Selenium Or Compound Thereof Patents (Class 424/702)
  • Patent number: 6562378
    Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among adolescents.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: May 13, 2003
    Assignee: TSAR Health Private Ltd.
    Inventor: Renjit Kumar Chandra
  • Patent number: 6555140
    Abstract: A composition for enhancing the fertility and/or libido of a male mammal is described as well as methods of enhancing fertility and libido. The composition described includes the polyamines spermine, spermidine and according to one embodiment also includes selenium.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: April 29, 2003
    Inventors: Richard J. Bendera, Leanna S. Wilson
  • Patent number: 6555142
    Abstract: A food supplement formulation comprises yi zhi ren, shan zhu yu, wu wei zi, ginseng, valerian root, passiflora incarnate, L-methionine, L-arginine, and a gender-specific complex selected from the group consisting of a mixture comprising beta-sitosteroi, saw palmetto, pollen extract, selenium, zinc, vitamin E, and lycopene, and a mixture comprising black cohosh, genistein, vitamin E, and cramp bark.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: April 29, 2003
    Inventor: Lonny S. Green
  • Publication number: 20030072819
    Abstract: Compositions and methods for enhancing the delivery of another composition, enhancing blood circulation and/or enhancing cellular metabolism are provided. The compositions comprise herbals, natural nutritional supplements, minerals and/or vitamins.
    Type: Application
    Filed: May 6, 2002
    Publication date: April 17, 2003
    Inventor: Yuanjin Tao
  • Publication number: 20030060445
    Abstract: A nutritional composition is provided which comprises oligofructose and sialyllactose.
    Type: Application
    Filed: February 7, 2001
    Publication date: March 27, 2003
    Inventor: Jeffrey L. Wilson
  • Publication number: 20030055013
    Abstract: Methods of treating patients having susceptible viral infections, especially chronic hepatitis C infection by administering to said patient a therapeutically effective amount of a combination therapy of interferon-alfa and ribavirin for a time sufficient to lower HCV-RNA in association with a therapeutically effective amount of an antioxidant therapy comprising s-adenosyl methionine, preferably S-adenosyl L-methionine, for a time sufficient to ameliorate ribavirin-related hemolysis are disclosed.
    Type: Application
    Filed: September 19, 2002
    Publication date: March 20, 2003
    Applicant: SCHERING CORPORATION
    Inventor: Clifford A. Brass
  • Publication number: 20030050287
    Abstract: The formulation comprises a combination of three estrogens and selected amount of other elements. The three estrogens include 2-hydroxyestrone, 17-beta estradiol, and estriol. The amount of 17-beta estradiol is substantially less than the amounts of 2-hydroxyestrone and estriol, both which are approximately equal in amount. The amounts of pyridoxine, folic acid, selenium and cobalt are therapeutically effective amounts.
    Type: Application
    Filed: September 12, 2001
    Publication date: March 13, 2003
    Inventor: Jonathan V. Wright
  • Publication number: 20030026851
    Abstract: In a new pharmaceutical combination, the herb, Vitex agnus-castus (chasteberry), enhances hormone balance by increasing progesterone release and, therefore, ovulation frequency. The antioxidants, green tea, vitamin E, and selenium, improve overall reproductive health. L-arginine, an amino acid, stimulates the reproductive organs by improving circulation. Folic acid, vitamins B6 and B12, iron, zinc and magnesium help promote womens' fertility. Sperms are highly susceptible to free radical or oxidative damage from environmental toxicants and natural aging. Vitamins C and E, coenzyme Q10 and selenium are all potent antioxidants that help improve sperm counts and quality. Ferulic acid, an antioxidant found in Dong quai, also improves sperm quality. Zinc and B vitamins (B6, B12 and folate) are critical nutrients in male reproductive systems for hormone metabolism, sperm formation and motility. The amino acid, L-carnitine, promotes formation of healthy sperm.
