Ferrous Patents (Class 424/648)
  • Patent number: 5079010
    Abstract: A pharmaceutical preparation for oral or transdermal treatment of wounds, damaged tissue and inflammation which is a solution containing water and metallic trace elements or salts thereof in a physiological quantity.
    Type: Grant
    Filed: September 22, 1989
    Date of Patent: January 7, 1992
    Inventor: Siegfreid Natterer
  • Patent number: 5055288
    Abstract: The preparation and isolation of biodegradable superparamagnetic MR imaging contrast agents for the vascular compartment is described. These aggregates are comprised of individual biodegradable superparamagnetic metal oxide crystals which aggregates have an overall mean diameter less than about 4000 angstroms. The preferred vascular imaging contrast agent is comprised of aggregates of iron oxide crystals having an overall mean diameter less than about 500 angstroms. These contrast agents may be associated with a macromolecular species, which assist, among other things, in the preparation of these extremely small materials, and may be dispersed or dissolved in a physiologically acceptable medium. Preferred media also stabilize the materials against further aggregation even under harsh sterilization conditions.
    Type: Grant
    Filed: August 16, 1988
    Date of Patent: October 8, 1991
    Assignee: Advanced Magnetics, Inc.
    Inventors: Jerome M. Lewis, Edward T. Menz, Francis E. Kenny, Ernest V. Groman, Lee Josephson
  • Patent number: 5045304
    Abstract: A method and contrast agent for magnetic resonance imaging (MRI) of abscess. Granulocytes are separated from whole blood and incubated with an imaging vehicle such as magnetite. The granulocytes encapsulate the imaging vehicle and are suspended in an intravascularly administrable carrier to form the contrast agent. The contrast agent is highly specific for MRI of abscess.
    Type: Grant
    Filed: August 31, 1988
    Date of Patent: September 3, 1991
    Assignee: Wayne State University
    Inventors: David R. Schneider, Kostaki G. Bis
  • Patent number: 5035888
    Abstract: The mineral composition is useful for treatment of blood acidosis, peritoneal ascites and anemia. It is a combination of particulate wood ash and calcium carbonate.
    Type: Grant
    Filed: November 6, 1989
    Date of Patent: July 30, 1991
    Inventor: Tadataka Hara
  • Patent number: 5025037
    Abstract: New uses for the Oak Poison Preventive supplement, including the treatment of feline leukemia, shipping fever in cattle, and increased wool production in sheep.
    Type: Grant
    Filed: November 3, 1989
    Date of Patent: June 18, 1991
    Inventor: William H. Livingston
  • Patent number: 4994283
    Abstract: Nutritional mineral supplements comprise iron compounds and calcium compounds in combination with citrates or tartrates, ascorbates, and, optionally, fructose. The tendency of calcium to inhibit the bioavailability of iron is reduced in such compositions, so that conjoint bioavailability of these two important minerals is enhanced.
    Type: Grant
    Filed: December 20, 1988
    Date of Patent: February 19, 1991
    Assignee: The Procter & Gamble Company
    Inventors: Haile Mehansho, Kenneth T. Smith
  • Patent number: 4970079
    Abstract: Oxy-iron compounds are useful for the treatment and prevention of hyperphosphatemia. Such compounds, particularly those exhibiting high surface area, can be administered orally to bind and inhibit absorption of dietary phosphate, or such compounds can be contacted with the dialysate in a hemodialysis unit to enhance reduction of serum phosphate of patients undergoing hemodialysis.
    Type: Grant
    Filed: June 5, 1989
    Date of Patent: November 13, 1990
    Assignee: Purdue Research Foundation
    Inventors: Stanley L. Hem, Joseph L. White
  • Patent number: 4943432
    Abstract: A composition for the treatment of psoriasis and other skin diseases comprising a salt mixture of defined purity, which is applied to the diseased skin in solution or in gelled form. The composition may be characterized as composed primarily of a mixture of a magnesium halide, such as magnesium chloride, with mixed alkali and alkaline earth metal salts such as sodium and potassium chloride and/or bromide and calcium chloride or bromide. Other cations present in the mixture include strontium, aluminum, iron, lithium and zinc, and the anions include sulphate, hydrogen carbonate, borate, fluoride, silicate, iodide and carbonate.
    Type: Grant
    Filed: August 24, 1988
    Date of Patent: July 24, 1990
    Inventor: Hans F. Biener
  • Patent number: 4939092
    Abstract: Iron proteinaceous derivatives, obtained from ferric or ferrous salts and lysozyme with glutaric or 1,2-cyclohexanedicarboxylic anhydride and their pharmaceutical use in the oral treatment of iron-deficiency anemia, are described.
    Type: Grant
    Filed: October 27, 1988
    Date of Patent: July 3, 1990
    Assignee: Unibois S.p.A.
    Inventors: Flavio Villani, Adriano Zamboni
  • Patent number: 4931290
    Abstract: A method is disclosed for reducing the propensity of a dairy cow to develop severe milk fever upon calving comprising administering thereto a composition comprising a water-soluble calcium compound and a complexing agent for serum phosphorus.
    Type: Grant
    Filed: September 23, 1988
    Date of Patent: June 5, 1990
    Assignee: Domain, Inc.
    Inventor: Herbert J. Rebhan
  • Patent number: 4150035
    Abstract: This disclosure describes novel 5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-4-amines useful as intermediates for the preparation of animal growth regulants.
    Type: Grant
    Filed: June 5, 1978
    Date of Patent: April 17, 1979
    Assignee: American Cyanamid Company
    Inventor: Goro Asato