Abstract: Compositions comprising a manganese mineral are provided. In specific embodiments, the manganese mineral contains manganese carbonate (MnCO3), which may be in the form of rhodochrosite. The compositions may be administered topically to a subject, or in some versions by inhalation. For example, the compositions may be administered by direct contact with the subject's skin or by inhalation through the subject's nasal passages or mouth. Such application of the disclosed compositions may increase the subject's collagen synthesis, prolidase activity (an enzyme responsible for collagen function), and manganese superoxide dismutase activity (an antioxidant having manganese in its active site) in the subject.

Abstract: The present invention relates to methods and compositions for the treatment of dermatophytic conditions such as tinea pedis. Such conditions can progress through multiple stages, such as fungal and bacterial stages, making effective treatment results difficult to achieve. The invention relates to a combined therapy effective for treatment of the condition that utilizes daily administration of a balanced combination of antifungals, antiperspirants and drying agents to achieve a beneficial therapeutic effect, irrespective of the stage of the disease upon commencement of the treatment.

Abstract: Keratin protein cosmetic compositions are provided that include at least one keratin protein derived from human hair and a base cosmetic solution. Methods of treatment are also provided.

Abstract: This invention provides novel injectable compositions comprising botulinum toxin that may be administered to a subject for various therapeutic, aesthetic and/or cosmetic purposes. The injectable compositions contemplated by the invention exhibit one or more advantages over conventional botulinum toxin formulations, including reduced antigenicity, a reduced tendency to undergo unwanted localized diffusion following injection, increased duration of clinical efficacy or enhanced potency relative, faster onset of clinical efficacy, and/or improved stability.

Abstract: Methods and compositions are described for use in encouraging angiogenesis and skin healing as may be utilized in wound treatment as well as in encouragement of angiogenesis in disease. Compositions include an effective amount of at least one of a flavonoid and a chlorogenic acid that are natural extracts of Parrotia persica, or their derivatives, analogues, or homologs. Compounds based upon these natural extracts have been found to be highly effective in vascular formation and skin closure while exhibiting low toxicity.

Abstract: The invention relates to a nasally administrable composition comprising at least one active substance in magnesium-containing vesicular carrier, said carrier comprising glycol, phospholipids, water and at least one magnesium source. Methods for nasal administration of the composition, for example, for pain relief, are also provided.

Abstract: A two-phase oral care whitening composition including a hydrophobic phase and a hydrophilic phase, and methods for oral care whitening teeth with the same are provided. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor. The hydrophilic phase may include an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor. At least one of the hydrophobic phase and the hydrophilic phase may further include at least one surfactant.

Abstract: Compositions with fulvate fractions alone or in combination with growth factors, bioactive fragmented peptides, or combinations thereof are disclosed herein. Also disclosed are methods of using said compositions for the catalyzing cellular regeneration, including the healing, treatment, or prevention of skin disorders. Also disclosed are methods for extracting, isolating, and purifying fulvate fractions for use in the manufacture of said compositions.

Abstract: Provided herein are methods for improving skin quality in a subject comprising administering to the skin a pharmaceutical composition comprising a polypeptide covalently bound to a hydrophilic polymer and/or a polysaccharide covalently bound to a hydrophilic polymer.

Abstract: The invention includes a neutralized amino acid ester emulsifier, emulsions and compositions containing the emulsifier, and related methods. The emulsifier is a neutralized amino acid ester that is a reaction product of a neutral amino acid with a fatty alcohol and is represented by formula (I): wherein R1 is an alkyl group that has 6 to 24 carbon atoms; R2 is an alkyl group that has 6 to 36 carbon atoms; and the amine group of the amino acid is neutralized with an acid. The emulsifier is cationic. Also included are stable emulsions and compositions, preferably personal care compositions, that include the emulsifier and which may have pH levels of 5.5 or greater. Encompassed within the scope of the invention are methods of increasing the substantivity of a composition to a negatively charged substrate using the emulsifier, methods of emulsifying and methods of preparing a personal care composition using the emulsifier.

Abstract: The invention pertains to liposomes containing an oil-in-water emulsion of a selected combination of at least ten different essential plant oils produced with phospholipids found in human membranes and methods for treating respiratory diseases, disorders or conditions by administering the liposomes into the nose and respiratory system.