    Type: Application
    Filed: September 24, 2002
    Publication date: February 6, 2003
    Inventor: Aileen Sontag Trant
  • Publication number: 20030018066
    Abstract: The invention provides a composition and method for the prevention or treatment of mammalian prostate carcinoma using Vitamin E or Vitamin E derivatives or Vitamin E analogs and selenium or selenium salt or selenium derivatives in a combined or an uncombined form, alone or in combination with traditional therapies. The invention also provides a composition and method for the prevention or treatment of mammalian prostate carcinoma using Vitamin E or Vitamin E derivatives or Vitamin E analogs and selenium or selenium salt or selenium derivatives in a combined or an uncombined form, alone or in combination with traditional therapies to increase the levels of intracellular p21 and/or p27.
    Type: Application
    Filed: April 6, 2001
    Publication date: January 23, 2003
    Inventor: Neil E. Fleshner
  • Publication number: 20030012826
    Abstract: The present invention relates to compositions without added iron and methods for prophylactic nutritional supplementation and therapeutic nutritional supplementation. Specifically, the method involves administering to an individual a composition comprising carotenoids, vitamin E, vitamin D, vitamin C, thiamine, riboflavin, niacin, folic acid, pyridoxine, biotin, pantothenic acid, cobalamin, magnesium, manganese, zinc, selenium, chromium, copper, alpha lipoic acid, and lutein, wherein the composition is free of added iron.
    Type: Application
    Filed: October 19, 2001
    Publication date: January 16, 2003
    Inventors: John A. Giordano, Charles Balzer
  • Publication number: 20030008016
    Abstract: The present invention relates to nutritive compositions containing whey, FOS, and bovine or caprine colostrum for the creation and maintenance of a healthy intestinal flora and for the enhancement of the immune system.
    Type: Application
    Filed: May 2, 2002
    Publication date: January 9, 2003
    Inventors: Albert B. Crum, D. Dorothea Zivkovic
  • Patent number: 6497885
    Abstract: In a new supplemental combination, the herb, Vitex agnus-castus (chasteberry), enhances hormone balance by increasing luteinizing hormone (LH) and progesterone release and, therefore, ovulation frequency. The antioxidants, green tea, vitamin E, and selenium, improve overall reproductive health. L-arginine, an amino acid, stimulates the reproductive organs by improving circulation. Folic acid, vitamins B6 and B12, iron, zinc and magnesium help promote women's fertility.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: December 24, 2002
    Assignee: The Daily Wellness Company
    Inventor: Aileen Sontag Trant
  • Publication number: 20020182196
    Abstract: A nutritional supplement composition for normalizing impaired or deteriorating neurological function in humans is composed of: at least one agent which promotes synthesis of ATP and/or creatine phosphate in the body, at least one antioxidant for scavenging free radicals in at least one pathway in the body; at least one agent for normalizing or maintaining membrane function and structure in the body; at least one agent for normalizing or maintaining normal neurotransmitter function in the body; at least one agent for down-regulating cortisol action; and at least one agent for suppressing activation of apoptotic pathways in the body.
    Type: Application
    Filed: April 19, 2001
    Publication date: December 5, 2002
    Inventor: Edward Larry McCleary
  • Publication number: 20020183263
    Abstract: Trauma, surgery, inflammation, subfertility, pregnancy, lactation problems, gut disorders, infant nutrition, cancer, arthritis and other joint problems, vascular problems and cardio-or cerebro-vascular problems, ischaemia, aging, impaired immune function, burns, sepsis, malnutrition, problems with liver, pancreas or kidneys, malaria, cystic fibrosis, migraine, neurological problems, respiratory infections, improvement of sports results, muscle soreness, drug intoxication and pain can be treated with a nutritional composition containing effective amounts of ribose and folic acid, optionally combined with other components such as niacin, histidine, glutamine, orotate, vitamin B6 and other components.
    Type: Application
    Filed: June 25, 2002
    Publication date: December 5, 2002
    Applicant: N.V. NUTRICIA
    Inventors: Robert Johan Joseph Hageman, Rudolf Leonardus Lodewijk Smeets, George Verlaan
  • Publication number: 20020183382
    Abstract: A composition and method for treating hepatic steatosis, steatohepatitis, and liver diseases associated with or characterized by these conditions. The composition consists essentially of defined amounts of soluble vitamin E, mixed carotenoids and selenium and in one aspect, can include at least one additional agent for the treatment of these conditions.
