 1997Date of Patent: April 11, 2000Assignees: Institut fur Diagnostikforschung GmbH, Der Freien Universitat BerlineInventors: Mayk Kresse, Detlev Pfefferer, Rudiger Lawaczek, Susanne Wagner, Wolfgang Ebert, Volker Elste, Wolfhard Semmler, Matthias Taupitz, Josef Gaida, Anja Herrmann, Monika Jukl, Udo Swiderski
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Patent number: 6004926Abstract: A body fat percentage-lowering, body composition-improving food composition comprising 10-65 weight % of protein, 5-25 weight % of fat, and 15-70 weight % of carbohydrate, all on a dry weight basis, which composition is to be taken before, during, and/or after exercise, particularly after exercise preceding a resting period, and a method for lowering body fat percentage and improving body composition through utilization of the above food composition.Type: GrantFiled: January 23, 1998Date of Patent: December 21, 1999Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Seiichi Shimizu, Yasuyuki Yoshioka, Koji Okamura, Tatsuya Doi
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Patent number: 5972987Abstract: A method for removing lice eggs from the hair of an infested human or animal using a nit-visualizing composition. The composition involves the use of certain dyes which have an affinity to the surface of nits, to thereby enable a second individual to more easily see and remove the eggs during a combing or other removal process. To effectuate this purpose, a colored material is dispersed within a water- or alcohol-based solvent and, in one embodiment, a liquefied propellant as well. The composition is applied to the hair of the infested human or animal, and then removed after drying by a process of brushing or washing. However, the colored material which adsorbs to the chitinous exoskeleton and binding cement of the lice eggs remains on the nits, thereby facilitating visual identification and removal of the lice eggs from hair.Type: GrantFiled: March 16, 1999Date of Patent: October 26, 1999Assignee: Lori Fox ReidInventors: Lori Fox Reid, Robert D. Kross
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Patent number: RE36784Abstract: Sulforaphane has been isolated and identified as a major and very potent phase II enzyme inducer in broccoli (Brassica oleracea italica). Sulforaphane is a monofunctional inducer, inducing phase II enzymes selectively without the induction of aryl hydrocarbon receptor-dependent cytochromes P-450 (phase I enzymes). Analogues differing in the oxidation state of sulfur and the number of methylene groups were synthesized, and their inducer potencies were measured. Sulforaphane is the most potent of these analogues. Other analogues having different substituent groups in place of the methylsulfinyl group of sulforaphane were also synthesized and assessed. Of these, the most potent are 6-isothiocyanato-2-hexanone and exo-2-acetyl-6-isothiocyanatonorbornane.Type: GrantFiled: May 2, 1997Date of Patent: July 18, 2000Assignee: The Johns Hopkins UniversityInventors: Cheon-Gyu Cho, Gary H. Posner, Paul Talalay, Yuesheng Zhang