Abstract: The invention pertains to liposomes containing an oil-in-water emulsion of a selected combination of at least ten different essential plant oils produced with phospholipids found in human membranes and methods for treating respiratory diseases, disorders or conditions by administering the liposomes into the nose and respiratory system.

Abstract: Provided are cleaning compositions that may include (a) a glycine betaine amide, (b) an acidifying agent, (c) polysaccharide thickener, and (d) water. Commonly, the glycine betaine amide may include one or more compounds of formula (I): Me3N+—CH2—C(O)—NH—R X? (I) wherein R is an aliphatic group having 8 to 22 carbon atoms and X? represents an inorganic or organic anion. Commonly, the composition has a pH of no more than about 4, a viscosity of no more than about 1,500 cP at a shear rate of 10 at 25° C., and/or a viscosity of at least about 250 cP at a shear rate of 50 at 25° C. (where the viscosities are determined with a Brookfield Cone/Plate viscometer). The cleaning composition may exhibit a unique sheer thinning profile, such that the composition thins less after being sprayed onto a surface and thereby provides a longer contact time than conventional products.

Abstract: Disclosed is a method of preparing a hepatoprotective traditional Chinese medicine composition. The composition is prepared from Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Alba, Rhizoma Curcumae Longae and clam as main raw materials.

Abstract: Glitazone compounds, such as pioglitazone, are useful for topical treatment of dermatologic conditions, such as keratosis pilaris, that are associated with a decrease in number or function of sebocytes.

Abstract: This invention concerns a cosmetic composition comprising, in a physiologically acceptable medium, an aqueous phase, spiculisporic acid and/or one of its salts, and at least one ester of fatty acid and optionally polyoxyalkylenated (poly)glycerol. This invention further concerns the non-therapeutic, cosmetic use of the cosmetic composition as a hygienic product, makeup, a cleaning product, and/or care product of the skin and/or hair.

Abstract: A cosmetic cleansing composition includes a) 0.1 to 30 wt. %, based on the total weight of the cleansing composition, of a surfactant selected from the group of anionic, non-ionic, and/or zwitterionic surfactants and mixtures thereof, b) at least one partially and/or non-neutralized, unbranched, saturated and/or unsaturated carboxylic acid with a chain length of 14 to 30 carbon atoms, and c) at least one non-ionic polymer of the formula (I) as set forth herein, where R represents a hydrogen atom or a methyl group and n represents a whole number value from 1,360 to 99,000. The cleansing composition has a mousse-like texture and excellent cleansing and care properties.

Abstract: The present invention relates generally to methods of use and compositions useful for treating skin. The composition includes a combination of one or more of Butyrospermum parkii (shea butter), PEG-50 shea butter, glycerin, Helianthus annuus (sunflower) seed oil, Prunus armeniaca (apricot) kernel oil, acrylates copolymer, sodium lauryl sulfate, lauramidopropyl betaine, sodium methyl cocoyl taurate, glycerin, and polyquaternium-7.

Abstract: [Object] The present invention has an object to provide an external dermal agent for reducing skin yellowness already generated in the skin. [Means to Attain the Object] The above object is solved by providing an external dermal agent for reducing skin yellowness already generated in the skin, which contains hesperetin and/or glycosyl hesperetin as an effective ingredient(s).

Abstract: The invention relates to a method for applying a cosmetic composition to hair. The method comprises the steps of removing a cosmetic composition from a sealed container, the composition comprising: a post-foaming emulsion comprising a weak acid, a weak base, a fatty acid, and a volatile buffering agent; a film forming agent; and an aqueous carrier; applying said composition to one or more eyelashes; and during or after said application to said one or more eyelashes, said cosmetic composition forms a foam, said foam resulting from the release of a gas, said gas being a reaction product of said post-foaming emulsion, and said reaction commencing after the evaporation of said volatile buffering agent, upon exposure of said cosmetic composition to atmospheric conditions.

Abstract: The invention relates to a topically applied cosmetic reductive composition containing up to 20 wt. % of hydrolyzed keratin and sulphur. The remaining components are: water, compatibilizers, surfactants, thickeners, preservatives and/or aromatics. The cosmetic composition can be used to reduce adipose tissue in different areas of the body.