    Type: Application
    Filed: May 17, 2002
    Publication date: December 5, 2002
    Inventor: Ronald J. Sokol
  • Publication number: 20020182585
    Abstract: The invention is for the combination of EDTA, cystine, selenium, Vitamin C, Vitamin E, and zinc for anti-thrombotic effect and for the effect of restoring platelet aggregation, an integral component of thrombus formation, to normal and for the monitoring of the response to therapy with the combination. Methods for use of the components and method for performing the monitoring are included. The combination and method are particularly efficacious for vascular deficiency ailments including atherosclerotic vascular disease, reduction of ischemic cerebal event, complications from surgical procedures including restenosis, neurogenerative disease, and erectile disfunction, and vascular deficiency resulting from etiology of sepsis and chronic infection.
    Type: Application
    Filed: January 8, 2002
    Publication date: December 5, 2002
    Inventors: George Kindness, F. Timothy Guilford, Brooke Schumm
  • Publication number: 20020168421
    Abstract: A composition for a dietary supplement supplies components to increase the cellular formation of ATP, and thus provide energy for cellular activity. Active ingredients include 4-aminobenzoic acid, 4-hydroxybenzoic acid, L-cysteine, L-methionine, sodium molybdate, selenium, lithium bromide, horseradish powder, and shiitake mushroom powder. The composition of the present invention is administered in an oral dosage form to increase energy in humans.
    Type: Application
    Filed: March 15, 2001
    Publication date: November 14, 2002
    Applicant: E3 LIMITED, LLC
    Inventors: Edwin B. Smith, Lance Griffin
  • Patent number: 6465517
    Abstract: The present invention describes a novel composition for the treatment of migraine, a common neurovascular syndrome, which can be elicited by functional and/or structural (symptomatic) disorders. This composition comprises taurine, coenzyme Q10 and additionally creatine, L-carnitine, certain vitamins and minerals, carbohydrates, proteins, fats and herbal extracts. Furthermore, the invention describes a method for the treatment of migraine.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: October 15, 2002
    Assignee: N.V. Nutricia
    Inventor: Luutsche Van Der Zee
  • Publication number: 20020132800
    Abstract: A dietary supplement composition for promoting healthy skin comprised of lycopene and other carotenoids, selenium, chromium and biotin.
    Type: Application
    Filed: October 30, 2001
    Publication date: September 19, 2002
    Inventors: Karl F. Popp, Samuel J. Alioto
  • Publication number: 20020128309
    Abstract: A composition for the prevention and treatment of diseases or pathological states related to the degradation of the extracellular matrix, such as including but not limited to, degenerative diseases, particularly atheriosclerosis, cancer, infection or other inflammatory diseases is disclosed, comprising preferential compounds of lysine, proline, ascorbate, and their derivatives and synthetic analogues and vitamins, pro-vitamins and trace elements.
    Type: Application
    Filed: January 16, 2001
    Publication date: September 12, 2002
    Inventor: Matthias Rath
  • Patent number: 6444700
    Abstract: In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress. The stress may be in the form of physical exertion, mental exhaustion, disease states and the like. In one embodiment, the invention relates to a nutritional composition comprising a structured glyceride component and an antioxidant system. This nutritional composition has been shown to be highly effective in reducing immune system down regulation or dysregulation as a result of stress.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: September 3, 2002
    Assignee: Abbott Laboratories
    Inventors: Stephen J. DeMichele, John W. McEwen, Steven M. Wood
  • Publication number: 20020099020
    Abstract: The present invention relates to methods and nutritional compositions for the prevention and treatment of cachexia and anorexia. The methods of the invention comprise administering a composition comprising effective amounts of &ohgr;-3 fatty acids such as alpha-linolenic acid, stearidonic acid, eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid or mixtures thereof; of branched-chain amino acids valine, leucine, isoleuciné or mixtures thereof; with or without reduced levels of tryptophan and 5-hydroxytryptophan; and of antioxidant system selected from the group comprising beta-carotene, vitamin C, vitamin E, selenium, or mixtures thereof.