Abstract: The disclosure concerns a hair conditioning composition for permanent and semi-permanent hair color applications wherein the hair conditioning composition comprises a solvent; a water-soluble, oligo-peptide from a natural proteinous raw-material source containing Sulfur; alkaline or alkaline earth metal ions; a multidentate ligand or chelating agent and optionally a redox-active inorganic or organic component.

Abstract: An association comprising a peptide is described containing the sequence A-Lys-Gly-His-Lys-NH2 (SEQ ID NO: 1), wherein A is the radical corresponding to a C1 to C18 saturated or unsaturated fatty acid, and glyceryl laurate or one of the derivatives thereof. The use thereof for stimulating hair growth is also described.

Abstract: Liposomal and/or nano-liposomal encapsulated HSP90a, HPf polypeptide (115 aa) and novel polypeptides HPf ?C1 (101 aa) and HPf?C2 (87 aa), as well as methods for manufacturing/preparing and using the compositions, are disclosed. Chimeric fusion proteins that include an HSP90a, HPf-polypeptide, HPf ?C1 or HPf?C2 polypeptide are presented. Transformed cell lines and expression vectors capable of expressing the chimeric fusion proteins, are provided. Methods for producing large amounts of recombinant HSP90a, HPf polypeptide, HPf ?C1 or HPf?C2 polypeptide, using expression vectors and transformed cell lines, are described. Topical and other delivery form preparations and methods for using the preparations, including methods for improving skin conditions (atopic dermatitis, wrinkles, skin elasticity, dark spots (over pigmentation), overall skin rejuvenation, skin ageing) for therapeutic and cosmeceutical uses are presented.

Abstract: The present invention concerns a cell-enriched fat graft and methods of making and using the same. The present invention also provides a kit for making and using the cell-enriched fat graft of invention.

Abstract: The disclosure relates to topical compositions comprising a flavonoid compound and a vitamin B3 compound, and optionally a hydrolyzed silk protein or fragment thereof, which are useful for improving the health and appearance of aging skin An exemplary composition contains quercetin, hydrolyzed silk sericin and niacinamide.

Abstract: Multifunctional green and antimicrobial compositions are described containing cationic glycine betaine esters and/or cationic glycine betaine amides. Particular glycine betaine esters and amides are alkyl(ene) betainate methane sulfonates and betainyl amino alkyl(ene) methane sulfonates. The glycine betaine components are cationic, have a hydrophobic group attached to a carboxylate group through an ester or amide linkage, and are derived from a natural source, such as sugar beets. The glycine betaine esters and amides serve as cationic surfactants which have effective antimicrobial activity. The surfactant compositions are effective as crude mixtures or semi-purified mixtures or purified surfactant compounds of glycine betaine components. The addition of sodium chloride or potassium chloride or magnesium chloride or natural gum or polysaccharide to compositions containing the cationic glycine betaine ester and/or glycine betaine amide derivatives serves to thicken or gel the composition.

Abstract: The invention provides methods of hair loss or inducing new hair growth, as well as methods of preventing hair loss, comprising applying an effective amount of a dihydromyricetin compound to the scalp. The invention also provides methods of delaying or reversing signs of aging skin comprising applying an effective amount of a dihydromyricetin compound to the skin. Also provided are cosmetic products (e.g., skin and hair products) comprising a dihydromyricetin compound and methods of making the same.

Abstract: Composition containing an aqueous phase and an emulsifying system, where the emulsifying system contains at least one C10-C30 alkyl phosphate and at least one C8-C24 fatty alkyl ether of polyethylene glycol, the ether comprising from 1 to 19 ethylene glycol units and having an HLB<8 at 25° C. Process for making up or for non-therapeutically caring for keratin fibres, via the application to keratin fibres of the composition. Uses of the composition in particular for obtaining uniform and/or thick makeup on keratin fibres, and as mascara for making up keratin fibres.