    Type: Application
    Filed: December 5, 2001
    Publication date: July 25, 2002
    Inventors: Bonnie Chandler Abbruzzese, Mark Anthony McCamish, Frederick Oliver Cope, Stephen Joseph Demichele
  • Patent number: 6423349
    Abstract: Compositions comprising glutamine in combination with other nutrients, including N-acetyl-cysteine and Vitamins A, C, E are disclosed. Such compositions can be administered for promoting recovery in patients undergoing elective surgery and for treating multiple organ system failure.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: July 23, 2002
    Assignee: Baxter International, Inc.
    Inventors: J. Dale Sherratt, Joann Somerville
  • Patent number: 6416782
    Abstract: A bolus for oral administration of selenium to ruminants comprising 2% to 25% by weight of the trace mineral selenium in its elemental state and in particulate form, 70% to 97.5% by weight of an inert powdered weighting agent and, optionally, 0.25 to 5% by weight of an inert lubricant is provided.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: July 9, 2002
    Assignee: Pacific Trace Minerals, Inc.
    Inventor: Kathleen Maas
  • Publication number: 20020058073
    Abstract: Compositions and methods for treating neck or shoulder discomfort are provided. The compositions comprise singly or in combination herbals, natural nutritional supplements, minerals and vitamins. Methods of making these compositions are also provided.
    Type: Application
    Filed: June 1, 2001
    Publication date: May 16, 2002
    Inventor: Yuanjin Tao
  • Patent number: 6387412
    Abstract: A storage stable magnesium oxychloride coated granular animal feed mineral supplement composition resistant to disintegration cause by moisture absorption and attrition, comprising granular mineral nutrients useful as animal feed supplements and magnesium oxychloride coatings amounting to between 0.5 and 10.0 percent of the weight of the granules, formed on the granules of mineral nutrients by coreaction of magnesium chloride and magnesium oxide. An additional coating of between 0.2 and 2.0 percent magnesium stearate formed on the magnesium oxychloride may be used to decrease the rate of wetting of the granular animal feed mineral supplements.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: May 14, 2002
    Assignee: Agri-Nutrients Technology Group, Inc.
    Inventor: William P. Moore
  • Publication number: 20020044980
    Abstract: The present invention relates to the use of a composition comprising an oil with a high content of essential fatty acids of &ohgr;3 and &ohgr;6 type, preferably blackcurrant seed oil, and at least one compound selected from &bgr;-carotene, lycopene, tocopherol and its derivatives, tocotrienols and their derivatives, ascorbic acid and nicotinamide, as a nutritional supplement intended for preventing and/or combating the harmful effects of xenobiotics on the skin, in particular on the skin's immune system.
    Type: Application
    Filed: January 17, 2001
    Publication date: April 18, 2002
    Inventors: Dominique Castelli, Nathalie Issachar
  • Patent number: 6361800
    Abstract: This invention is directed to a multi-vitamin and mineral supplement which supplies the right amount of the right micronutrients at the right time to assure adequate intake of micronutrients needed for disease prevention and protection against nutritional losses and deficiencies due to lifestyle factors and common inadequate dietary patterns. The multi-vitamin and mineral supplement is comprised of vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, niacinamide, vitamin B6, vitamin B12, biotin, pantothenic acid, iron, phosphorus, iodine, magnesium, zinc, selenium, copper, chromium, potassium, choline, lycopene, and co-enzyme Q-10.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: March 26, 2002
    Assignee: Cooper Concepts, Inc.
    Inventors: Kenneth H. Cooper, Ishwarlal Jialal, Scott Montgomery Grundy, Walter Churchill Willett, Jacob Selhub
  • Publication number: 20020034484
    Abstract: Cosmetic/pharmaceutical compositions for promoting hair growth and/or retarding hair loss, and/or for increasing the mean diameter of strands of hair and/or decreasing the heterogeneity thereof, and/or for increasing hair density, and/or for improving the quality and/or the appearance of a head of hair, and/or for inducing repigmentation of the hair, contain thus effective amounts of intimate admixture of vitamin A, vitamin C, vitamin E, and zinc and selenium values.
    Type: Application
    Filed: July 11, 2001
    Publication date: March 21, 2002
    Inventors: Olivier de Lacharriere, Francis Pruche
  • Publication number: 20020025350
    Abstract: The invention is directed to a composition and method for correcting a dietary phytochemical deficiency, wherein the phytochemicals include sulphoraphane, naringen, hesperidin, narirutin, quercetin, &bgr;-carotene, lutein, lycopene, and isoflavones. The composition may also comprise additional vitamins and minerals.