Abstract: A method for promoting hair growth in a human in need of promoting hair growth. The method includes preparing a composition comprising a therapeutically effective amount of at least three of: a Bone Morphogenetic Protein, Transforming Growth Factor Beta, Platelet Derived Growth Factor, Insulin-like Growth Factor, Basic Fibroblastic Growth Factor and Vascular Endothelial Growth Factor; and administering the composition to the human.

Abstract: The present invention concerns the use of a glycosaminoglycan association of hyaluronic acid and chondroitin sulfate for the preparation of oral compositions for the prevention or for the treatment of upper gastro-intestinal tract disorders and for the preparation of upper gastro-intestinal epithelial damage, as well as the oral compositions comprising said glycosaminoglycan association.

Abstract: A method for stimulating collagen synthesis in aging skin cells in need of treatment by topically applying a composition comprising at least one extract from Laminaria genus, at least one extract from the Narcissus genus, and at least one peptide that stimulates sirtuin 6 activity in the form of a peptide or a yeast extract where the peptide is component of the extract; and a treatment composition comprising at least one extract from Laminaria genus, at least one extract from the Narcissus genus; and at least one peptide that stimulates sirtuin 6 activity.

Abstract: A hair treatment formulation comprises a plurality of composite nanoparticles in solution. The composite nanoparticles of at least one alternative embodiment are specifically prepared having a first inner polymeric gel layer comprising one or more acidic component, a second inner polymeric gel layer comprising one or more thiolate reactant having a carboxylic group, and an outer polymeric gel layer comprising peptides formed one or more amino acids of hydrolyzed keratin protein. At least one treatment component is embedded in at least one of the first inner polymeric layer, second inner polymeric layer, or the outer polymeric gel layer. Alternative methods of preparing a hair treatment formulation comprising composite nanoparticles is disclosed along with alternative methods of use of the alternative hair treatment formulations comprising a plurality of composite nanoparticles.

Abstract: Nanoparticles which are comprised of a protein-poly(alkyl-cyanoacrylate) or protein-poly(alkenyl-cyanoacrylate) copolymer may be used as a surface treatment to alter the wetting properties of a variety of different materials. The nanoparticles are produced by the method comprising: a) providing a solution of a protein in an aqueous organic solvent mixture such as an acidified aqueous alcohol; b) adding an alkyl- or alkenyl-cyanoacrylate and mixing under conditions effective to react with the protein and produce the nanoparticles comprised of a protein-poly(alkyl-cyanoacrylate) or protein-poly(alkenyl-cyanoacrylate) copolymer; and c) recovering the nanoparticles. The nanoparticles are amphiphilic, and may alter the surface-wetting properties of an object when applied onto the surface thereof. When applied onto hydrophobic surfaces, the nanoparticles render the surfaces hydrophilic.

Abstract: The present invention relates to the use of a composition comprising at least one peptidic fava bean extract as an active agent capable of limiting hair loss, and/or stimulating its growth. Moreover, the composition is intended, on one hand, to modulate the Clock, Perl and Bmal1 genes in the dermal papilla cells, and, on the other hand, to restore the circadian rhythm and resynchronize the biological clock of said cells. Finally, the present invention relates to several methods of non-therapeutic cosmetic treatment using said composition.

Abstract: Cosmetic compositions containing a) at least one first quaternary ammonium compound from the group of quaternized collagen hydrolysates; b) at least one second quaternary ammonium compound which differs from a), c) at least one film-forming polymer, d) water are suitable as heat-protection agents in the thermally assisted temporary deformation of keratinic fibers.

Abstract: Compounds of general formula (I): R1—Wn—Xm-AA1-AA2-AA3-AA4-AA5-AA6-AA7-Yp—Zq—R2, their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, preparation processes, cosmetic or pharmaceutical compositions which contain them and their use in medicine, particularly in the treatment and/or prevention of pain, inflammation, itching, neurological, compulsive and/or neuropsychiatric diseases and/or disorders and in processes of treatment and/or care of the skin, hair and/or mucous membranes mediated by neuronal exocytosis.

Abstract: Hair care and styling compositions that can provide shine, frizz control and temporary styling benefits. More specifically, it relates to hair treatment compositions that comprise of viscoelastic particles in an aqueous carrier or a mixture of water with organic or silicone carrier.

Abstract: Peptides of general formula (I): R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zs-R2 their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, their preparation process, cosmetic or pharmaceutical compositions which contain them and their use in the treatment and/or care of conditions, disorders and/or diseases that are a consequence of muscle contraction.

Abstract: Hair can be damaged in a number of ways including exposure to heat, bleaching, use of shampoos and styling products, brushing and combing, and exposure to the environment, for example ultra-violet light. Existing treatments designed to repair damaged hair make use of surface active materials that mask the problem rather than actually repairing the hair. These materials modify fibre feel by changing consumer perceivable fibre sensory cues such as smoothness, may change some measurable physical properties such as hydrophobicity and hydrophilicity, but do not change other physical characteristics such as fibre stiffness, strength or structural integrity. The invention relates to a method of repairing hair fibres using flavonoids, hydrogen peroxide and a peroxidase enzyme.

Abstract: Use of the combination of the tyrosine-arginine dipeptide or derivatives thereof and of niacinamide as a substance P antagonist for treating red blotches on the skin, skin oedema and sensitive skin. Use of this combination for the preparation of a composition for use in treating disorders associated with an excess synthesis and/or release of substance P.

Abstract: Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following amino acid sequence: a1b1c1b2a2b3 db4a3b5c2b6a4 where: a1 to a4 each represent a basic amino acid residue; b1 to b6 each represent an uncharged polar amino acid residue and/or a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue; c1 and c2 each represent an acidic amino acid residue; and d represents a hydrophobic amino acid residue.

Abstract: A method for cleaning, benefiting, or deodorizing skin or hair utilizing a body wash, skin cleaner, soap, shampoo or deodorizer formulation containing a controlled release skin benefit or deodorizing salt, a hydrophilic moisturizing polymer and surfactants is described. The method imparts benefits or deodorizing agents to the skin or hair and maintains effective levels for an extended period.

Abstract: Short single chain peptides having affinity for a target surface often lack the binding durability required for certain commercial applications. One way to improve durability is to promote multivalent binding by linking together binding sequences using peptide linkers. However, the resulting single chain binding peptides often suffer from linker entropy. It has been discovered that the use of rigid peptide linkers when linking together multiple binding sequences enhances the binding affinity of the resulting single chain peptide.

Abstract: The invention relates to peptide derivatives of general formula (I): R1-AA1-AA2-R3-AA4-R2??(I) their stereoisomers, mixtures thereof, and their cosmetically or pharmaceutically acceptable salts, a method for obtaining them, cosmetic or pharmaceutical compositions containing them and their use for the treatment, care and/or cleansing of those conditions, disorders and/or pathologies of the skin, mucosae, scalp and/or nails resulting from microorganism proliferation or being at risk of microorganism proliferation.

Abstract: Hair styling composition comprising a styling active comprising polyimide-1 and a polyvinylmethyl ether/maleic acid, and a scleroprotein.

Abstract: A hair treatment formulation comprises a plurality of composite nanoparticles in solution. The composite nanoparticles are specifically prepared having an inner core, comprising at least one protein, an intermediate starch-thiolate layer, and an outer layer comprising chitosan or modified chitosan. At least one treatment component is embedded in at least one of the inner core, intermediate layer, or outer layer. A method of preparing a hair treatment formulation comprising composite nanoparticles is disclosed along with a method of use of a hair treatment formulation comprising a plurality of composite nanoparticles.

Abstract: Disclosed are compositions and methods that are able to increase the amount of molecular structure within the cortex of hair fibers. As result, hair fiber diameter, cross sectional area, elasticity and stiffness are all increased. The benefits are long term, surviving repeated rinsing and shampooing. These results are particularly beneficial in the treatment of fine hair.

Abstract: Compositions, formulations, kits and methods for temporarily or semi-permanently transforming the shape of individual hair filaments or keratinous fibers (curling, waving or straightening) by applying no heat or heat below about 300° F. to prevent damage to the keratinous fibers.

Abstract: The present invention relates to hair treatment compositions and methods. More particularly, the invention relates to hair treatment compositions comprising lipids and creatine. The hair treatment compositions of the present invention may be used to improve the tensile properties of hair, such as hair elasticity and strength.