    Type: Application
    Filed: June 12, 2001
    Publication date: February 28, 2002
    Inventors: Idrees Siddiqui, David Groh, Robin Dykhouse, Audra Davies, Carl S. Rehnborg, Kerry Stonebrook
  • Publication number: 20020009504
    Abstract: Compositions and methods for treating eye discomfort are provided. The compositions comprise singly or in combination herbals, natural nutritional supplements, minerals and vitamins. Methods of making these compositions are also provided.
    Type: Application
    Filed: June 1, 2001
    Publication date: January 24, 2002
    Inventor: Yuanjin Tao
  • Publication number: 20010049352
    Abstract: The present invention provides an enteral composition and method for providing nutrition to metabolically stressed patients. Pursuant to the present invention, the enteral composition has an increased caloric density of approximately 1.4 to 1.8 kcal/mL. The enteral composition includes a peptide based protein source, a lipid source, and a carbohydrate source.
    Type: Application
    Filed: January 10, 2001
    Publication date: December 6, 2001
    Inventors: David A. Mark, Diana Twyman, Tom Michalski
  • Publication number: 20010048948
    Abstract: The present invention relates to nutritive compositions containing whey, FOS, and bovine or caprine colostrum for the creation and maintenance of a heathy intestinal flora and for the enhancement of the immune system.
    Type: Application
    Filed: December 8, 2000
    Publication date: December 6, 2001
    Inventors: Albert B. Crum, D. Dorothea Zivkovic
  • Patent number: 6322821
    Abstract: A composition for preventing and treating milk fever in freshening cows, and a method of administering the composition. The basic composition is a mixture of water, calcium chloride, propylene glycol, B vitamins and minerals. The calcium content is lower than conventional calcium treatments used for this purpose. The propylene glycol gives the cow an energy boost and sweetens the taste so the cow does not object to it as it does to conventional gels and liquids. The B vitamins stimulate the cow's appetite. The minerals replace minerals lost in the milk and also help the cow absorb calcium. The composition of the present invention is in a liquid form and is preferably administered using a 200-300 cc drench gun. The end of the dispensing tube of the drench gun is placed between the teeth and cheek of the cow near the receptors that stimulate the esophageal groove reflex.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: November 27, 2001
    Inventor: Jack W. Register
  • Patent number: 6303651
    Abstract: A composition and method of treating cutaneous infection and resulting inflammation in animals known as hot spots and mange, respectively, as well as related veterinarian dermatological conditions. The composition includes L-glutathione and a source of selenium which act synergistically and which are included in a suitable topical carrier for topical application.
    Type: Grant
    Filed: September 23, 1999
    Date of Patent: October 16, 2001
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 6291533
    Abstract: Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: September 18, 2001
    Assignee: Vitamerica, Inc.
    Inventor: Albert M. Fleischner
  • Publication number: 20010021394
    Abstract: The present invention relates to compositions and methods of induction of a cellular stress response and a protected phenotype using heavy metal ions. The invention relates to methods of protecting a mammal against injury caused by a noxious condition by administering to the mammal a heavy metal in sufficient quantity and under appropriate conditions to induce a sufficient cellular stress response to provide protection (partial or complete) against injury caused by a noxious condition. The invention also relates to methods of inducing a cellular stress response in a mammal by administering a heavy metal in sufficient quantity and under appropriate conditions to induce a cellular stress response to protect the mammal against injury caused by a noxious condition.
    Type: Application
    Filed: January 11, 2001
    Publication date: September 13, 2001
    Inventor: George A. Perdrizet
  • Patent number: 6270774
    Abstract: The present invention relates to nutritional supplements to the human diet used to increase levels of high density lipoprotein (HDL) and calcium ions, and decrease levels of free radicals and glucose in human blood plasma. More specifically, the present invention teaches novel nutritional supplements which comprise a novel combination of specific antioxidants, barley grass extract, specific multiple vitamins and minerals, and ginkgo biloba extract, as well as methods of preparing the nutritional supplements.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: August 7, 2001
    Assignee: Viva America Marketing, Inc.
    Inventors: Houn Simon Hsia, David Fan
  • Patent number: 6270809
    Abstract: The invention provides methods for producing edible plant tissue biomasses suitable for use as nutritional supplements. The seedlings are exposed to at least one metal and normal seedling growth is interrupted prior to the eleventh day following germination to thereby produce a metal-enriched plant seedling tissue biomass. The metal-containing edible plant tissue biomasses are also provided.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: August 7, 2001
    Assignee: Phytotech Inc.,
    Inventors: Burt D. Ensley, Mark Elless, Michael J. Blaylock, Jianwei Huang
  • Patent number: 6261607
    Abstract: An herbal composition which can help promote prostate health in men is prepared from saw palmetto, green tea, pumpkin seed oil, ginger, dual urtica root extracts, selenium, watermelon and rosemary. The composition contains therapeutically effective amounts of: supercritical extracts of saw palmetto, ginger, and rosemary, regular or supercritical extracts of green tea, pumpkin seed oil and urtica; selenium; and watermelon. In addition to promoting prostate health, the herbal composition of this invention normalizes urine flow and promotes healthy sexual function and performance. The composition also contains constituents which inhibit 5-lipoxygenase, thereby promoting normal prostate cell growth, and anti-aging constituents that inactivate free radicals, thereby providing antioxidant benefits. The composition is preferably administered orally or parenterally.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: July 17, 2001
    Inventors: Thomas Newmark, Paul Schulick
  • Patent number: 6255341
    Abstract: In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress. The stress may be in the form of physical exertion, mental exhaustion, disease states and the like. In one embodiment, the invention relates to a nutritional composition comprising a structured glyceride component and an antioxidant system. This nutritional composition has been shown to be highly effective in reducing immune system down regulation or dysregulation as a result of stress.
    Type: Grant
    Filed: March 12, 1999
    Date of Patent: July 3, 2001
    Assignee: Abbott Laboratories
    Inventors: Stephen J. DeMichele, John W. McEwen, Steven M. Wood
  • Patent number: 6245360
    Abstract: A single entity product is provided for administration to persons being treated for nutritional deficiencies associated with addiction to alcohol, wherein the product is an extended-release multivitamin with minerals and trace elements in beneficial dose ranges and specifically contains thiamine and folic acid in the desired amounts of about 100 mg and 1 mg, respectively. The product may also contain riboflavin in an amount between about 1 mg and about 3 mg, pyridoxine in an amount between about 1 mg and about 3 mg, cyanocobalamin in an amount between about 6 mg and about 12 mg, biotin in an amount between about 10 mcg and about 50 mcg, niacin in an amount between about 10 mg and about 50 mg, vitamin D in an amount between about 200 IU and about 500 IU, vitamin E in an amount between about 10 IU and about 50 IU, selenium in an amount between about 5 mcg and about 50 mcg, and/or magnesium in an amount between about 100 mg and about 400 mg.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: June 12, 2001
    Inventor: John S. Markowitz
  • Patent number: 6242010
    Abstract: Compositions for remediating ano-rectal inflammatory processes, hemorrhoidal syndromes and ano-rectal wounds. The composition includes the synergistic combination of reduced glutathione and selenium as a selenoamino acid in a suitable carrier for topical applications.
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: June 5, 2001
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 6242009
    Abstract: Microbicidal formulations are described which are preferably ecologically friendly and non-toxic to mammals, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains complexes having the formula R-M, wherein R is at least one organic chelating moiety and M is at least one metal ion which is microbicidal to at least one microorganism. These complexes can disrupt microorganism activities by penetrating the natural protecting bio-films of such microorganisms through the reaction of the R-group with the organic constituents of these microorganisms while releasing M into their intra-cellular media. Thus, this process exhibits its biocidal activities from the inside-out, contrary to other methods which rely on damaging the protective biofilms.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: June 5, 2001
    Inventors: Kareem I. Batarseh, Marwan Al-Kayed
  • Patent number: 6228347
    Abstract: A gel, paste, gum or lozenge composition for oral application to human gums to prevent and reduce symptoms of gum disease. The composition includes reduced glutathione and a source of selenium.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: May 8, 2001
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 6180139
    Abstract: Nonalcoholic steatohepatitis (NASH) is a disease of the liver characterized by inflammation and damage to the liver cells. Typically, steatohepatitis involves inflammation of the liver related to fat accumulation, and mimics alcoholic hepatitis but is observed in patients who seldom or never consume alcohol. Nonalcoholic steatohepatitis can lead to serious liver damage, and ultimately cirrhosis. The present invention provides methods and compositions useful for the treatment or alleviation of nonalcoholic steatohepatitis and the pharmaceutical formulations for their administration to a human. Specifically, compositions comprised of lecithin, antioxidants and vitamin B complex are administered parenterally, most preferably by oral administration. Specific therapeutic formulations include admixtures of these compounds and specific dosage formulations include daily oral administrations of these compounds in tablet or powder forms.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: January 30, 2001
    Assignee: Viva America Marketing, Inc.
    Inventors: Houn Simon Hsia, David Fan
  • Patent number: 6159503
    Abstract: A composition comprising a dry cationic pectin salt which when suspended in water swells to heat stable particles having a mean equivalent diameter greater than 100 micrometers. Food, cosmetic, superabsorbent and skin adhesive compositions containing the dry cationic pectin salt. A process for making the dry cationic pectin salt having the steps: a) converting a pectin starting material into a pectinate in a liquid medium, b) drying the pectinate, and c) selecting conditions in steps (a) and/or (b) that allow for the production of pectinate which when suspended in water swells to heat stable particles having a mean equivalent diameter greater than 100 micrometers.
    Type: Grant
    Filed: December 2, 1993
    Date of Patent: December 12, 2000
    Assignee: Hercules Incorporated
    Inventor: Poul-Egede Glahn
  • Patent number: 6160096
    Abstract: The present invention provides a regenerated collagen fiber exhibiting a draping, luster and feel close to those of a natural protein fiber such as a human hair and capable of application of a permanent wave treatment, and a method of manufacturing the regenerated collagen fiber. The amino group and/or carboxyl group of the regenerated collagen is chemically modified to introduce a mercapto group and/or a disulfide linkage to the regenerated collagen. When subjected to a permanent wave treatment, the regenerated collagen fiber retains the waved shape.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: December 12, 2000
    Assignee: Kaneka Corporation
    Inventors: Shinichi Sakashita, Mamoru Tsugawa, Masaoki Goto, Kunihiko Matsumura, Norio Hirokawa
  • Patent number: 6153178
    Abstract: The aqueous composition for permanent hair-styling has a pH of from 6.5 to 9.5 and contains from 3 to 28% by weight of a compound of formula I, ##STR1## wherein A represents --CH.sub.2 --, --C.dbd.O--, --S--, --O-- and --NR-- and R is an alkyl group having from 1 to 6 carbon atoms or a hydroxyalkyl group having from 1 to 6 carbon atoms, m is an integer from 1 to 3 and n is an integer from 0 to 3, with the proviso that n=0 only when A is methylene; water and one or more cosmetic additive ingredient selected from the group consisting of thickening agents, anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, opacifiers, alcohols, sugars, solubilizers, stabilizers, buffer substances, perfume oils, colorants, hair conditioning and hair treatment ingredients.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: November 28, 2000
    Assignee: Wella Aktiengesellschaft
    Inventors: Guenther Lang, Beate Dannecker, Wolfgang Hanefeld, Heiko Walther
  • Patent number: 6146619
    Abstract: A process for permanently deforming keratin fibers is provided wherein the fiber is treated with 1) a keratin-reducing substance, 2) a physiologically compatible salt of an organic or inorganic acid anion and a divalent cation or Al.sup.3+, and 3) a compound selected from the group consisting of Vitamin C, Vitamin B.sub.5, derivatives thereof and mixtures thereof. The salt 2) and compound 3) can be applied in the form of a wave lotion or an intermediate treatment formulation. Also provided are wave lotions and hair treatment formulations comprising the salt 2) and the compound 3).
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: November 14, 2000
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Hans-Wolfgang Cortekar, Doris Oberkobusch